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Gene: Tmem116 (transmembrane protein 116) Rattus norvegicus

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Symbol:

Tmem116

Name:

transmembrane protein 116

RGD ID:

1596066

Description:

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Orthologous to human TMEM116 (transmembrane protein 116); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical protein LOC690442; hypothetical protein LOC690455; LOC690442; LOC690455

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM116 (transmembrane protein 116)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Tmem116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tmem116 (transmembrane protein 116)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TMEM116 (transmembrane protein 116)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tmem116 (transmembrane protein 116)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-157p22.10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GPR1	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	tmem116	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tmem116	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	40,681,346 - 40,750,106 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	40,702,258 - 40,750,140 (-)	Ensembl				GRCr8
mRatBN7.2	12	35,021,912 - 35,089,409 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	35,041,572 - 35,089,430 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	36,214,382 - 36,247,420 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	36,825,591 - 36,858,627 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	35,878,040 - 35,911,076 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	40,537,261 - 40,618,805 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	40,557,677 - 40,590,361 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	42,403,957 - 42,485,861 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	36,176,676 - 36,209,989 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	36,705,977 - 36,739,335 (-)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3-methylcholanthrene (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

calyculin A (ISO)

carbon nanotube (ISO)

clotrimazole (EXP)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

diethylstilbestrol (EXP)

diuron (ISO)

doxorubicin (ISO)

endosulfan (EXP)

Erionite (ISO)

fenvalerate (EXP)

folic acid (ISO)

furan (EXP)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

nickel atom (ISO)

nobiletin (EXP,ISO)

okadaic acid (ISO)

p-toluidine (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

quinolin-8-ol (ISO)

rac-lactic acid (ISO)

sulforaphane (ISO)

sunitinib (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

Triptolide (ISO)

triptonide (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (IBA)

biological_process (ND)

signal transduction (IEA)

Cellular Component

endoplasmic reticulum membrane (ISO)

membrane (IEA)

plasma membrane (IBA)

Molecular Function

G protein-coupled receptor activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Tmem116
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	40,681,346 - 40,750,106 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	40,702,258 - 40,750,140 (-)	Ensembl				GRCr8
mRatBN7.2	12	35,021,912 - 35,089,409 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	35,041,572 - 35,089,430 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	36,214,382 - 36,247,420 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	36,825,591 - 36,858,627 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	35,878,040 - 35,911,076 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	40,537,261 - 40,618,805 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	40,557,677 - 40,590,361 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	42,403,957 - 42,485,861 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	36,176,676 - 36,209,989 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	36,705,977 - 36,739,335 (-)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

TMEM116
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	111,931,282 - 112,013,219 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	111,930,181 - 112,013,908 (-)	Ensembl			hg38	GRCh38
GRCh37	12	112,369,086 - 112,451,023 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	110,853,486 - 110,935,318 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	111,994,553 - 112,076,493 (-)	NCBI		Celera
Cytogenetic Map	12	q24.13	NCBI
HuRef	12	109,382,372 - 109,464,309 (-)	NCBI		HuRef
CHM1_1	12	112,336,986 - 112,419,272 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	111,908,187 - 111,990,124 (-)	NCBI		T2T-CHM13v2.0

Tmem116
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	121,590,643 - 121,656,601 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	121,589,956 - 121,662,246 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	121,452,580 - 121,518,188 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	121,451,893 - 121,524,183 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	121,902,718 - 121,945,430 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	121,723,818 - 121,756,038 (+)	NCBI		MGSCv36	mm8
Celera	5	118,542,581 - 118,585,505 (+)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	61.81	NCBI

Tmem116
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	8,429,543 - 8,542,216 (-)	Ensembl
ChiLan1.0	NW_004955482	8,388,446 - 8,572,160 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM116
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	120,022,759 - 120,104,480 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	120,019,150 - 120,100,782 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	109,490,385 - 109,610,574 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	112,923,729 - 113,004,037 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	112,923,729 - 113,004,037 (-)	Ensembl			panPan2	panpan1.1

TMEM116
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	9,495,011 - 9,609,819 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	9,495,135 - 9,584,460 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	9,613,631 - 9,727,103 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	9,732,501 - 9,846,235 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	9,680,060 - 9,822,692 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	9,709,923 - 9,823,318 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	9,772,916 - 9,886,729 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	9,819,909 - 9,933,626 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tmem116
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	154,948,123 - 154,985,166 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936558	4,494,032 - 4,530,300 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936558	4,494,340 - 4,531,295 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM116
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	39,695,516 - 39,806,773 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	39,695,739 - 39,812,613 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	42,187,491 - 42,293,211 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM116
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	107,192,723 - 107,244,291 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	107,194,412 - 107,228,392 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	137,844,516 - 137,894,670 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem116
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	20,190,479 - 20,300,535 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	20,175,061 - 20,383,459 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tmem116
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	32,311,406 - 32,357,642 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tmem116
351 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	160
Count of miRNA genes:	128
Interacting mature miRNAs:	136
Transcripts:	ENSRNOT00000067503
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	29775522	42298555	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
631829	Alc6	Alcohol consumption QTL 6	4.7		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	34243475	43352593	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat

Markers in Region

BF403047

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	35,041,671 - 35,041,820 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	40,557,777 - 40,557,925	NCBI	Rnor6.0
Rnor_5.0	12	42,425,013 - 42,425,161	UniSTS	Rnor5.0
RGSC_v3.4	12	36,176,777 - 36,176,925	UniSTS	RGSC3.4
Celera	12	36,706,078 - 36,706,226	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	64	149	90	89	58	71	58	6	329	166	9	130	81	91	31	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001159625	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271692	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC167104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000067503 ⟹ ENSRNOP00000063208

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,702,258 - 40,735,332 (-)	Ensembl
mRatBN7.2 Ensembl	12	35,041,572 - 35,074,677 (-)	Ensembl
Rnor_6.0 Ensembl	12	40,557,677 - 40,590,361 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104465 ⟹ ENSRNOP00000081376

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,702,258 - 40,750,140 (-)	Ensembl
mRatBN7.2 Ensembl	12	35,041,572 - 35,089,430 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114714 ⟹ ENSRNOP00000092876

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,702,258 - 40,735,332 (-)	Ensembl
mRatBN7.2 Ensembl	12	35,041,572 - 35,074,677 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000154771 ⟹ ENSRNOP00000109767

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,702,258 - 40,745,123 (-)	Ensembl

RefSeq Acc Id:

NM_001159625 ⟹ NP_001153097

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,257 - 40,735,233 (-)	NCBI
mRatBN7.2	12	35,041,571 - 35,074,574 (-)	NCBI
Rnor_6.0	12	40,557,676 - 40,590,361 (-)	NCBI
Rnor_5.0	12	42,403,957 - 42,485,861 (-)	NCBI
RGSC_v3.4	12	36,176,676 - 36,209,989 (-)	RGD
Celera	12	36,705,977 - 36,739,335 (-)	RGD

Sequence:

show sequence

CTGAAGTCTGCATGGCCCTCCCACTGGAGCTTTTTCCTGCGATACAGTGGATACAGTTTGCCGT
GGCTACTCTGAGTGTTATAGGTTCCAGTTCACTTATCACCTACATCGTGTTCCAGAACCCACAG
AAGTCTGCAGAGGTAAAGTCACTCTTGTATCTGAGCTTCTCTGACCTGCTCCTGGGAATTTGCT
GGCTCATAAAGGCACTTGTCTATGGAACCGCAGCAGCCCACAAGGACAGCATCTGCTATAACCT
ACAGACTGCAGGAGAGATTTTCTACCTGGCCTCACTCGTCTTCACCGTCAGTTACATCTGGTGT
CTGTACGCGGAGCTGAGGAGGAAGCACAGCCCGAGCGAGCAGAGCACAGCTGCGCAGGTGACAG
ATTACGCTTGCCAAGGTGGTTGTGTAATGTTCCTTTTGTCAAGCCTGACACCTCTGCTGTTGAT
GACGCCTGTGTTCTTTCTGGGCAACGTCAATGAATGTTTCCACAACTTCAGCCAGAACCACAGG
TGTATGCTAATGCACTCTGAGCCACTGCCCTCCACCAACACGTCTGTCTGCAGCACACTCTATC
TTTATGGTGTCACCGTTTTCCTGGCCAGCTTTTTCTTCAGCCTCCTCACCATTGTGGTCTTACT
CGTCCTCGCCCAGACGTTATATAAGAAGTTTGTGAAATCCATGGGCCTTCTGGAGAGCGAGCAG
TGGGCAGTGATCCACACGGTGGGTCAGCGAGTGCGTTTTTTCCCAGCGGCCTTTGTGTGCTGCT
GGGGCCCAGCTGTCACACTGCTGATCATGAAGCTGACCAAGCCGCAGGAGACCTCCCTGCACGT
GGCCCTCTCTGTGCTCCAGGCTCTTACAGCAGCATCCCAGGGGCTGCTCAACTGTGGCATTTAT
GGCTGGACACAGTGCAAGTTCCAGCAGATAAAGCGCGAGCCTCCCCGTGACGCAGACACTCAGA
CCCCACTGCTGTGCTCACAGAAGAGAGTTTATAGCAGGAGCCCGAGCGCATCGAGGCCTCCTCT
TGCCTTTGCTTCCAGCTCTTCCACCGTTCTTTGAGCCTCTGGACTGCACCGTCAGGGAGTGAAT
GTGTCCCAGGAGTGGACTCTCTGCTGGCCACACCCCAGACTGATGGCCACACCCCAGACTGAAG
AGCTGAAAGGAAATGTAGGGCCATGGCCAGTAGCAATTGTGGGCGAATTCGGAAGGAACTCTCC
AACTGCTCGTTCAGGGAGATATAGCCGCTTTCTATCTAAGAGACTCATTACTTTAACAAGTACT
AGACTTATTTACATCTCTTGAAGAAAAAATAAATGTCAGGTTCATATGTAAAAAAAAAAAAAAA
AAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006249404 ⟹ XP_006249466

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,247 - 40,750,043 (-)	NCBI
mRatBN7.2	12	35,041,561 - 35,075,694 (-)	NCBI
Rnor_6.0	12	40,557,666 - 40,590,641 (-)	NCBI
Rnor_5.0	12	42,403,957 - 42,485,861 (-)	NCBI

Sequence:

show sequence

ATCAGGTCTGCTGGATTAGGCACATCCTCTCTCACTGAGGCAGCCCTCTGCTCTGTGACATCTG
TGCTGGGGGCCTCGGTCCAGCCAGCTATGCCCTTTGTTACAACTTGCTTTCTTCTGTCACCTGC
TTCTTCTATTTTTGGCTTTGTCCTTGGCCCTTCAGCCTCCTTCCCTTAAGGTACAGGGCAGGAT
TAGCTGGGGTGGAGCCCAGCTGAGGTAGGGTGGAGCTACCTGTTCCGAGCCTGACTGAGAAGGG
CCTGGGCTTGGAGGGTCGCTGGAACTGAAGTCTGCATGGCCCTCCCACTGGAGGTCAGCCGCCT
GGAAGGCAGATGGGAGTCTCTTTTTCCTGCGATACAGTGGATACAGTTTGCCGTGGCTACTCTG
AGTGTTATAGGTTCCAGTTCACTTATCACCTACATCGTGTTCCAGAACCCACAGAAGTCTGCAG
AGGTAAAGTCACTCTTGTATCTGAGCTTCTCTGACCTGCTCCTGGGAATTTGCTGGCTCATAAA
GGCACTTGTCTATGGAACCGCAGCAGCCCACAAGGACAGCATCTGCTATAACCTACAGACTGCA
GGAGAGATTTTCTACCTGGCCTCACTCGTCTTCACCGTCAGTTACATCTGGTGTCTGTACGCGG
AGCTGAGGAGGAAGCACAGCCCGAGCGAGCAGAGCACAGCTGCGCAGGTGACAGATTACGCTTG
CCAAGGTGGTTGTGTAATGTTCCTTTTGTCAAGCCTGACACCTCTGCTGTTGATGACGCCTGTG
TTCTTTCTGGGCAACGTCAATGAATGTTTCCACAACTTCAGCCAGAACCACAGGTGTATGCTAA
TGCACTCTGAGCCACTGCCCTCCACCAACACGTCTGTCTGCAGCACACTCTATCTTTATGGTGT
CACCGTTTTCCTGGCCAGCTTTTTCTTCAGCCTCCTCACCATTGTGGTCTTACTCGTCCTCGCC
CAGACGTTATATAAGAAGTTTGTGAAATCCATGGGCCTTCTGGAGAGCGAGCAGTGGGCAGTGA
TCCACACGGTGGGTCAGCGAGTGCGTTTTTTCCCAGCGGCCTTTGTGTGCTGCTGGGGCCCAGC
TGTCACACTGCTGATCATGAAGCTGACCAAGCCGCAGGAGACCTCCCTGCACGTGGCCCTCTCT
GTGCTCCAGGCTCTTACAGCAGCATCCCAGGGGCTGCTCAACTGTGGCATTTATGGCTGGACAC
AGTGCAAGTTCCAGCAGATAAAGCGCGAGCCTCCCCGTGACGCAGACACTCAGACCCCACTGCT
GTGCTCACAGAAGAGAGTTTATAGCAGGAGCCCGAGCGCATCGAGGCCTCCTCTTGCCTTTGCT
TCCAGCTCTTCCACCGTTCTTTGAGCCTCTGGACTGCACCGTCAGGGAGTGAATGTGTCCCAGG
AGTGGACTCTCTGCTGGCCACACCCCAGACTGATGGCCACACCCCAGACTGAAGAGCTGAAAGG
AAATGTAGGGCCATGGCCAGTAGCAATTGTGGGCGAATTCGGAAGGAACTCTCCAACTGCTCGT
TCAGGGAGATATAGCCGCTTTCTATCTAAGAGACTCATTACTTTAACAAGTACTAGACTTATTT
ACATCTCTTGAAGAAAAAATAAATGTCAGGTTCATATGTATGTGTGTCAA

hide sequence

RefSeq Acc Id:

XM_006249406 ⟹ XP_006249468

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,247 - 40,750,043 (-)	NCBI
mRatBN7.2	12	35,041,561 - 35,075,982 (-)	NCBI
Rnor_6.0	12	40,557,666 - 40,590,648 (-)	NCBI
Rnor_5.0	12	42,403,957 - 42,485,861 (-)	NCBI

Sequence:

show sequence

CTGGTACATCAGGTCTGCTGGATTAGGCACATCCTCTCTCACTGAGGCAGCCCTCTGCTCTGTG
ACATCTGTGCTGGGGGCCTCGGTCCAGCCAGCTATGCCCTTTGTTACAACTTGCTTTCTTCTGT
CACCTGCTTCTTCTATTTTTGGCTTTGTCCTTGGCCCTTCAGCCTCCTTCCCTTAAGGTACAGG
GCAGGATTAGCTGGGGTGGAGCCCAGCTGAGGTAGGGTGGAGCTACCTGTTCCGAGCCTGACTG
AGAAGGGCCTGGGCTTGGAGGGTCGCTGGAACTGAAGTCTGCATGGCCCTCCCACTGGAGGTCA
GCCGCCTGGAAGGCAGATGGGAGTCTCTTTTTCCTGCGATACAGTGGATACAGTTTGCCGTGGC
TACTCTGAGTGTTATAGGTTCCAGTTCACTTATCACCTACATCGTGTTCCAGAACCCACAGAAG
TCTGCAGAGGTAAAGTCACTCTTGTATCTGAGCTTCTCTGACCTGCTCCTGGGAATTTGCTGGC
TCATAAAGGCACTTGTCTATGGAACCGCAGCAGCCCACAAGGACAGCATCTGCTATAACCTACA
GACTGCAGGAGAGGTGACAGATTACGCTTGCCAAGGTGGTTGTGTAATGTTCCTTTTGTCAAGC
CTGACACCTCTGCTGTTGATGACGCCTGTGTTCTTTCTGGGCAACGTCAATGAATGTTTCCACA
ACTTCAGCCAGAACCACAGGTGTATGCTAATGCACTCTGAGCCACTGCCCTCCACCAACACGTC
TGTCTGCAGCACACTCTATCTTTATGGTGTCACCGTTTTCCTGGCCAGCTTTTTCTTCAGCCTC
CTCACCATTGTGGTCTTACTCGTCCTCGCCCAGACGTTATATAAGAAGTTTGTGAAATCCATGG
GCCTTCTGGAGAGCGAGCAGTGGGCAGTGATCCACACGGTGGGTCAGCGAGTGCGTTTTTTCCC
AGCGGCCTTTGTGTGCTGCTGGGGCCCAGCTGTCACACTGCTGATCATGAAGCTGACCAAGCCG
CAGGAGACCTCCCTGCACGTGGCCCTCTCTGTGCTCCAGGCTCTTACAGCAGCATCCCAGGGGC
TGCTCAACTGTGGCATTTATGGCTGGACACAGTGCAAGTTCCAGCAGATAAAGCGCGAGCCTCC
CCGTGACGCAGACACTCAGACCCCACTGCTGTGCTCACAGAAGAGAGTTTATAGCAGGAGCCCG
AGCGCATCGAGGCCTCCTCTTGCCTTTGCTTCCAGCTCTTCCACCGTTCTTTGAGCCTCTGGAC
TGCACCGTCAGGGAGTGAATGTGTCCCAGGAGTGGACTCTCTGCTGGCCACACCCCAGACTGAT
GGCCACACCCCAGACTGAAGAGCTGAAAGGAAATGTAGGGCCATGGCCAGTAGCAATTGTGGGC
GAATTCGGAAGGAACTCTCCAACTGCTCGTTCAGGGAGATATAGCCGCTTTCTATCTAAGAGAC
TCATTACTTTAACAAGTACTAGACTTATTTACATCTCTTGAAGAAAAAATAAATGTCAGGTTCA
TATGTATGTGTGTCAA

hide sequence

RefSeq Acc Id:

XM_017598460 ⟹ XP_017453949

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,043 (-)	NCBI
mRatBN7.2	12	35,021,912 - 35,075,694 (-)	NCBI
Rnor_6.0	12	40,537,261 - 40,590,578 (-)	NCBI

Sequence:

show sequence

GTGCTGGGGGCCTCGGTCCAGCCAGCTATGCCCTTTGTTACAACTTGCTTTCTTCTGTCACCTG
CTTCTTCTATTTTTGGCTTTGTCCTTGGCCCTTCAGCCTCCTTCCCTTAAGGTACAGGGCAGGA
TTAGCTGGGGTGGAGCCCAGCTGAGGTAGGGTGGAGCTACCTGTTCCGAGCCTGACTGAGAAGG
GCCTGGGCTTGGAGGGTCGCTGGAACTGAAGTCTGCATGGCCCTCCCACTGGAGGTCAGCCGCC
TGGAAGGCAGATGGGAGTCTCTTTTTCCTGCGATACAGTGGATACAGTTTGCCGTGGCTACTCT
GAGTGTTATAGGTTCCAGTTCACTTATCACCTACATCGTGTTCCAGAACCCACAGAAGTCTGCA
GAGGTAAAGTCACTCTTGTATCTGAGCTTCTCTGACCTGCTCCTGGGAATTTGCTGGCTCATAA
AGGCACTTGTCTATGGAACCGCAGCAGCCCACAAGGACAGCATCTGCTATAACCTACAGACTGC
AGGAGAGATTTTCTACCTGGCCTCACTCGTCTTCACCGTCAGTTACATCTGGTGTCTGTACGCG
GAGCTGAGGAGGAAGCACAGCCCGAGCGAGCAGAGCACAGCTGCGCAGGTGACAGATTACGCTT
GCCAAGGTGGTTGTGTAATGTTCCTTTTGTCAAGCCTGACACCTCTGCTGTTGATGACGCCTGT
GTTCTTTCTGGGCAACGTCAATGAATGTTTCCACAACTTCAGCCAGAACCACAGGTGTATGCTA
ATGCACTCTGAGCCACTGCCCTCCACCAACACGTCTGTCTGCAGCACACTCTATCTTTATGGTG
TCACCGTTTTCCTGGCCAGCTTTTTCTTCAGCCTCCTCACCATTGTGGTCTTACTCGTCCTCGC
CCAGACGTTATATAAGAAGTTTGTGAAATCCATGGGCCTTCTGGAGAGCGAGCAGTGGGCAGTG
ATCCACACGGTGGGTCAGCGAGTGCGTTTTTTCCCAGCGGCCTTTGTGTGCTGCTGGGGCCCAG
CTGTCACACTGCTGATCATGAAGCTGACCAAGCCGCAGGAGACCTCCCTGCACGTGGCCCTCTC
TGTGCTCCAGAATAATGGTCCCCCACAGTGGATACTGTGACATCTTCCCAGAATCTTCCTCATG
CCAGCAACATGGACACGGATGTCCCTCCTCTAGCCACACAGCATTAATCAGCCCCAGAGCTCTC
AAAACACATGACTAGCTAGCCTGTCTGCTGACTGCAGACCCGGTCACCTTGCTGCCTAGTGAAC
ACAGCCACTTAACAGGCATCTCAGCCTGAACCCAGCCATGTCTGCTAGCCACACTTGGCCCATC
CCAGTTGAAGACCAGCCAGTGAGTGCACGTCTGAGTTCTGCTGCACTCTCTGTGACCCCTCTGT
GGGCAAATCCTTTTAGCTTTCGGGGGTGTTGTCATATCTCAAGGGATGACAGTGTTCCTAGAGC
TTCTCAACTTCCTAATGCTGTGACCTGGAAGGTGGTTTTCCAAGTTGCTTTCATTCCTATTTCA
TACCTATAACTTTGCTGCAGTTATGAATTACAATGTAAATGTGTGATGTGCAGAGGGGCTTAGG
AGACCCCTATGAAAGGCAGCTGTAGGCCGAGGTTGAGAACCACCGCTAAGACCTAGATCCTACT
GTAAGATCCGTCACGCTCAACACCAGCATCATCCTCTACTTGGCAAAGCAAAGCAAGAGCAGAT
AACGTTCTGTAACTACACGATGAATTGCACATTTATTTTATTTTTCTGAGACAAGACAGGTTTG
TTTGTGTAATTTTGGCTGTCCTGAAACTGACAGAAATGTAGTTCTCTACATAGACCAGGATGGC
CTTGAACTCACCTGCCTCAGCCTCCAAGTGCAGGCTTATGAGCCACCACCAACCTGCTGAATTG
CACACTTTTATCCTAAGGTGTTATTCTGTAGTCCAGGCTGGCCACTGACTGGTGCCAGTACTCC
TGCCTTAGTCTCCCTAGGTGGAGATCACAGGCATGAGACGCCATATTTGACTGGGAACTAGATC
TAGGGCATTGCATGTGCTAGGTAAGAACAGCACCACTGTTCTCTATTCACAGCTAATGGGTTAG
TTTCAAGATGCTTTTAAAATGATCAGATGGTGCAGGGGGTTCTTGCTACATCTCAGTATCTAAT
TAAGGACTGATCGGGACAGTCAGACTCATCAAATGTTCTTCCTTTTTACTGAAGGGAGGGAAAG
GCGCAGTGACAGTGTAGGCTGTGGGGTGGGGTACCCGCCACAGGCTCTTCCTGCCTGTCTCTGA
GGAGAGGTATTAAACCTGTCACACAGAAGGAA

hide sequence

RefSeq Acc Id:

XM_039089786 ⟹ XP_038945714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,247 - 40,750,091 (-)	NCBI
mRatBN7.2	12	35,041,561 - 35,089,409 (-)	NCBI

RefSeq Acc Id:

XM_039089787 ⟹ XP_038945715

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,043 (-)	NCBI
mRatBN7.2	12	35,021,912 - 35,075,693 (-)	NCBI

RefSeq Acc Id:

XM_063271683 ⟹ XP_063127753

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,247 - 40,750,057 (-)	NCBI

RefSeq Acc Id:

XM_063271684 ⟹ XP_063127754

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,247 - 40,750,065 (-)	NCBI

RefSeq Acc Id:

XM_063271685 ⟹ XP_063127755

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,247 - 40,750,066 (-)	NCBI

RefSeq Acc Id:

XM_063271686 ⟹ XP_063127756

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,043 (-)	NCBI

RefSeq Acc Id:

XM_063271687 ⟹ XP_063127757

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,080 (-)	NCBI

RefSeq Acc Id:

XM_063271689 ⟹ XP_063127759

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,043 (-)	NCBI

RefSeq Acc Id:

XM_063271690 ⟹ XP_063127760

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,247 - 40,750,039 (-)	NCBI

RefSeq Acc Id:

XM_063271691 ⟹ XP_063127761

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,065 (-)	NCBI

RefSeq Acc Id:

XM_063271692 ⟹ XP_063127762

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,074 (-)	NCBI

RefSeq Acc Id:

XM_063271693 ⟹ XP_063127763

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,106 (-)	NCBI

RefSeq Acc Id:

XM_063271694 ⟹ XP_063127764

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,100 (-)	NCBI

RefSeq Acc Id:

XR_005491674

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,702,661 - 40,750,043 (-)	NCBI
mRatBN7.2	12	35,041,916 - 35,075,693 (-)	NCBI

RefSeq Acc Id:

XR_005491675

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,681,346 - 40,750,043 (-)	NCBI
mRatBN7.2	12	35,021,912 - 35,075,693 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001153097	(Get FASTA)	NCBI Sequence Viewer
	XP_006249466	(Get FASTA)	NCBI Sequence Viewer
	XP_006249468	(Get FASTA)	NCBI Sequence Viewer
	XP_017453949	(Get FASTA)	NCBI Sequence Viewer
	XP_038945714	(Get FASTA)	NCBI Sequence Viewer
	XP_038945715	(Get FASTA)	NCBI Sequence Viewer
	XP_063127753	(Get FASTA)	NCBI Sequence Viewer
	XP_063127754	(Get FASTA)	NCBI Sequence Viewer
	XP_063127755	(Get FASTA)	NCBI Sequence Viewer
	XP_063127756	(Get FASTA)	NCBI Sequence Viewer
	XP_063127757	(Get FASTA)	NCBI Sequence Viewer
	XP_063127759	(Get FASTA)	NCBI Sequence Viewer
	XP_063127760	(Get FASTA)	NCBI Sequence Viewer
	XP_063127761	(Get FASTA)	NCBI Sequence Viewer
	XP_063127762	(Get FASTA)	NCBI Sequence Viewer
	XP_063127763	(Get FASTA)	NCBI Sequence Viewer
	XP_063127764	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI67104	(Get FASTA)	NCBI Sequence Viewer
	EDM13733	(Get FASTA)	NCBI Sequence Viewer
	EDM13734	(Get FASTA)	NCBI Sequence Viewer
	EDM13735	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000063208
	ENSRNOP00000063208.3
	ENSRNOP00000081376
	ENSRNOP00000081376.1
	ENSRNOP00000092876
	ENSRNOP00000092876.1
	ENSRNOP00000109767
	ENSRNOP00000109767.1

RefSeq Acc Id:

NP_001153097 ⟸ NM_001159625

- UniProtKB:

B2RZC5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALPLELFPAIQWIQFAVATLSVIGSSSLITYIVFQNPQKSAEVKSLLYLSFSDLLLGICWLIK
ALVYGTAAAHKDSICYNLQTAGEIFYLASLVFTVSYIWCLYAELRRKHSPSEQSTAAQVTDYAC
QGGCVMFLLSSLTPLLLMTPVFFLGNVNECFHNFSQNHRCMLMHSEPLPSTNTSVCSTLYLYGV
TVFLASFFFSLLTIVVLLVLAQTLYKKFVKSMGLLESEQWAVIHTVGQRVRFFPAAFVCCWGPA
VTLLIMKLTKPQETSLHVALSVLQALTAASQGLLNCGIYGWTQCKFQQIKREPPRDADTQTPLL
CSQKRVYSRSPSASRPPLAFASSSSTVL

hide sequence

RefSeq Acc Id:	XP_006249468 ⟸ XM_006249406
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6AEQ5 (UniProtKB/TrEMBL), A6J1E5 (UniProtKB/TrEMBL), B2RZC5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALPLEVSRLEGRWESLFPAIQWIQFAVATLSVIGSSSLITYIVFQNPQKSAEVKSLLYLSFSD LLLGICWLIKALVYGTAAAHKDSICYNLQTAGEVTDYACQGGCVMFLLSSLTPLLLMTPVFFLG NVNECFHNFSQNHRCMLMHSEPLPSTNTSVCSTLYLYGVTVFLASFFFSLLTIVVLLVLAQTLY KKFVKSMGLLESEQWAVIHTVGQRVRFFPAAFVCCWGPAVTLLIMKLTKPQETSLHVALSVLQA LTAASQGLLNCGIYGWTQCKFQQIKREPPRDADTQTPLLCSQKRVYSRSPSASRPPLAFASSSS TVL hide sequence

RefSeq Acc Id:	XP_006249466 ⟸ XM_006249404
- Peptide Label:	isoform X1
- UniProtKB:	F1LRF5 (UniProtKB/TrEMBL), A6J1E6 (UniProtKB/TrEMBL), B2RZC5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALPLEVSRLEGRWESLFPAIQWIQFAVATLSVIGSSSLITYIVFQNPQKSAEVKSLLYLSFSD LLLGICWLIKALVYGTAAAHKDSICYNLQTAGEIFYLASLVFTVSYIWCLYAELRRKHSPSEQS TAAQVTDYACQGGCVMFLLSSLTPLLLMTPVFFLGNVNECFHNFSQNHRCMLMHSEPLPSTNTS VCSTLYLYGVTVFLASFFFSLLTIVVLLVLAQTLYKKFVKSMGLLESEQWAVIHTVGQRVRFFP AAFVCCWGPAVTLLIMKLTKPQETSLHVALSVLQALTAASQGLLNCGIYGWTQCKFQQIKREPP RDADTQTPLLCSQKRVYSRSPSASRPPLAFASSSSTVL hide sequence

RefSeq Acc Id:

XP_017453949 ⟸ XM_017598460

- Peptide Label:

isoform X6

- Sequence:

show sequence

MALPLEVSRLEGRWESLFPAIQWIQFAVATLSVIGSSSLITYIVFQNPQKSAEVKSLLYLSFSD
LLLGICWLIKALVYGTAAAHKDSICYNLQTAGEIFYLASLVFTVSYIWCLYAELRRKHSPSEQS
TAAQVTDYACQGGCVMFLLSSLTPLLLMTPVFFLGNVNECFHNFSQNHRCMLMHSEPLPSTNTS
VCSTLYLYGVTVFLASFFFSLLTIVVLLVLAQTLYKKFVKSMGLLESEQWAVIHTVGQRVRFFP
AAFVCCWGPAVTLLIMKLTKPQETSLHVALSVLQNNGPPQWIL

hide sequence

Ensembl Acc Id:

ENSRNOP00000063208 ⟸ ENSRNOT00000067503

RefSeq Acc Id:	XP_038945715 ⟸ XM_039089787
- Peptide Label:	isoform X10

RefSeq Acc Id:	XP_038945714 ⟸ XM_039089786
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZRI1 (UniProtKB/TrEMBL), B2RZC5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000081376 ⟸ ENSRNOT00000104465

Ensembl Acc Id:

ENSRNOP00000092876 ⟸ ENSRNOT00000114714

RefSeq Acc Id:	XP_063127763 ⟸ XM_063271693
- Peptide Label:	isoform X15

RefSeq Acc Id:	XP_063127764 ⟸ XM_063271694
- Peptide Label:	isoform X16

RefSeq Acc Id:	XP_063127757 ⟸ XM_063271687
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_063127762 ⟸ XM_063271692
- Peptide Label:	isoform X14

RefSeq Acc Id:	XP_063127761 ⟸ XM_063271691
- Peptide Label:	isoform X13

RefSeq Acc Id:	XP_063127759 ⟸ XM_063271689
- Peptide Label:	isoform X11

RefSeq Acc Id:	XP_063127756 ⟸ XM_063271686
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_063127755 ⟸ XM_063271685
- Peptide Label:	isoform X7
- UniProtKB:	B2RZC5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127754 ⟸ XM_063271684
- Peptide Label:	isoform X5
- UniProtKB:	B2RZC5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127753 ⟸ XM_063271683
- Peptide Label:	isoform X3
- UniProtKB:	B2RZC5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127760 ⟸ XM_063271690
- Peptide Label:	isoform X12
- UniProtKB:	A6J1E7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000109767 ⟸ ENSRNOT00000154771

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LRF5-F1-model_v2	AlphaFold	F1LRF5	1-348	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1596066	AgrOrtholog
BioCyc Gene	G2FUF-19213	BioCyc
Ensembl Genes	ENSRNOG00000027480	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000067503	ENTREZGENE
	ENSRNOT00000067503.4	UniProtKB/TrEMBL
	ENSRNOT00000104465	ENTREZGENE
	ENSRNOT00000104465.2	UniProtKB/TrEMBL
	ENSRNOT00000114714	ENTREZGENE
	ENSRNOT00000114714.2	UniProtKB/TrEMBL
	ENSRNOT00000154771	ENTREZGENE
	ENSRNOT00000154771.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
KEGG Report	rno:690442	UniProtKB/TrEMBL
NCBI Gene	690442	ENTREZGENE
PANTHER	G PROTEIN-COUPLED RECEPTOR 157-RELATED	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 116	UniProtKB/TrEMBL
PhenoGen	Tmem116	PhenoGen
RatGTEx	ENSRNOG00000027480	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8I5ZRI1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AEQ5	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LUC5_RAT	UniProtKB/TrEMBL
	A6J1E5	ENTREZGENE, UniProtKB/TrEMBL
	A6J1E6	ENTREZGENE, UniProtKB/TrEMBL
	A6J1E7	ENTREZGENE, UniProtKB/TrEMBL
	B2RZC5	ENTREZGENE, UniProtKB/TrEMBL
	F1LRF5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-06-15	Tmem116	transmembrane protein 116	LOC690455	hypothetical protein LOC690455	Data merged from RGD:1596053	737654	PROVISIONAL
2009-06-15	Tmem116	transmembrane protein 116	LOC687361	hypothetical protein LOC687361	Data merged from RGD:1586536	1643240	APPROVED
2008-03-06	Tmem116	transmembrane protein 116	LOC690442	hypothetical protein LOC690442	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC690442	hypothetical protein LOC690442			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC690455	hypothetical protein LOC690455			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC687361	hypothetical protein LOC687361			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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