Ecscr (endothelial cell surface expressed chemotaxis and apoptosis regulator) - Rat Genome Database

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Pathways
Gene: Ecscr (endothelial cell surface expressed chemotaxis and apoptosis regulator) Rattus norvegicus
Analyze
Symbol: Ecscr
Name: endothelial cell surface expressed chemotaxis and apoptosis regulator
RGD ID: 1594804
Description: Predicted to be involved in negative regulation of angiogenesis; positive regulation of endothelial cell apoptotic process; and positive regulation of proteasomal protein catabolic process. Predicted to be located in membrane. Predicted to be active in cytosol and plasma membrane. Orthologous to human ECSCR (endothelial cell surface expressed chemotaxis and apoptosis regulator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: apoptosis regulator through modulating IAP expression; Aria; Ecscr-ps1; endothelial cell-specific chemotaxis regulator; endothelial cell-specific chemotaxis regulator, pseudogene 1; hypothetical protein LOC682650; hypothetical protein LOC689248; LOC689248
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,583,791 - 27,593,184 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1827,583,195 - 27,593,195 (-)EnsemblGRCr8
mRatBN7.21827,309,711 - 27,319,106 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,309,718 - 27,319,032 (-)EnsemblmRatBN7.2
Rnor_6.01828,507,167 - 28,516,567 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,506,934 - 28,516,209 (-)Ensemblrn6Rnor6.0
Rnor_5.01828,219,716 - 28,229,043 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41828,328,191 - 28,340,335 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1827,043,217 - 27,052,411 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,ISO)
plasma membrane  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19416853   PMID:24338479  


Genomics

Comparative Map Data
Ecscr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,583,791 - 27,593,184 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1827,583,195 - 27,593,195 (-)EnsemblGRCr8
mRatBN7.21827,309,711 - 27,319,106 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,309,718 - 27,319,032 (-)EnsemblmRatBN7.2
Rnor_6.01828,507,167 - 28,516,567 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,506,934 - 28,516,209 (-)Ensemblrn6Rnor6.0
Rnor_5.01828,219,716 - 28,229,043 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41828,328,191 - 28,340,335 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1827,043,217 - 27,052,411 (-)NCBICelera
Cytogenetic Map18p11NCBI
ECSCR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385139,448,560 - 139,462,743 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5139,446,541 - 139,462,745 (-)Ensemblhg38GRCh38
GRCh375138,784,249 - 138,842,328 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365138,817,313 - 138,822,504 (-)NCBIBuild 36Build 36hg18NCBI36
Celera5134,904,524 - 134,917,004 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5133,976,927 - 133,984,822 (-)NCBIHuRef
HuRef5133,973,970 - 133,974,590 (-)NCBIHuRef
CHM1_15138,216,851 - 138,217,469 (-)NCBICHM1_1
CHM1_15138,269,725 - 138,274,901 (-)NCBICHM1_1
T2T-CHM13v2.05139,974,387 - 139,987,818 (-)NCBIT2T-CHM13v2.0
Ecscr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,846,139 - 35,855,460 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1835,846,139 - 35,855,409 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381835,713,086 - 35,722,413 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1835,713,086 - 35,722,356 (-)Ensemblmm10GRCm38
MGSCv371835,872,743 - 35,881,145 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361835,839,063 - 35,847,465 (-)NCBIMGSCv36mm8
Celera1836,169,173 - 36,177,565 (-)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.22NCBI
Ecscr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554181,109,092 - 1,115,997 (+)Ensembl
ChiLan1.0NW_0049554181,108,805 - 1,116,338 (+)NCBIChiLan1.0ChiLan1.0
ECSCR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24134,715,413 - 134,730,371 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15132,854,965 - 132,870,071 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05134,819,568 - 134,833,508 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15140,940,578 - 140,955,137 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5140,940,578 - 140,955,140 (-)EnsemblpanPan2panpan1.1
ECSCR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1234,763,814 - 34,773,491 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,866,062 - 31,875,564 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0235,219,054 - 35,227,401 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,217,688 - 35,243,000 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,270,349 - 32,279,851 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,136,664 - 33,146,167 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0233,889,703 - 33,898,041 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ecscr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213153,068,890 - 153,077,585 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365318,532,353 - 8,542,551 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365318,533,926 - 8,542,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECSCR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2141,343,803 - 141,352,603 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12141,343,818 - 141,352,618 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,153,633 - 147,162,663 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ECSCR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,124,181 - 42,137,577 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2342,123,875 - 42,137,196 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603435,750,604 - 35,763,890 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ecscr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474332,246,966 - 32,256,617 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474332,248,768 - 32,272,352 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ecscr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1158,652,336 - 8,660,410 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ecscr
25 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:68
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000060689, ENSRNOT00000072580
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
2301409Cm70Cardiac mass QTL 700.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)18706572852065728Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)182201556261600538Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181564228031610627Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181221668431644508Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
12904716Am21Aortic mass QTL 210.005aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)18706572852065728Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
12904714Cm131Cardiac mass QTL 1310.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)18706572852065728Rat
12904715Cm132Cardiac mass QTL 1320.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)18706572852065728Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181522610142690662Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18546045542690191Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181221668431644508Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228031610627Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18144930869Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181206648257066482Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18381190230809809Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134566578Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18448264849482648Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18154490981Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
11565454Kidm59Kidney mass QTL 590.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)18706572852065728Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134566578Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)18430735449307354Rat

Markers in Region
D18Mit15  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81827,581,336 - 27,581,421 (+)Marker Load Pipeline
mRatBN7.21827,307,256 - 27,307,341 (+)MAPPERmRatBN7.2
Rnor_6.01828,504,713 - 28,504,797NCBIRnor6.0
Rnor_5.01828,217,262 - 28,217,346UniSTSRnor5.0
RGSC_v3.41828,329,666 - 28,329,750UniSTSRGSC3.4
RGSC_v3.41828,329,665 - 28,329,750RGDRGSC3.4
Celera1827,040,623 - 27,040,707UniSTS
RGSC_v3.11828,356,168 - 28,356,559RGD
Cytogenetic Map18p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 158 91 90 59 32 59 6 294 132 11 137 79 92 31 16 16

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001432559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC135285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000072580   ⟹   ENSRNOP00000067313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1827,583,498 - 27,593,195 (-)Ensembl
mRatBN7.2 Ensembl1827,309,765 - 27,318,822 (-)Ensembl
Rnor_6.0 Ensembl1828,506,934 - 28,516,209 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097911   ⟹   ENSRNOP00000087965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1827,584,513 - 27,593,195 (-)Ensembl
mRatBN7.2 Ensembl1827,310,432 - 27,318,747 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110568   ⟹   ENSRNOP00000088865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1827,583,195 - 27,591,912 (-)Ensembl
mRatBN7.2 Ensembl1827,309,765 - 27,317,832 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120258   ⟹   ENSRNOP00000079454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1827,583,401 - 27,592,874 (-)Ensembl
mRatBN7.2 Ensembl1827,309,718 - 27,319,032 (-)Ensembl
RefSeq Acc Id: XM_008772057   ⟹   XP_008770279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,583,791 - 27,592,878 (-)NCBI
mRatBN7.21827,309,711 - 27,318,795 (-)NCBI
Rnor_6.01828,507,167 - 28,516,564 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601091   ⟹   XP_017456580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,583,791 - 27,592,896 (-)NCBI
mRatBN7.21827,309,711 - 27,318,797 (-)NCBI
Rnor_6.01828,507,167 - 28,516,567 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601092   ⟹   XP_017456581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,583,791 - 27,592,882 (-)NCBI
mRatBN7.21827,309,711 - 27,318,796 (-)NCBI
Rnor_6.01828,507,167 - 28,516,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601093   ⟹   XP_017456582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,583,791 - 27,593,184 (-)NCBI
mRatBN7.21827,309,711 - 27,319,106 (-)NCBI
Rnor_6.01828,507,167 - 28,516,566 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097302   ⟹   XP_038953230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,584,513 - 27,593,175 (-)NCBI
mRatBN7.21827,310,432 - 27,318,798 (-)NCBI
RefSeq Acc Id: XM_063277649   ⟹   XP_063133719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,583,791 - 27,592,877 (-)NCBI
RefSeq Acc Id: XM_063277650   ⟹   XP_063133720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,583,791 - 27,593,164 (-)NCBI
RefSeq Acc Id: XP_008770279   ⟸   XM_008772057
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017456580   ⟸   XM_017601091
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A8X7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456582   ⟸   XM_017601093
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A8X7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456581   ⟸   XM_017601092
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A8X7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067313   ⟸   ENSRNOT00000072580
RefSeq Acc Id: XP_038953230   ⟸   XM_039097302
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A8X7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088865   ⟸   ENSRNOT00000110568
Ensembl Acc Id: ENSRNOP00000079454   ⟸   ENSRNOT00000120258
Ensembl Acc Id: ENSRNOP00000087965   ⟸   ENSRNOT00000097911
RefSeq Acc Id: XP_063133720   ⟸   XM_063277650
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A8X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133719   ⟸   XM_063277649
- Peptide Label: isoform X6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RCJ4-F1-model_v2 AlphaFold M0RCJ4 1-224 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700716
Promoter ID:EPDNEW_R11237
Type:initiation region
Name:Ecscr_1
Description:endothelial cell surface expressed chemotaxis and apoptosis regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01828,516,172 - 28,516,232EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594804 AgrOrtholog
BioCyc Gene G2FUF-7896 BioCyc
Ensembl Genes ENSRNOG00000039593 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072580 ENTREZGENE
  ENSRNOT00000072580.5 UniProtKB/TrEMBL
  ENSRNOT00000097911 ENTREZGENE
  ENSRNOT00000097911.2 UniProtKB/TrEMBL
  ENSRNOT00000110568.2 UniProtKB/TrEMBL
  ENSRNOT00000120258 ENTREZGENE
  ENSRNOT00000120258.2 UniProtKB/TrEMBL
InterPro ECSCR UniProtKB/TrEMBL
KEGG Report rno:689248 UniProtKB/TrEMBL
NCBI Gene 689248 ENTREZGENE
PANTHER ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR UniProtKB/TrEMBL
  PTHR28602 UniProtKB/TrEMBL
Pfam ECSCR UniProtKB/TrEMBL
PhenoGen Ecscr PhenoGen
PRINTS ECCREGULATOR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039593 RatGTEx
UniProt A0A8I6A6Y3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8X7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5C4 ENTREZGENE, UniProtKB/TrEMBL
  A6J2Z3 ENTREZGENE, UniProtKB/TrEMBL
  M0RCJ4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Ecscr  endothelial cell surface expressed chemotaxis and apoptosis regulator  LOC682650  hypothetical protein LOC682650  Data merged from RGD:1596642 1643240 APPROVED
2013-03-06 Ecscr  endothelial cell surface expressed chemotaxis and apoptosis regulator  Ecscr  endothelial cell-specific chemotaxis regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-05 Ecscr  endothelial cell-specific chemotaxis regulator  Ecscr-ps1  endothelial cell-specific chemotaxis regulator, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-06-08 Ecscr-ps1  endothelial cell-specific chemotaxis regulator, pseudogene 1  Ecscr  endothelial cell-specific chemotaxis regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Ecscr  endothelial cell-specific chemotaxis regulator  LOC689248  hypothetical protein LOC689248  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC689248  hypothetical protein LOC689248      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC682650  hypothetical protein LOC682650      Symbol and Name status set to provisional 70820 PROVISIONAL