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Gene: Teddm1a (transmembrane epididymal protein 1A) Rattus norvegicus

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Symbol:

Teddm1a

Name:

transmembrane epididymal protein 1A

RGD ID:

1593124

Description:

Predicted to be located in membrane. Orthologous to human TEDDM1 (transmembrane epididymal protein 1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Teddm1; transmembrane epididymal protein 1

RGD Orthologs

Mouse

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Teddm1a (transmembrane epididymal protein 1A)	RGD	RGD
Other homologs ²
Homo sapiens (human):	TEDDM1 (transmembrane epididymal protein 1)	HGNC	Ensembl, Panther
Homo sapiens (human):	GLUL (glutamate-ammonia ligase)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	TEDDM1 (transmembrane epididymal protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Teddm1a (transmembrane epididymal protein 1A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	teddm1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	teddm1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	68,567,889 - 68,569,191 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	68,567,889 - 68,569,191 (+)	Ensembl				GRCr8
mRatBN7.2	13	66,017,448 - 66,018,750 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	66,017,493 - 66,018,750 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	68,619,434 - 68,620,691 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	69,908,578 - 69,909,835 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	67,165,528 - 67,166,785 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	71,322,759 - 71,324,016 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	71,322,759 - 71,324,016 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	76,286,178 - 76,287,435 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	13	65,914,741 - 65,915,998 (+)	NCBI		Celera
Cytogenetic Map	13	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Teddm1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	68,567,889 - 68,569,191 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	68,567,889 - 68,569,191 (+)	Ensembl				GRCr8
mRatBN7.2	13	66,017,448 - 66,018,750 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	66,017,493 - 66,018,750 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	68,619,434 - 68,620,691 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	69,908,578 - 69,909,835 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	67,165,528 - 67,166,785 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	71,322,759 - 71,324,016 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	71,322,759 - 71,324,016 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	76,286,178 - 76,287,435 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	13	65,914,741 - 65,915,998 (+)	NCBI		Celera
Cytogenetic Map	13	q21	NCBI

Teddm1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	153,767,481 - 153,768,809 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	153,767,488 - 153,768,804 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	153,891,646 - 153,893,060 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	153,891,742 - 153,893,058 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	155,738,776 - 155,740,190 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	155,654,010 - 155,655,276 (+)	NCBI		MGSCv36	mm8
Celera	1	156,324,765 - 156,326,179 (+)	NCBI		Celera
Cytogenetic Map	1	G3	NCBI
cM Map	1	65.43	NCBI

Variants

Variants in Teddm1a
4 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	54
Count of miRNA genes:	52
Interacting mature miRNAs:	52
Transcripts:	ENSRNOT00000071815
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	48749814	87285480	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	24853925	69853925	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	39968211	83286298	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37087983	82087983	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	40983585	85983585	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
738026	Lnnr5	Liver neoplastic nodule remodeling QTL 5	3.29		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	62424592	88113509	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	26244808	71244808	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	33794096	78794096	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	34834947	79834947	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	39814726	84814726	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	39968211	84968211	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	26244808	71244808	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	38286298	83286298	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system	sensory system	visual system
1	1	5	4	7	4	4	4	10	5	5	22	3	1	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001039915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ515382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000071815 ⟹ ENSRNOP00000064589

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	68,567,889 - 68,569,191 (+)	Ensembl
mRatBN7.2 Ensembl	13	66,017,493 - 66,018,750 (+)	Ensembl
Rnor_6.0 Ensembl	13	71,322,759 - 71,324,016 (+)	Ensembl

RefSeq Acc Id:

NM_001039915 ⟹ NP_001035004

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,567,889 - 68,569,191 (+)	NCBI
mRatBN7.2	13	66,017,448 - 66,018,750 (+)	NCBI
Rnor_6.0	13	71,322,759 - 71,324,016 (+)	NCBI
Rnor_5.0	13	76,286,178 - 76,287,435 (+)	NCBI
Celera	13	65,914,741 - 65,915,998 (+)	RGD

Sequence:

show sequence

ATGGGAGACTTTATTGGCCATATATCTCCAGGTTTGTTTCTGGTCTTCTATGGTCTGTATCAAG
CAATAATAGTCTCCAGAGCTCTGATACTCAACGACTCTCTCCTGTATCCTTCCTACCTTTCCAA
GAATAAGGGGAAATGGGCCAGGCTGTGGCAAATAGCTCATGCAGGCTGGTTGAAGGTTGTGAGT
GGCTCCCTCTTGATAGTTTATGAGCTCAACTGTGTTGATGAAGGGCTGACATTTATGACCAAAA
TGATACCACCAAGGTTTATGTACCCCAAGGAGTGGCAGCACCTCACCATGTTCATCCTCCTCAC
CCTTGATGGCTGTGTGGAAGTGGTGAGCAGGAGTGTGCTGAGGCAGAGGTTGGTGCTTCTAGAA
AGAGGCGCCACGGTGCTGGGTGTCTACGTGCTTCTGCTGCTGCTGGTGTCCCACGTTAAAGACT
CATCTGGGGTGGAGCTGCAGGTTCACTCTCTCCTCATCTTGGTGGTATTCCTGCTGATGCTGGT
GTTGACCGCCGAGCTGTGGGCTCCTGAGATGGTCCACCTCTGGGTGATAGAGACCTTTCTGTTC
CTGACGATGGGCTCATGGCTGATGCAGGCAGCCTTCATCCTGTTTAGACCAGTCTCCGGCTTCC
CGTGGGAGGATGATGACATCAGTAACATCATGCTTGTCACCACGTTCTTCTGCTGGCACGTGAT
GATCAACGCCTTATGCATGCTGGGAATCTATGGCATCTCTTCCTTTTGGCACCGTTGTTACAGA
ACCGGCTTGATGCCGATGGGGTCCAAGGAAGTGCTGTATCACAAGAGCTCTGAAGGAACCTTCT
ACAAGCTGCTGCAGAAGGCAGAGCAGCAGGACAGAGATGACCAGGCTCCTCTCCTTTCAAAGAG
CTCTCCCTGTGACAGAGCCTAGAATACCATGCCATCTTCCTCCTGTGGGCTCTCCTGGGCACTT
GCAATGTACCTTTTGCTCCCCGGTGAAGGTAATGGCCCTGGAGGATGGTAGTTGGTTCCCTGTC
AGCCATTGCACTCCCTGTCTCTGAGCCTGCAGTTAATGCTAAGGAGAAGAGGCCCCAGAATGAT
GGGACTTAAGAAGAGGATGGGAAGACTGGGGGATAGGTTCACACACAAGCAAAACCGGTGGTGG
AGGGTGTGTGTGAAGCAGAATGGTGTTGGAGAGAGGAGCCCAGAATTCTGTACTCAGAGCTGTT
TCTCTGAATGCTTCACCTGAGGGAATAAAGATTCCTCACAGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001035004	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAD56346	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000064589
GenBank Protein	Q8CHM9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001035004 ⟸ NM_001039915

- UniProtKB:

Q8CHM9 (UniProtKB/Swiss-Prot), M0R5C5 (UniProtKB/TrEMBL), A6ICW4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGDFIGHISPGLFLVFYGLYQAIIVSRALILNDSLLYPSYLSKNKGKWARLWQIAHAGWLKVVS
GSLLIVYELNCVDEGLTFMTKMIPPRFMYPKEWQHLTMFILLTLDGCVEVVSRSVLRQRLVLLE
RGATVLGVYVLLLLLVSHVKDSSGVELQVHSLLILVVFLLMLVLTAELWAPEMVHLWVIETFLF
LTMGSWLMQAAFILFRPVSGFPWEDDDISNIMLVTTFFCWHVMINALCMLGIYGISSFWHRCYR
TGLMPMGSKEVLYHKSSEGTFYKLLQKAEQQDRDDQAPLLSKSSPCDRA

hide sequence

Ensembl Acc Id:

ENSRNOP00000064589 ⟸ ENSRNOT00000071815

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8CHM9-F1-model_v2	AlphaFold	Q8CHM9	1-305	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698901

Promoter ID:

EPDNEW_R9426

Type:

single initiation site

Name:

Teddm1_1

Description:

transmembrane epididymal protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	71,322,711 - 71,322,771	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1593124	AgrOrtholog
BioCyc Gene	G2FUF-17870	BioCyc
Ensembl Genes	ENSRNOG00000048614	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000071815	ENTREZGENE
InterPro	DUF716	UniProtKB/Swiss-Prot
KEGG Report	rno:664710	UniProtKB/Swiss-Prot
NCBI Gene	664710	ENTREZGENE
PANTHER	TRANSMEMBRANE EPIDIDYMAL FAMILY MEMBER 3	UniProtKB/Swiss-Prot
	TRANSMEMBRANE EPIDIDYMAL PROTEIN 1A	UniProtKB/Swiss-Prot
Pfam	DUF716	UniProtKB/Swiss-Prot
PhenoGen	Teddm1a	PhenoGen
RatGTEx	ENSRNOG00000048614	RatGTEx
UniProt	A6ICW4	ENTREZGENE, UniProtKB/TrEMBL
	M0R5C5	ENTREZGENE, UniProtKB/TrEMBL
	Q8CHM9	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-07-07	Teddm1a	transmembrane epididymal protein 1A	Teddm1	transmembrane epididymal protein 1	Name and Symbol changed	629549	APPROVED
2006-11-20	Teddm1	transmembrane epididymal protein 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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