Acot4 (acyl-CoA thioesterase 4) - Rat Genome Database

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Pathways
Gene: Acot4 (acyl-CoA thioesterase 4) Rattus norvegicus
Analyze
Symbol: Acot4
Name: acyl-CoA thioesterase 4
RGD ID: 1596753
Description: Predicted to enable fatty acyl-CoA hydrolase activity and succinyl-CoA hydrolase activity. Predicted to be involved in carboxylic acid metabolic process and succinyl-CoA metabolic process. Predicted to be active in peroxisome. Orthologous to human ACOT4 (acyl-CoA thioesterase 4); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acyl-coenzyme A thioesterase 4; LOC681337; similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,399,032 - 109,405,138 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6109,399,578 - 109,405,138 (+)EnsemblGRCr8
mRatBN7.26103,668,699 - 103,674,037 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,668,753 - 103,673,917 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6103,830,503 - 103,835,783 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,129,719 - 104,134,999 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,499,170 - 103,504,450 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,517,668 - 107,522,952 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,517,668 - 107,522,952 (+)Ensemblrn6Rnor6.0
Rnor_5.06118,021,264 - 118,026,536 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46108,075,508 - 108,080,792 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6101,498,707 - 101,503,970 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
Acetyl tributyl citrate  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
amiodarone  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azoxystrobin  (EXP)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bromobenzene  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
ciprofibrate  (EXP,ISO)
clofibrate  (EXP,ISO)
coumarin  (EXP)
coumestrol  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenofibrate  (EXP)
fenthion  (ISO)
furan  (EXP)
gemfibrozil  (EXP)
genistein  (ISO)
glafenine  (EXP)
glutaryl-CoA  (ISO)
glyphosate  (EXP)
GSK-J4  (ISO)
GW 4064  (ISO)
GW 7647  (ISO)
imidacloprid  (EXP)
indole-3-methanol  (EXP)
indometacin  (EXP)
L-ethionine  (EXP)
leflunomide  (EXP)
methotrexate  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
oleic acid  (ISO)
omeprazole  (EXP)
paracetamol  (EXP,ISO)
parathion  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
senecionine  (ISO)
sodium arsenite  (ISO)
succinyl-CoA  (ISO)
sulforaphane  (ISO)
tetrachloroethene  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (EXP)
trovafloxacin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
peroxisome  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14561759   PMID:16141203   PMID:16940157   PMID:20178365  


Genomics

Comparative Map Data
Acot4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,399,032 - 109,405,138 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6109,399,578 - 109,405,138 (+)EnsemblGRCr8
mRatBN7.26103,668,699 - 103,674,037 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,668,753 - 103,673,917 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6103,830,503 - 103,835,783 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,129,719 - 104,134,999 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,499,170 - 103,504,450 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,517,668 - 107,522,952 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,517,668 - 107,522,952 (+)Ensemblrn6Rnor6.0
Rnor_5.06118,021,264 - 118,026,536 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46108,075,508 - 108,080,792 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6101,498,707 - 101,503,970 (+)NCBICelera
Cytogenetic Map6q31NCBI
ACOT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,591,873 - 73,595,766 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,591,873 - 73,595,766 (+)Ensemblhg38GRCh38
GRCh371474,058,577 - 74,062,470 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,128,163 - 73,132,223 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1454,094,503 - 54,098,556 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,226,329 - 54,230,382 (+)NCBIHuRef
CHM1_11473,998,002 - 74,002,055 (+)NCBICHM1_1
T2T-CHM13v2.01467,799,383 - 67,803,276 (+)NCBIT2T-CHM13v2.0
Acot4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,084,028 - 84,091,497 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,085,153 - 84,095,375 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381284,037,254 - 84,044,723 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,038,379 - 84,048,601 (+)Ensemblmm10GRCm38
MGSCv371285,379,329 - 85,385,673 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361284,928,127 - 84,934,471 (+)NCBIMGSCv36mm8
Celera1285,484,852 - 85,491,186 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.01NCBI
ACOT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21574,680,646 - 74,687,296 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11473,895,275 - 73,907,168 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01454,150,843 - 54,155,119 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11473,008,597 - 73,012,673 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,008,909 - 73,012,561 (+)EnsemblpanPan2panpan1.1
ACOT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1846,889,326 - 46,894,379 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl846,852,880 - 46,911,640 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha846,573,784 - 46,580,670 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0847,118,497 - 47,125,383 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1846,786,164 - 46,791,040 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,804,351 - 46,811,227 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0847,194,704 - 47,201,587 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Acot4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864029,152,711 - 29,157,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364882,912,016 - 2,914,995 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364882,912,016 - 2,914,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100158115
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl796,868,157 - 96,949,358 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1796,941,065 - 96,945,834 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,787,631 - 102,791,737 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACOT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12450,806,736 - 50,811,294 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2450,807,212 - 50,811,181 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605338,972,271 - 38,996,921 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Acot4
31 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:81
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000013753
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)699437079125323237Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)699708426112483760Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat

Markers in Region
RH141676  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26103,672,839 - 103,673,022 (+)MAPPERmRatBN7.2
Rnor_6.06107,521,755 - 107,521,937NCBIRnor6.0
Rnor_5.06118,022,267 - 118,022,449UniSTSRnor5.0
RGSC_v3.46108,079,595 - 108,079,777UniSTSRGSC3.4
Celera6101,502,794 - 101,502,976UniSTS
RH 3.4 Map6732.89UniSTS
Cytogenetic Map6q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 58 127 91 90 59 25 59 6 271 107 3 111 81 77 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000013753   ⟹   ENSRNOP00000013754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6109,399,578 - 109,405,138 (+)Ensembl
mRatBN7.2 Ensembl6103,668,753 - 103,673,917 (+)Ensembl
Rnor_6.0 Ensembl6107,517,668 - 107,522,952 (+)Ensembl
RefSeq Acc Id: NM_001109440   ⟹   NP_001102910
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,399,854 - 109,405,138 (+)NCBI
mRatBN7.26103,668,753 - 103,674,037 (+)NCBI
Rnor_6.06107,517,668 - 107,522,952 (+)NCBI
Rnor_5.06118,021,264 - 118,026,536 (-)NCBI
RGSC_v3.46108,075,508 - 108,080,792 (+)RGD
Celera6101,498,707 - 101,503,970 (+)RGD
Sequence:
RefSeq Acc Id: XM_039112919   ⟹   XP_038968847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,399,032 - 109,404,158 (+)NCBI
mRatBN7.26103,668,699 - 103,672,444 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102910 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968847 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL81471 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013754
  ENSRNOP00000013754.3
RefSeq Acc Id: NP_001102910   ⟸   NM_001109440
- UniProtKB: D3ZIQ1 (UniProtKB/TrEMBL),   A6JDS7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013754   ⟸   ENSRNOT00000013753
RefSeq Acc Id: XP_038968847   ⟸   XM_039112919
- Peptide Label: isoform X1
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIQ1-F1-model_v2 AlphaFold D3ZIQ1 1-421 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694716
Promoter ID:EPDNEW_R5240
Type:initiation region
Name:Acot4_1
Description:acyl-CoA thioesterase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06107,517,719 - 107,517,779EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596753 AgrOrtholog
BioCyc Gene G2FUF-36844 BioCyc
BioCyc Pathway PWY-5148 [acyl-CoA hydrolysis] BioCyc
  PWY-5972 [stearate biosynthesis I (animals)] BioCyc
  PWY-5996 [oleate biosynthesis II (animals and fungi)] BioCyc
  PWY-8042 [acylceramide biosynthesis] BioCyc
  PWY3O-1801 [palmitoleate biosynthesis IV (fungi and animals)] BioCyc
BioCyc Pathway Image PWY-5148 BioCyc
  PWY-5972 BioCyc
  PWY-5996 BioCyc
  PWY-8042 BioCyc
  PWY3O-1801 BioCyc
Ensembl Genes ENSRNOG00000046864 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013753 ENTREZGENE
  ENSRNOT00000013753.6 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2240 UniProtKB/TrEMBL
  3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Acyl-CoA_thioEstase_long-chain UniProtKB/TrEMBL
  BAAT_C UniProtKB/TrEMBL
  Thio_Ohase/aa_AcTrfase UniProtKB/TrEMBL
  Thio_Ohase/BAAT_N UniProtKB/TrEMBL
KEGG Report rno:681337 UniProtKB/TrEMBL
NCBI Gene 681337 ENTREZGENE
PANTHER ACYL-COENZYME A THIOESTERASE-RELATED UniProtKB/TrEMBL
  PEROXISOMAL SUCCINYL-COENZYME A THIOESTERASE UniProtKB/TrEMBL
Pfam BAAT_C UniProtKB/TrEMBL
  Bile_Hydr_Trans UniProtKB/TrEMBL
PhenoGen Acot4 PhenoGen
PIRSF Acyl-CoA_hydro UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046864 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A6JDS7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIQ1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Acot4  acyl-CoA thioesterase 4  LOC681337  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC681337  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)  LOC679253  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)  Data merged from RGD:1590705 1643240 APPROVED
2006-11-20 LOC681337  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC679253  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)      Symbol and Name status set to provisional 70820 PROVISIONAL