Gene: Tmem253 (transmembrane protein 253) Rattus norvegicus
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Symbol:
Tmem253
Name:
transmembrane protein 253
RGD ID:
1597322
Description:
Predicted to be located in membrane. Orthologous to human TMEM253 (transmembrane protein 253); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type:
protein-coding
RefSeq Status:
MODEL
Previously known as:
hypothetical protein LOC690368; LOC690368
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 15 27,180,029 - 27,182,607 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 15 27,179,740 - 27,183,056 (+) Ensembl GRCr8 mRatBN7.2 15 24,706,517 - 24,709,107 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 15 24,706,529 - 24,708,625 (+) Ensembl mRatBN7.2 Rnor_6.0 15 28,413,414 - 28,416,039 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 28,413,461 - 28,415,554 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 15 32,221,865 - 32,226,503 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 15 27,445,186 - 27,447,282 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 15 25,011,020 - 25,013,645 (+) NCBI Celera Cytogenetic Map 15 p14 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Tmem253 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of TMEM253 mRNA CTD PMID:33387578 Tmem253 Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of TMEM253 mRNA CTD PMID:28959563 Tmem253 Rat aflatoxin B1 decreases methylation ISO TMEM253 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of TMEM253 gene CTD PMID:27153756 Tmem253 Rat aristolochic acid A increases expression ISO TMEM253 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of TMEM253 mRNA CTD PMID:33212167 Tmem253 Rat benzo[b]fluoranthene increases expression ISO Tmem253 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of TMEM253 mRNA CTD PMID:26377693 Tmem253 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TMEM253 mRNA CTD PMID:25181051 Tmem253 Rat bisphenol A decreases expression ISO Tmem253 (Mus musculus) 6480464 bisphenol A results in decreased expression of TMEM253 mRNA CTD PMID:32156529 Tmem253 Rat cisplatin increases expression ISO TMEM253 (Homo sapiens) 6480464 Cisplatin results in increased expression of TMEM253 mRNA CTD PMID:27392435 Tmem253 Rat cisplatin multiple interactions ISO TMEM253 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of TMEM253 mRNA CTD PMID:27392435 Tmem253 Rat diquat increases expression ISO Tmem253 (Mus musculus) 6480464 Diquat results in increased expression of TMEM253 mRNA CTD PMID:36851058 Tmem253 Rat epoxiconazole increases expression ISO Tmem253 (Mus musculus) 6480464 epoxiconazole results in increased expression of TMEM253 mRNA CTD PMID:35436446 Tmem253 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of TMEM253 mRNA CTD PMID:33387578 Tmem253 Rat hexamethylene diisocyanate increases methylation ISO TMEM253 (Homo sapiens) 6480464 1,6-hexamethylene diisocyanate results in increased methylation of TMEM253 promoter CTD PMID:25445006 Tmem253 Rat iron dichloride decreases expression ISO TMEM253 (Homo sapiens) 6480464 ferrous chloride results in decreased expression of TMEM253 mRNA CTD PMID:35984750 Tmem253 Rat lipopolysaccharide multiple interactions ISO TMEM253 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TMEM253 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... CTD PMID:35811015 Tmem253 Rat okadaic acid decreases expression ISO TMEM253 (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of TMEM253 mRNA CTD PMID:38832940 Tmem253 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of TMEM253 mRNA CTD PMID:33387578 Tmem253 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO TMEM253 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TMEM253 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... CTD PMID:35811015 Tmem253 Rat S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO TMEM253 (Homo sapiens) 6480464 S-(1,2-dichlorovinyl)cysteine results in increased expression of TMEM253 mRNA CTD PMID:35811015 Tmem253 Rat sodium arsenite decreases expression ISO Tmem253 (Mus musculus) 6480464 sodium arsenite results in decreased expression of TMEM253 mRNA CTD PMID:37682722 Tmem253 Rat urethane decreases expression ISO TMEM253 (Homo sapiens) 6480464 Urethane results in decreased expression of TMEM253 mRNA CTD PMID:28818685
References
Genomics
Comparative Map Data
Tmem253 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 15 27,180,029 - 27,182,607 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 15 27,179,740 - 27,183,056 (+) Ensembl GRCr8 mRatBN7.2 15 24,706,517 - 24,709,107 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 15 24,706,529 - 24,708,625 (+) Ensembl mRatBN7.2 Rnor_6.0 15 28,413,414 - 28,416,039 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 28,413,461 - 28,415,554 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 15 32,221,865 - 32,226,503 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 15 27,445,186 - 27,447,282 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 15 25,011,020 - 25,013,645 (+) NCBI Celera Cytogenetic Map 15 p14 NCBI
TMEM253 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 14 21,098,836 - 21,103,724 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 14 21,098,811 - 21,103,724 (+) Ensembl hg38 GRCh38 GRCh37 14 21,566,995 - 21,571,883 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 14 20,639,343 - 20,641,723 (+) NCBI Build 36 Build 36 hg18 NCBI36 Celera 14 1,427,654 - 1,432,447 (+) NCBI Celera Cytogenetic Map 14 q11.2 NCBI HuRef 14 1,687,284 - 1,692,081 (+) NCBI HuRef CHM1_1 14 21,568,829 - 21,573,619 (+) NCBI CHM1_1 T2T-CHM13v2.0 14 15,296,249 - 15,301,137 (+) NCBI T2T-CHM13v2.0
Tmem253 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 14 52,252,309 - 52,257,244 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 14 52,253,115 - 52,257,251 (+) Ensembl GRCm39 Ensembl GRCm39 GRCm38 14 52,014,852 - 52,019,787 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 14 52,015,658 - 52,019,794 (+) Ensembl mm10 GRCm38 MGSCv37 14 52,636,540 - 52,639,462 (+) NCBI MGSCv37 MGSCv37 mm9 NCBIm37 MGSCv36 14 50,938,816 - 50,941,740 (+) NCBI MGSCv36 mm8 Celera 14 48,996,770 - 48,999,666 (+) NCBI Celera Cytogenetic Map 14 C2 NCBI cM Map 14 26.77 NCBI
Tmem253 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955550 1,862,719 - 1,866,822 (+) Ensembl ChiLan1.0 NW_004955550 1,862,781 - 1,867,230 (+) NCBI ChiLan1.0 ChiLan1.0
TMEM253 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 15 22,550,226 - 22,554,472 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 14 21,766,747 - 21,770,959 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 14 1,913,655 - 1,917,874 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3
TMEM253 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 15 18,187,622 - 18,194,700 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 15 18,187,616 - 18,193,427 (+) Ensembl canFam3 CanFam3.1 Dog10K_Boxer_Tasha 15 18,671,660 - 18,685,505 (+) NCBI Dog10K_Boxer_Tasha Dog10K_Boxer_Tasha ROS_Cfam_1.0 15 18,447,013 - 18,460,567 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 15 18,450,237 - 18,452,076 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 15 18,128,293 - 18,142,133 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 15 18,184,255 - 18,198,096 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 15 18,312,210 - 18,326,061 (+) NCBI UU_Cfam_GSD_1.0 UU_Cfam_GSD_1.0
Tmem253 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
TMEM253 (Sus scrofa - pig)
TMEM253 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 29 21,573,831 - 21,577,932 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 29 21,574,780 - 21,576,691 (+) Ensembl ChlSab1.1 Ensembl chlSab2 Vervet-AGM Vero_WHO_p1.0 NW_023666059 24,858,547 - 24,860,919 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Tmem253 (Heterocephalus glaber - naked mole-rat)
Tmem253 (Rattus rattus - black rat)
miRNA Target Status (No longer updated)
Predicted Target Of
Count of predictions: 64 Count of miRNA genes: 53 Interacting mature miRNAs: 54 Transcripts: ENSRNOT00000060521 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction