Impact (impact RWD domain protein) - Rat Genome Database

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Gene: Impact (impact RWD domain protein) Rattus norvegicus
Analyze
Symbol: Impact
Name: impact RWD domain protein
RGD ID: 1591977
Description: Predicted to enable actin binding activity; protein sequestering activity; and ribosome binding activity. Predicted to be involved in several processes, including GCN2-mediated signaling; cellular response to amino acid starvation; and regulation of gene expression. Predicted to be active in cytoplasm. Orthologous to human IMPACT (impact RWD domain protein); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: imprinted and ancient; imprinted and ancient gene protein homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8184,383,546 - 4,422,280 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl184,383,575 - 4,422,278 (+)EnsemblGRCr8
mRatBN7.2184,108,872 - 4,147,571 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl184,108,853 - 4,147,569 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,343,551 - 4,371,274 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0185,131,117 - 5,158,842 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,390,783 - 4,418,239 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd184,787,992 - 4,815,442 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive184,388,759 - 4,416,215 (+)NCBILyon_Normotensive
Lyon_Hypertensive184,388,265 - 4,415,712 (+)NCBILyon_Hypertensive
F344_StmMcwi184,392,440 - 4,419,877 (+)NCBIF344_StmMcwi
Rnor_6.0184,325,872 - 4,346,734 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,325,875 - 4,346,769 (+)Ensemblrn6Rnor6.0
Rnor_5.0184,313,599 - 4,334,409 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera184,170,032 - 4,197,144 (+)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
Brodifacoum  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroethene  (ISO)
ciprofibrate  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
lead(0)  (ISO)
leflunomide  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15752730   PMID:15937339   PMID:22404850   PMID:23447528   PMID:24333428   PMID:30053369   PMID:32357304  


Genomics

Comparative Map Data
Impact
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8184,383,546 - 4,422,280 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl184,383,575 - 4,422,278 (+)EnsemblGRCr8
mRatBN7.2184,108,872 - 4,147,571 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl184,108,853 - 4,147,569 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,343,551 - 4,371,274 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0185,131,117 - 5,158,842 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,390,783 - 4,418,239 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd184,787,992 - 4,815,442 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive184,388,759 - 4,416,215 (+)NCBILyon_Normotensive
Lyon_Hypertensive184,388,265 - 4,415,712 (+)NCBILyon_Hypertensive
F344_StmMcwi184,392,440 - 4,419,877 (+)NCBIF344_StmMcwi
Rnor_6.0184,325,872 - 4,346,734 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,325,875 - 4,346,769 (+)Ensemblrn6Rnor6.0
Rnor_5.0184,313,599 - 4,334,409 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera184,170,032 - 4,197,144 (+)NCBICelera
Cytogenetic Map18p13NCBI
IMPACT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381824,426,670 - 24,453,531 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1824,426,634 - 24,453,531 (+)Ensemblhg38GRCh38
GRCh371822,006,634 - 22,033,495 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361820,260,680 - 20,287,490 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1818,821,663 - 18,848,543 (+)NCBICelera
Cytogenetic Map18q11.2NCBI
HuRef1818,862,705 - 18,889,562 (+)NCBIHuRef
CHM1_11821,933,622 - 21,960,504 (+)NCBICHM1_1
T2T-CHM13v2.01824,620,981 - 24,647,841 (+)NCBIT2T-CHM13v2.0
Impact
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391813,087,747 - 13,126,007 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1813,088,909 - 13,126,007 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381812,954,690 - 12,992,950 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1812,955,852 - 12,992,950 (+)Ensemblmm10GRCm38
MGSCv371813,130,761 - 13,151,457 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361813,115,421 - 13,136,117 (+)NCBIMGSCv36mm8
Celera1813,202,995 - 13,226,154 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map186.87NCBI
Impact
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540212,752,432 - 12,779,299 (+)Ensembl
ChiLan1.0NW_00495540212,752,748 - 12,781,238 (+)NCBIChiLan1.0ChiLan1.0
IMPACT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21741,857,324 - 41,899,242 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11827,549,919 - 27,591,837 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01817,678,297 - 17,720,348 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11821,299,078 - 21,340,902 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1821,299,213 - 21,322,868 (+)EnsemblpanPan2panpan1.1
IMPACT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1763,947,117 - 63,976,628 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl763,948,157 - 63,976,613 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha763,396,039 - 63,425,469 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0764,005,895 - 64,035,335 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl764,005,895 - 64,035,299 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1763,676,071 - 63,705,352 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0763,690,330 - 63,719,780 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0763,995,128 - 64,024,572 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Impact
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494460,021,857 - 60,050,176 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365503,766,061 - 3,795,112 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365503,765,952 - 3,795,183 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IMPACT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6109,235,585 - 109,272,793 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16109,235,590 - 109,272,801 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26102,002,343 - 102,039,536 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IMPACT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11856,081,440 - 56,123,067 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1856,092,481 - 56,122,963 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605030,801,609 - 30,868,014 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Impact
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247707,805,855 - 7,839,756 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247707,808,225 - 7,839,844 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Impact
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11530,709,818 - 30,738,520 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Impact
140 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:710
Count of miRNA genes:296
Interacting mature miRNAs:392
Transcripts:ENSRNOT00000073771
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
8552968Pigfal19Plasma insulin-like growth factor 1 level QTL 1911.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)18126032889Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18144930869Rat
1641910Colcr3Colorectal carcinoma resistance QTL 35.020.000007intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)18125022372Rat
1331781Scl28Serum cholesterol level QTL 283.995blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)18125071266Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18115642423Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18381190230809809Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134566578Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
9590248Scort10Serum corticosterone level QTL 1019.710.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)18126032889Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18154490981Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134566578Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)18430735449307354Rat

Markers in Region
RH131046  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8184,421,862 - 4,422,060 (+)Marker Load Pipeline
mRatBN7.2184,147,153 - 4,147,351 (+)MAPPERmRatBN7.2
Rnor_6.0184,346,317 - 4,346,514NCBIRnor6.0
Rnor_5.0184,333,992 - 4,334,189UniSTSRnor5.0
Celera184,196,727 - 4,196,924UniSTS
RH 3.4 Map1841.5UniSTS
RH143392  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2184,138,257 - 4,139,496 (+)MAPPERmRatBN7.2
Rnor_6.0184,337,356 - 4,338,593NCBIRnor6.0
Rnor_5.0184,325,083 - 4,326,320UniSTSRnor5.0
Celera184,187,823 - 4,189,060UniSTS
RH 3.4 Map1884.31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000073771   ⟹   ENSRNOP00000064200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl184,403,507 - 4,422,278 (+)Ensembl
mRatBN7.2 Ensembl184,128,794 - 4,147,569 (+)Ensembl
Rnor_6.0 Ensembl184,325,875 - 4,346,769 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116602   ⟹   ENSRNOP00000078372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl184,383,575 - 4,422,278 (+)Ensembl
mRatBN7.2 Ensembl184,108,853 - 4,147,567 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121832   ⟹   ENSRNOP00000102236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl184,401,479 - 4,422,278 (+)Ensembl
RefSeq Acc Id: NM_001012235   ⟹   NP_001012235
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8184,394,843 - 4,422,280 (+)NCBI
mRatBN7.2184,120,130 - 4,147,571 (+)NCBI
Dahl_SR_JrHsd184,787,992 - 4,815,442 (+)NCBI
Lyon_Normotensive184,388,759 - 4,416,215 (+)NCBI
Lyon_Hypertensive184,388,265 - 4,415,712 (+)NCBI
F344_StmMcwi184,392,440 - 4,419,877 (+)NCBI
Rnor_6.0184,325,872 - 4,346,734 (+)NCBI
Rnor_5.0184,313,599 - 4,334,409 (+)NCBI
Celera184,170,032 - 4,197,144 (+)RGD
Sequence:
RefSeq Acc Id: XM_039097018   ⟹   XP_038952946
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8184,383,560 - 4,422,280 (+)NCBI
mRatBN7.2184,108,872 - 4,147,571 (+)NCBI
RefSeq Acc Id: XM_063277509   ⟹   XP_063133579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8184,383,546 - 4,422,280 (+)NCBI
RefSeq Acc Id: XM_063277510   ⟹   XP_063133580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8184,383,546 - 4,422,280 (+)NCBI
RefSeq Acc Id: XM_063277511   ⟹   XP_063133581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8184,383,546 - 4,422,280 (+)NCBI
RefSeq Acc Id: XM_063277512   ⟹   XP_063133582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8184,383,560 - 4,422,280 (+)NCBI
RefSeq Acc Id: NP_001012235   ⟸   NM_001012235
- UniProtKB: Q5GFD9 (UniProtKB/Swiss-Prot),   A6KLS9 (UniProtKB/TrEMBL),   A0A8L2QV96 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064200   ⟸   ENSRNOT00000073771
RefSeq Acc Id: XP_038952946   ⟸   XM_039097018
- Peptide Label: isoform X1
- UniProtKB: Q5GFD9 (UniProtKB/Swiss-Prot),   A6KLS9 (UniProtKB/TrEMBL),   A0A8L2QV96 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078372   ⟸   ENSRNOT00000116602
RefSeq Acc Id: XP_063133579   ⟸   XM_063277509
- Peptide Label: isoform X1
- UniProtKB: Q5GFD9 (UniProtKB/Swiss-Prot),   A6KLS9 (UniProtKB/TrEMBL),   A0A8L2QV96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133581   ⟸   XM_063277511
- Peptide Label: isoform X1
- UniProtKB: Q5GFD9 (UniProtKB/Swiss-Prot),   A6KLS9 (UniProtKB/TrEMBL),   A0A8L2QV96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133580   ⟸   XM_063277510
- Peptide Label: isoform X1
- UniProtKB: Q5GFD9 (UniProtKB/Swiss-Prot),   A6KLS9 (UniProtKB/TrEMBL),   A0A8L2QV96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133582   ⟸   XM_063277512
- Peptide Label: isoform X1
- UniProtKB: Q5GFD9 (UniProtKB/Swiss-Prot),   A6KLS9 (UniProtKB/TrEMBL),   A0A8L2QV96 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102236   ⟸   ENSRNOT00000121832
Protein Domains
Impact N-terminal   RWD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5GFD9-F1-model_v2 AlphaFold Q5GFD9 1-317 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700643
Promoter ID:EPDNEW_R11166
Type:initiation region
Name:Impact_1
Description:impact RWD domain protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0184,325,854 - 4,325,914EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591977 AgrOrtholog
BioCyc Gene G2FUF-8339 BioCyc
Ensembl Genes ENSRNOG00000045844 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000116602 ENTREZGENE
  ENSRNOT00000116602.1 UniProtKB/Swiss-Prot
  ENSRNOT00000121832 ENTREZGENE
Gene3D-CATH 3.10.110.10 UniProtKB/Swiss-Prot
  3.30.230.30 UniProtKB/Swiss-Prot
InterPro Impact UniProtKB/Swiss-Prot
  Impact_N UniProtKB/Swiss-Prot
  Impact_N_sf UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot
  RWD-domain UniProtKB/Swiss-Prot
  UBQ-conjugating_enzyme/RWD UniProtKB/Swiss-Prot
  UPF0029_Impact_CS UniProtKB/Swiss-Prot
KEGG Report rno:497198 UniProtKB/Swiss-Prot
NCBI Gene 497198 ENTREZGENE
PANTHER PROTEIN IMPACT UniProtKB/Swiss-Prot
  PTHR16301 UniProtKB/Swiss-Prot
Pfam RWD UniProtKB/Swiss-Prot
  UPF0029 UniProtKB/Swiss-Prot
PhenoGen Impact PhenoGen
PROSITE RWD UniProtKB/Swiss-Prot
  UPF0029 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000045844 RatGTEx
SMART RWD UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54211 UniProtKB/Swiss-Prot
  SSF54495 UniProtKB/Swiss-Prot
UniProt A0A8L2QV96 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LKW4_RAT UniProtKB/TrEMBL
  A6KLS9 ENTREZGENE, UniProtKB/TrEMBL
  A6KLT0_RAT UniProtKB/TrEMBL
  A6KLT1_RAT UniProtKB/TrEMBL
  IMPCT_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5GFF2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-08-04 Impact  impact RWD domain protein  Impact  imprinted and ancient  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 Impact  imprinted and ancient      Symbol and Name status set to provisional 70820 PROVISIONAL