Rbbp8nl (RBBP8 N-terminal like) - Rat Genome Database

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Gene: Rbbp8nl (RBBP8 N-terminal like) Rattus norvegicus
Analyze
Symbol: Rbbp8nl
Name: RBBP8 N-terminal like
RGD ID: 1596090
Description: Orthologous to human RBBP8NL (RBBP8 N-terminal like); INTERACTS WITH aflatoxin B1; alpha-Zearalanol; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC690416; similar to Protein C20orf151
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83187,741,642 - 187,756,598 (-)NCBIGRCr8
mRatBN7.23167,364,048 - 167,378,993 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3167,364,048 - 167,379,092 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03175,646,786 - 175,661,377 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3175,645,281 - 175,654,707 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03181,452,607 - 181,468,506 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43169,332,148 - 169,344,771 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3165,201,478 - 165,216,074 (+)NCBICelera
Cytogenetic Map3q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:21873635   PMID:22664934  


Genomics

Comparative Map Data
Rbbp8nl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83187,741,642 - 187,756,598 (-)NCBIGRCr8
mRatBN7.23167,364,048 - 167,378,993 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3167,364,048 - 167,379,092 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03175,646,786 - 175,661,377 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3175,645,281 - 175,654,707 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03181,452,607 - 181,468,506 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43169,332,148 - 169,344,771 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3165,201,478 - 165,216,074 (+)NCBICelera
Cytogenetic Map3q43NCBI
RBBP8NL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382062,410,237 - 62,427,539 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2062,410,237 - 62,427,539 (-)EnsemblGRCh38hg38GRCh38
GRCh372060,985,293 - 61,002,595 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362060,418,688 - 60,435,984 (-)NCBINCBI36Build 36hg18NCBI36
Build 342060,418,687 - 60,435,984NCBI
Celera2057,720,567 - 57,737,891 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2057,762,499 - 57,780,051 (-)NCBIHuRef
CHM1_12060,886,494 - 60,903,721 (-)NCBICHM1_1
T2T-CHM13v2.02064,206,781 - 64,224,245 (-)NCBIT2T-CHM13v2.0
Rbbp8nl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392179,917,039 - 179,931,693 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2179,919,439 - 179,931,672 (-)EnsemblGRCm39 Ensembl
GRCm382180,275,246 - 180,289,900 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,277,646 - 180,289,879 (-)EnsemblGRCm38mm10GRCm38
MGSCv372180,012,351 - 180,024,584 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362180,207,054 - 180,219,287 (-)NCBIMGSCv36mm8
Celera2184,360,835 - 184,373,068 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2102.8NCBI
Rbbp8nl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555281,647,199 - 1,653,035 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555281,641,291 - 1,655,920 (+)NCBIChiLan1.0ChiLan1.0
RBBP8NL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22168,195,347 - 68,213,193 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12068,188,467 - 68,206,313 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02058,794,817 - 58,812,530 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12060,095,450 - 60,112,408 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2060,095,450 - 60,112,408 (-)Ensemblpanpan1.1panPan2
RBBP8NL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,377,956 - 46,393,990 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2446,377,956 - 46,387,543 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2445,629,268 - 45,644,829 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02447,248,991 - 47,264,559 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2447,248,991 - 47,258,429 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12446,350,175 - 46,365,727 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02446,473,520 - 46,489,076 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,227,789 - 47,243,354 (-)NCBIUU_Cfam_GSD_1.0
Rbbp8nl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640194,560,849 - 194,569,986 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,017,821 - 10,023,590 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,016,227 - 10,023,590 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBBP8NL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1761,782,605 - 61,787,321 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11761,778,579 - 61,794,258 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21769,188,882 - 69,203,372 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RBBP8NL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121,801,775 - 1,820,209 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21,811,379 - 1,819,724 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605049,752,718 - 49,761,974 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbbp8nl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474128,264,987 - 28,270,846 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474128,261,578 - 28,276,715 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbbp8nl
35 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3161192952169034231Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat

Markers in Region
D3Hmgc11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23167,375,372 - 167,375,568 (+)MAPPERmRatBN7.2
Rnor_6.03175,658,110 - 175,658,305NCBIRnor6.0
Rnor_5.03181,457,189 - 181,457,384UniSTSRnor5.0
RGSC_v3.43169,340,780 - 169,340,975UniSTSRGSC3.4
Celera3165,204,551 - 165,204,746UniSTS
Cytogenetic Map3q43UniSTS
D3Hmgc12  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03175,662,852 - 175,662,977NCBIRnor6.0
Rnor_5.03181,452,518 - 181,452,642UniSTSRnor5.0
RGSC_v3.43169,345,522 - 169,345,647UniSTSRGSC3.4
Celera3165,199,879 - 165,200,004UniSTS
Cytogenetic Map3q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 39 111 91 90 59 25 59 6 208 87 91 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000080191   ⟹   ENSRNOP00000068684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3167,364,048 - 167,379,092 (-)Ensembl
Rnor_6.0 Ensembl3175,645,281 - 175,654,707 (-)Ensembl
RefSeq Acc Id: XM_039106758   ⟹   XP_038962686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83187,741,642 - 187,756,598 (-)NCBI
mRatBN7.23167,364,048 - 167,378,993 (-)NCBI
RefSeq Acc Id: XM_039106759   ⟹   XP_038962687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83187,741,642 - 187,756,598 (-)NCBI
mRatBN7.23167,364,048 - 167,378,993 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001418711 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962686 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962687 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000068684.2
Ensembl Acc Id: ENSRNOP00000068684   ⟸   ENSRNOT00000080191
RefSeq Acc Id: XP_038962687   ⟸   XM_039106759
- UniProtKB: A0A0G2JTF0 (UniProtKB/TrEMBL),   A6KMA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962686   ⟸   XM_039106758
Protein Domains
DNA endonuclease Ctp1 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTF0-F1-model_v2 AlphaFold A0A0G2JTF0 1-574 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596090 AgrOrtholog
BioCyc Gene G2FUF-46359 BioCyc
Ensembl Genes ENSRNOG00000057245 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000080191.2 UniProtKB/TrEMBL
InterPro CtIP_N UniProtKB/TrEMBL
  RBBP8-like UniProtKB/TrEMBL
NCBI Gene 690416 ENTREZGENE
PANTHER PTHR15107 UniProtKB/TrEMBL
  RBBP8 N-TERMINAL-LIKE PROTEIN UniProtKB/TrEMBL
Pfam CtIP_N UniProtKB/TrEMBL
PhenoGen Rbbp8nl PhenoGen
RatGTEx ENSRNOG00000057245 RatGTEx
UniProt A0A0G2JTF0 ENTREZGENE, UniProtKB/TrEMBL
  A6KMA6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-22 Rbbp8nl  RBBP8 N-terminal like  LOC690416  similar to Protein C20orf151  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC690416  similar to Protein C20orf151  LOC682021  similar to Protein C20orf151  Data merged from RGD:1588145 1643240 APPROVED
2006-11-20 LOC690416  similar to Protein C20orf151      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC682021  similar to Protein C20orf151      Symbol and Name status set to provisional 70820 PROVISIONAL