Mpp1 (MAGUK p55 scaffold protein 1) - Rat Genome Database

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Gene: Mpp1 (MAGUK p55 scaffold protein 1) Rattus norvegicus
Analyze
Symbol: Mpp1
Name: MAGUK p55 scaffold protein 1
RGD ID: 1594331
Description: Orthologous to human MPP1 (MAGUK p55 scaffold protein 1); INTERACTS WITH finasteride; nefazodone; nimesulide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC652956; membrane palmitoylated protein 1; membrane protein, palmitoylated 1; p55; p55 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
UTH_Rnor_SHR_UtxY2,135,600 - 2,144,211 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X158,511,209 - 158,519,820 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0Y263,077 - 271,689 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01148,450,213 - 148,458,945 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01154,731,975 - 154,741,021 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1137,539,255 - 137,547,772 (+)NCBICelera
Cytogenetic Map1q31NCBI



Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-hydroxypropanoic acid  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CHIR 99021  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
finasteride  (EXP)
folic acid  (ISO)
FR900359  (ISO)
glycidyl methacrylate  (ISO)
methotrexate  (ISO)
Monobutylphthalate  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thalidomide  (ISO)
titanium dioxide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15857683   PMID:18723693   PMID:19897731   PMID:19946888   PMID:24962407  


Genomics

Comparative Map Data
Mpp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
UTH_Rnor_SHR_UtxY2,135,600 - 2,144,211 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X158,511,209 - 158,519,820 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0Y263,077 - 271,689 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01148,450,213 - 148,458,945 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01154,731,975 - 154,741,021 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1137,539,255 - 137,547,772 (+)NCBICelera
Cytogenetic Map1q31NCBI
MPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,778,684 - 154,805,485 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX154,778,684 - 154,821,039 (-)Ensemblhg38GRCh38
GRCh37X154,006,959 - 154,033,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,660,162 - 153,686,957 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X153,570,671 - 153,597,467NCBI
CeleraX154,165,522 - 154,192,359 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,550,319 - 142,577,036 (-)NCBIHuRef
CHM1_1X153,918,634 - 153,945,496 (-)NCBICHM1_1
T2T-CHM13v2.0X153,015,096 - 153,041,895 (-)NCBIT2T-CHM13v2.0
Mpp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X74,153,339 - 74,174,622 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX74,153,339 - 74,174,622 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X75,109,733 - 75,131,016 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX75,109,733 - 75,131,016 (-)Ensemblmm10GRCm38
MGSCv37X72,355,072 - 72,376,288 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X71,362,453 - 71,383,669 (-)NCBIMGSCv36mm8
CeleraX66,514,557 - 66,535,775 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.15NCBI
Mpp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955594831,098 - 846,866 (+)Ensembl
ChiLan1.0NW_004955594831,100 - 846,438 (+)NCBIChiLan1.0ChiLan1.0
MPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X154,757,372 - 154,784,625 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X154,760,980 - 154,788,231 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X144,258,416 - 144,285,658 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X154,099,463 - 154,126,575 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX154,099,463 - 154,126,575 (-)EnsemblpanPan2panpan1.1
MPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,851,667 - 122,878,865 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,851,667 - 122,879,394 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX107,845,285 - 107,872,081 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X125,977,893 - 126,005,109 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX125,977,893 - 126,018,584 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X121,726,260 - 121,753,061 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X124,249,501 - 124,276,287 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X123,942,589 - 123,969,391 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mpp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,788,981 - 119,811,866 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936927147,282 - 170,575 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936927147,448 - 170,435 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX125,229,450 - 125,350,853 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X125,230,412 - 125,252,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X143,231,475 - 143,252,754 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X129,030,736 - 129,057,952 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX129,030,735 - 129,044,777 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606567,008,905 - 67,036,197 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624963445,588 - 467,976 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624963445,559 - 467,976 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mpp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X302,067 - 310,291 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: NM_001037659   ⟹   NP_001032748
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01148,450,213 - 148,458,945 (+)NCBI
Rnor_5.01154,731,975 - 154,741,021 (+)NCBI
Celera1137,539,255 - 137,547,772 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001032748 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91223 (Get FASTA)   NCBI Sequence Viewer  
  BAD27524 (Get FASTA)   NCBI Sequence Viewer  
  EDL83921 (Get FASTA)   NCBI Sequence Viewer  
  EDL83922 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001032748   ⟸   NM_001037659
- UniProtKB: Q6F6B2 (UniProtKB/TrEMBL),   Q5BK33 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Guanylate kinase-like   PDZ   SH3


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594331 AgrOrtholog
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127032 IMAGE-MGC_LOAD
InterPro Guanylate_kin UniProtKB/TrEMBL
  Guanylate_kin/L-typ_Ca_channel UniProtKB/TrEMBL
  Guanylate_kinase_CS UniProtKB/TrEMBL
  MAGUK UniProtKB/TrEMBL
  MPP1_SH3 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
MGC_CLONE MGC:108959 IMAGE-MGC_LOAD
NCBI Gene 652956 ENTREZGENE
PANTHER MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK UniProtKB/TrEMBL
Pfam Guanylate_kin UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PhenoGen Mpp1 PhenoGen
PROSITE GUANYLATE_KINASE_1 UniProtKB/TrEMBL
  GUANYLATE_KINASE_2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART GuKc UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP PDZ UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt Q5BK33 ENTREZGENE, UniProtKB/TrEMBL
  Q6F6B2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-09-23 Mpp1  MAGUK p55 scaffold protein 1  Mpp1  membrane palmitoylated protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-14 Mpp1  membrane palmitoylated protein 1  Mpp1  membrane protein, palmitoylated 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-17 Mpp1  membrane protein, palmitoylated 1  LOC652956  p55 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC652956  p55 protein      Symbol and Name status set to provisional 70820 PROVISIONAL