Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cstf2 | Rat | X-Linked Intellectual Developmental Disorder 113 | | ISO | CSTF2 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cstf2 | Rat | X-Linked Intellectual Developmental Disorder 113 | | ISO | CSTF2 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Pre-mRNA 3'-end processing complex assembly and function. | Chan S, etal., Wiley Interdiscip Rev RNA. 2011 May-Jun;2(3):321-35. doi: 10.1002/wrna.54. Epub 2010 Oct 18. |
| 2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors. | Gruber AR, etal., Wiley Interdiscip Rev RNA. 2014 Mar-Apr;5(2):183-96. doi: 10.1002/wrna.1206. Epub 2013 Nov 14. |
| 4. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 5. | GOA pipeline | RGD automated data pipeline |
| 6. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 7. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 8. | Comprehensive gene review and curation | RGD comprehensive gene curation |
| 9. | Polyadenylation site-specific differences in the activity of the neuronal betaCstF-64 protein in PC-12 cells. | Shankarling GS and MacDonald CC, Gene. 2013 Oct 25;529(2):220-7. doi: 10.1016/j.gene.2013.08.007. Epub 2013 Aug 12. |
| PMID:1741396 | PMID:11598190 | PMID:12477932 | PMID:18305108 | PMID:21102410 | PMID:22658674 | PMID:22681889 |
| Cstf2 (Rattus norvegicus - Norway rat) |
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| CSTF2 (Homo sapiens - human) |
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| Cstf2 (Mus musculus - house mouse) |
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| Cstf2 (Chinchilla lanigera - long-tailed chinchilla) |
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| CSTF2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| CSTF2 (Canis lupus familiaris - dog) |
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| Cstf2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| CSTF2 (Sus scrofa - pig) |
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| CSTF2 (Chlorocebus sabaeus - green monkey) |
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| Cstf2 (Heterocephalus glaber - naked mole-rat) |
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| Cstf2 (Rattus rattus - black rat) |
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.
Variants in Cstf2
60 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| RH139618 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 67 | 165 | 91 | 90 | 59 | 92 | 59 | 6 | 356 | 192 | 11 | 144 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_001131014 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| NM_001434384 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001434385 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001434386 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001434387 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001434388 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008773440 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100063 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100064 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100065 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100066 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100067 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100068 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100069 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100070 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100072 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039100073 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063280303 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_005498063 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_005498064 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_005498066 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_005498067 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_005498068 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_005498069 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_010061248 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_010061249 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_010061250 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | BC168251 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| JAXUCZ010000021 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000074330 ⟹ ENSRNOP00000066513 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000079572 ⟹ ENSRNOP00000069956 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000082983 ⟹ ENSRNOP00000073796 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000098089 ⟹ ENSRNOP00000082910 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001131014 ⟹ NP_001124486 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_039100063 ⟹ XP_038955991 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100064 ⟹ XP_038955992 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100065 ⟹ XP_038955993 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100066 ⟹ XP_038955994 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100067 ⟹ XP_038955995 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100068 ⟹ XP_038955996 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100069 ⟹ XP_038955997 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100070 ⟹ XP_038955998 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100072 ⟹ XP_038956000 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039100073 ⟹ XP_038956001 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063280303 ⟹ XP_063136373 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XR_005498063 | ||||||||||||
| Type: | NON-CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XR_005498064 | ||||||||||||
| Type: | NON-CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XR_005498066 | ||||||||||||
| Type: | NON-CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XR_005498067 | ||||||||||||
| Type: | NON-CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XR_005498068 | ||||||||||||
| Type: | NON-CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XR_005498069 | ||||||||||||
| Type: | NON-CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XR_010061248 | ||||||||
| Type: | NON-CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XR_010061249 | ||||||||
| Type: | NON-CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XR_010061250 | ||||||||
| Type: | NON-CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_001124486 | (Get FASTA) | NCBI Sequence Viewer |
| NP_001421313 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_001421314 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_001421315 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_001421316 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_001421317 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038955991 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038955992 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038955993 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038955994 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038955995 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038955996 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038955997 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038955998 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038956000 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038956001 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063136373 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAI68251 | (Get FASTA) | NCBI Sequence Viewer |
| Ensembl Protein | ENSRNOP00000066513 | ||
| ENSRNOP00000066513.3 | |||
| ENSRNOP00000069956 | |||
| ENSRNOP00000069956.3 | |||
| ENSRNOP00000073796.2 | |||
| ENSRNOP00000082910 | |||
| ENSRNOP00000082910.2 |
| RefSeq Acc Id: | NP_001124486 ⟸ NM_001131014 |
| - UniProtKB: | B4F7F1 (UniProtKB/TrEMBL), M0RAG5 (UniProtKB/TrEMBL), A0A0G2K6F9 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000073796 ⟸ ENSRNOT00000082983 |
| Ensembl Acc Id: | ENSRNOP00000069956 ⟸ ENSRNOT00000079572 |
| Ensembl Acc Id: | ENSRNOP00000066513 ⟸ ENSRNOT00000074330 |
| RefSeq Acc Id: | XP_038955991 ⟸ XM_039100063 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_038955992 ⟸ XM_039100064 |
| - Peptide Label: | isoform X2 |
| RefSeq Acc Id: | XP_038955993 ⟸ XM_039100065 |
| - Peptide Label: | isoform X3 |
| RefSeq Acc Id: | XP_038956000 ⟸ XM_039100072 |
| - Peptide Label: | isoform X9 |
| RefSeq Acc Id: | XP_038956001 ⟸ XM_039100073 |
| - Peptide Label: | isoform X9 |
| RefSeq Acc Id: | XP_038955994 ⟸ XM_039100066 |
| - Peptide Label: | isoform X4 |
| RefSeq Acc Id: | XP_038955995 ⟸ XM_039100067 |
| - Peptide Label: | isoform X5 |
| RefSeq Acc Id: | XP_038955996 ⟸ XM_039100068 |
| - Peptide Label: | isoform X6 |
| RefSeq Acc Id: | XP_038955997 ⟸ XM_039100069 |
| - Peptide Label: | isoform X7 |
| RefSeq Acc Id: | XP_038955998 ⟸ XM_039100070 |
| - Peptide Label: | isoform X8 |
| Ensembl Acc Id: | ENSRNOP00000082910 ⟸ ENSRNOT00000098089 |
| RefSeq Acc Id: | XP_063136373 ⟸ XM_063280303 |
| - Peptide Label: | isoform X10 |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-A0A0G2K6F9-F1-model_v2 | AlphaFold | A0A0G2K6F9 | 1-575 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| RGD ID: | 13701938 | ||||||||
| Promoter ID: | EPDNEW_R12452 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Cstf2_2 | ||||||||
| Description: | cleavage stimulation factor subunit 2 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Alternative Promoters: | null; see alsoEPDNEW_R12453 | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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| RGD ID: | 13701929 | ||||||||
| Promoter ID: | EPDNEW_R12453 | ||||||||
| Type: | multiple initiation site | ||||||||
| Name: | Cstf2_1 | ||||||||
| Description: | cleavage stimulation factor subunit 2 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Alternative Promoters: | null; see alsoEPDNEW_R12452 | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
|
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1596566 | AgrOrtholog |
| BioCyc Gene | G2FUF-1696 | BioCyc |
| Ensembl Genes | ENSRNOG00000048025 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000074330 | ENTREZGENE |
| ENSRNOT00000074330.4 | UniProtKB/TrEMBL | |
| ENSRNOT00000079572 | ENTREZGENE | |
| ENSRNOT00000079572.3 | UniProtKB/TrEMBL | |
| ENSRNOT00000082983 | ENTREZGENE | |
| ENSRNOT00000082983.3 | UniProtKB/TrEMBL | |
| ENSRNOT00000098089 | ENTREZGENE | |
| ENSRNOT00000098089.2 | UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.10.20.70 | UniProtKB/TrEMBL |
| 1.25.40.630 | UniProtKB/TrEMBL | |
| 3.30.70.330 | UniProtKB/TrEMBL | |
| InterPro | CSTF2_C_sf | UniProtKB/TrEMBL |
| CSTF2_hinge | UniProtKB/TrEMBL | |
| CSTF_C | UniProtKB/TrEMBL | |
| Nucleotide-bd_a/b_plait_sf | UniProtKB/TrEMBL | |
| RBD_domain_sf | UniProtKB/TrEMBL | |
| RRM_dom | UniProtKB/TrEMBL | |
| KEGG Report | rno:683927 | UniProtKB/TrEMBL |
| NCBI Gene | 683927 | ENTREZGENE |
| PANTHER | CLEAVAGE STIMULATION FACTOR SUBUNIT 2 | UniProtKB/TrEMBL |
| PTHR45735:SF6 | UniProtKB/TrEMBL | |
| Pfam | CSTF2_hinge | UniProtKB/TrEMBL |
| CSTF_C | UniProtKB/TrEMBL | |
| RRM_1 | UniProtKB/TrEMBL | |
| PhenoGen | Cstf2 | PhenoGen |
| PROSITE | RRM | UniProtKB/TrEMBL |
| RatGTEx | ENSRNOG00000048025 | RatGTEx |
| SMART | RRM | UniProtKB/TrEMBL |
| Superfamily-SCOP | SSF54928 | UniProtKB/TrEMBL |
| UniProt | A0A0G2JWP1 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A0G2K6F9 | ENTREZGENE, UniProtKB/TrEMBL | |
| A0A8I5ZY65 | ENTREZGENE | |
| A0A8J8XR33 | ENTREZGENE, UniProtKB/TrEMBL | |
| B4F7F1 | ENTREZGENE, UniProtKB/TrEMBL | |
| M0RAG5 | ENTREZGENE | |
| UniProt Secondary | A0A8I5ZY65 | UniProtKB/TrEMBL |
| M0RAG5 | UniProtKB/TrEMBL |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2016-05-11 | Cstf2 | cleavage stimulation factor subunit 2 | Cstf2 | cleavage stimulation factor, 3' pre-RNA subunit 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-09-22 | Cstf2 | cleavage stimulation factor, 3' pre-RNA subunit 2 | LOC683927 | similar to cleavage stimulation factor, 3 pre-RNA subunit 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2006-11-20 | LOC683927 | similar to cleavage stimulation factor, 3 pre-RNA subunit 2 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |