Nme4 (NME/NM23 nucleoside diphosphate kinase 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Nme4 (NME/NM23 nucleoside diphosphate kinase 4) Rattus norvegicus
Analyze
Symbol: Nme4
Name: NME/NM23 nucleoside diphosphate kinase 4
RGD ID: 1591334
Description: Orthologous to human NME4 (NME/NM23 nucleoside diphosphate kinase 4); PARTICIPATES IN cardiolipin metabolic pathway; de novo pyrimidine biosynthetic pathway; purine metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: expressed in non-metastatic cells 4; expressed in non-metastatic cells 4, protein; LOC685679; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase 4; nucleoside diphosphate kinase, mitochondrial; similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,619,106 - 15,622,961 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1015,619,106 - 15,623,098 (-)EnsemblGRCr8
mRatBN7.21015,114,624 - 15,118,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,002,926 - 15,118,479 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1019,853,968 - 19,857,864 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,342,855 - 19,346,743 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,842,683 - 14,846,551 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,461,567 - 15,465,422 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,431,638 - 15,465,413 (-)Ensemblrn6Rnor6.0
Rnor_5.01015,275,267 - 15,279,122 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41015,360,310 - 15,364,165 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1014,783,047 - 14,786,902 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chloropicrin  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
indometacin  (EXP)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
mercury dichloride  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Localization and characterization of the mitochondrial isoform of the nucleoside diphosphate kinase in the pancreatic beta cell: evidence for its complexation with mitochondrial succinyl-CoA synthetase. Kowluru A, etal., Arch Biochem Biophys. 2002 Feb 15;398(2):160-9.
3. The human Nm23/nucleoside diphosphate kinases. Lacombe ML, etal., J Bioenerg Biomembr. 2000 Jun;32(3):247-58.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Metabolism and function of mitochondrial cardiolipin. Ren M, etal., Prog Lipid Res. 2014 Jul;55:1-16. doi: 10.1016/j.plipres.2014.04.001. Epub 2014 Apr 24.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch. Schlattner U, etal., J Biol Chem. 2013 Jan 4;288(1):111-21. doi: 10.1074/jbc.M112.408633. Epub 2012 Nov 13.
Additional References at PubMed
PMID:10799505   PMID:14651853   PMID:14766980   PMID:18614015   PMID:18635542  


Genomics

Comparative Map Data
Nme4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,619,106 - 15,622,961 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1015,619,106 - 15,623,098 (-)EnsemblGRCr8
mRatBN7.21015,114,624 - 15,118,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,002,926 - 15,118,479 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1019,853,968 - 19,857,864 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,342,855 - 19,346,743 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,842,683 - 14,846,551 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,461,567 - 15,465,422 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,431,638 - 15,465,413 (-)Ensemblrn6Rnor6.0
Rnor_5.01015,275,267 - 15,279,122 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41015,360,310 - 15,364,165 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1014,783,047 - 14,786,902 (-)NCBICelera
Cytogenetic Map10q12NCBI
NME4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816396,729 - 400,754 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16396,725 - 410,367 (+)Ensemblhg38GRCh38
GRCh3716446,729 - 450,754 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616387,193 - 390,755 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3416387,192 - 390,754NCBI
Celera16647,739 - 651,301 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16368,052 - 369,816 (+)NCBIHuRef
CHM1_116447,138 - 450,694 (+)NCBICHM1_1
T2T-CHM13v2.016392,618 - 396,999 (+)NCBIT2T-CHM13v2.0
Nme4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,310,708 - 26,314,650 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,310,708 - 26,314,576 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381726,091,734 - 26,095,523 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,091,734 - 26,095,602 (-)Ensemblmm10GRCm38
MGSCv371726,228,690 - 26,232,415 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361725,819,345 - 25,823,070 (-)NCBIMGSCv36mm8
Celera1726,625,701 - 26,629,418 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.06NCBI
Nme4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,808,215 - 16,811,302 (-)Ensembl
ChiLan1.0NW_00495544216,808,215 - 16,811,302 (-)NCBIChiLan1.0ChiLan1.0
NME4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218626,531 - 630,084 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,416,006 - 4,419,451 (+)NCBINHGRI_mPanPan1
PanPan1.116374,718 - 393,976 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16389,068 - 393,976 (+)EnsemblpanPan2panpan1.1
NME4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,119,443 - 40,122,418 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,382,427 - 41,385,445 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0640,461,109 - 40,464,127 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1640,149,487 - 40,152,505 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0640,109,690 - 40,112,657 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,588,923 - 40,591,941 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nme4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,455,086 - 112,459,909 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501553,936 - 557,741 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936501553,931 - 557,744 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NME4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,306,175 - 41,310,312 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1341,306,167 - 41,321,002 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,117,780 - 41,121,920 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NME4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15337,533 - 341,052 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5337,562 - 341,205 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606830,831,389 - 30,835,230 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nme4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,234,191 - 1,237,602 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249131,234,292 - 1,237,602 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nme4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v193,352,421 - 3,356,023 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nme4
18 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:149
Interacting mature miRNAs:155
Transcripts:ENSRNOT00000027593
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
RH128482  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21015,114,722 - 15,114,938 (+)MAPPERmRatBN7.2
Rnor_6.01015,461,666 - 15,461,881NCBIRnor6.0
Rnor_5.01015,275,366 - 15,275,581UniSTSRnor5.0
RGSC_v3.41015,360,409 - 15,360,624UniSTSRGSC3.4
Celera1014,783,146 - 14,783,361UniSTS
RH 3.4 Map10155.0UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 1 24 80 34 30 18 56 18 6 179 102 11 66 46 51 12 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027593   ⟹   ENSRNOP00000027593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1015,619,106 - 15,623,098 (-)Ensembl
RefSeq Acc Id: NM_001109478   ⟹   NP_001102948
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,619,106 - 15,622,961 (-)NCBI
mRatBN7.21015,114,624 - 15,118,479 (-)NCBI
Rnor_6.01015,461,567 - 15,465,422 (-)NCBI
Rnor_5.01015,275,267 - 15,279,122 (-)NCBI
RGSC_v3.41015,360,310 - 15,364,165 (-)RGD
Celera1014,783,047 - 14,786,902 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102948 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03992 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027593
  ENSRNOP00000027593.5
  ENSRNOP00000110670.1
RefSeq Acc Id: NP_001102948   ⟸   NM_001109478
- UniProtKB: D3ZMT9 (UniProtKB/TrEMBL),   A6HD87 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027593   ⟸   ENSRNOT00000027593
Protein Domains
Nucleoside diphosphate kinase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H66-F1-model_v2 AlphaFold Q66H66 1-446 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697070
Promoter ID:EPDNEW_R7594
Type:multiple initiation site
Name:Nme4_1
Description:NME/NM23 nucleoside diphosphate kinase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7593  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01015,465,425 - 15,465,485EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591334 AgrOrtholog
BioCyc Gene G2FUF-25731 BioCyc
BioCyc Pathway PWY-7176 [UTP and CTP de novo biosynthesis] BioCyc
  PWY-7184 [pyrimidine deoxyribonucleotides de novo biosynthesis I] BioCyc
  PWY-7197 [pyrimidine deoxyribonucleotide phosphorylation] BioCyc
  PWY-7205 [CMP phosphorylation] BioCyc
  PWY-7210 [pyrimidine deoxyribonucleotides biosynthesis from CTP] BioCyc
  PWY-7221 [guanosine ribonucleotides de novo biosynthesis] BioCyc
  PWY-7224 [purine deoxyribonucleosides salvage] BioCyc
  PWY-7226 [guanosine deoxyribonucleotides de novo biosynthesis I] BioCyc
  PWY-7227 [adenosine deoxyribonucleotides de novo biosynthesis I] BioCyc
BioCyc Pathway Image PWY-7176 BioCyc
  PWY-7184 BioCyc
  PWY-7197 BioCyc
  PWY-7205 BioCyc
  PWY-7210 BioCyc
  PWY-7221 BioCyc
  PWY-7224 BioCyc
  PWY-7226 BioCyc
  PWY-7227 BioCyc
Ensembl Genes ENSRNOG00000032152 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000050424 Ensembl
  ENSRNOG00000075475 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027593 ENTREZGENE
  ENSRNOT00000027593.8 UniProtKB/TrEMBL
  ENSRNOT00000165479.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.141 UniProtKB/TrEMBL
InterPro NDK-like_dom UniProtKB/TrEMBL
  NDK-like_dom_sf UniProtKB/TrEMBL
  Nucleoside_diP_kinase UniProtKB/TrEMBL
  Nucleoside_diP_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:685679 UniProtKB/TrEMBL
NCBI Gene 685679 ENTREZGENE
PANTHER NUCLEOSIDE DIPHOSPHATE KINASE UniProtKB/TrEMBL
Pfam NDK UniProtKB/TrEMBL
PhenoGen Nme4 PhenoGen
PRINTS NUCDPKINASE UniProtKB/TrEMBL
PROSITE NDP_KINASES UniProtKB/TrEMBL
  NDPK_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032152 RatGTEx
  ENSRNOG00000050424 RatGTEx
  ENSRNOG00000075475 RatGTEx
SMART NDK UniProtKB/TrEMBL
Superfamily-SCOP SSF54919 UniProtKB/TrEMBL
UniProt A0ABK0M555_RAT UniProtKB/TrEMBL
  A6HD87 ENTREZGENE, UniProtKB/TrEMBL
  D3ZMT9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-05 Nme4  NME/NM23 nucleoside diphosphate kinase 4  Nme4  non-metastatic cells 4, protein expressed in  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-07-08 Nme4  non-metastatic cells 4, protein expressed in  LOC682382  similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)  Data merged from RGD:1584567 1643240 APPROVED
2008-05-15 Nme4  non-metastatic cells 4, protein expressed in  Nme4  expressed in non-metastatic cells 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Nme4  expressed in non-metastatic cells 4  LOC685679  similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC685679  similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC682382  similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)      Symbol and Name status set to provisional 70820 PROVISIONAL