Mr1 (major histocompatibility complex, class I-related) - Rat Genome Database

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Gene: Mr1 (major histocompatibility complex, class I-related) Rattus norvegicus
Analyze
Symbol: Mr1
Name: major histocompatibility complex, class I-related
RGD ID: 1593291
Description: Predicted to enable T cell receptor binding activity and beta-2-microglobulin binding activity. Predicted to be involved in several processes, including T cell differentiation in thymus; defense response to Gram-positive bacterium; and positive regulation of T cell mediated cytotoxicity directed against tumor cell target. Predicted to act upstream of or within defense response to Gram-negative bacterium. Predicted to be located in endoplasmic reticulum membrane; endosome membrane; and plasma membrane. Predicted to be part of MHC class I protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MR1 (major histocompatibility complex, class I-related); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: histocompatibility-2 complex class 1-like sequence; Hlals; Hlals_mapped; major histocompatibility complex class I-related gene protein; MHC class I-like sequence; MHC class I-like sequence (mapped); MHC class I-related; MHC class I-related gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,850,420 - 69,868,302 (-)NCBIGRCr8
mRatBN7.21367,298,362 - 67,317,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,299,585 - 67,317,970 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,885,111 - 69,903,051 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,198,901 - 71,216,775 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,459,561 - 68,477,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,771,992 - 72,789,861 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,707,537 - 77,725,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,089,637 - 70,107,384 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1367,175,718 - 67,193,248 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mr1Rat1q24 Deletion Syndrome  ISOMR1 (Homo sapiens)8554872ClinVar Annotator: match by term: 1q24q25 microdeletion syndromeClinVarPMID:21548129 more ...
Mr1Ratautosomal recessive chronic granulomatous disease 2  ISOMR1 (Homo sapiens)8554872ClinVar Annotator: match by term: Granulomatous disease more ...ClinVarPMID:28492532
Mr1Ratgastrointestinal stromal tumor  ISOMR1 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Mr1Ratparathyroid carcinoma  ISOMR1 (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532

1 to 20 of 114 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mr1Rat(-)-alpha-phellandrene increases expressionISOMR1 (Homo sapiens)6480464alpha phellandrene results in increased expression of MR1 mRNACTDPMID:25075043
Mr1Rat(-)-demecolcine increases expressionISOMR1 (Homo sapiens)6480464Demecolcine results in increased expression of MR1 mRNACTDPMID:23649840
Mr1Rat1,2-dimethylhydrazine increases expressionISOMr1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of MR1 mRNACTDPMID:22206623
Mr1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOMR1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of MR1 mRNACTDPMID:20106945 and PMID:21632981
Mr1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MR1 mRNACTDPMID:33387578
Mr1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOMr1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of MR1 mRNACTDPMID:25975270
Mr1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMr1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of MR1 mRNACTDPMID:21570461
Mr1Rat3,4-methylenedioxymethamphetamine decreases expressionISOMr1 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of MR1 mRNACTDPMID:26251327
Mr1Rat4,4'-sulfonyldiphenol increases expressionISOMr1 (Mus musculus)6480464bisphenol S results in increased expression of MR1 mRNACTDPMID:30951980
Mr1Rat4,4'-sulfonyldiphenol decreases expressionISOMr1 (Mus musculus)6480464bisphenol S results in decreased expression of MR1 mRNACTDPMID:39298647
Mr1Rat5-fluorouracil increases expressionISOMR1 (Homo sapiens)6480464Fluorouracil results in increased expression of MR1 mRNACTDPMID:16101138
Mr1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of MR1 mRNACTDPMID:25825206
Mr1Rat7,12-dimethyltetraphene increases expressionISOMR1 (Homo sapiens)64804649 more ...CTDPMID:21527772
Mr1Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of MR1 mRNACTDPMID:31881176
Mr1Ratactinomycin D multiple interactionsISOMR1 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased expression of MR1 mRNACTDPMID:38460933
Mr1Ratactinomycin D increases expressionISOMR1 (Homo sapiens)6480464Dactinomycin results in increased expression of MR1 mRNACTDPMID:38460933
Mr1Ratacyclovir affects expressionISOMR1 (Homo sapiens)6480464Acyclovir affects the expression of MR1 mRNACTDPMID:25811541
Mr1Rataflatoxin B1 increases expressionISOMR1 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of MR1 mRNA and Aflatoxin B1 results in increased expression of MR1 proteinCTDPMID:21527772 more ...
Mr1Rataflatoxin B1 increases methylationISOMR1 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of MR1 geneCTDPMID:27153756
Mr1Rataflatoxin B1 affects expressionISOMR1 (Homo sapiens)6480464Aflatoxin B1 affects the expression of MR1 proteinCTDPMID:20106945

1 to 20 of 114 rows

Biological Process
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mr1Ratantigen processing and presentation of exogenous antigen involved_inISOMR1 (Homo sapiens)1624291 PMID:27043408RGDPMID:27043408
Mr1Ratantigen processing and presentation of exogenous antigen involved_inIEAUniProtKB:Q95460 and ensembl:ENSP000003565521600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratantigen processing and presentation of peptide antigen via MHC class I involved_inIEAUniProtKB-KW:KW-04901600115GO_REF:0000043UniProtGO_REF:0000043
Mr1Ratdefense response to Gram-negative bacterium involved_inISOMR1 (Homo sapiens)1624291 PMID:20581831RGDPMID:20581831
Mr1Ratdefense response to Gram-negative bacterium acts_upstream_of_or_withinIEAUniProtKB:Q8HWB0 and ensembl:ENSMUSP000000277441600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratdefense response to Gram-negative bacterium acts_upstream_of_or_withinISOMr1 (Mus musculus)1624291MGI:3664578 PMID:21190736RGDPMID:21190736
Mr1Ratdefense response to Gram-negative bacterium involved_inISOMr1 (Mus musculus)1624291 PMID:20581831RGDPMID:20581831
Mr1Ratdefense response to Gram-negative bacterium involved_inIEAUniProtKB:Q95460 and ensembl:ENSP000003565521600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratdefense response to Gram-positive bacterium involved_inIEAUniProtKB:Q95460 and ensembl:ENSP000003565521600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratdefense response to Gram-positive bacterium involved_inISOMR1 (Homo sapiens)1624291 PMID:27527800RGDPMID:27527800
Mr1Ratimmune response involved_inIBAMGI:1195463 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mr1Ratimmune system process involved_inIEAUniProtKB-KW:KW-03911600115GO_REF:0000043UniProtGO_REF:0000043
Mr1Ratinnate immune response involved_inIEAUniProtKB-KW:KW-03991600115GO_REF:0000043UniProtGO_REF:0000043
Mr1Ratpositive regulation of T cell mediated cytotoxicity directed against tumor cell target involved_inIEAUniProtKB:Q95460 and ensembl:ENSP000003565521600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratpositive regulation of T cell mediated cytotoxicity directed against tumor cell target involved_inISOMR1 (Homo sapiens)1624291 PMID:31959982RGDPMID:31959982
Mr1RatT cell differentiation in thymus involved_inIEAUniProtKB:Q8HWB0 and ensembl:ENSMUSP000000277441600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1RatT cell differentiation in thymus involved_inISOMr1 (Mus musculus)1624291 PMID:12634786RGDPMID:12634786
1 to 17 of 17 rows

Cellular Component
1 to 20 of 25 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mr1Ratearly endosome membrane located_inIEAUniProtKB:Q95460 and ensembl:ENSP000003565521600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratearly endosome membrane located_inIEAUniProtKB-SubCell:SL-00931600115GO_REF:0000044UniProtGO_REF:0000044
Mr1Ratearly endosome membrane located_inISOMR1 (Homo sapiens)1624291 PMID:27043408RGDPMID:27043408
Mr1Ratendoplasmic reticulum located_inISOMR1 (Homo sapiens)1624291 PMID:21190736RGDPMID:21190736
Mr1Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Mr1Ratendoplasmic reticulum located_inIEAUniProtKB:Q95460 and ensembl:ENSP000003565521600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratendoplasmic reticulum membrane located_inIEAUniProtKB:Q95460 and ensembl:ENSP000003565521600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Mr1Ratendoplasmic reticulum membrane located_inISOMR1 (Homo sapiens)1624291 PMID:27043408RGDPMID:27043408
Mr1Ratendosome located_inIEAUniProtKB-KW:KW-09671600115GO_REF:0000043UniProtGO_REF:0000043
Mr1Ratexternal side of plasma membrane is_active_inIBAMGI:107674 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mr1Ratextracellular space is_active_inIBAMGI:95929 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mr1RatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
Mr1RatGolgi membrane located_inIEAUniProtKB-SubCell:SL-01341600115GO_REF:0000044UniProtGO_REF:0000044
Mr1Ratlate endosome membrane located_inISOMR1 (Homo sapiens)1624291 PMID:27043408RGDPMID:27043408
Mr1Ratlate endosome membrane located_inIEAUniProtKB-SubCell:SL-01511600115GO_REF:0000044UniProtGO_REF:0000044
Mr1Ratlate endosome membrane located_inIEAUniProtKB:Q95460 and ensembl:ENSP000003565521600115GO_REF:0000107EnsemblGO_REF:0000107
Mr1Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Mr1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Mr1RatMHC class I protein complex part_ofIEAUniProtKB-KW:KW-04901600115GO_REF:0000043UniProtGO_REF:0000043
1 to 20 of 25 rows

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9553154   PMID:12137932   PMID:20581831   PMID:21190736   PMID:26795251   PMID:27043408   PMID:27527800   PMID:31959982  



Mr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,850,420 - 69,868,302 (-)NCBIGRCr8
mRatBN7.21367,298,362 - 67,317,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,299,585 - 67,317,970 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,885,111 - 69,903,051 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,198,901 - 71,216,775 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,459,561 - 68,477,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,771,992 - 72,789,861 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,707,537 - 77,725,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,089,637 - 70,107,384 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1367,175,718 - 67,193,248 (-)NCBICelera
Cytogenetic Map13q21NCBI
MR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381181,033,387 - 181,061,938 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1181,033,374 - 181,061,938 (+)EnsemblGRCh38hg38GRCh38
GRCh371181,002,523 - 181,031,074 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361179,269,762 - 179,291,256 (+)NCBINCBI36Build 36hg18NCBI36
Build 341177,734,795 - 177,756,290NCBI
Celera1154,109,484 - 154,137,989 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1152,233,302 - 152,261,856 (+)NCBIHuRef
CHM1_11182,425,213 - 182,453,711 (+)NCBICHM1_1
T2T-CHM13v2.01180,388,622 - 180,417,159 (+)NCBIT2T-CHM13v2.0
Mr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,003,620 - 155,022,560 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,003,023 - 155,022,560 (-)EnsemblGRCm39 Ensembl
GRCm381155,127,874 - 155,146,814 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,127,277 - 155,146,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv371156,975,008 - 156,993,910 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361156,890,096 - 156,909,001 (-)NCBIMGSCv36mm8
Celera1157,557,055 - 157,575,953 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map166.45NCBI
LOC102013688
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540620,098,538 - 20,125,057 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540620,098,544 - 20,117,065 (+)NCBIChiLan1.0ChiLan1.0
LOC100972084
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2168,714,856 - 68,738,040 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,368,323 - 68,406,516 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,510,588 - 156,538,447 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,178,106 - 160,205,076 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1160,178,106 - 160,198,420 (+)Ensemblpanpan1.1panPan2
MR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1714,521,735 - 14,531,296 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha714,099,261 - 14,106,689 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0714,247,973 - 14,255,396 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1714,159,221 - 14,166,661 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0714,265,642 - 14,273,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0714,389,587 - 14,397,005 (+)NCBIUU_Cfam_GSD_1.0
LOC101972633
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934490,479,169 - 90,501,203 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364818,327,690 - 8,347,960 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364818,325,918 - 8,347,941 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9122,592,532 - 122,609,022 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19122,592,510 - 122,611,462 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29134,628,625 - 134,642,871 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC101700189
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247711,275,302 - 1,293,552 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247711,275,364 - 1,298,967 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Mr1
78 total Variants

Predicted Target Of
Summary Value
Count of predictions:169
Count of miRNA genes:95
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000004694
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat

1 to 10 of 33 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 89 88 57 25 57 6 216 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000004694   ⟹   ENSRNOP00000004694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1367,300,103 - 67,317,970 (-)Ensembl
Rnor_6.0 Ensembl1372,771,984 - 72,789,841 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103270   ⟹   ENSRNOP00000097744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1367,299,585 - 67,317,966 (-)Ensembl
RefSeq Acc Id: NM_001100635   ⟹   NP_001094105
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81369,850,420 - 69,868,166 (-)NCBI
mRatBN7.21367,300,103 - 67,317,850 (-)NCBI
Rnor_6.01372,771,992 - 72,789,738 (-)NCBI
Rnor_5.01377,707,537 - 77,725,396 (-)NCBI
RGSC_v3.41370,089,637 - 70,107,384 (-)RGD
Celera1367,175,718 - 67,193,248 (-)RGD
Sequence:
RefSeq Acc Id: XR_005492204
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81369,850,858 - 69,868,302 (-)NCBI
mRatBN7.21367,298,362 - 67,317,985 (-)NCBI
Protein RefSeqs NP_001094105 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA74305 (Get FASTA)   NCBI Sequence Viewer  
  EDM09513 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004694
GenBank Protein O19477 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001094105   ⟸   NM_001100635
- Peptide Label: precursor
- UniProtKB: O19477 (UniProtKB/Swiss-Prot),   A0A0H2UHB9 (UniProtKB/TrEMBL),   A6ICY4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004694   ⟸   ENSRNOT00000004694
Ensembl Acc Id: ENSRNOP00000097744   ⟸   ENSRNOT00000103270
Ig-like   Ig-like C1-type

Name Modeler Protein Id AA Range Protein Structure
AF-O19477-F1-model_v2 AlphaFold O19477 1-343 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13698904
Promoter ID:EPDNEW_R9429
Type:multiple initiation site
Name:Mr1_1
Description:major histocompatibility complex, class I-related
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01372,789,848 - 72,789,908EPDNEW


1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-17849 BioCyc
Ensembl Genes ENSRNOG00000003522 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000004694 ENTREZGENE
  ENSRNOT00000103270 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.30.500.10 UniProtKB/Swiss-Prot
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig/MHC_CS UniProtKB/Swiss-Prot
  Ig_C1-set UniProtKB/Swiss-Prot
  MHC_class-I_related UniProtKB/Swiss-Prot
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot
  MHC_I_a_a1/a2 UniProtKB/Swiss-Prot
KEGG Report rno:25119 UniProtKB/Swiss-Prot
NCBI Gene 25119 ENTREZGENE
PANTHER MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RELATED GENE PROTEIN UniProtKB/Swiss-Prot
  MHC CLASS I-RELATED UniProtKB/Swiss-Prot
Pfam C1-set UniProtKB/Swiss-Prot
  MHC_I UniProtKB/Swiss-Prot
PhenoGen Mr1 PhenoGen
PRINTS MHCCLASSI UniProtKB/Swiss-Prot
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  IG_MHC UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003522 RatGTEx
SMART IGc1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF54452 UniProtKB/Swiss-Prot
UniProt A0A0H2UHB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATJ3_RAT UniProtKB/TrEMBL
  A6ICY4 ENTREZGENE, UniProtKB/TrEMBL
  HMR1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Mr1  major histocompatibility complex, class I-related  Hlals  MHC class I-like sequence  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   MHC class I-like sequence  Hlals  MHC class I-like sequence (mapped)  Name updated 737654 APPROVED
2007-04-11 Hlals  MHC class I-like sequence (mapped)  Hlals_mapped  MHC class I-like sequence (mapped)  Data merged from RGD:2799 737654 APPROVED
2006-11-20 Hlals  MHC class I-like sequence (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Hlals_mapped  MHC class I-like sequence (mapped)      Symbol and Name updated 1556543 APPROVED
2002-11-06 Hlals  MHC class I-like sequence    MHC class I-related gene  Name updated 625702 APPROVED
2002-06-10 Hlals  MHC class I-related gene      Symbol and Name status set to approved 70586 APPROVED
2001-06-12 Mr1  MHC class I-related gene      Symbol withdrawn, duplicate of Hlals (RGD:2799) 62408 WITHDRAWN

Note Type Note Reference
gene_domains contains beta2-microglobulin and CD8 contact sites 1300055
gene_other single copy gene 1300055