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Gene: Krt78 (keratin 78) Rattus norvegicus

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Symbol:

Krt78

Name:

keratin 78

RGD ID:

1591341

Description:

Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be located in intermediate filament. Predicted to be active in cornified envelope and keratin filament. Orthologous to human KRT78 (keratin 78); INTERACTS WITH bisphenol A; copper atom; copper(0).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Kb40; keratin 78, type II; keratin, type II cytoskeletal 78; LOC685672; similar to keratin Kb40; type II keratin Kb40

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KRT78 (keratin 78)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Krt78 (keratin 78)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Krt78 (keratin 78)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KRT78 (keratin 78)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KRT78 (keratin 78)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Krt78 (keratin 78)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KRT78 (keratin 78)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KRT78 (keratin 78)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Krt78 (keratin 78)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HCST (hematopoietic cell signal transducer)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	KRT78 (keratin 78)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	KRT78 (keratin 78)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Krt78 (keratin 78)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:172323	Alliance	DIOPT (Ensembl Compara\|OMA)
Danio rerio (zebrafish):	si:dkey-183i3.5	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Danio rerio (zebrafish):	zgc:136930	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	Muc11A	Alliance	DIOPT (OrthoInspector\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	134,952,877 - 134,960,727 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	134,953,043 - 134,960,220 (-)	Ensembl				GRCr8
mRatBN7.2	7	133,074,193 - 133,081,536 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	133,074,215 - 133,082,021 (-)	Ensembl				mRatBN7.2
Rnor_6.0	7	143,545,245 - 143,553,063 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	143,545,411 - 143,552,588 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	141,343,348 - 141,350,527 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	140,648,098 - 140,655,441 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	129,511,774 - 129,519,592 (-)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,6-dimethoxyphenol (ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

7,12-dimethyltetraphene (ISO)

aflatoxin B1 (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

copper atom (EXP)

copper(0) (EXP)

diazinon (ISO)

fonofos (ISO)

furfural (ISO)

genistein (ISO)

glyphosate (ISO)

hydroquinone (ISO)

indole-3-methanol (EXP)

methoxychlor (EXP)

okadaic acid (ISO)

ozone (ISO)

parathion (ISO)

PCB138 (ISO)

potassium dichromate (ISO)

rac-lactic acid (ISO)

sodium arsenate (ISO)

sodium chloride (ISO)

terbufos (ISO)

Tesaglitazar (EXP)

titanium dioxide (ISO)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intermediate filament organization (IBA)

keratinization (IBA)

Cellular Component

cornified envelope (IEA,ISO)

intermediate filament (IEA)

keratin filament (IBA,IEA)

Molecular Function

protein binding (ISO)

structural constituent of skin epidermis (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15085952	PMID:19199708	PMID:22664934	PMID:23376485

Genomics

Comparative Map Data

Krt78
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	134,952,877 - 134,960,727 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	134,953,043 - 134,960,220 (-)	Ensembl				GRCr8
mRatBN7.2	7	133,074,193 - 133,081,536 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	133,074,215 - 133,082,021 (-)	Ensembl				mRatBN7.2
Rnor_6.0	7	143,545,245 - 143,553,063 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	143,545,411 - 143,552,588 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	141,343,348 - 141,350,527 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	140,648,098 - 140,655,441 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	129,511,774 - 129,519,592 (-)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

KRT78
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	52,837,804 - 52,848,994 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	52,837,804 - 52,849,092 (-)	Ensembl			hg38	GRCh38
GRCh37	12	53,231,588 - 53,242,778 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	51,519,013 - 51,529,045 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	52,879,026 - 52,889,058 (-)	NCBI		Celera
Cytogenetic Map	12	q13.13	NCBI
HuRef	12	50,276,759 - 50,286,791 (-)	NCBI		HuRef
CHM1_1	12	53,199,552 - 53,209,584 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	52,802,261 - 52,813,482 (-)	NCBI		T2T-CHM13v2.0

Krt78
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	101,854,436 - 101,905,059 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	101,854,436 - 101,862,722 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm39 Ensembl	15	101,871,243 - 101,904,090 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	101,946,001 - 101,996,624 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	101,946,001 - 101,954,287 (-)	Ensembl			mm10	GRCm38
MGSCv37	15	101,776,435 - 101,784,718 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	102,925,015 - 102,932,267 (-)	NCBI		MGSCv36	mm8
MGSCv36	15	101,775,007 - 101,782,258 (-)	NCBI		MGSCv36	mm8
Celera	15	104,097,893 - 104,100,343 (-)	NCBI		Celera
Cytogenetic Map	15	F2	NCBI
cM Map	15	57.15	NCBI

Krt78
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	138,214 - 146,691 (-)	Ensembl
ChiLan1.0	NW_004955458	138,622 - 146,264 (-)	NCBI	ChiLan1.0	ChiLan1.0

KRT78
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	41,343,982 - 41,354,836 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	41,340,745 - 41,351,599 (+)	NCBI		NHGRI_mPanPan1

KRT78
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	2,257,161 - 2,264,945 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	43,987,339 - 43,995,081 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	2,258,358 - 2,266,129 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	2,259,357 - 2,266,960 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	2,274,858 - 2,282,612 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	2,261,054 - 2,268,796 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	44,386,311 - 44,394,037 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Krt78
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	62,953,941 - 62,962,048 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	10,203,807 - 10,210,472 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	10,202,810 - 10,210,480 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KRT78
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	18,124,156 - 18,133,061 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	18,124,201 - 18,132,994 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

KRT78
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	48,969,284 - 48,980,472 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	48,970,587 - 48,980,170 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	197,091,570 - 197,101,418 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Krt78
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624904	928,786 - 936,098 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Krt78
41 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	160
Count of miRNA genes:	91
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000047751, ENSRNOT00000074784
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	121393075	137014596	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	132099939	137014596	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	119280025	135560836	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	115313999	136544683	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

RH137424

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	133,074,276 - 133,074,460 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	143,545,329 - 143,545,512	NCBI	Rnor6.0
Rnor_5.0	7	141,343,432 - 141,343,615	UniSTS	Rnor5.0
RGSC_v3.4	7	140,648,182 - 140,648,365	UniSTS	RGSC3.4
Celera	7	129,511,858 - 129,512,041	UniSTS
RH 3.4 Map	7	1062.8	UniSTS
Cytogenetic Map	7	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	23	29	43	56	27	13	27	6	130	47	10	14	44	50	29	4	4

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001432506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC108351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BK004081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000086317 ⟹ ENSRNOP00000073048

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	134,953,043 - 134,960,220 (-)	Ensembl
mRatBN7.2 Ensembl	7	133,074,215 - 133,082,021 (-)	Ensembl
Rnor_6.0 Ensembl	7	143,545,411 - 143,552,588 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000092138 ⟹ ENSRNOP00000069199

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	143,547,250 - 143,552,588 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000092619 ⟹ ENSRNOP00000075749

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	143,545,724 - 143,552,588 (-)	Ensembl

RefSeq Acc Id:

XM_017595335 ⟹ XP_017450824

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	134,952,877 - 134,960,727 (-)	NCBI
mRatBN7.2	7	133,074,193 - 133,081,536 (-)	NCBI
Rnor_6.0	7	143,545,245 - 143,553,063 (-)	NCBI

Sequence:

show sequence

TGCATCACCTCTGCCAGCCTGGTTGCTCAGGGTCTGTGCTGCCTCTGTGAGGTTGGATCTCACT
TTGGGAGCTGCAGTCTTTCCTGACCTGCTGTCCCCAGCGCGCGCGCCCCTTCCCCGCTACCCTC
TCCTCGGCACAAACTCTTCTCACTCTTTCCTTGAACACCCTCAGTGATGTCGATACCTAGAACC
GTGGCTCAGGTCTCGAGACGCTTCCTTGTCTTTGGCTTCTAGGGCAGGGACTGGGTCTCCTACC
TCAAGCTTTGCACGTGCCACACACCTATTCTCCAGGTGTGTCAGAGCAGGTCAGCCGCAACAAG
CGGCAGACACAGTCAGACTGAGAACATCTTGCTATCCGAGGCCCAGCCCAAGGACGGGAGGGGA
TAAAAGTCTCGTGCCAGGGCCCCAGGGCAGAAGCACACACACCGTGACCATCTCCAGTCTGTCT
GAAGCTGCGGGCCTGCTTGTCTCTGCCATGTCTCTCTCTCCATGCCGGGCCCAGAGGGGCTTCA
GCGCTCGCTCAGCCTGCTCTGATTTTTCGGGGGCTCGAGGCAGGACCAGCTTCAGTAGCAGGAG
CCTTAGCTCCTCCAGGAGATGCAGAGGAAGCTCTTGTGGGAGGGCCTGGGGGGCAGAGACCAGG
CAAGGAGTACGGTTTGGACAGGGTAAGGGAGGGCCTGGGCTTTCTCAGTGCCCTCCAGGGGGCA
TCCAAGCAGTGACCATCGACCAGAGTCTGCTGACCCCACTGAAGATCGAGGTTGACCCCCAGTT
CCAGGTGGTGAAGACGCAGGAGACTCAAGAGATCAGAACCCTCAACAACCAGTTCGCCTCCTTC
ATTGACAAGGTACGCTTCCTGGAGCAGCAGAACAAGGTTCTGGAGACCAAGTGGGAGCTGCTGC
AGCAGCTGCAGGGGAATCGTAGCCCTCAGGGCCTGGAATGTGTCTTCGAAGCCTGCCTGGCCCG
GCTCAGGCAGCAGCTGGAAGAGCTGCAGAGAGAGCGGAGGGCTCTTGACTCTGAGCTGAAGACC
TACCAGGACCAGGAGGATGAATACAAGACCAAGTATGACCAGGAAGCATACAAGCACGCCTCGG
TGCAGAATGACTTTGTGGTCCTTAAGAAGGACGTGGATGAGGTTTTCCAGAGCAAGATGGATTT
GGAAGGCAACCTGGAGTCTCTGAGAGAGCACGTCTGTTTCTTGACACGTCTGTATGAGGAAGAA
CTGGGACAGCTGCAGACACAGGCAAACGATATGTCCGTGGTGCTGTCCATGGATAACAGCCGTT
GCTTAGACTTCAGTGACATCATCGCTGAGGTCCGCGCCCGTTATGAGGAGATCACGCGGACTAG
CAAGGCCGAGGCTGAGGCTGTGTTCCAGACCAAGTACCAGGAACTCCAGGAATCAGCCCAGCTT
CAAGGGAACAGCATGAAGGAAGTGCAGGTGCAGATCTCCCAGCTCCGGCAGGTCATACAGAAGC
TGCAGAGTCAGATTGGGAGCCTCAGGAAGCAGAATGACAGTCTGCAATCAGCCATTGCTGATGC
CGAGCAGCAAGGGGAGATGGCTCTGAGGGATGCTCAGGCCAAGCTGGATGAGCTGGAGGGTGCT
CTGAGAGCAGCCAAGCAGGACATGGCACAGATGCTCCGTGACTACCAGGAACTGATGGGCACAA
AGTTGTCCCTAGATGTGGAGATTGCCATGTACCGGAGACTGCTGGAGAGCGAGGAGTGCAGGAT
ATCCAAGGAGCACACCAGCCAGGTCACTGTCTCCATAGAAGAAGGCAGCATTGTACCTGGAAGA
AGTTGTGGAGGCCAAGTGGTCATCCCTGGAAGAAGTTGTGGAGGCCAAGTGGTCATCCCTGGAG
GAGTTTGTAGTGGCCAAGTAGTCATACCTGGAAGAAATTGTGGTGGCCAAGTGGTTATCCCTGG
AAGAACTTGTGGAGGCCAAGTGGTCATCCCTGGAAGAACTTGTGGAGGCCAAGTGACCATGCCT
GGAAGAGAATGTGGGGGCCAAGTGACAGTGCCTGGAAGAGAACATGGAGGCCAAGTGATCGTGC
CTGGAAGAGAACATGGCGGTCAAGTGACGGTGCCTGGAAGAGAACATGGCGGTCAAGTGACGGT
GCCTGGAAGAGAACATGGTGGTCAAGTGACGGTGCCTGGAAGAGAACATGGTGGTCAAGTGATG
GTGCCTGGAAGAGAACATGGAGGCCAAGTGACCATTCCTGGAAGAGAATGTGGGGGCCAAGTGA
CCATTCCTGGAAGAGAATATGGGGGCCAAGTGACGGTGCCTGGAAGAGAACATGGTGGTCAAGT
GACGGTGCCTGGAAGAGAATATGGGGGCCAAGTGACCGTGCCTGGAAGAGAACATGGAGGCCAA
GTGACCATTCCTGGAAGAGAATGTGGGGGTCAAGTGACCATTCCTGGAAGAGAATATGGGGGCC
AAGTGACGGTGCCTGGAAGAGAATATGGGGGCCAAGTGACCGTGTCTGGAAGAGAATATGGGGG
CCAAGTGACCGTGCCTGGAAGAGAATATGGGGGCCAAGTGACCGTGCCTGGAAGAGAATGTGGG
GGCCAAGTGACCGTGCCTGGAAGAGAATATGGGGGTCAAGTGACCGTGCCTGGAAGAGAATATG
GGGGTCAAGTGACCGTGCCTGGAAGAGAATGTGGGGGTCAAGTGACCGTGCCTGGAAGAGAATA
TGGGGGTCAAGTGACCGTGCCTGGAAGAGAATATGGGGGTCAAGTGACCGTGCCTGGAAGAGAA
TATGGGGGCCAAGTGACCGTGCCTGGAAGAGAATGTGGGGGTCAAGTGACCGTGCCTGGAAGAG
AATGTGGGGGTCAAGTGACGGTGCCTGGAAGAGAATATGGGGGTCAAGTGACGGTGCCTGGAAG
AGAATATGGGGGTCAAGTGACCATGCCTGGAAGAGAATGTGGGGGTCAAGTGATCGTGCCTGGA
AGAGAATGTGGGGGCCAAGTGACGATGCCTGGAAGAGAATGTGGGGGTCAAGTGACCGTGCCTG
GAAGAGAATATGGGGGCCAAGTGACCATGCCTGGAAGAGAATGTGGGGGCCAAGTGACCGTGTC
TGGAAGAGAATATGGGGGCCAAGTGATGCTGCCTGGAAGAGAGTGTGGGGGCCAAGTGACCGTG
CCTGGAAGAGAATGTGGGGGCCAAGTGACCATGCCTGGAAGAGAATGTGGGGGCCAAGTGACCA
TGCCTGGAAGAGAACATGGTGGTCAAGTGACCGTGCCTGGAAGAGAATGTGGGGGCCAAGTGAT
GCTGCCTGGAAGAGAGTGTGGGGGCCAAGTGGGCACTTGTGACCACAGAGGCTGGAAAGGTAGC
TTTGGGTCTGGAGGCTGCTCTAGCATTGTAACCGGTGGCTTTGATGTCCCCCAGGGGTCTGGGT
ACAGCCCCATCATGGGTTCCTGTTCTGTATCTGGCTCAGGCTTCAGCTCTGGCTCTGGCTCCAG
CTGCCGCACCATCCTGAAGAAGACAATGGAATCAAGCCGGAAGACGTCTGTCATTTATTGAGTG
ACCAGGCAGTCACATCCCTTCTGAGCCCAGTAGCCTTGCTCTGAGCCCATCCCCCATGTTTAGT
ACCCACAGCCCAAGGCAGCTCACTGGGCACTGGAGAAAGTCAATAAAGTCAGGCCTGCCTGCTG
TTCTGAGTGCTCAGGGGCAGGTCCTGTTCTGCACA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001419435	(Get FASTA)	NCBI Sequence Viewer
	XP_017450824	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	DAA04931	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000073048
	ENSRNOP00000073048.1

RefSeq Acc Id:

XP_017450824 ⟸ XM_017595335

- Sequence:

show sequence

MSLSPCRAQRGFSARSACSDFSGARGRTSFSSRSLSSSRRCRGSSCGRAWGAETRQGVRFGQGK
GGPGLSQCPPGGIQAVTIDQSLLTPLKIEVDPQFQVVKTQETQEIRTLNNQFASFIDKVRFLEQ
QNKVLETKWELLQQLQGNRSPQGLECVFEACLARLRQQLEELQRERRALDSELKTYQDQEDEYK
TKYDQEAYKHASVQNDFVVLKKDVDEVFQSKMDLEGNLESLREHVCFLTRLYEEELGQLQTQAN
DMSVVLSMDNSRCLDFSDIIAEVRARYEEITRTSKAEAEAVFQTKYQELQESAQLQGNSMKEVQ
VQISQLRQVIQKLQSQIGSLRKQNDSLQSAIADAEQQGEMALRDAQAKLDELEGALRAAKQDMA
QMLRDYQELMGTKLSLDVEIAMYRRLLESEECRISKEHTSQVTVSIEEGSIVPGRSCGGQVVIP
GRSCGGQVVIPGGVCSGQVVIPGRNCGGQVVIPGRTCGGQVVIPGRTCGGQVTMPGRECGGQVT
VPGREHGGQVIVPGREHGGQVTVPGREHGGQVTVPGREHGGQVTVPGREHGGQVMVPGREHGGQ
VTIPGRECGGQVTIPGREYGGQVTVPGREHGGQVTVPGREYGGQVTVPGREHGGQVTIPGRECG
GQVTIPGREYGGQVTVPGREYGGQVTVSGREYGGQVTVPGREYGGQVTVPGRECGGQVTVPGRE
YGGQVTVPGREYGGQVTVPGRECGGQVTVPGREYGGQVTVPGREYGGQVTVPGREYGGQVTVPG
RECGGQVTVPGRECGGQVTVPGREYGGQVTVPGREYGGQVTMPGRECGGQVIVPGRECGGQVTM
PGRECGGQVTVPGREYGGQVTMPGRECGGQVTVSGREYGGQVMLPGRECGGQVTVPGRECGGQV
TMPGRECGGQVTMPGREHGGQVTVPGRECGGQVMLPGRECGGQVGTCDHRGWKGSFGSGGCSSI
VTGGFDVPQGSGYSPIMGSCSVSGSGFSSGSGSSCRTILKKTMESSRKTSVIY

hide sequence

Ensembl Acc Id:

ENSRNOP00000069199 ⟸ ENSRNOT00000092138

Ensembl Acc Id:

ENSRNOP00000075749 ⟸ ENSRNOT00000092619

Ensembl Acc Id:

ENSRNOP00000073048 ⟸ ENSRNOT00000086317

Protein Domains

IF rod

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K4H7-F1-model_v2	AlphaFold	A0A0G2K4H7	1-1013	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695700

Promoter ID:

EPDNEW_R6209

Type:

single initiation site

Name:

Krt78_1

Description:

keratin 78

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	143,552,651 - 143,552,711	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1591341	AgrOrtholog
BioCyc Gene	G2FUF-31956	BioCyc
Ensembl Genes	ENSRNOG00000059790	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000086317	ENTREZGENE
	ENSRNOT00000086317.3	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.170	UniProtKB/TrEMBL
	Single helix bin	UniProtKB/TrEMBL
	Vasodilator-stimulated phosphoprotein	UniProtKB/TrEMBL
InterPro	IF_rod_dom	UniProtKB/TrEMBL
	Keratin_2_head	UniProtKB/TrEMBL
	Keratin_II	UniProtKB/TrEMBL
KEGG Report	rno:315324	UniProtKB/TrEMBL
NCBI Gene	Krt78	ENTREZGENE
PANTHER	GATA-TYPE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	KERATIN, TYPE II CYTOSKELETAL 78	UniProtKB/TrEMBL
Pfam	Filament	UniProtKB/TrEMBL
	Keratin_2_head	UniProtKB/TrEMBL
PhenoGen	Krt78	PhenoGen
PRINTS	TYPE2KERATIN	UniProtKB/TrEMBL
PROSITE	IF_ROD_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000059790	RatGTEx
SMART	Filament	UniProtKB/TrEMBL
Superfamily-SCOP	Intermediate filament protein, coiled coil region	UniProtKB/TrEMBL
UniProt	A0A0G2K4H7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-16	Krt78	keratin 78	Krt78	keratin 78, type II	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-01-28	Krt78	keratin 78, type II	Krt78	keratin 78	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-09-08	Krt78	keratin 78	Kb40	type II keratin Kb40	Data merged from RGD:1560272	737654	APPROVED
2008-03-05	Krt78	keratin 78	LOC685672	similar to keratin Kb40	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC685672	similar to keratin Kb40			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-02-09	Kb40	type II keratin Kb40			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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