Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Nicotine results in increased expression of SEC61G mRNA | CTD | PMID:16949557 | 1,2-dimethylhydrazine | decreases expression | ISO | Sec61g (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SEC61G mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of SEC61G mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Sec61g (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SEC61G mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Estradiol results in decreased expression of SEC61G mRNA | CTD | PMID:23019147 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Sec61g (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SEC61G mRNA | CTD | PMID:15056799 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Sec61g (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SEC61G mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sec61g (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SEC61G mRNA | CTD | PMID:21570461 | 2-hydroxypropanoic acid | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SEC61G mRNA | CTD | PMID:30851411 | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of SEC61G mRNA | CTD | PMID:28522335 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Sec61g (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of SEC61G mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SEC61G mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SEC61G mRNA | CTD | PMID:30047161 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of SEC61G mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SEC61G mRNA | CTD | PMID:33212167 | Aroclor 1254 | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of SEC61G mRNA | CTD | PMID:23650126 | arsenite(3-) | multiple interactions | ISO | SEC61G (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to SEC61G mRNA] | CTD | PMID:32406909 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Sec61g (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of SEC61G mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of SEC61G mRNA | CTD | PMID:31163220 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Sec61g (Mus musculus) | 6480464 | PPARA protein inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SEC61G mRNA] | CTD | PMID:19850644 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SEC61G mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | bisphenol A results in increased expression of SEC61G mRNA | CTD | PMID:38074096 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SEC61G mRNA | CTD | PMID:36041667 | bisphenol A | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SEC61G mRNA | CTD | PMID:32028606 | bisphenol A | decreases expression | ISO | Sec61g (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SEC61G mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SEC61G mRNA | CTD | PMID:29275510 | bisphenol F | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | bisphenol F results in increased expression of SEC61G mRNA | CTD | PMID:35387338 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SEC61G mRNA | CTD | PMID:36041667 | butanal | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of SEC61G mRNA | CTD | PMID:26079696 | carbon nanotube | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | chloropicrin | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | chloropicrin results in increased expression of SEC61G mRNA | CTD | PMID:26352163 | chlorpyrifos | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SEC61G mRNA | CTD | PMID:37019170 | ciguatoxin CTX1B | affects expression | ISO | Sec61g (Mus musculus) | 6480464 | Ciguatoxins affects the expression of SEC61G mRNA | CTD | PMID:18353800 | cyclosporin A | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SEC61G mRNA | CTD | PMID:20106945 and PMID:27989131 | dicrotophos | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SEC61G mRNA | CTD | PMID:28302478 | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of SEC61G mRNA | CTD | PMID:36653537 | disodium selenite | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SEC61G mRNA | CTD | PMID:18175754 | diuron | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Diuron results in decreased expression of SEC61G mRNA | CTD | PMID:35967413 | ethanol | multiple interactions | ISO | SEC61G (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of SEC61G mRNA | CTD | PMID:29432896 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SEC61G mRNA | CTD | PMID:24793618 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SEC61G mRNA | CTD | PMID:22061828 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of SEC61G mRNA | CTD | PMID:24136188 | isobutanol | multiple interactions | ISO | SEC61G (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of SEC61G mRNA | CTD | PMID:29432896 | ivermectin | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SEC61G protein | CTD | PMID:32959892 | L-ascorbic acid | decreases expression | EXP | | 6480464 | Ascorbic Acid results in decreased expression of SEC61G mRNA | CTD | PMID:15372504 | menadione | affects expression | ISO | SEC61G (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of SEC61G mRNA | CTD | PMID:20044591 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of SEC61G mRNA | CTD | PMID:30047161 | N-methyl-N'-nitro-N-nitrosoguanidine | multiple interactions | ISO | Sec61g (Mus musculus) | 6480464 | [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA | CTD | PMID:19840844 | nickel sulfate | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of SEC61G mRNA | CTD | PMID:18651567 | nicotine | increases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Nicotine results in increased expression of SEC61G mRNA | CTD | PMID:16949557 | paracetamol | affects expression | ISO | Sec61g (Mus musculus) | 6480464 | Acetaminophen affects the expression of SEC61G mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SEC61G mRNA | CTD | PMID:33387578 | phenobarbital | affects expression | ISO | SEC61G (Homo sapiens) | 6480464 | Phenobarbital affects the expression of SEC61G mRNA | CTD | PMID:19159669 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of SEC61G mRNA | CTD | PMID:30047161 | PhIP | increases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of SEC61G mRNA | CTD | PMID:15215175 | phorbol 13-acetate 12-myristate | multiple interactions | ISO | Sec61g (Mus musculus) | 6480464 | [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA | CTD | PMID:19840844 | rac-lactic acid | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SEC61G mRNA | CTD | PMID:30851411 | resveratrol | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | resveratrol results in increased expression of SEC61G mRNA | CTD | PMID:22610192 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of SEC61G mRNA | CTD | PMID:28374803 | sertraline | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Sertraline results in decreased expression of SEC61G mRNA | CTD | PMID:24865413 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of SEC61G mRNA | CTD | PMID:30047161 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of SEC61G mRNA | CTD | PMID:33387578 | titanium dioxide | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SEC61G mRNA | CTD | PMID:23557971 | titanium dioxide | decreases expression | ISO | Sec61g (Mus musculus) | 6480464 | titanium dioxide analog results in decreased expression of SEC61G mRNA | CTD | PMID:25111187 | toluene | decreases expression | EXP | | 6480464 | Toluene results in decreased expression of SEC61G mRNA | CTD | PMID:22967744 | triadimefon | increases expression | EXP | | 6480464 | triadimefon results in increased expression of SEC61G mRNA | CTD | PMID:30047161 | tungsten | increases expression | ISO | Sec61g (Mus musculus) | 6480464 | Tungsten results in increased expression of SEC61G mRNA | CTD | PMID:30912803 | urethane | decreases expression | ISO | SEC61G (Homo sapiens) | 6480464 | Urethane results in decreased expression of SEC61G mRNA | CTD | PMID:28818685 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of SEC61G mRNA | CTD | PMID:23034163 | |