Mr1 (major histocompatibility complex, class I-related) - Rat Genome Database

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Gene: Mr1 (major histocompatibility complex, class I-related) Rattus norvegicus
Analyze
Symbol: Mr1
Name: major histocompatibility complex, class I-related
RGD ID: 1593291
Description: Predicted to enable T cell receptor binding activity and beta-2-microglobulin binding activity. Predicted to be involved in several processes, including T cell differentiation in thymus; defense response to Gram-positive bacterium; and positive regulation of T cell mediated cytotoxicity directed against tumor cell target. Predicted to act upstream of or within defense response to Gram-negative bacterium. Predicted to be located in endoplasmic reticulum membrane; endosome membrane; and plasma membrane. Predicted to be part of MHC class I protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MR1 (major histocompatibility complex, class I-related); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: histocompatibility-2 complex class 1-like sequence; Hlals; Hlals_mapped; major histocompatibility complex class I-related gene protein; major histocompatibility complex class I-related protein 1; MHC class I-like sequence; MHC class I-like sequence (mapped); MHC class I-related; MHC class I-related gene; MHC class I-related protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,850,420 - 69,868,302 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1369,850,420 - 69,868,502 (-)EnsemblGRCr8
mRatBN7.21367,298,362 - 67,317,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,299,585 - 67,317,970 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1369,885,111 - 69,903,051 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,198,901 - 71,216,775 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,459,561 - 68,477,314 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,771,992 - 72,789,861 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)Ensemblrn6Rnor6.0
Rnor_5.01377,707,537 - 77,725,396 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41370,089,637 - 70,107,384 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1367,175,718 - 67,193,248 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
acyclovir  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bupropion  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
camptothecin  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
cocaine  (EXP)
corosolic acid  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gefitinib  (ISO)
glyphosate  (EXP)
GSK-J4  (ISO)
hydrochlorothiazide  (ISO)
ifosfamide  (ISO)
iopromide  (ISO)
lincomycin  (ISO)
mefenamic acid  (ISO)
methyl methanesulfonate  (ISO)
minocycline  (ISO)
nickel atom  (ISO)
norfloxacin  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
piperacillin  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
propanal  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
Repaglinide  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rofecoxib  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfasalazine  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9553154   PMID:12137932   PMID:20581831   PMID:21190736   PMID:26795251   PMID:27043408   PMID:27527800   PMID:31959982  


Genomics

Comparative Map Data
Mr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,850,420 - 69,868,302 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1369,850,420 - 69,868,502 (-)EnsemblGRCr8
mRatBN7.21367,298,362 - 67,317,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,299,585 - 67,317,970 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1369,885,111 - 69,903,051 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,198,901 - 71,216,775 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,459,561 - 68,477,314 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,771,992 - 72,789,861 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)Ensemblrn6Rnor6.0
Rnor_5.01377,707,537 - 77,725,396 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41370,089,637 - 70,107,384 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1367,175,718 - 67,193,248 (-)NCBICelera
Cytogenetic Map13q21NCBI
MR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381181,033,387 - 181,061,938 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1181,033,374 - 181,061,938 (+)Ensemblhg38GRCh38
GRCh371181,002,523 - 181,031,074 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361179,269,762 - 179,291,256 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341177,734,795 - 177,756,290NCBI
Celera1154,109,484 - 154,137,989 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1152,233,302 - 152,261,856 (+)NCBIHuRef
CHM1_11182,425,213 - 182,453,711 (+)NCBICHM1_1
T2T-CHM13v2.01180,388,622 - 180,417,159 (+)NCBIT2T-CHM13v2.0
Mr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,003,620 - 155,022,560 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,003,023 - 155,022,560 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381155,127,874 - 155,146,814 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,127,277 - 155,146,814 (-)Ensemblmm10GRCm38
MGSCv371156,975,008 - 156,993,910 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361156,890,096 - 156,909,001 (-)NCBIMGSCv36mm8
Celera1157,557,055 - 157,575,953 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map166.45NCBI
LOC102013688
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540620,098,538 - 20,125,057 (+)Ensembl
ChiLan1.0NW_00495540620,098,544 - 20,117,065 (+)NCBIChiLan1.0ChiLan1.0
LOC100972084
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2168,714,856 - 68,738,040 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,368,323 - 68,406,516 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,510,588 - 156,538,447 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,178,106 - 160,205,076 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1160,178,106 - 160,198,420 (+)EnsemblpanPan2panpan1.1
MR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1714,521,735 - 14,531,296 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha714,099,261 - 14,106,689 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0714,247,973 - 14,255,396 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1714,159,221 - 14,166,661 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0714,265,642 - 14,273,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0714,389,587 - 14,397,005 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101972633
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934490,479,169 - 90,501,203 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364818,327,690 - 8,347,960 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364818,325,918 - 8,347,941 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9122,592,532 - 122,609,022 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19122,592,510 - 122,611,462 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29134,628,625 - 134,642,871 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC101700189
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247711,275,302 - 1,293,552 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247711,275,364 - 1,298,967 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
LOC116911665
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11034,547,868 - 34,565,381 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mr1
182 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:169
Count of miRNA genes:95
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000004694
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 158 89 88 57 92 57 6 351 192 11 137 78 92 31 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000004694   ⟹   ENSRNOP00000004694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1369,850,420 - 69,868,305 (-)Ensembl
mRatBN7.2 Ensembl1367,300,103 - 67,317,970 (-)Ensembl
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103270   ⟹   ENSRNOP00000097744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1369,852,167 - 69,868,283 (-)Ensembl
mRatBN7.2 Ensembl1367,299,585 - 67,317,966 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000139053   ⟹   ENSRNOP00000110330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1369,853,142 - 69,868,502 (-)Ensembl
RefSeq Acc Id: NM_001100635   ⟹   NP_001094105
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81369,850,420 - 69,868,166 (-)NCBI
mRatBN7.21367,300,103 - 67,317,850 (-)NCBI
Rnor_6.01372,771,992 - 72,789,738 (-)NCBI
Rnor_5.01377,707,537 - 77,725,396 (-)NCBI
RGSC_v3.41370,089,637 - 70,107,384 (-)RGD
Celera1367,175,718 - 67,193,248 (-)RGD
Sequence:
RefSeq Acc Id: XR_005492204
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81369,850,858 - 69,868,302 (-)NCBI
mRatBN7.21367,298,362 - 67,317,985 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001094105 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA74305 (Get FASTA)   NCBI Sequence Viewer  
  EDM09513 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004694
GenBank Protein O19477 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001094105   ⟸   NM_001100635
- Peptide Label: precursor
- UniProtKB: O19477 (UniProtKB/Swiss-Prot),   A0A0H2UHB9 (UniProtKB/TrEMBL),   A6ICY4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004694   ⟸   ENSRNOT00000004694
Ensembl Acc Id: ENSRNOP00000097744   ⟸   ENSRNOT00000103270
Ensembl Acc Id: ENSRNOP00000110330   ⟸   ENSRNOT00000139053
Protein Domains
Ig-like   Ig-like C1-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O19477-F1-model_v2 AlphaFold O19477 1-343 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698904
Promoter ID:EPDNEW_R9429
Type:multiple initiation site
Name:Mr1_1
Description:major histocompatibility complex, class I-related
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01372,789,848 - 72,789,908EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593291 AgrOrtholog
BioCyc Gene G2FUF-17849 BioCyc
Ensembl Genes ENSRNOG00000003522 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000004694 ENTREZGENE
  ENSRNOT00000103270 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.30.500.10 UniProtKB/Swiss-Prot
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig/MHC_CS UniProtKB/Swiss-Prot
  Ig_C1-set UniProtKB/Swiss-Prot
  MHC_class-I_related UniProtKB/Swiss-Prot
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot
  MHC_I_a_a1/a2 UniProtKB/Swiss-Prot
KEGG Report rno:25119 UniProtKB/Swiss-Prot
NCBI Gene 25119 ENTREZGENE
PANTHER MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RELATED GENE PROTEIN UniProtKB/Swiss-Prot
  MHC CLASS I-RELATED UniProtKB/Swiss-Prot
Pfam C1-set UniProtKB/Swiss-Prot
  MHC_I UniProtKB/Swiss-Prot
PhenoGen Mr1 PhenoGen
PRINTS MHCCLASSI UniProtKB/Swiss-Prot
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  IG_MHC UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003522 RatGTEx
SMART IGc1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF54452 UniProtKB/Swiss-Prot
UniProt A0A0H2UHB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATJ3_RAT UniProtKB/TrEMBL
  A0ABK0M058_RAT UniProtKB/TrEMBL
  A6ICY4 ENTREZGENE, UniProtKB/TrEMBL
  HMR1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Mr1  major histocompatibility complex, class I-related  Hlals  MHC class I-like sequence  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   MHC class I-like sequence  Hlals  MHC class I-like sequence (mapped)  Name updated 737654 APPROVED
2007-04-11 Hlals  MHC class I-like sequence (mapped)  Hlals_mapped  MHC class I-like sequence (mapped)  Data merged from RGD:2799 737654 APPROVED
2006-11-20 Hlals  MHC class I-like sequence (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Hlals_mapped  MHC class I-like sequence (mapped)      Symbol and Name updated 1556543 APPROVED
2002-11-06 Hlals  MHC class I-like sequence    MHC class I-related gene  Name updated 625702 APPROVED
2002-06-10 Hlals  MHC class I-related gene      Symbol and Name status set to approved 70586 APPROVED
2001-06-12 Mr1  MHC class I-related gene      Symbol withdrawn, duplicate of Hlals (RGD:2799) 62408 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_domains contains beta2-microglobulin and CD8 contact sites 1300055
gene_other single copy gene 1300055