Vom2r65 (vomeronasal 2 receptor, 65) - Rat Genome Database

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Gene: Vom2r65 (vomeronasal 2 receptor, 65) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r65
Name: vomeronasal 2 receptor, 65
RGD ID: 1592357
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; indole-3-methanol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC689403; similar to vomeronasal 2, receptor, 2; vomeronasal 2 receptor 65
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81637,388 - 649,777 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1637,388 - 649,777 (+)EnsemblGRCr8
UTH_Rnor_SHR_UtxPNT010000246.1391,505 - 403,912 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01413,140 - 425,549 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0PNS010000042.1771,473 - 783,878 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1815,927 - 828,326 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1387,177 - 399,578 (+)NCBILyon_Normotensive
Lyon_Hypertensive11,854,161 - 1,866,560 (+)NCBILyon_Hypertensive
F344_StmMcwi145,148 - 57,551 (+)NCBIF344_StmMcwi
Rnor_6.010111,255,293 - 111,290,820 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10111,278,985 - 111,290,820 (-)Ensemblrn6Rnor6.0
Rnor_5.010110,828,455 - 110,863,982 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41444,953 - 57,338 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Cytogenetic Map10q32.3NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15057822   PMID:17382427  


Genomics

Variants

.
Variants in Vom2r65
202 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:162
Count of miRNA genes:68
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000040119, ENSRNOT00000041082, ENSRNOT00000071844, ENSRNOT00000073174
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1126564886Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1126564886Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1128483164Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
mesoderm
nervous system
reproductive system
1 5 7 2 2 2 5 2 3 13

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001099654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041082   ⟹   ENSRNOP00000040299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl10111,278,985 - 111,290,820 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000139339   ⟹   ENSRNOP00000102045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1637,388 - 649,777 (+)Ensembl
RefSeq Acc Id: NM_001099654   ⟹   NP_001093124
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81637,388 - 649,777 (+)NCBI
Dahl_SR_JrHsd1815,927 - 828,326 (-)NCBI
Lyon_Normotensive1387,177 - 399,578 (+)NCBI
Lyon_Hypertensive11,854,161 - 1,866,560 (+)NCBI
F344_StmMcwi145,148 - 57,551 (+)NCBI
Rnor_6.010111,255,293 - 111,290,820 (-)NCBI
Rnor_5.010110,828,455 - 110,863,982 (-)NCBI
RGSC_v3.41444,953 - 57,338 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001093124 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000102045
  ENSRNOP00000102045.1
  ENSRNOP00000103214.1
RefSeq Acc Id: NP_001093124   ⟸   NM_001099654
- Peptide Label: precursor
- UniProtKB: A0A8I6GC46 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000040299   ⟸   ENSRNOT00000041082
Ensembl Acc Id: ENSRNOP00000102045   ⟸   ENSRNOT00000139339

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AA85-F1-model_v2 AlphaFold D4AA85 1-658 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1592357 AgrOrtholog
Ensembl Genes ENSRNOG00000049635 Ensembl
  ENSRNOG00000076549 UniProtKB/TrEMBL
  ENSRNOG00000085486 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000139339 ENTREZGENE
  ENSRNOT00000139339.1 UniProtKB/TrEMBL
  ENSRNOT00000172050.1 UniProtKB/TrEMBL
NCBI Gene 689403 ENTREZGENE
PhenoGen Vom2r65 PhenoGen
RatGTEx ENSRNOG00000049635 RatGTEx
  ENSRNOG00000076549 RatGTEx
  ENSRNOG00000085486 RatGTEx
UniProt A0A8I6GC46 ENTREZGENE
  A0ABK0LKD9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Vom2r65  vomeronasal 2 receptor, 65  LOC681610  similar to vomeronasal 2, receptor, 2  Data merged from RGD:1592920 1643240 APPROVED
2008-07-23 Vom2r65  vomeronasal 2 receptor, 65  LOC689403  similar to vomeronasal 2, receptor, 2  Symbol and Name updated 1299863 APPROVED
2006-11-20 LOC689403  similar to vomeronasal 2, receptor, 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681610  similar to vomeronasal 2, receptor, 2      Symbol and Name status set to provisional 70820 PROVISIONAL