Mr1 (major histocompatibility complex, class I-related) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mr1 (major histocompatibility complex, class I-related) Rattus norvegicus
Analyze
Symbol: Mr1
Name: major histocompatibility complex, class I-related
RGD ID: 1593291
Description: Predicted to enable T cell receptor binding activity and beta-2-microglobulin binding activity. Predicted to be involved in several processes, including T cell differentiation in thymus; defense response to Gram-positive bacterium; and positive regulation of T cell mediated cytotoxicity directed against tumor cell target. Predicted to act upstream of or within defense response to Gram-negative bacterium. Predicted to be located in endoplasmic reticulum membrane; endosome membrane; and plasma membrane. Predicted to be part of MHC class I protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MR1 (major histocompatibility complex, class I-related); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: histocompatibility-2 complex class 1-like sequence; Hlals; Hlals_mapped; major histocompatibility complex class I-related gene protein; MHC class I-like sequence; MHC class I-like sequence (mapped); MHC class I-related; MHC class I-related gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,850,420 - 69,868,302 (-)NCBIGRCr8
mRatBN7.21367,298,362 - 67,317,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,299,585 - 67,317,970 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,885,111 - 69,903,051 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,198,901 - 71,216,775 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,459,561 - 68,477,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,771,992 - 72,789,861 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,707,537 - 77,725,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,089,637 - 70,107,384 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1367,175,718 - 67,193,248 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
acyclovir  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bupropion  (ISO)
cadmium dichloride  (ISO)
camptothecin  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
cocaine  (EXP)
corosolic acid  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gefitinib  (ISO)
glyphosate  (EXP)
hydrochlorothiazide  (ISO)
ifosfamide  (ISO)
iopromide  (ISO)
lincomycin  (ISO)
mefenamic acid  (ISO)
methyl methanesulfonate  (ISO)
minocycline  (ISO)
nickel atom  (ISO)
norfloxacin  (ISO)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
piperacillin  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
propanal  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
Repaglinide  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rofecoxib  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfasalazine  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9553154   PMID:12137932   PMID:20581831   PMID:21190736   PMID:26795251   PMID:27043408   PMID:27527800   PMID:31959982  


Genomics

Comparative Map Data
Mr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,850,420 - 69,868,302 (-)NCBIGRCr8
mRatBN7.21367,298,362 - 67,317,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,299,585 - 67,317,970 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,885,111 - 69,903,051 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,198,901 - 71,216,775 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,459,561 - 68,477,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,771,992 - 72,789,861 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,707,537 - 77,725,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,089,637 - 70,107,384 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1367,175,718 - 67,193,248 (-)NCBICelera
Cytogenetic Map13q21NCBI
MR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381181,033,387 - 181,061,938 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1181,033,374 - 181,061,938 (+)EnsemblGRCh38hg38GRCh38
GRCh371181,002,523 - 181,031,074 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361179,269,762 - 179,291,256 (+)NCBINCBI36Build 36hg18NCBI36
Build 341177,734,795 - 177,756,290NCBI
Celera1154,109,484 - 154,137,989 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1152,233,302 - 152,261,856 (+)NCBIHuRef
CHM1_11182,425,213 - 182,453,711 (+)NCBICHM1_1
T2T-CHM13v2.01180,388,622 - 180,417,159 (+)NCBIT2T-CHM13v2.0
Mr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,003,620 - 155,022,560 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,003,023 - 155,022,560 (-)EnsemblGRCm39 Ensembl
GRCm381155,127,874 - 155,146,814 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,127,277 - 155,146,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv371156,975,008 - 156,993,910 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361156,890,096 - 156,909,001 (-)NCBIMGSCv36mm8
Celera1157,557,055 - 157,575,953 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map166.45NCBI
LOC102013688
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540620,098,538 - 20,125,057 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540620,098,544 - 20,117,065 (+)NCBIChiLan1.0ChiLan1.0
LOC100972084
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2168,714,856 - 68,738,040 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,368,323 - 68,406,516 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,510,588 - 156,538,447 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,178,106 - 160,205,076 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1160,178,106 - 160,198,420 (+)Ensemblpanpan1.1panPan2
MR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1714,521,735 - 14,531,296 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha714,099,261 - 14,106,689 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0714,247,973 - 14,255,396 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1714,159,221 - 14,166,661 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0714,265,642 - 14,273,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0714,389,587 - 14,397,005 (+)NCBIUU_Cfam_GSD_1.0
LOC101972633
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934490,479,169 - 90,501,203 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364818,327,690 - 8,347,960 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364818,325,918 - 8,347,941 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9122,592,532 - 122,609,022 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19122,592,510 - 122,611,462 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29134,628,625 - 134,642,871 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC101700189
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247711,275,302 - 1,293,552 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247711,275,364 - 1,298,967 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mr1
78 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:169
Count of miRNA genes:95
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000004694
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)135949252277046890Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1366451204106807694Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 89 88 57 25 57 6 216 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000004694   ⟹   ENSRNOP00000004694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1367,300,103 - 67,317,970 (-)Ensembl
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103270   ⟹   ENSRNOP00000097744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1367,299,585 - 67,317,966 (-)Ensembl
RefSeq Acc Id: NM_001100635   ⟹   NP_001094105
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81369,850,420 - 69,868,166 (-)NCBI
mRatBN7.21367,300,103 - 67,317,850 (-)NCBI
Rnor_6.01372,771,992 - 72,789,738 (-)NCBI
Rnor_5.01377,707,537 - 77,725,396 (-)NCBI
RGSC_v3.41370,089,637 - 70,107,384 (-)RGD
Celera1367,175,718 - 67,193,248 (-)RGD
Sequence:
RefSeq Acc Id: XR_005492204
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81369,850,858 - 69,868,302 (-)NCBI
mRatBN7.21367,298,362 - 67,317,985 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001094105 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA74305 (Get FASTA)   NCBI Sequence Viewer  
  EDM09513 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004694.4
  ENSRNOP00000097744.1
GenBank Protein O19477 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001094105   ⟸   NM_001100635
- Peptide Label: precursor
- UniProtKB: O19477 (UniProtKB/Swiss-Prot),   A0A0H2UHB9 (UniProtKB/TrEMBL),   A6ICY4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004694   ⟸   ENSRNOT00000004694
Ensembl Acc Id: ENSRNOP00000097744   ⟸   ENSRNOT00000103270
Protein Domains
Ig-like   Ig-like C1-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O19477-F1-model_v2 AlphaFold O19477 1-343 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698904
Promoter ID:EPDNEW_R9429
Type:multiple initiation site
Name:Mr1_1
Description:major histocompatibility complex, class I-related
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01372,789,848 - 72,789,908EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593291 AgrOrtholog
BioCyc Gene G2FUF-17849 BioCyc
Ensembl Genes ENSRNOG00000003522 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004694.6 UniProtKB/TrEMBL
  ENSRNOT00000103270.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_class-I_related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25119 UniProtKB/Swiss-Prot
NCBI Gene 25119 ENTREZGENE
PANTHER MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RELATED GENE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mr1 PhenoGen
PRINTS MHCCLASSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003522 RatGTEx
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0H2UHB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATJ3_RAT UniProtKB/TrEMBL
  A6ICY4 ENTREZGENE, UniProtKB/TrEMBL
  HMR1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Mr1  major histocompatibility complex, class I-related  Hlals  MHC class I-like sequence  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   MHC class I-like sequence  Hlals  MHC class I-like sequence (mapped)  Name updated 737654 APPROVED
2007-04-11 Hlals  MHC class I-like sequence (mapped)  Hlals_mapped  MHC class I-like sequence (mapped)  Data merged from RGD:2799 737654 APPROVED
2006-11-20 Hlals  MHC class I-like sequence (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Hlals_mapped  MHC class I-like sequence (mapped)      Symbol and Name updated 1556543 APPROVED
2002-11-06 Hlals  MHC class I-like sequence    MHC class I-related gene  Name updated 625702 APPROVED
2002-06-10 Hlals  MHC class I-related gene      Symbol and Name status set to approved 70586 APPROVED
2001-06-12 Mr1  MHC class I-related gene      Symbol withdrawn, duplicate of Hlals (RGD:2799) 62408 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_domains contains beta2-microglobulin and CD8 contact sites 1300055
gene_other single copy gene 1300055