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Gene: Fbxo3 (F-box protein 3) Rattus norvegicus

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Symbol:

Fbxo3

Name:

F-box protein 3

RGD ID:

1593433

Description:

Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and response to lipopolysaccharide. Predicted to act upstream of or within transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human FBXO3 (F-box protein 3); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

F-box only protein 3; LOC690634; similar to F-box only protein 3 isoform 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FBXO3 (F-box protein 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Fbxo3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fbxo3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FBXO3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FBXO3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fbxo3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FBXO3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FBXO3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fbxo3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Fbxo3 (F-box protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CNDP2 (carnosine dipeptidase 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	FBXO3 (F-box protein 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	FBXO3 (F-box protein 3)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Fbxo3 (F-box protein 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Fbxo3 (F-box protein 3)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fbxo3 (F-box protein 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fbxo3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fbxo3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	110,872,185 - 110,904,479 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	110,872,220 - 110,904,479 (+)	Ensembl				GRCr8
mRatBN7.2	3	90,417,262 - 90,449,557 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	90,417,297 - 90,449,557 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	93,910,311 - 93,942,671 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	102,509,388 - 102,541,746 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	100,339,746 - 100,372,121 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	93,968,827 - 94,000,863 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	93,968,855 - 94,000,863 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	100,608,746 - 100,640,793 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	89,446,724 - 89,479,650 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	89,478,591 - 89,510,807 (+)	NCBI		Celera
Cytogenetic Map	3	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

alpha-pinene (ISO)

antirheumatic drug (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

ATP (EXP)

benzene (EXP)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

chlorpyrifos (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diazinon (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

fenofibrate (ISO)

flutamide (EXP)

folic acid (ISO)

fulvestrant (ISO)

gentamycin (EXP)

glafenine (EXP)

hydrogen peroxide (ISO)

indometacin (ISO)

ivermectin (ISO)

leflunomide (ISO)

lipopolysaccharide (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (EXP)

methimazole (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

methylmercury(1+) (EXP)

oxaliplatin (EXP)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

quercetin (ISO)

resveratrol (EXP)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

sulfadimethoxine (EXP)

tetrachloromethane (EXP,ISO)

thimerosal (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein ubiquitination (IEA)

response to lipopolysaccharide (IEA,ISO,ISS)

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (IEA,ISO,ISS)

Cellular Component

cytoplasm (IBA)

nucleus (IEA,ISO)

SCF ubiquitin ligase complex (IEA,ISO,ISS)

Molecular Function

protein binding (ISO)

ubiquitin-like ligase-substrate adaptor activity (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:26674878	PMID:35962723	PMID:36362432

Genomics

Comparative Map Data

Fbxo3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	110,872,185 - 110,904,479 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	110,872,220 - 110,904,479 (+)	Ensembl				GRCr8
mRatBN7.2	3	90,417,262 - 90,449,557 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	90,417,297 - 90,449,557 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	93,910,311 - 93,942,671 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	102,509,388 - 102,541,746 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	100,339,746 - 100,372,121 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	93,968,827 - 94,000,863 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	93,968,855 - 94,000,863 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	100,608,746 - 100,640,793 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	89,446,724 - 89,479,650 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	89,478,591 - 89,510,807 (+)	NCBI		Celera
Cytogenetic Map	3	q32	NCBI

FBXO3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	33,740,944 - 33,774,520 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	33,740,939 - 33,774,543 (-)	Ensembl			hg38	GRCh38
GRCh37	11	33,762,490 - 33,796,066 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	33,719,066 - 33,752,647 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	33,724,868 - 33,752,647	NCBI
Celera	11	33,909,992 - 33,943,582 (-)	NCBI		Celera
Cytogenetic Map	11	p13	NCBI
HuRef	11	33,458,657 - 33,492,237 (-)	NCBI		HuRef
CHM1_1	11	33,762,004 - 33,795,579 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	33,877,954 - 33,911,529 (-)	NCBI		T2T-CHM13v2.0

Fbxo3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	103,858,144 - 103,893,582 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	103,858,066 - 103,893,585 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	104,027,799 - 104,063,237 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	104,027,721 - 104,063,240 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	103,867,956 - 103,903,394 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	103,828,638 - 103,864,076 (+)	NCBI		MGSCv36	mm8
Celera	2	105,265,922 - 105,300,910 (+)	NCBI		Celera
Cytogenetic Map	2	E2	NCBI
cM Map	2	54.49	NCBI

Fbxo3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	12,461,858 - 12,494,553 (+)	Ensembl
ChiLan1.0	NW_004955422	12,462,329 - 12,492,030 (+)	NCBI	ChiLan1.0	ChiLan1.0

FBXO3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	35,960,609 - 35,994,171 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	35,965,323 - 35,998,916 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	33,713,147 - 33,746,730 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	33,594,854 - 33,628,399 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	33,594,854 - 33,628,399 (-)	Ensembl			panPan2	panpan1.1

FBXO3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	33,944,441 - 33,974,944 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	33,944,451 - 33,973,968 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	33,550,035 - 33,580,545 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	34,555,537 - 34,586,084 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	34,555,537 - 34,594,140 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	34,114,297 - 34,144,819 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	33,707,460 - 33,737,980 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	34,343,094 - 34,373,628 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fbxo3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	31,075,996 - 31,108,138 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936533	4,200,757 - 4,234,145 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936533	4,200,791 - 4,232,929 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FBXO3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	27,146,444 - 27,184,181 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	27,146,407 - 27,183,496 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	29,513,804 - 29,539,556 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FBXO3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	31,509,950 - 31,543,421 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	31,509,956 - 31,543,611 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	128,605,747 - 128,639,998 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fbxo3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	13,379,895 - 13,410,210 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624767	13,382,187 - 13,410,143 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fbxo3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	81,847,214 - 81,878,156 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fbxo3
267 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	183
Count of miRNA genes:	148
Interacting mature miRNAs:	163
Transcripts:	ENSRNOT00000014478
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	51490129	111359995	Rat
1358293	Bw38	Body weight QTL 38	6	0.0000031	body mass (VT:0001259)	body weight (CMO:0000012)	3	74364268	119364268	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	96509147	141509147	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	136118980	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	85062224	136118980	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	85062224	136118980	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	104545086	149545086	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	81425008	141509147	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	70845569	136091483	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	93829559	138829559	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	101255536	134750886	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	96509147	141509147	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	70311536	115311536	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	110225882	155225882	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	81541464	126563126	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	90755164	141509147	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	42158111	124558371	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	42158111	124558371	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	110634702	155634702	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat

Markers in Region

RH129889

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	90,444,516 - 90,444,728 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	93,995,823 - 93,996,034	NCBI	Rnor6.0
Rnor_5.0	3	100,635,753 - 100,635,964	UniSTS	Rnor5.0
RGSC_v3.4	3	89,451,554 - 89,451,765	UniSTS	RGSC3.4
Celera	3	89,505,767 - 89,505,978	UniSTS
RH 3.4 Map	3	722.6	UniSTS
Cytogenetic Map	3	q32	UniSTS

RH134289

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	90,448,351 - 90,448,538 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	93,999,658 - 93,999,844	NCBI	Rnor6.0
Rnor_6.0	3	97,134,624 - 97,134,810	NCBI	Rnor6.0
Rnor_5.0	3	103,754,940 - 103,755,126	UniSTS	Rnor5.0
Rnor_5.0	3	100,639,588 - 100,639,774	UniSTS	Rnor5.0
RGSC_v3.4	3	89,447,743 - 89,447,929	UniSTS	RGSC3.4
Celera	3	89,509,602 - 89,509,788	UniSTS
RH 3.4 Map	3	732.0	UniSTS
Cytogenetic Map	3	q32	UniSTS

BF386302

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	90,446,524 - 90,446,693 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	93,997,831 - 93,997,999	NCBI	Rnor6.0
Rnor_5.0	3	100,637,761 - 100,637,929	UniSTS	Rnor5.0
RGSC_v3.4	3	89,449,589 - 89,449,757	UniSTS	RGSC3.4
Celera	3	89,507,775 - 89,507,943	UniSTS
RH 3.4 Map	3	721.7	UniSTS
Cytogenetic Map	3	q32	UniSTS

AI176767

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	90,448,388 - 90,448,538 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	93,999,695 - 93,999,844	NCBI	Rnor6.0
Rnor_6.0	3	97,134,661 - 97,134,810	NCBI	Rnor6.0
Rnor_5.0	3	100,639,625 - 100,639,774	UniSTS	Rnor5.0
Rnor_5.0	3	103,754,977 - 103,755,126	UniSTS	Rnor5.0
RGSC_v3.4	3	89,447,743 - 89,447,892	UniSTS	RGSC3.4
Celera	3	89,509,639 - 89,509,788	UniSTS
Cytogenetic Map	3	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
21	13	80	210	91	90	59	157	59	6	475	279	21	189	108	124	31	33	33

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014478 ⟹ ENSRNOP00000014478

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	110,872,220 - 110,904,479 (+)	Ensembl
mRatBN7.2 Ensembl	3	90,417,297 - 90,449,557 (+)	Ensembl
Rnor_6.0 Ensembl	3	93,968,855 - 94,000,863 (+)	Ensembl

RefSeq Acc Id:

NM_001109606 ⟹ NP_001103076

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	110,872,220 - 110,904,479 (+)	NCBI
mRatBN7.2	3	90,417,297 - 90,449,557 (+)	NCBI
Rnor_6.0	3	93,968,855 - 94,000,863 (+)	NCBI
Rnor_5.0	3	100,608,746 - 100,640,793 (+)	NCBI
RGSC_v3.4	3	89,446,724 - 89,479,650 (-)	RGD
Celera	3	89,478,591 - 89,510,807 (+)	RGD

Sequence:

show sequence

AGGCTGCAGCGGGCTGGGCAAGATGGCTGCCGTAGAGGCCGAGACAGGGTTGCTGACCCTGGAG
TCGCTACCCACCGACCCTCTGCTCCTCATCTTATCCTTCGTGGACTACAGGGACCTAATCAATT
GTTGCTATGTTAGTCGAAGACTTAGCCAGCTATCAACTCATGATCCACTGTGGAGAAGACATTG
CAAAAAATACTGGCTGATAACTGAGGAAGAGAAAGCCCGGAAGAATCAGTGCTGGAAATCTCTC
TTCATAGCTACTTACTCAGATGTAGGAAGATACATCAACCATTATGCTGCTATTAAAAAGGCCT
GGGATGACCTCAAGAAGTACTTGGAGCCTAGGTGTCCTCGGATGGTTTTATCTCTGAAAGAGGG
TGCGCGTGAGGAAGACCTGGATGCAGTAGAAGCTCAGATCGGTTGCAAGCTCCCCGATGACTAT
CGCTGCTCATACCGGATCCACAATGGGCAGAAGTTAGTGGTTCCAGGATTGCTGGGAAGCATGG
CACTGTCAAATCACTACCGCTCTGAAGATTTATTAGACGTTGACACTGCTGCCGGAGGATTTCA
GCAGAGACAGGGACTGAAATACTGTCTCCCTTTAACCTTTTGCATACATACTGGCTTGAGTCAG
TACATAGCTGTGGAAGCTGCAGAGGGCCGAAATAAAAACGAAGTGTTCTACCAGTGCCCAGATC
AAATGGCTCGGAATCCTGCTGCTATTGACATGTTTATCATAGGTGCTACTTTTACTGACTGGTT
TACATCCTATGTCAACAATGTTGTATCAGGTGGCTTCCCCATCATCAGAGACCAGATTTTCAGA
TATATTCATGACCCAGAGTGTGTAGCAACAACTGGAGATATTACAGTCTCAGTGTCCACATCGT
TTCTGCCAGAACTCAGTTCTGTGCACCCACCACACTATTTCTTCACATACCGAATCAGGATTGA
AATGTCAAGGGATGCTCTTCCTGAGAAGGCCTGTCAGTTGGACAGTCGCTACTGGAGGATAACA
AATGCTAAAGGGGATGTGGAGGAAGTCCAGGGACCTGGAGTAGTTGGTGAATTTCCAATTATTA
GCCCAGGTCGGATATATGAATACACCAGCTGCACCACATTTTCTACAACATCAGGCTATATGGA
AGGGTATTATACCTTCCATTTTCTGTACTTTAAGGACAAGGTCTTTAATGTTGCCATCCCACGA
TTCCATATGGCATGCCCAACATTCAGGGTGTCTATAGCCCGATTGGAAATGGGTCCTGATGAAT
ATGAAGAGATGGAGGAGGAAGCTGAGGAGGAAGAGGAAGAGGAAAACGATGACTCAGCAGACAT
GGATGAATCCGATGAATCAGATGAGGATGAGAATGAATCAGATGAGGGTGAAGGGGAGGAGAGA
AGGAGGAGGGTCTTTGATGTTCCCATCCGCAGACGCCGCTGCTCTCGTCTTTTTTAGCTGCTGC
TGAAGGAAGCTCTGGAATGACACTATTCTGTTAAATAGATTTGTCAATAATGTAAATAATTGTG
CTCAGCATATAGCAGGAAACTAGCACGGAATGTTCCAGACCTAGGCTCTACACGACACTACATT
AGGAGTTGGATCGCTTTGCTTTGTTTTGTGGTTGTAGGTAGCAGAAGAAAAGGAAATTGTTTTC
TCTTCCAGAGTCCATGGGAGAGCAATTCTATAGTTGAAGAACAGATGTTCCTTTGTTTAAAAAT
ATTTTCTACTTAAAAACAAAACACAGAGGTGAAGAGAAAATTGTTTTGGGTGAGGATTTTATAT
GTAGCAGAAATACCCACACCAGGGTAGAAGAGACTATGACTGACTGTGAAAAGACCCCTTCTGT
TGTTTAGAAACTAACAAAATTTGTAATTAGCTTCATCCATTTCATGGTTGTTAATAGTTTATAC
TCATGGGGAACTAAATGACTAACTTGAATAGGAATAGTTTGCCCTTTCTTAGACAATCTGTCCT
CGAATTAGTCTTTGTCACACAGACCTTGAGTTGCAGTTTTCATCATTACTTTTAAAATCTTCAA
CATAACTTTGGACTTTAAAAGTTAGAGTTCTCACGCTATGACCTTTCTCACATCATTTACAGAT
TCCTCATTTTAAATGTGGTTTGTAAAAGTACGTAGAGTGTTGTTAAAGATTCTTCACAATGTCT
CATGTAGTCTAAATTTGTAAATATGCTTTCTGTTCTGTTTCCTTATACATTTGTCTAACTTTGT
GGTAAGTGATCTGAATTTTATGTTAGGGTTAGGATATTTTCGTGAAACATGGATTTTTTTGTAA
TTATATAATTGAGAGTTTGGAATGAAATCCTTCAAGTGTCAAAAACTCCTGTTTTAAAAACTTT
TGTGTAAGTGCCTATTTCCCGTAGACTGCTGAGCTTTGTTCTTAAGCTAGAAGATGGCAGTGCT
ACTTGCTGGCCTACAGCCAGAGGACAGCAGGTCCATTCAGAGTTGACTGCTGCCTTTGATTATG
CTCTTTTGCTCTCCATCAATATTCCTGTAAAACAGTTCAGTCGTGGAGAAAATTTAGGAAGAGA
GCGTCATGTTCAAGACTAAGTGCCTGCTCTCAGGGACTATGAGCAAACTTGCCCTTTTATGAAG
ACAGATCAGAATATTCCAAGTCATTTTCCTACTTACCTTTCATAGGAGAGTATACTCACATGGT
GTTTCAACAACAAGCCAGCAGCAGCCTCATCTTCTGTATACCACATCTGTTGAATGTATCGTTT
TTTCTCCTGTGCTTGATTAAACCTCATGTTGTTTGTTTGTTATGGCCCCACAGCATACGGAATC
ACTGCTAAGGTTGAGAGTAAGTTGTCATCAAGTGATCCACCCAGAAATGAAATTTAAATGAAGG
ACTTAGAAACAAGGGGGGTGGGGATCACTGATGGCTACTGCTTATTAAGTCAGCTGCTCTACCA
TAGCTAGACCCTCAAAGAACAAGAGCAGATGGGACATAAATTGTTGGAACATCTGCTTCATTGA
CGGCAATATGAATATTTCAAGAAAGGTCAATATCAGATCTGGAGGCCCTTATAATCACCTGACT
TGACACAAATGTGCCTTCTACATCATGATGTCCACTGCCAAAGCAGGGTTTGCCTACAAGAGTG
AAAGAGAAGACTAGACCTGACTAGGATGTCGGGGTTACTGAGAGCTCTGGGTGGTCTAAAGTGA
ATAATCGTTAGGAAATTTGAAAGTAAGTGGTAAGCCTGCAAACTTGTGGGTGAAGAATGCTAAC
TTTAAAAGGTAGAAACTGGGTGTGTGGAGTGGTTACTTGCCAACGCAAACCCTCCTCTATTCCA
TCTAGGTTTGTATAAAATACATTCTGTGTGGTTTGCAAGGTGATAAAATAGCTTGTCACTACAA
TCACCTAATGACTCATTTCTTAAAATCTAATCCCATTGTTAAGTGAGAACATGACTATTATCAG
ACTGCCAAATACTATCAGGCTACCCTTCCTTTTTTTTTTTTTTTTTTTTCTTTTTTCTTTTTTT
CGGAGCTGGGGACTGAACTCAGGGCCTTCCGCTTGCTAGGCAAGCCCTCTACCACTGAGCTAAA
TCCCCAACCCCCAGGCTACCCTTCTTAAAAATAGTCAACT

hide sequence

RefSeq Acc Id:

XM_006234656 ⟹ XP_006234718

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	110,872,185 - 110,899,785 (+)	NCBI
mRatBN7.2	3	90,417,262 - 90,445,555 (+)	NCBI
Rnor_6.0	3	93,968,827 - 93,998,050 (+)	NCBI
Rnor_5.0	3	100,608,746 - 100,640,793 (+)	NCBI

Sequence:

show sequence

GCGGCGGGGGCGGGGCCGGGGTGGTGCCAGGCTGCAGCGGGCTGGGCAAGATGGCTGCCGTAGA
GGCCGAGACAGGGTTGCTGACCCTGGAGTCGCTACCCACCGACCCTCTGCTCCTCATCTTATCC
TTCGTGGACTACAGGGACCTAATCAATTGTTGCTATGTTAGTCGAAGACTTAGCCAGCTATCAA
CTCATGATCCACTGTGGAGAAGACATTGCAAAAAATACTGGCTGATAACTGAGGAAGAGAAAGC
CCGGAAGAATCAGTGCTGGAAATCTCTCTTCATAGCTACTTACTCAGATGTAGGAAGATACATC
AACCATTATGCTGCTATTAAAAAGGCCTGGGATGACCTCAAGAAGTACTTGGAGCCTAGGTGTC
CTCGGATGGTTTTATCTCTGAAAGAGGGTGCGCGTGAGGAAGACCTGGATGCAGTAGAAGCTCA
GATCGGTTGCAAGCTCCCCGATGACTATCGCTGCTCATACCGGATCCACAATGGGCAGAAGTTA
GTGGTTCCAGGATTGCTGGGAAGCATGGCACTGTCAAATCACTACCGCTCTGAAGATTTATTAG
ACGTTGACACTGCTGCCGGAGGATTTCAGCAGAGACAGGGACTGAAATACTGTCTCCCTTTAAC
CTTTTGCATACATACTGGCTTGAGTCAGTACATAGCTGTGGAAGCTGCAGAGGGCCGAAATAAA
AACGAAGTGTTCTACCAGTGCCCAGATCAAATGGCTCGGAATCCTGCTGCTATTGACATGTTTA
TCATAGGTGCTACTTTTACTGACTGGTTTACATCCTATGTCAACAATGTTGTATCAGGTGGCTT
CCCCATCATCAGAGACCAGATTTTCAGATATATTCATGACCCAGAGTGTGTAGCAACAACTGGA
GATATTACAGTCTCAGTGTCCACATCGTTTCTGCCAGAACTCAGTTCTGTGCACCCACCACACT
ATTTCTTCACATACCGAATCAGGATTGAAATGTCAAGGGATGCTCTTCCTGAGAAGGCCTGTCA
GTTGGACAGTCGCTACTGGAGGATAACAAATGCTAAAGGGGATGTGGAGGAAGTCCAGGGACCT
GGAGTAGTTGGTGAATTTCCAATTATTAGCCCAGGTCGGATATATGAATACACCAGCTGCACCA
CATTTTCTACAACATCAGGCTATATGGAAGGGTATTATACCTTCCATTTTCTGTACTTTAAGGA
CAAGGTCTTTAATGTTGCCATCCCACGATTCCATATGGCATGCCCAACATTCAGGGTGTCTATA
GCCCGATTGCCACAACATTTCTATTGATCATTGAAAAGGAACAACACTTCGTTTTGATGGATTT
TCTGTAGTTTCTCTTTTCTATTTCACGCTTGGTGCACTTGTTTTTATTTCTCTTCTGCTTACCT
TGGGTTTCATTCGCTTTTCCTGTAGCTTTTAAAGGTAGAAGTTTAATTATCGACTGTAGACCTT
TCCTGTTTCTAAGCCCTGTTTTAGCTGTTATTGTACAAATTCTGATGTTATATTTTGGTTAATA
TTTAGTTCAAAATACTCTCAGATTTTCCTTGTAACTGATTTAAGACTGCATAGAAATATGTTAA
TTTTCAAGTGTTTGGAAGATTTTAGTTATCTTTTGCTTATTGATTTCTAATATTGTGGTTAGAG
AACTTATTTTGTATTGCTAATATTTTTTAATGTTTTATGACCCCAAATTATGTGAAGAATTTCT
ATATCTTGGTCAATGATCTTTGTGTCTTTGAAAAGAATGTATACTCTACCATGTGAGAATTTAT
TCTATAAATGACAGGCCACACTGGCTGGTTGTTTGCCAGTGTGTGTCAAGTCATCTGTATTTTT
ATTGCTCTTTCTTTAAACTTTTGTTATTTCAACCATTGAAGAGATTATTGTTGAAATCTTTAAT
GGCTTTGCCCACTGCTTACTTTATTCTTGTCACATTTGCCTCATGCATTTTGAAGTTATGTACT
TGTGTGCCAGTGCTTAGATTGTTGTCTGTTTACGACAGTGGTTCTTTGACTCTTATTCGTCTCT
AATAACATTCCTTGTCCTAGCTTAAGAGCATTGAGGCATGCGTGGGCAGGCAGTCGAGTTGGGT
CAGTTGATCCTTTTGTTGCTTGTCTTTAATATTTGTTTCAGTGGATGTAAAGTATGGGTTTAAA
GACAGTGGTTCTCAAGCCTTTGGGCCTCACCACCTCCTTAGATGTATAAACACCATTGATGCCT
AAGAACCTGTTTACACAGTCATTGTCAGTATTTACCATATTGGAAATGAAAACAGGACAGTTAT
AATAGTATCAGTTCCTTTTAAAATTAAAATAAATAAACCCTTTACATGTTCAACCCTCTCAACT
GTATTTATTTATTTAAAGCTTTTGTTTCTGCTCAACTACAAGAAAAAGTATTTGACTTGTTTTA
CAGAAAGTGTTTTTTCAAAGATGGAGAGTCATTAGAAAAAAATGAGAATTGTGACTTAATCAAC
ATAAAAAAGACAGTAGGGCTGTATTTATTGACCTTTCTTATTTCTGTTATCTTCCTTGATATGG
AAGTTGAATTTTGTTTTGCATTTTTGTCCCCCACCAGTCTGATTAATTGCTAGGCTTCATAATT
TTTTTTTTATACTTGACACTGTAAATGGCTTCTCTGCTTAGTTTAATGATGTCCCTGTGTAGTT
ATTTACTGTGCTTGACTGAGGCACTAGGAACATTCTGGATGCTTCTTTATGTCCCTTCTCCTCT
CTTGTCTGCTATTCCTATAGTACACTATCATCTGAATATTTCTCTTTCTAATCACAGTTGATTC
CTTTAACAGTTCTTGTTTTCTTAATATAATAATCATACTACCTGATAATCATGTTTTAGGATTT
CCAAAGGCTTCCCCATCCCTCCTTTTGTACCTCCTGCAAAATTTTGAAGTCTTCAGTCCTTAGA
TTTAAAAAAAAAATCTGAAGTTAAAAATAATGAAATAACATAAGTCACATTTGTGTATATTTTC
TGATTGTTATTGTGTGTTATAATAAATCCTAAATGACACAATTCTTTTCTCCTACATTTTCATT
TGCTCTCTCAACAAGTGAGTACTGTAGCAAACAATATAATCAAAAGCCTTGGATTTCATACTCT
ATTTGGAAGGAAAGAACTAATATGTGCTCTTGGGTCAAGTATCAAATGTGGTAGAAAAAATTAG
GTGCTAAAGGGAGTATCCTGTCGGGCTCTGTTCTAAAGATGTATCAGGAAAGGTCTTGGTAATA
TCTAAGTAGAAATATGGAAGGAAGGAAGGAAGGAAGGAAGGAGGGAGGGAAGGAAGGAGGGAAG
GAAGGAAGGAAGGAAGGAAGCCATGAAGCCATGTGGATTTGTGGAATAATATTCAGCCAAGAAG
TACTTGGTATGAGGGTTCTTAGGCAACTGTGAGCTTAGTGTGATCGCAGTAGGCTTGAGTACAG
AGAACAGTTATAAATGAGGTCAGAATAGCCACTCTCAGTACATGAGAGCCTGTTATAAAAAAGA
GGGGCCAGAGTAGTGCTAATGATATTAATGCAGTAAAAGCCATTGTGGGGGGACTTTTGTTGAC
ACCATGTACTAAATTTCTCAGTACTGAGATGGCCAGCTGAGCCCTGACTCTTCATTGAGTCTTC
AGCTGTGTGTTAGAGAAGATTAGCAGCCAAATTATAGCCACAACTCGATTGGGGATGCCTGCTT
AAGCAGAATGGCATTCCAAGAGATGGTCTGACACTGCATGCTCCTCGCCTCTCCTGTCTTAGAG
CCTTCACAGCTCCCTTTTCCTACAGTCTTGAGTGGTCTTAGGAATGCATCTCTCTAGGGACTCG
GCAAAGTAACACTCGGCTGAGGCTGAGTTAGAAAAGGCAGTCTGCCTTTAGGCCTGGAACATTT
GCCTTTGGTGTCCTGGGACCTAGTGTGAGAAGTCCAGTTCCCATGAAGCAGCCATAGAAAGCCT
GTAGAGATTTAACCTCAAGGTGGAAGGAAGTGCCCACTCCAGGCTCCAGATATTTGGATCATCC
CAGTCCAGGTACCAGACATGTGAGTGAAGAAGCCCTTGAGGTGAAGCTTGGTTCCAGTCATCAT
TCAGCTGTATCACCATGAGAGACTTGAAGCCAGAAGTATTCCATTGAGTGCTTCCCAGATATCC
AACCACGGAAGCCAAGAGAAGACAATTGACTGTTGTTGTTACGAGCAACTGGAAAAATAAAATA
TTTCTTTTTCAAAA

hide sequence

RefSeq Acc Id:

XM_006234657 ⟹ XP_006234719

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	110,872,185 - 110,899,785 (+)	NCBI
mRatBN7.2	3	90,417,262 - 90,443,789 (+)	NCBI
Rnor_6.0	3	93,968,827 - 93,998,050 (+)	NCBI
Rnor_5.0	3	100,608,746 - 100,640,793 (+)	NCBI

Sequence:

show sequence

GCGGCGGGGGCGGGGCCGGGGTGGTGCCAGGCTGCAGCGGGCTGGGCAAGATGGCTGCCGTAGA
GGCCGAGACAGGGTTGCTGACCCTGGAGTCGCTACCCACCGACCCTCTGCTCCTCATCTTATCC
TTCGTGGACTACAGGGACCTAATCAATTGTTGCTATGTTAGTCGAAGACTTAGCCAGCTATCAA
CTCATGATCCACTGTGGAGAAGACATTGCAAAAAATACTGGCTGATAACTGAGGAAGAGAAAGC
CCGGAAGAATCAGTGCTGGAAATCTCTCTTCATAGCTACTTACTCAGATGTAGGAAGATACATC
AACCATTATGCTGCTATTAAAAAGGCCTGGGATGACCTCAAGAAGTACTTGGAGCCTAGGTGTC
CTCGGATGGTTTTATCTCTGAAAGAGGGTGCGCGTGAGGAAGACCTGGATGCAGTAGAAGCTCA
GATCGGTTGCAAGCTCCCCGATGACTATCGCTGCTCATACCGGATCCACAATGGGCAGAAGTTA
GTGGTTCCAGGATTGCTGGGAAGCATGGCACTGTCAAATCACTACCGCTCTGAAGATTTATTAG
ACGTTGACACTGCTGCCGGAGGATTTCAGCAGAGACAGGGACTGAAATACTGTCTCCCTTTAAC
CTTTTGCATACATACTGGCTTGAGTCAGTACATAGCTGTGGAAGCTGCAGAGGGCCGAAATAAA
AACGAAGTGTTCTACCAGTGCCCAGATCAAATGGCTCGGAATCCTGCTGCTATTGACATGTTTA
TCATAGGTGCTACTTTTACTGACTGGTTTACATCCTATGTCAACAATGTTGTATCAGGTGGCTT
CCCCATCATCAGAGACCAGATTTTCAGATATATTCATGACCCAGAGTGTGTAGCAACAACTGGA
GATATTACAGTCTCAGTGTCCACATCGTTTCTGCCAGAACTCAGTTCTGTGCACCCACCACACT
ATTTCTTCACATACCGAATCAGGATTGAAATGTCAAGGGATGCTCTTCCTGAGAAGGCCTGTCA
GTTGGACAGTCGCTACTGGAGGATAACAAATGCTAAAGGGGATGTGGAGGAAGTCCAGGGACCT
GGAGTAGTTGGTGAATTTCCAATTATTAGCCCAGGTCGGATATATGAATACACCAGCTGCACCA
CATTTTCTACAACATCAGGCTATATGGAAGGGTATTATACCTTCCATTTTCTGTACTTTAAGGA
CAAGGTCTTTAATGTTGCCATCCCACGATTCCATATGGCATGCCCAACATTCAGGGTGTCTATA
GCCCGATTGCCTCCCAAGTGCTAGATGTGTGCACCATGCCTACACCAGACCAGACTTGCATTCT
TGGCCTACATCAGACCAGACTTCCATTCTTGGTTAGCCCAGAACCTATCTGAGCGTGGTACCAT
CCTATCCTTAAGTGGTGATATTCATCAGTGAAGCTGTCTGGAACTGGAGTTTGCTTTATGGGGA
AATTTTAAAATACGGACTTAATTTCTTTAATACGTATATTTTCTATTCTTTCTTGTTTCAGTTT
TGTGCCTTTCATAAAATTTGTTTATTTCATCTAAATGTTGAATTTATTAGCATAAAGTTATTTA
CAATATCCGTTGATCTCCTTTTTATGACTACAAAAGCTGTAGTCACATAACCTTCTTTTATTCC
TAATATTGGTGATTTATATCTTTTTTTAGCCACAACATTTCTATTGATCATTGAAAAGGAACAA
CACTTCGTTTTGATGGATTTTCTGTAGTTTCTCTTTTCTATTTCACGCTTGGTGCACTTGTTTT
TATTTCTCTTCTGCTTACCTTGGGTTTCATTCGCTTTTCCTGTAGCTTTTAAAGGTAGAAGTTT
AATTATCGACTGTAGACCTTTCCTGTTTCTAAGCCCTGTTTTAGCTGTTATTGTACAAATTCTG
ATGTTATATTTTGGTTAATATTTAGTTCAAAATACTCTCAGATTTTCCTTGTAACTGATTTAAG
ACTGCATAGAAATATGTTAATTTTCAAGTGTTTGGAAGATTTTAGTTATCTTTTGCTTATTGAT
TTCTAATATTGTGGTTAGAGAACTTATTTTGTATTGCTAATATTTTTTAATGTTTTATGACCCC
AAATTATGTGAAGAATTTCTATATCTTGGTCAATGATCTTTGTGTCTTTGAAAAGAATGTATAC
TCTACCATGTGAGAATTTATTCTATAAATGACAGGCCACACTGGCTGGTTGTTTGCCAGTGTGT
GTCAAGTCATCTGTATTTTTATTGCTCTTTCTTTAAACTTTTGTTATTTCAACCATTGAAGAGA
TTATTGTTGAAATCTTTAATGGCTTTGCCCACTGCTTACTTTATTCTTGTCACATTTGCCTCAT
GCATTTTGAAGTTATGTACTTGTGTGCCAGTGCTTAGATTGTTGTCTGTTTACGACAGTGGTTC
TTTGACTCTTATTCGTCTCTAATAACATTCCTTGTCCTAGCTTAAGAGCATTGAGGCATGCGTG
GGCAGGCAGTCGAGTTGGGTCAGTTGATCCTTTTGTTGCTTGTCTTTAATATTTGTTTCAGTGG
ATGTAAAGTATGGGTTTAAAGACAGTGGTTCTCAAGCCTTTGGGCCTCACCACCTCCTTAGATG
TATAAACACCATTGATGCCTAAGAACCTGTTTACACAGTCATTGTCAGTATTTACCATATTGGA
AATGAAAACAGGACAGTTATAATAGTATCAGTTCCTTTTAAAATTAAAATAAATAAACCCTTTA
CATGTTCAACCCTCTCAACTGTATTTATTTATTTAAAGCTTTTGTTTCTGCTCAACTACAAGAA
AAAGTATTTGACTTGTTTTACAGAAAGTGTTTTTTCAAAGATGGAGAGTCATTAGAAAAAAATG
AGAATTGTGACTTAATCAACATAAAAAAGACAGTAGGGCTGTATTTATTGACCTTTCTTATTTC
TGTTATCTTCCTTGATATGGAAGTTGAATTTTGTTTTGCATTTTTGTCCCCCACCAGTCTGATT
AATTGCTAGGCTTCATAATTTTTTTTTTATACTTGACACTGTAAATGGCTTCTCTGCTTAGTTT
AATGATGTCCCTGTGTAGTTATTTACTGTGCTTGACTGAGGCACTAGGAACATTCTGGATGCTT
CTTTATGTCCCTTCTCCTCTCTTGTCTGCTATTCCTATAGTACACTATCATCTGAATATTTCTC
TTTCTAATCACAGTTGATTCCTTTAACAGTTCTTGTTTTCTTAATATAATAATCATACTACCTG
ATAATCATGTTTTAGGATTTCCAAAGGCTTCCCCATCCCTCCTTTTGTACCTCCTGCAAAATTT
TGAAGTCTTCAGTCCTTAGATTTAAAAAAAAAATCTGAAGTTAAAAATAATGAAATAACATAAG
TCACATTTGTGTATATTTTCTGATTGTTATTGTGTGTTATAATAAATCCTAAATGACACAATTC
TTTTCTCCTACATTTTCATTTGCTCTCTCAACAAGTGAGTACTGTAGCAAACAATATAATCAAA
AGCCTTGGATTTCATACTCTATTTGGAAGGAAAGAACTAATATGTGCTCTTGGGTCAAGTATCA
AATGTGGTAGAAAAAATTAGGTGCTAAAGGGAGTATCCTGTCGGGCTCTGTTCTAAAGATGTAT
CAGGAAAGGTCTTGGTAATATCTAAGTAGAAATATGGAAGGAAGGAAGGAAGGAAGGAAGGAGG
GAGGGAAGGAAGGAGGGAAGGAAGGAAGGAAGGAAGGAAGCCATGAAGCCATGTGGATTTGTGG
AATAATATTCAGCCAAGAAGTACTTGGTATGAGGGTTCTTAGGCAACTGTGAGCTTAGTGTGAT
CGCAGTAGGCTTGAGTACAGAGAACAGTTATAAATGAGGTCAGAATAGCCACTCTCAGTACATG
AGAGCCTGTTATAAAAAAGAGGGGCCAGAGTAGTGCTAATGATATTAATGCAGTAAAAGCCATT
GTGGGGGGACTTTTGTTGACACCATGTACTAAATTTCTCAGTACTGAGATGGCCAGCTGAGCCC
TGACTCTTCATTGAGTCTTCAGCTGTGTGTTAGAGAAGATTAGCAGCCAAATTATAGCCACAAC
TCGATTGGGGATGCCTGCTTAAGCAGAATGGCATTCCAAGAGATGGTCTGACACTGCATGCTCC
TCGCCTCTCCTGTCTTAGAGCCTTCACAGCTCCCTTTTCCTACAGTCTTGAGTGGTCTTAGGAA
TGCATCTCTCTAGGGACTCGGCAAAGTAACACTCGGCTGAGGCTGAGTTAGAAAAGGCAGTCTG
CCTTTAGGCCTGGAACATTTGCCTTTGGTGTCCTGGGACCTAGTGTGAGAAGTCCAGTTCCCAT
GAAGCAGCCATAGAAAGCCTGTAGAGATTTAACCTCAAGGTGGAAGGAAGTGCCCACTCCAGGC
TCCAGATATTTGGATCATCCCAGTCCAGGTACCAGACATGTGAGTGAAGAAGCCCTTGAGGTGA
AGCTTGGTTCCAGTCATCATTCAGCTGTATCACCATGAGAGACTTGAAGCCAGAAGTATTCCAT
TGAGTGCTTCCCAGATATCCAACCACGGAAGCCAAGAGAAGACAATTGACTGTTGTTGTTACGA
GCAACTGGAAAAATAAAATATTTCTTTTTCAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001103076	(Get FASTA)	NCBI Sequence Viewer
	XP_006234718	(Get FASTA)	NCBI Sequence Viewer
	XP_006234719	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D4ABP9	(Get FASTA)	NCBI Sequence Viewer
	EDL79684	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014478
	ENSRNOP00000014478.2

RefSeq Acc Id:

NP_001103076 ⟸ NM_001109606

- UniProtKB:

D4ABP9 (UniProtKB/Swiss-Prot), A6HNT3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAVEAETGLLTLESLPTDPLLLILSFVDYRDLINCCYVSRRLSQLSTHDPLWRRHCKKYWLIT
EEEKARKNQCWKSLFIATYSDVGRYINHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLD
AVEAQIGCKLPDDYRCSYRIHNGQKLVVPGLLGSMALSNHYRSEDLLDVDTAAGGFQQRQGLKY
CLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVNNV
VSGGFPIIRDQIFRYIHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSRDALP
EKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRIYEYTSCTTFSTTSGYMEGYYTFHF
LYFKDKVFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEAEEEEEEENDDSADMDESDESD
EDENESDEGEGEERRRRVFDVPIRRRRCSRLF

hide sequence

RefSeq Acc Id:	XP_006234718 ⟸ XM_006234656
- Peptide Label:	isoform X1
- UniProtKB:	A6HNT3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAVEAETGLLTLESLPTDPLLLILSFVDYRDLINCCYVSRRLSQLSTHDPLWRRHCKKYWLIT EEEKARKNQCWKSLFIATYSDVGRYINHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLD AVEAQIGCKLPDDYRCSYRIHNGQKLVVPGLLGSMALSNHYRSEDLLDVDTAAGGFQQRQGLKY CLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVNNV VSGGFPIIRDQIFRYIHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSRDALP EKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRIYEYTSCTTFSTTSGYMEGYYTFHF LYFKDKVFNVAIPRFHMACPTFRVSIARLPQHFY hide sequence

RefSeq Acc Id:	XP_006234719 ⟸ XM_006234657
- Peptide Label:	isoform X2
- UniProtKB:	A6HNT3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAVEAETGLLTLESLPTDPLLLILSFVDYRDLINCCYVSRRLSQLSTHDPLWRRHCKKYWLIT EEEKARKNQCWKSLFIATYSDVGRYINHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLD AVEAQIGCKLPDDYRCSYRIHNGQKLVVPGLLGSMALSNHYRSEDLLDVDTAAGGFQQRQGLKY CLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVNNV VSGGFPIIRDQIFRYIHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSRDALP EKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRIYEYTSCTTFSTTSGYMEGYYTFHF LYFKDKVFNVAIPRFHMACPTFRVSIARLPPKC hide sequence

Ensembl Acc Id:

ENSRNOP00000014478 ⟸ ENSRNOT00000014478

Protein Domains

ApaG F-box

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ABP9-F1-model_v2	AlphaFold	D4ABP9	1-480	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692257

Promoter ID:

EPDNEW_R2782

Type:

initiation region

Name:

Fbxo3_1

Description:

F-box protein 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	93,968,874 - 93,968,934	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1593433	AgrOrtholog
BioCyc Gene	G2FUF-48545	BioCyc
Ensembl Genes	ENSRNOG00000009549	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000014478	ENTREZGENE
	ENSRNOT00000014478.5	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.1280.50	UniProtKB/Swiss-Prot
	2.60.40.1470	UniProtKB/Swiss-Prot
	3.40.1580.10	UniProtKB/Swiss-Prot
InterPro	ApaG_domain	UniProtKB/Swiss-Prot
	ApaG_sf	UniProtKB/Swiss-Prot
	F-box-like_dom_sf	UniProtKB/Swiss-Prot
	F-box_dom	UniProtKB/Swiss-Prot
	F-box_SCF_Substrate_Recog	UniProtKB/Swiss-Prot
	Knr4/Smi1-like_dom	UniProtKB/Swiss-Prot
	Knr4/Smi1-like_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:690634	UniProtKB/Swiss-Prot
NCBI Gene	690634	ENTREZGENE
PANTHER	F-BOX ONLY PROTEIN 3	UniProtKB/Swiss-Prot
	F-BOX ONLY PROTEIN 3	UniProtKB/Swiss-Prot
Pfam	DUF525	UniProtKB/Swiss-Prot
	F-box-like	UniProtKB/Swiss-Prot
	SMI1_KNR4	UniProtKB/Swiss-Prot
PhenoGen	Fbxo3	PhenoGen
PROSITE	APAG	UniProtKB/Swiss-Prot
	FBOX	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000009549	RatGTEx
SMART	FBOX	UniProtKB/Swiss-Prot
	SMI1_KNR4	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF110069	UniProtKB/Swiss-Prot
	SSF160631	UniProtKB/Swiss-Prot
	SSF81383	UniProtKB/Swiss-Prot
UniProt	A6HNT3	ENTREZGENE, UniProtKB/TrEMBL
	D4ABP9	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Fbxo3	F-box protein 3	LOC690634	similar to F-box only protein 3 isoform 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC690634	similar to F-box only protein 3 isoform 1	LOC687307	similar to F-box only protein 3 isoform 1	Data merged from RGD:1586590	1643240	APPROVED
2006-11-20	LOC690634	similar to F-box only protein 3 isoform 1			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC687307	similar to F-box only protein 3 isoform 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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