Zfp709l1 (zinc finger protein 709-like 1) - Rat Genome Database

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Pathways
Gene: Zfp709l1 (zinc finger protein 709-like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Zfp709l1
Name: zinc finger protein 709-like 1
RGD ID: 1596088
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; dioxygen.
Type: protein-coding (Ensembl: lncRNA)
RefSeq Status: PROVISIONAL
Previously known as: LOC100909526; LOC690419; similar to zinc finger protein 709; zinc finger protein 433-like; zinc finger protein 709-like; zinc finger protein 878; Zinki
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr878,328,854 - 8,359,100 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl78,328,861 - 8,338,418 (-)EnsemblGRCr8
GRCr8 Ensembl78,340,507 - 8,353,078 (-)EnsemblGRCr8
mRatBN7.277,683,807 - 7,708,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl77,668,997 - 7,780,109 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx710,582,749 - 10,602,086 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0712,458,410 - 12,477,747 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0710,308,008 - 10,327,283 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0710,412,577 - 10,436,946 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl710,418,602 - 10,430,992 (-)Ensemblrn6Rnor6.0
Rnor_5.0710,568,260 - 10,607,832 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.479,159,486 - 9,178,619 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera75,890,106 - 5,914,405 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19193899  


Genomics

Variants

.
Variants in Zfp709l1
104 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:18
Count of miRNA genes:9
Interacting mature miRNAs:9
Transcripts:ENSRNOT00000043099, ENSRNOT00000047433
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
AI170370  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0710,757,201 - 10,757,323NCBIRnor5.0
Rnor_5.0710,514,780 - 10,514,901NCBIRnor5.0
Rnor_5.0710,588,694 - 10,588,816NCBIRnor5.0
RGSC_v3.479,159,606 - 9,159,727UniSTSRGSC3.4
RGSC_v3.479,230,234 - 9,230,354UniSTSRGSC3.4
Celera75,966,143 - 5,966,263UniSTS
Celera75,895,233 - 5,895,354UniSTS
Cytogenetic Map7q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 90 89 58 92 58 6 353 192 11 144 79 88 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_355238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_593260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_593261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000047433   ⟹   ENSRNOP00000051405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl77,689,592 - 7,780,109 (-)Ensembl
Rnor_6.0 Ensembl710,418,602 - 10,430,992 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000063989   ⟹   ENSRNOP00000063560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl77,668,997 - 7,708,014 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086920   ⟹   ENSRNOP00000075050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl78,328,861 - 8,338,418 (-)Ensembl
mRatBN7.2 Ensembl77,678,081 - 7,708,014 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094718   ⟹   ENSRNOP00000081680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl77,681,964 - 7,708,014 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101824   ⟹   ENSRNOP00000097778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl77,757,808 - 7,780,109 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104041   ⟹   ENSRNOP00000089425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl77,678,081 - 7,708,242 (-)Ensembl
RefSeq Acc Id: NM_001163063   ⟹   NP_001156535
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,339,672 - 8,358,803 (-)NCBI
mRatBN7.277,688,889 - 7,708,020 (-)NCBI
Rnor_6.0710,417,584 - 10,436,717 (-)NCBI
Rnor_5.0710,568,260 - 10,607,832 (-)NCBI
RGSC_v3.479,159,486 - 9,178,619 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240830   ⟹   XP_006240892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,328,854 - 8,358,853 (-)NCBI
mRatBN7.277,683,807 - 7,708,070 (-)NCBI
Rnor_6.0710,412,577 - 10,436,946 (-)NCBI
Rnor_5.0710,568,260 - 10,607,832 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765131   ⟹   XP_008763353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,328,854 - 8,359,100 (-)NCBI
mRatBN7.277,683,807 - 7,708,257 (-)NCBI
Rnor_6.0710,412,577 - 10,436,937 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001838720
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,328,854 - 8,358,853 (-)NCBI
mRatBN7.277,683,807 - 7,708,070 (-)NCBI
Rnor_6.0710,412,577 - 10,436,936 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001838721
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,328,854 - 8,358,853 (-)NCBI
mRatBN7.277,683,807 - 7,708,070 (-)NCBI
Rnor_6.0710,412,577 - 10,436,936 (-)NCBI
Sequence:
RefSeq Acc Id: XR_010053045
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,328,854 - 8,358,813 (-)NCBI
RefSeq Acc Id: XR_010053046
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,328,854 - 8,358,810 (-)NCBI
RefSeq Acc Id: XR_355238
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,328,854 - 8,358,853 (-)NCBI
mRatBN7.277,685,112 - 7,708,070 (-)NCBI
Rnor_6.0710,412,577 - 10,436,936 (-)NCBI
Rnor_5.0710,568,260 - 10,607,832 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001156535 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240892 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763353 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000051405
  ENSRNOP00000051405.5
RefSeq Acc Id: NP_001156535   ⟸   NM_001163063
- UniProtKB: A0A0G2K9M2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240892   ⟸   XM_006240830
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZT66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763353   ⟸   XM_008765131
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000051405   ⟸   ENSRNOT00000047433
Ensembl Acc Id: ENSRNOP00000081680   ⟸   ENSRNOT00000094718
Ensembl Acc Id: ENSRNOP00000089425   ⟸   ENSRNOT00000104041
Ensembl Acc Id: ENSRNOP00000097778   ⟸   ENSRNOT00000101824
Ensembl Acc Id: ENSRNOP00000063560   ⟸   ENSRNOT00000063989
Ensembl Acc Id: ENSRNOP00000075050   ⟸   ENSRNOT00000086920

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9M2-F1-model_v2 AlphaFold A0A0G2K9M2 1-437 view protein structure
AF-A0A0G2QC13-F1-model_v2 AlphaFold A0A0G2QC13 1-497 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596088 AgrOrtholog
BioCyc Gene G2FUF-35061 BioCyc
Ensembl Genes ENSRNOG00000048910 Ensembl
  ENSRNOG00000066372 Ensembl
  ENSRNOG00000067221 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047433 ENTREZGENE
  ENSRNOT00000047433.5 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
NCBI Gene 690419 ENTREZGENE
PANTHER ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 544-RELATED UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
  zf-H2C2_2 UniProtKB/TrEMBL
PhenoGen Zfp709l1 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000048910 RatGTEx
  ENSRNOG00000066372 RatGTEx
  ENSRNOG00000067221 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2K9M2 ENTREZGENE
  A0A0G2QC13_RAT UniProtKB/TrEMBL
  A0A8I5ZT66 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Zfp709l1  zinc finger protein 709-like 1  LOC100909526  zinc finger protein 709-like  Data merged from RGD:6503429 737654 PROVISIONAL
2012-07-05 LOC100909526  zinc finger protein 709-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-01-21 Zfp709l1  zinc finger protein 709-like 1  LOC690419  similar to zinc finger protein 709  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC690419  similar to zinc finger protein 709      Symbol and Name status set to provisional 70820 PROVISIONAL