Rps12l7 (ribosomal protein S12-like 7) - Rat Genome Database

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Gene: Rps12l7 (ribosomal protein S12-like 7) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps12l7
Name: ribosomal protein S12-like 7
RGD ID: 1592281
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in maintenance of translational fidelity and ribosomal small subunit biogenesis. Part of cytosolic large ribosomal subunit and cytosolic small ribosomal subunit. Orthologous to human RPS12 (ribosomal protein S12).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 40S ribosomal protein S12-like; LOC689481; similar to ribosomal protein S12; small ribosomal subunit protein eS12-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8561,763,055 - 61,763,584 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2556,967,192 - 56,987,008 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl556,967,236 - 56,967,634 (-)EnsemblmRatBN7.2
Rnor_6.0558,184,883 - 58,185,386 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0562,709,248 - 62,709,740 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4559,225,609 - 59,226,007 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera555,559,383 - 55,559,886 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
Additional References at PubMed
PMID:925037   PMID:3308890   PMID:3366245  


Genomics

Variants

.
Variants in Rps12l7
4 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
4 1 2 2 12 3 2 2 5 11

Sequence


Ensembl Acc Id: ENSRNOT00000040968   ⟹   ENSRNOP00000062764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl556,967,236 - 56,967,634 (-)Ensembl
RefSeq Acc Id: XM_039110970   ⟹   XP_038966898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8561,763,055 - 61,763,584 (-)NCBI
mRatBN7.2556,967,192 - 56,987,008 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038966898 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000062764
RefSeq Acc Id: XP_038966898   ⟸   XM_039110970
- UniProtKB: P63324 (UniProtKB/Swiss-Prot),   D3ZEB8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000062764   ⟸   ENSRNOT00000040968
Protein Domains
Ribosomal protein eL8/eL30/eS12/Gadd45

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZEB8-F1-model_v2 AlphaFold D3ZEB8 1-123 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1592281 AgrOrtholog
BioCyc Gene G2FUF-41534 BioCyc
Ensembl Genes ENSRNOG00000070664 Ensembl
  ENSRNOG00000076152 ENTREZGENE
Ensembl Transcript ENSRNOT00000040968 ENTREZGENE
Gene3D-CATH 3.30.1330.30 UniProtKB/Swiss-Prot
InterPro L30e-like UniProtKB/Swiss-Prot
  Ribosomal_eS12_CS UniProtKB/Swiss-Prot
  Ribosomal_L7Ae/L30e/S12e/Gad45 UniProtKB/Swiss-Prot
  Ribosomal_S12e UniProtKB/Swiss-Prot
NCBI Gene 689481 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S12 UniProtKB/Swiss-Prot
Pfam Ribosomal_L7Ae UniProtKB/Swiss-Prot
PhenoGen Rps12l7 PhenoGen
PRINTS RIBSOMALS12E UniProtKB/Swiss-Prot
PROSITE RIBOSOMAL_S12E UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000070664 RatGTEx
  ENSRNOG00000076152 RatGTEx
Superfamily-SCOP L30e-like UniProtKB/Swiss-Prot
UniProt D3ZEB8 ENTREZGENE, UniProtKB/TrEMBL
  P63324 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P09388 UniProtKB/Swiss-Prot
  P12728 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rps12l7  ribosomal protein S12-like 7  LOC689481  similar to ribosomal protein S12  Symbol and Name Changed 1299863 APPROVED
2008-01-09 LOC689481  similar to ribosomal protein S12  LOC683075  similar to ribosomal protein S12  Data merged from RGD:1591533 1643240 APPROVED
2006-11-20 LOC689481  similar to ribosomal protein S12      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC683075  similar to ribosomal protein S12      Symbol and Name status set to provisional 70820 PROVISIONAL