Vom2r1 (vomeronasal 2 receptor, 1) - Rat Genome Database

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Gene: Vom2r1 (vomeronasal 2 receptor, 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r1
Name: vomeronasal 2 receptor, 1
RGD ID: 1596944
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane; INTERACTS WITH bis(2-ethylhexyl) phthalate; indole-3-methanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102552478; LOC678740; similar to vomeronasal 2, receptor, 1; vomeronasal 2 receptor 1; vomeronasal 2 receptor 1 precursor; vomeronasal type-2 receptor 26-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81164,376 - 175,234 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.21775,164 - 785,885 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1689,460 - 785,885 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxPNT010000246.1173,669 - 184,395 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01195,316 - 206,030 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0PNS010000042.1276,926 - 287,663 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1328,528 - 339,378 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1168,525 - 179,346 (+)NCBILyon_Normotensive
Lyon_Hypertensive11,636,098 - 1,646,919 (+)NCBILyon_Hypertensive
F344_StmMcwi1534,076 - 544,930 (+)NCBIF344_StmMcwi
Rnor_6.010111,547,190 - 111,566,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10111,547,196 - 111,566,674 (-)Ensemblrn6Rnor6.0
Rnor_5.0170,213,410 - 70,225,921 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41245,888 - 267,011 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Cytogenetic Map1p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17382427  


Genomics

Variants

.
Variants in Vom2r1
118 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:68
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000072621, ENSRNOT00000075323
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1126564886Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1126564886Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1128483164Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 1 9 7 5 1 11 5 4 4 13 5

Sequence


Ensembl Acc Id: ENSRNOT00000072186   ⟹   ENSRNOP00000083829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1774,977 - 785,885 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075323   ⟹   ENSRNOP00000064435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl10111,547,196 - 111,566,674 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103141   ⟹   ENSRNOP00000085429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1689,460 - 785,885 (+)Ensembl
RefSeq Acc Id: NM_001099461   ⟹   NP_001092931
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81164,474 - 175,214 (+)NCBI
mRatBN7.21775,164 - 785,885 (+)NCBI
Dahl_SR_JrHsd1328,548 - 339,285 (-)NCBI
Lyon_Normotensive1168,618 - 179,326 (+)NCBI
Lyon_Hypertensive11,636,191 - 1,646,899 (+)NCBI
F344_StmMcwi1534,169 - 544,910 (+)NCBI
Rnor_6.010111,547,190 - 111,566,674 (-)NCBI
Rnor_5.0170,213,410 - 70,225,921 (+)NCBI
RGSC_v3.41245,888 - 267,011 (-)RGD
Sequence:
RefSeq Acc Id: NM_001430504   ⟹   NP_001417433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd1328,528 - 339,378 (-)NCBI
Lyon_Normotensive1168,525 - 179,346 (+)NCBI
Lyon_Hypertensive11,636,098 - 1,646,919 (+)NCBI
F344_StmMcwi1534,076 - 544,930 (+)NCBI
RefSeq Acc Id: XM_039090201   ⟹   XP_038946129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81164,376 - 175,214 (+)NCBI
mRatBN7.21775,164 - 785,885 (+)NCBI
RefSeq Acc Id: XM_063273158   ⟹   XP_063129228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81164,381 - 175,234 (+)NCBI
RefSeq Acc Id: NP_001092931   ⟸   NM_001099461
- UniProtKB: A0A8I6GC46 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064435   ⟸   ENSRNOT00000075323
RefSeq Acc Id: XP_038946129   ⟸   XM_039090201
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GC46 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085429   ⟸   ENSRNOT00000103141
Ensembl Acc Id: ENSRNOP00000083829   ⟸   ENSRNOT00000072186
RefSeq Acc Id: XP_063129228   ⟸   XM_063273158
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001417433   ⟸   NM_001430504

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R4Y3-F1-model_v2 AlphaFold M0R4Y3 1-844 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596944 AgrOrtholog
BioCyc Gene G2FUF-62501 BioCyc
Ensembl Genes ENSRNOG00000048575 Ensembl
  ENSRNOG00000067992 Ensembl
  ENSRNOG00000077957 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000081554 UniProtKB/TrEMBL
  ENSRNOG00000083093 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072186.3 UniProtKB/TrEMBL
  ENSRNOT00000144624.1 UniProtKB/TrEMBL
  ENSRNOT00000173537 ENTREZGENE
  ENSRNOT00000173537.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene 678740 ENTREZGENE
PANTHER PTHR24061 UniProtKB/TrEMBL
  VOMERONASAL 2, RECEPTOR 10-RELATED UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r1 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000048575 RatGTEx
  ENSRNOG00000067992 RatGTEx
  ENSRNOG00000077957 RatGTEx
  ENSRNOG00000081554 RatGTEx
  ENSRNOG00000083093 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A8I5ZWK7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GC46 ENTREZGENE
  A0ABK0LDN1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Vom2r1  vomeronasal 2 receptor, 1  LOC102552478  vomeronasal type-2 receptor 26-like  Data merged from RGD:7699736 737654 PROVISIONAL
2013-12-18 LOC102552478  vomeronasal type-2 receptor 26-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-07-23 Vom2r1  vomeronasal 2 receptor, 1  LOC678740  similar to vomeronasal 2, receptor, 1  Symbol and Name updated 1299863 APPROVED
2006-11-20 LOC678740  similar to vomeronasal 2, receptor, 1      Symbol and Name status set to provisional 70820 PROVISIONAL