Aup1 (AUP1, lipid droplet regulating VLDL assembly factor) - Rat Genome Database

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Gene: Aup1 (AUP1, lipid droplet regulating VLDL assembly factor) Rattus norvegicus
Analyze
Symbol: Aup1
Name: AUP1, lipid droplet regulating VLDL assembly factor
RGD ID: 1591777
Description: Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including lipid droplet formation; lipophagy; and protein localization to lipid droplet. Predicted to be located in autophagosome; endoplasmic reticulum membrane; and lipid droplet. Predicted to be active in membrane. Orthologous to human AUP1 (AUP1 lipid droplet regulating VLDL assembly factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ancient ubiquitous protein 1; lipid droplet-regulating VLDL assembly factor AUP1; LOC680423; similar to Ancient ubiquitous protein 1 precursor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,118,035 - 117,121,063 (+)NCBIGRCr8
mRatBN7.24115,560,274 - 115,563,346 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4115,560,261 - 115,563,346 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,036,941 - 121,039,931 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04116,812,138 - 116,815,128 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,426,702 - 115,429,698 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04113,887,030 - 113,890,103 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4113,887,115 - 113,890,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04178,572,215 - 178,575,203 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,265,650 - 117,268,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4104,555,036 - 104,558,024 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
autophagosome  (IEA,ISO)
endoplasmic reticulum  (ISO)
endoplasmic reticulum membrane  (IBA,IEA,ISO,ISS)
lipid droplet  (IEA,ISO,ISS)
membrane  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:18299187   PMID:18570454   PMID:19946888   PMID:22871113   PMID:25660456  


Genomics

Comparative Map Data
Aup1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,118,035 - 117,121,063 (+)NCBIGRCr8
mRatBN7.24115,560,274 - 115,563,346 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4115,560,261 - 115,563,346 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,036,941 - 121,039,931 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04116,812,138 - 116,815,128 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,426,702 - 115,429,698 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04113,887,030 - 113,890,103 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4113,887,115 - 113,890,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04178,572,215 - 178,575,203 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,265,650 - 117,268,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4104,555,036 - 104,558,024 (+)NCBICelera
Cytogenetic Map4q34NCBI
AUP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38274,526,652 - 74,529,706 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl274,526,645 - 74,529,760 (-)EnsemblGRCh38hg38GRCh38
GRCh37274,753,779 - 74,756,833 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,607,283 - 74,610,482 (-)NCBINCBI36Build 36hg18NCBI36
Celera274,584,883 - 74,588,082 (-)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef274,490,036 - 74,493,235 (-)NCBIHuRef
CHM1_1274,683,171 - 74,686,370 (-)NCBICHM1_1
T2T-CHM13v2.0274,535,217 - 74,538,272 (-)NCBIT2T-CHM13v2.0
Aup1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,031,483 - 83,034,663 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,031,502 - 83,034,789 (+)EnsemblGRCm39 Ensembl
GRCm38683,054,495 - 83,057,682 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,054,521 - 83,057,808 (+)EnsemblGRCm38mm10GRCm38
MGSCv37683,004,647 - 83,007,676 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,020,386 - 83,023,340 (+)NCBIMGSCv36mm8
Celera685,037,242 - 85,040,271 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
Aup1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,259,432 - 11,262,269 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,259,288 - 11,262,413 (+)NCBIChiLan1.0ChiLan1.0
AUP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21251,859,528 - 51,862,602 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A51,862,282 - 51,865,356 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A74,593,260 - 74,596,372 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A76,099,483 - 76,102,774 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A76,099,634 - 76,102,464 (-)Ensemblpanpan1.1panPan2
AUP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11748,613,648 - 48,617,091 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1748,613,725 - 48,616,728 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,255,441 - 48,258,987 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01749,472,997 - 49,476,542 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1749,473,160 - 49,476,542 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11748,490,146 - 48,493,692 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01748,556,890 - 48,560,436 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,114,568 - 49,118,113 (+)NCBIUU_Cfam_GSD_1.0
Aup1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244062929,995,869 - 9,998,950 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936556739,094 - 742,034 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936556738,946 - 742,049 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AUP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl368,519,969 - 68,523,073 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1368,520,048 - 68,523,076 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2371,690,861 - 71,850,888 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AUP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,748,737 - 32,751,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1432,748,909 - 32,751,776 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604579,419,360 - 79,422,463 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aup1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474928,983,802 - 28,986,643 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474928,983,753 - 28,986,785 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aup1
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:64
Count of miRNA genes:61
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000010602
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)470808386115808386Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105789505150789505Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4106805662151805662Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat

Markers in Region
WI-19737  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24115,562,967 - 115,563,326 (+)MAPPERmRatBN7.2
Rnor_6.04113,889,725 - 113,890,083NCBIRnor6.0
Rnor_5.04178,574,825 - 178,575,183UniSTSRnor5.0
RGSC_v3.44117,268,260 - 117,268,618UniSTSRGSC3.4
Celera4104,557,646 - 104,558,004UniSTS
Cytogenetic Map4q34UniSTS
RH124966  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24115,561,661 - 115,561,745 (+)MAPPERmRatBN7.2
Rnor_6.04113,888,419 - 113,888,502NCBIRnor6.0
Rnor_5.04178,573,519 - 178,573,602UniSTSRnor5.0
RGSC_v3.44117,266,954 - 117,267,037UniSTSRGSC3.4
Celera4104,556,340 - 104,556,423UniSTS
Cytogenetic Map4q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010602   ⟹   ENSRNOP00000010602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4115,560,261 - 115,563,345 (+)Ensembl
Rnor_6.0 Ensembl4113,887,115 - 113,890,101 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104950   ⟹   ENSRNOP00000077286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4115,560,352 - 115,563,346 (+)Ensembl
RefSeq Acc Id: NM_001079899   ⟹   NP_001073368
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,118,075 - 117,121,063 (+)NCBI
mRatBN7.24115,560,360 - 115,563,346 (+)NCBI
Rnor_6.04113,887,115 - 113,890,103 (+)NCBI
Rnor_5.04178,572,215 - 178,575,203 (+)NCBI
RGSC_v3.44117,265,650 - 117,268,638 (+)RGD
Celera4104,555,036 - 104,558,024 (+)RGD
Sequence:
RefSeq Acc Id: XM_008763029   ⟹   XP_008761251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,118,035 - 117,120,772 (+)NCBI
mRatBN7.24115,560,275 - 115,563,000 (+)NCBI
Rnor_6.04113,887,030 - 113,889,706 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063286675   ⟹   XP_063142745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,118,035 - 117,121,063 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001073368   ⟸   NM_001079899
- UniProtKB: A1L134 (UniProtKB/Swiss-Prot),   A0A8L2Q4W6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761251   ⟸   XM_008763029
- Peptide Label: isoform X2
- UniProtKB: A0A8I5YCA8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010602   ⟸   ENSRNOT00000010602
RefSeq Acc Id: ENSRNOP00000077286   ⟸   ENSRNOT00000104950
RefSeq Acc Id: XP_063142745   ⟸   XM_063286675
- Peptide Label: isoform X1
Protein Domains
CUE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A1L134-F1-model_v2 AlphaFold A1L134 1-410 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693163
Promoter ID:EPDNEW_R3688
Type:multiple initiation site
Name:Aup1_1
Description:AUP1, lipid droplet regulating VLDL assembly factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04113,887,105 - 113,887,165EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591777 AgrOrtholog
BioCyc Gene G2FUF-44033 BioCyc
Ensembl Genes ENSRNOG00000007842 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010602 ENTREZGENE
  ENSRNOT00000010602.8 UniProtKB/TrEMBL
  ENSRNOT00000104950.1 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7319831 IMAGE-MGC_LOAD
InterPro AUP1_CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:680423 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156826 IMAGE-MGC_LOAD
NCBI Gene 680423 ENTREZGENE
PANTHER ANCIENT UBIQUITOUS PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIPID DROPLET-REGULATING VLDL ASSEMBLY FACTOR AUP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aup1 PhenoGen
PROSITE CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007842 RatGTEx
SMART CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glycerol-3-phosphate (1)-acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5YCA8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q4W6 ENTREZGENE, UniProtKB/TrEMBL
  A1L134 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-09 Aup1  AUP1, lipid droplet regulating VLDL assembly factor  Aup1  ancient ubiquitous protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Aup1  ancient ubiquitous protein 1  LOC680423  similar to Ancient ubiquitous protein 1 precursor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC680423  similar to Ancient ubiquitous protein 1 precursor      Symbol and Name status set to provisional 70820 PROVISIONAL