Rnf148 (ring finger protein 148) - Rat Genome Database

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Pathways
Gene: Rnf148 (ring finger protein 148) Rattus norvegicus
Analyze
Symbol: Rnf148
Name: ring finger protein 148
RGD ID: 1595417
Description: Orthologous to human RNF148 (ring finger protein 148); INTERACTS WITH 17beta-estradiol; bisphenol A; 17beta-hydroxy-5alpha-androstan-3-one (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC681407; ring finger protein 148-like; similar to ring finger protein 148
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8453,111,416 - 53,118,125 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2452,145,798 - 52,152,508 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx457,125,862 - 57,132,587 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0453,046,890 - 53,053,616 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0451,475,891 - 51,482,618 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0450,687,159 - 50,693,869 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl450,687,311 - 50,693,869 (-)Ensemblrn6Rnor6.0
Rnor_5.0450,467,597 - 50,474,307 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4450,029,841 - 50,036,551 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera447,337,224 - 47,344,120 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Rnf148
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8453,111,416 - 53,118,125 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2452,145,798 - 52,152,508 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx457,125,862 - 57,132,587 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0453,046,890 - 53,053,616 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0451,475,891 - 51,482,618 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0450,687,159 - 50,693,869 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl450,687,311 - 50,693,869 (-)Ensemblrn6Rnor6.0
Rnor_5.0450,467,597 - 50,474,307 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4450,029,841 - 50,036,551 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera447,337,224 - 47,344,120 (-)NCBICelera
Cytogenetic Map4q22NCBI
RNF148
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387122,701,668 - 122,702,922 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7122,701,668 - 122,702,922 (-)Ensemblhg38GRCh38
GRCh377122,341,722 - 122,342,976 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367122,128,956 - 122,130,257 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347121,935,670 - 121,936,972NCBI
Celera7117,146,021 - 117,147,322 (-)NCBICelera
Cytogenetic Map7q31.32NCBI
HuRef7116,704,606 - 116,705,907 (-)NCBIHuRef
CHM1_17122,275,021 - 122,276,322 (-)NCBICHM1_1
T2T-CHM13v2.07124,013,712 - 124,021,414 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27121,736,421 - 121,737,722 (-)NCBI
Rnf148
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39623,653,894 - 23,655,135 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl623,653,897 - 23,655,135 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38623,653,895 - 23,655,136 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl623,653,898 - 23,655,136 (-)Ensemblmm10GRCm38
MGSCv37623,603,895 - 23,605,136 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36623,603,898 - 23,605,138 (-)NCBIMGSCv36mm8
Celera623,676,984 - 23,678,225 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map611.01NCBI
Rnf148
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554794,322,099 - 4,323,349 (-)NCBIChiLan1.0ChiLan1.0
RNF148
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26159,572,868 - 159,573,999 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1711,583,122 - 11,584,253 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07114,711,928 - 114,713,223 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17127,395,627 - 127,396,940 (-)NCBIPanPan1.1PanPan1.1panPan2
RNF148
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11460,421,841 - 60,423,148 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1459,842,644 - 59,843,949 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01460,461,628 - 60,462,933 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11460,551,506 - 60,552,811 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01460,179,018 - 60,180,322 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01460,556,957 - 60,558,262 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rnf148
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511849,531,180 - 49,532,479 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366052,671,451 - 2,672,746 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF148
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11824,521,658 - 24,528,943 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21826,124,595 - 26,125,973 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF148
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12191,494,049 - 91,495,337 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2191,494,214 - 91,495,125 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604211,995,393 - 11,998,976 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf148
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478313,283,350 - 13,304,463 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rnf148
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16115,614,012 - 115,615,396 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rnf148
24 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:107
Count of miRNA genes:92
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000064228
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)41308014658080146Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41564430960644309Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41103870656038706Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)44049044275726188Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41103870656038706Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4589457557613242Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41103870656038706Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
10450825Scl78Serum cholesterol level QTL 783.70.01blood VLDL cholesterol amount (VT:0005144)blood low density lipoprotein cholesterol level (CMO:0000053)45014392658080146Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41890069763900697Rat
10450821Scl77Serum cholesterol level QTL 774.10.01blood VLDL cholesterol amount (VT:0005144)blood high density lipoprotein cholesterol level (CMO:0000052)45014392658080146Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43726957782269577Rat
10450818Scl76Serum cholesterol level QTL 763.60.01blood VLDL cholesterol amount (VT:0005144)blood high density lipoprotein cholesterol level (CMO:0000052)45014392658080146Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41103870656038706Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)44047145375939996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42228845363245191Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)41890069763900697Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41103870656038706Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41891315163913151Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42786220462997402Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42192515166925151Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41103870656038706Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43353881653719714Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 10 14 57 61 61 31 21 31 5 152 52 39 48 50 30 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000064228   ⟹   ENSRNOP00000059865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl450,687,311 - 50,693,869 (-)Ensembl
RefSeq Acc Id: NM_001191082   ⟹   NP_001178011
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8453,111,416 - 53,118,125 (-)NCBI
mRatBN7.2452,145,798 - 52,152,508 (-)NCBI
Rnor_6.0450,687,159 - 50,693,869 (-)NCBI
Rnor_5.0450,467,597 - 50,474,307 (-)NCBI
Celera447,337,224 - 47,344,120 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178011 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001178011   ⟸   NM_001191082
- UniProtKB: F1M1T7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000059865   ⟸   ENSRNOT00000064228

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M1T7-F1-model_v2 AlphaFold F1M1T7 1-316 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595417 AgrOrtholog
BioCyc Gene G2FUF-45494 BioCyc
Ensembl Genes ENSRNOG00000042462 Ensembl
NCBI Gene 681407 ENTREZGENE
PhenoGen Rnf148 PhenoGen
RatGTEx ENSRNOG00000042462 RatGTEx
UniProt F1M1T7 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Rnf148  ring finger protein 148  LOC100364637  ring finger protein 148-like  Data merged from RGD:2320624 1643240 APPROVED
2010-05-05 LOC100364637  ring finger protein 148-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-05 Rnf148  ring finger protein 148  LOC681407  similar to ring finger protein 148  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC681407  similar to ring finger protein 148  LOC681798  similar to ring finger protein 148  Data merged from RGD:1591608 1643240 APPROVED
2006-11-20 LOC681407  similar to ring finger protein 148      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681798  similar to ring finger protein 148      Symbol and Name status set to provisional 70820 PROVISIONAL