Gng13 (G protein subunit gamma 13) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: Gng13 (G protein subunit gamma 13) Rattus norvegicus
Analyze
Symbol: Gng13
Name: G protein subunit gamma 13
RGD ID: 1593806
Description: Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway and sensory perception of taste. Predicted to be located in dendrite. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in synapse. Orthologous to human GNG13 (G protein subunit gamma 13); PARTICIPATES IN chemokine mediated signaling pathway; glutamate signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: guanine nucleotide binding protein (G protein), gamma 13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; heterotrimeric guanine nucleotide-binding protein 3j; Hg3j; LOC685451; similar to guanine nucleotide binding protein 13, gamma
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,245,698 - 15,247,602 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1015,245,698 - 15,247,602 (+)EnsemblGRCr8
mRatBN7.21014,741,179 - 14,743,083 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,741,239 - 14,743,083 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1019,480,159 - 19,482,064 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,969,037 - 18,970,942 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,469,359 - 14,471,263 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,088,935 - 15,090,839 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,088,935 - 15,090,839 (+)Ensemblrn6Rnor6.0
Rnor_5.01014,901,656 - 14,903,560 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41014,986,319 - 14,988,223 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1014,410,653 - 14,412,557 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10570481   PMID:12454992   PMID:12606627   PMID:22871113  


Genomics

Comparative Map Data
Gng13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,245,698 - 15,247,602 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1015,245,698 - 15,247,602 (+)EnsemblGRCr8
mRatBN7.21014,741,179 - 14,743,083 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,741,239 - 14,743,083 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1019,480,159 - 19,482,064 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,969,037 - 18,970,942 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,469,359 - 14,471,263 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,088,935 - 15,090,839 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,088,935 - 15,090,839 (+)Ensemblrn6Rnor6.0
Rnor_5.01014,901,656 - 14,903,560 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41014,986,319 - 14,988,223 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1014,410,653 - 14,412,557 (+)NCBICelera
Cytogenetic Map10q12NCBI
GNG13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816798,041 - 800,734 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16798,041 - 800,734 (-)Ensemblhg38GRCh38
GRCh3716848,041 - 850,734 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616788,042 - 790,734 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3416788,042 - 790,700NCBI
Celera161,047,927 - 1,050,619 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16770,609 - 773,301 (-)NCBIHuRef
CHM1_116847,980 - 850,672 (-)NCBICHM1_1
T2T-CHM13v2.016802,865 - 805,558 (-)NCBIT2T-CHM13v2.0
Gng13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,936,146 - 25,938,076 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1725,936,145 - 25,938,380 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381725,717,172 - 25,719,102 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,717,171 - 25,719,406 (+)Ensemblmm10GRCm38
MGSCv371725,854,117 - 25,856,047 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361725,444,824 - 25,446,685 (+)NCBIMGSCv36mm8
Celera1726,249,474 - 26,251,404 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.82NCBI
Gng13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,408,295 - 16,414,608 (+)Ensembl
ChiLan1.0NW_00495544216,408,295 - 16,414,608 (+)NCBIChiLan1.0ChiLan1.0
GNG13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2181,040,543 - 1,043,564 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,824,673 - 4,827,783 (-)NCBINHGRI_mPanPan1
PanPan1.116813,294 - 815,490 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16813,363 - 813,721 (-)EnsemblpanPan2panpan1.1
GNG13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,800,092 - 39,806,959 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,806,528 - 39,806,871 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha641,064,844 - 41,071,622 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0640,143,295 - 40,150,080 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,149,647 - 40,149,990 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,831,932 - 39,838,712 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,792,179 - 39,798,942 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,271,015 - 40,277,796 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gng13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,132,587 - 112,134,566 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501232,009 - 232,413 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936501230,439 - 232,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNG13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,998,504 - 41,000,905 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1340,997,556 - 41,000,718 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,476,315 - 41,478,448 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNG13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606830,415,440 - 30,416,392 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gng13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,603,542 - 1,605,522 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249131,603,548 - 1,605,542 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Gng13
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v192,982,589 - 2,984,547 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gng13
16 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:98
Count of miRNA genes:86
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000030273
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 1 55 116 70 74 50 16 50 6 225 81 1 102 79 80 24 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000030273   ⟹   ENSRNOP00000030270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1015,245,698 - 15,247,602 (+)Ensembl
mRatBN7.2 Ensembl1014,741,239 - 14,743,083 (+)Ensembl
Rnor_6.0 Ensembl1015,088,935 - 15,090,839 (+)Ensembl
RefSeq Acc Id: NM_001135918   ⟹   NP_001129390
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,245,698 - 15,247,602 (+)NCBI
mRatBN7.21014,741,179 - 14,743,083 (+)NCBI
Rnor_6.01015,088,935 - 15,090,839 (+)NCBI
Rnor_5.01014,901,656 - 14,903,560 (+)NCBI
RGSC_v3.41014,986,319 - 14,988,223 (+)RGD
Celera1014,410,653 - 14,412,557 (+)RGD
Sequence:
RefSeq Acc Id: XM_006246034   ⟹   XP_006246096
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,245,888 - 15,247,596 (+)NCBI
mRatBN7.21014,741,393 - 14,743,083 (+)NCBI
Rnor_6.01015,089,174 - 15,090,833 (+)NCBI
Rnor_5.01014,901,656 - 14,903,560 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001129390 (Get FASTA)   NCBI Sequence Viewer  
  XP_006246096 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAZ23842 (Get FASTA)   NCBI Sequence Viewer  
  AAZ23843 (Get FASTA)   NCBI Sequence Viewer  
  CAG9553628 (Get FASTA)   NCBI Sequence Viewer  
  EDM03943 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030270
  ENSRNOP00000030270.6
RefSeq Acc Id: NP_001129390   ⟸   NM_001135918
- UniProtKB: A6HD38 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246096   ⟸   XM_006246034
- Peptide Label: isoform X1
- UniProtKB: A6HD38 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030270   ⟸   ENSRNOT00000030273
Protein Domains
G protein gamma

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V8Y0-F1-model_v2 AlphaFold G3V8Y0 1-67 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697053
Promoter ID:EPDNEW_R7578
Type:single initiation site
Name:Gng13_1
Description:G protein subunit gamma 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01015,088,922 - 15,088,982EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593806 AgrOrtholog
BioCyc Gene G2FUF-25767 BioCyc
Ensembl Genes ENSRNOG00000039350 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030273 ENTREZGENE
  ENSRNOT00000030273.6 UniProtKB/TrEMBL
Gene3D-CATH 4.10.260.10 UniProtKB/TrEMBL
InterPro G-protein_gamma_dom UniProtKB/TrEMBL
  GGL_sf UniProtKB/TrEMBL
  GNG13 UniProtKB/TrEMBL
KEGG Report rno:685451 UniProtKB/TrEMBL
NCBI Gene 685451 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-13 UniProtKB/TrEMBL
  PTHR15936 UniProtKB/TrEMBL
Pfam G-gamma UniProtKB/TrEMBL
PhenoGen Gng13 PhenoGen
PROSITE G_PROTEIN_GAMMA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039350 RatGTEx
SMART G_gamma UniProtKB/TrEMBL
  GGL UniProtKB/TrEMBL
Superfamily-SCOP G-protein_gamma-like UniProtKB/TrEMBL
UniProt A6HD38 ENTREZGENE, UniProtKB/TrEMBL
  G3V8Y0_RAT UniProtKB/TrEMBL
  Q45QJ8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-15 Gng13  G protein subunit gamma 13  Gng13  guanine nucleotide binding protein (G protein), gamma 13  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-07-08 Gng13  guanine nucleotide binding protein (G protein), gamma 13  LOC682159  similar to guanine nucleotide binding protein 13, gamma  Data merged from RGD:1586928 1643240 APPROVED
2008-03-05 Gng13  guanine nucleotide binding protein (G protein), gamma 13  LOC685451  similar to guanine nucleotide binding protein 13, gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC685451  similar to guanine nucleotide binding protein 13, gamma      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC682159  similar to guanine nucleotide binding protein 13, gamma      Symbol and Name status set to provisional 70820 PROVISIONAL