Derl3 (derlin 3) - Rat Genome Database

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Gene: Derl3 (derlin 3) Rattus norvegicus
Analyze
Symbol: Derl3
Name: derlin 3
RGD ID: 1597373
Description: Predicted to enable signal recognition particle binding activity. Predicted to be involved in several processes, including ERAD pathway; negative regulation of retrograde protein transport, ER to cytosol; and protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DERL3 (derlin 3); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Der1-like domain family, member 3; derlin-3; LOC103694875; LOC690315; similar to Der1-like domain family, member 3; uncharacterized protein LOC103694875
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,753,926 - 12,766,478 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2012,762,981 - 12,766,477 (-)EnsemblGRCr8
mRatBN7.22012,754,490 - 12,768,454 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,763,543 - 12,767,027 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2013,471,091 - 13,473,652 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,832,012 - 12,834,573 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,303,805 - 13,306,366 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd2013,084,096 - 13,086,657 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive2014,079,954 - 14,082,515 (-)NCBILyon_Normotensive
Lyon_Hypertensive2014,083,080 - 14,085,641 (-)NCBILyon_Hypertensive
F344_StmMcwi2013,093,265 - 13,095,826 (-)NCBIF344_StmMcwi
Rnor_6.02013,692,102 - 13,707,645 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,704,314 - 13,706,205 (-)Ensemblrn6Rnor6.0
Rnor_5.02015,858,297 - 15,863,183 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42013,163,287 - 13,165,848 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2014,255,751 - 14,258,312 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
1H-pyrazole  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dioxygen  (EXP)
endosulfan  (EXP)
epoxiconazole  (ISO)
folic acid  (ISO)
fructose  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
indole-3-methanol  (EXP)
isoprenaline  (ISO)
luteolin  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (EXP)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
tebuconazole  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
XL147  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16449189   PMID:19940266   PMID:22607976   PMID:25660456   PMID:26565908  


Genomics

Comparative Map Data
Derl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,753,926 - 12,766,478 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2012,762,981 - 12,766,477 (-)EnsemblGRCr8
mRatBN7.22012,754,490 - 12,768,454 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,763,543 - 12,767,027 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2013,471,091 - 13,473,652 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,832,012 - 12,834,573 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,303,805 - 13,306,366 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd2013,084,096 - 13,086,657 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive2014,079,954 - 14,082,515 (-)NCBILyon_Normotensive
Lyon_Hypertensive2014,083,080 - 14,085,641 (-)NCBILyon_Hypertensive
F344_StmMcwi2013,093,265 - 13,095,826 (-)NCBIF344_StmMcwi
Rnor_6.02013,692,102 - 13,707,645 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,704,314 - 13,706,205 (-)Ensemblrn6Rnor6.0
Rnor_5.02015,858,297 - 15,863,183 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42013,163,287 - 13,165,848 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2014,255,751 - 14,258,312 (-)NCBICelera
Cytogenetic Map20p12NCBI
DERL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,834,503 - 23,839,006 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,834,503 - 23,839,128 (-)Ensemblhg38GRCh38
GRCh372224,176,690 - 24,181,193 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,506,690 - 22,511,201 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342222,501,245 - 22,505,755NCBI
Celera228,015,749 - 8,020,256 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef227,164,611 - 7,169,120 (-)NCBIHuRef
CHM1_12224,188,905 - 24,193,409 (-)NCBICHM1_1
T2T-CHM13v2.02224,281,689 - 24,286,190 (-)NCBIT2T-CHM13v2.0
Derl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,729,232 - 75,731,775 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1075,729,247 - 75,731,775 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381075,893,398 - 75,895,941 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,893,413 - 75,895,941 (+)Ensemblmm10GRCm38
MGSCv371075,356,143 - 75,358,686 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361075,337,114 - 75,339,657 (+)NCBIMGSCv36mm8
Celera1076,938,087 - 76,940,630 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.61NCBI
Derl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554558,415,839 - 8,421,762 (+)Ensembl
ChiLan1.0NW_0049554558,415,868 - 8,418,753 (+)NCBIChiLan1.0ChiLan1.0
DERL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22333,565,313 - 33,570,562 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12236,301,966 - 36,307,067 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0224,589,448 - 4,594,628 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12222,673,908 - 22,678,451 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2222,673,908 - 22,678,444 (-)EnsemblpanPan2panpan1.1
DERL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12628,688,307 - 28,690,400 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2628,688,106 - 28,690,400 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2627,761,400 - 27,763,725 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02630,093,061 - 30,095,386 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2630,093,129 - 30,095,386 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12628,174,380 - 28,176,705 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02627,792,314 - 27,794,639 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02628,780,177 - 28,785,974 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Derl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118141,478,848 - 141,482,070 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366191,271,797 - 1,275,214 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366191,271,980 - 1,275,212 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DERL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,871,218 - 49,877,672 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11449,871,077 - 49,875,022 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,313,332 - 53,315,464 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DERL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,944,291 - 6,949,948 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,947,403 - 6,949,845 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666100423,257 - 428,076 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Derl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474710,357,627 - 10,359,779 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474710,357,560 - 10,359,779 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Derl3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11811,549,596 - 11,552,152 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Derl3
29 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:72
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000038623
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804392029865039Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804392015089182Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
MARC_9679-9680:996688523:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82012,764,575 - 12,765,356 (+)Marker Load Pipeline
mRatBN7.22012,765,137 - 12,765,917 (+)MAPPERmRatBN7.2
Rnor_6.02013,704,343 - 13,705,122NCBIRnor6.0
Rnor_5.02015,859,906 - 15,860,685UniSTSRnor5.0
RGSC_v3.42013,163,959 - 13,164,738UniSTSRGSC3.4
Celera2014,256,423 - 14,257,202UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 51 66 137 94 11 50 36 32 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC091362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC167034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000038623   ⟹   ENSRNOP00000029737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2012,763,904 - 12,766,465 (-)Ensembl
mRatBN7.2 Ensembl2012,764,466 - 12,767,027 (-)Ensembl
Rnor_6.0 Ensembl2013,704,314 - 13,706,205 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086463   ⟹   ENSRNOP00000074042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2012,764,466 - 12,767,027 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116934   ⟹   ENSRNOP00000085039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2012,762,981 - 12,766,477 (-)Ensembl
mRatBN7.2 Ensembl2012,763,543 - 12,766,893 (-)Ensembl
RefSeq Acc Id: NM_001109577   ⟹   NP_001103047
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,904 - 12,766,465 (-)NCBI
mRatBN7.22012,764,466 - 12,767,027 (-)NCBI
Dahl_SR_JrHsd2013,084,096 - 13,086,657 (-)NCBI
Lyon_Normotensive2014,079,954 - 14,082,515 (-)NCBI
Lyon_Hypertensive2014,083,080 - 14,085,641 (-)NCBI
F344_StmMcwi2013,093,265 - 13,095,826 (-)NCBI
Rnor_6.02013,703,671 - 13,706,232 (-)NCBI
Rnor_5.02015,858,297 - 15,863,183 (-)NCBI
RGSC_v3.42013,163,287 - 13,165,848 (-)RGD
Celera2014,255,751 - 14,258,312 (-)RGD
Sequence:
RefSeq Acc Id: XM_008773838   ⟹   XP_008772060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,339 (-)NCBI
mRatBN7.22012,761,747 - 12,768,453 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773839   ⟹   XP_008772061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,339 (-)NCBI
mRatBN7.22012,761,747 - 12,768,454 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773841   ⟹   XP_008772063
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,761,185 - 12,766,478 (-)NCBI
mRatBN7.22012,761,747 - 12,768,447 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773842   ⟹   XP_008772064
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,476 (-)NCBI
mRatBN7.22012,761,747 - 12,768,451 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099084   ⟹   XP_038955012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,761,185 - 12,766,339 (-)NCBI
mRatBN7.22012,761,747 - 12,768,454 (-)NCBI
RefSeq Acc Id: XM_039099085   ⟹   XP_038955013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,753,926 - 12,766,339 (-)NCBI
mRatBN7.22012,754,490 - 12,768,454 (-)NCBI
RefSeq Acc Id: XM_039099086   ⟹   XP_038955014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,339 (-)NCBI
mRatBN7.22012,761,747 - 12,768,454 (-)NCBI
RefSeq Acc Id: XM_039099087   ⟹   XP_038955015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,478 (-)NCBI
mRatBN7.22012,761,747 - 12,768,451 (-)NCBI
RefSeq Acc Id: XM_039099089   ⟹   XP_038955017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,476 (-)NCBI
mRatBN7.22012,761,747 - 12,768,453 (-)NCBI
RefSeq Acc Id: XM_063279523   ⟹   XP_063135593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,478 (-)NCBI
RefSeq Acc Id: XM_063279524   ⟹   XP_063135594
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,761,185 - 12,766,476 (-)NCBI
RefSeq Acc Id: XM_063279525   ⟹   XP_063135595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,476 (-)NCBI
RefSeq Acc Id: XM_063279526   ⟹   XP_063135596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,761,185 - 12,766,478 (-)NCBI
RefSeq Acc Id: XM_063279527   ⟹   XP_063135597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,763,908 - 12,766,478 (-)NCBI
RefSeq Acc Id: NP_001103047   ⟸   NM_001109577
- UniProtKB: G3V8X2 (UniProtKB/TrEMBL),   A6JKF8 (UniProtKB/TrEMBL),   B2RZ58 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029737   ⟸   ENSRNOT00000038623
RefSeq Acc Id: XP_038955013   ⟸   XM_039099085
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2D0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955014   ⟸   XM_039099086
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038955012   ⟸   XM_039099084
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2D0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008772061   ⟸   XM_008773839
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2D0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038955017   ⟸   XM_039099089
- Peptide Label: isoform X6
- UniProtKB: B2RZ58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008772060   ⟸   XM_008773838
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2D0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008772064   ⟸   XM_008773842
- Peptide Label: isoform X3
- UniProtKB: B2RZ58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038955015   ⟸   XM_039099087
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K732 (UniProtKB/TrEMBL),   B2RZ58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008772063   ⟸   XM_008773841
- Peptide Label: isoform X2
- UniProtKB: G3V8X2 (UniProtKB/TrEMBL),   A6JKF8 (UniProtKB/TrEMBL),   B2RZ58 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074042   ⟸   ENSRNOT00000086463
Ensembl Acc Id: ENSRNOP00000085039   ⟸   ENSRNOT00000116934
RefSeq Acc Id: XP_063135596   ⟸   XM_063279526
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K732 (UniProtKB/TrEMBL),   B2RZ58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135594   ⟸   XM_063279524
- Peptide Label: isoform X3
- UniProtKB: B2RZ58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135597   ⟸   XM_063279527
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K732 (UniProtKB/TrEMBL),   B2RZ58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135593   ⟸   XM_063279523
- Peptide Label: isoform X2
- UniProtKB: A6JKF8 (UniProtKB/TrEMBL),   G3V8X2 (UniProtKB/TrEMBL),   B2RZ58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135595   ⟸   XM_063279525
- Peptide Label: isoform X3
- UniProtKB: B2RZ58 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V8X2-F1-model_v2 AlphaFold G3V8X2 1-228 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701530
Promoter ID:EPDNEW_R12054
Type:single initiation site
Name:LOC103694875_1
Description:derlin-3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02013,706,217 - 13,706,277EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1597373 AgrOrtholog
BioCyc Gene G2FUF-4164 BioCyc
Ensembl Genes ENSRNOG00000028243 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038623 ENTREZGENE
  ENSRNOT00000038623.7 UniProtKB/TrEMBL
  ENSRNOT00000116934 ENTREZGENE
  ENSRNOT00000116934.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1540.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7303301 IMAGE-MGC_LOAD
InterPro DER1 UniProtKB/TrEMBL
  Rhomboid-like_sf UniProtKB/TrEMBL
KEGG Report rno:690315 UniProtKB/TrEMBL
MGC_CLONE MGC:189282 IMAGE-MGC_LOAD
NCBI Gene 690315 ENTREZGENE
PANTHER DER1-LIKE PROTEIN, DERLIN UniProtKB/TrEMBL
Pfam DER1 UniProtKB/TrEMBL
PhenoGen Derl3 PhenoGen
RatGTEx ENSRNOG00000028243 RatGTEx
Superfamily-SCOP SSF144091 UniProtKB/TrEMBL
UniProt A0A0G2K732 ENTREZGENE
  A0A8I6A2D0 ENTREZGENE, UniProtKB/TrEMBL
  A6JKF8 ENTREZGENE, UniProtKB/TrEMBL
  B2RZ58 ENTREZGENE, UniProtKB/TrEMBL
  G3V8X2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Derl3  derlin 3  LOC103694875  derlin-3  Data merged from RGD:9125074 737654 PROVISIONAL
2014-08-25 LOC103694875  derlin-3      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-16 Derl3  derlin 3  Derl3  Der1-like domain family, member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Derl3  Der1-like domain family, member 3  LOC690315  similar to Der1-like domain family, member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC690315  similar to Der1-like domain family, member 3      Symbol and Name status set to provisional 70820 PROVISIONAL