Or7e178 (olfactory receptor, family 7, subfamily E, member 178) - Rat Genome Database

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Gene: Or7e178 (olfactory receptor, family 7, subfamily E, member 178) Rattus norvegicus
Analyze
Symbol: Or7e178 (Ensembl: Or7e24)
Name: olfactory receptor, family 7, subfamily E, member 178 (Ensembl:olfactory receptor, family 7, subfamily E, member 24)
RGD ID: 1590984
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR7E24 (olfactory receptor family 7 subfamily E member 24); INTERACTS WITH 1,2-dichloroethane (ortholog); Azoxymethane (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: olfactory receptor, family 7, subfamily E, member 24; Or7e24; putative gustatory receptor clone PTE01; similar to olfactory receptor 873
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8826,999,759 - 27,012,158 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl826,999,759 - 27,012,158 (-)EnsemblGRCr8
mRatBN7.2818,723,515 - 18,735,910 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl818,725,214 - 18,735,776 (-)EnsemblmRatBN7.2
Rnor_6.0821,214,143 - 21,224,737 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,214,143 - 21,224,737 (-)Ensemblrn6Rnor6.0
Rnor_5.0821,277,832 - 21,312,219 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4819,198,705 - 19,209,347 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera820,132,990 - 20,143,552 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8380780  


Genomics

Comparative Map Data
Or7e178
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8826,999,759 - 27,012,158 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl826,999,759 - 27,012,158 (-)EnsemblGRCr8
mRatBN7.2818,723,515 - 18,735,910 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl818,725,214 - 18,735,776 (-)EnsemblmRatBN7.2
Rnor_6.0821,214,143 - 21,224,737 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,214,143 - 21,224,737 (-)Ensemblrn6Rnor6.0
Rnor_5.0821,277,832 - 21,312,219 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4819,198,705 - 19,209,347 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera820,132,990 - 20,143,552 (-)NCBICelera
Cytogenetic Map8q13NCBI
Or7e178
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,223,391 - 20,247,389 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,223,448 - 20,247,390 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38920,313,892 - 20,336,094 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,312,152 - 20,336,094 (-)Ensemblmm10GRCm38
MGSCv37920,118,336 - 20,140,538 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36920,064,325 - 20,065,663 (-)NCBIMGSCv36mm8
Celera917,594,808 - 17,612,439 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.52NCBI

Variants

.
Variants in Or7e178
44 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:139
Count of miRNA genes:120
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000067321, ENSRNOT00000072834, ENSRNOT00000074280
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8132882639Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
1 5 2 4 1 2 1 6 2 6 2 4 3

Sequence


Ensembl Acc Id: ENSRNOT00000067321   ⟹   ENSRNOP00000061016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl818,725,214 - 18,735,776 (-)Ensembl
Rnor_6.0 Ensembl821,214,143 - 21,224,737 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000169026   ⟹   ENSRNOP00000100057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl826,999,759 - 27,012,158 (-)Ensembl
RefSeq Acc Id: NM_001419709   ⟹   NP_001406638
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8826,999,759 - 27,012,158 (-)NCBI
mRatBN7.2818,723,515 - 18,735,910 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001406638 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000100057
GenBank Protein P35894 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000061016   ⟸   ENSRNOT00000067321
RefSeq Acc Id: NP_001406638   ⟸   NM_001419709
- UniProtKB: F1M946 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100057   ⟸   ENSRNOT00000169026

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35894-F1-model_v2 AlphaFold P35894 1-185 view protein structure
AF-F1M946-F1-model_v2 AlphaFold F1M946 1-331 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1590984 AgrOrtholog
BioCyc Gene G2FUF-31485 BioCyc
Ensembl Genes ENSRNOG00000056873 Ensembl
  ENSRNOG00000090131 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000169026 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Olfact_rcpt UniProtKB/Swiss-Prot
NCBI Gene 690849 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/Swiss-Prot
Pfam 7tm_4 UniProtKB/Swiss-Prot
PhenoGen Or7e178 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  OLFACTORYR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000056873 RatGTEx
  ENSRNOG00000090131 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A0ABK0KYF5_RAT UniProtKB/TrEMBL
  F1M946 ENTREZGENE, UniProtKB/TrEMBL
  GU01_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-01-10 Or7e178  olfactory receptor, family 7, subfamily E, member 178  Or7e24  olfactory receptor, family 7, subfamily E, member 24  Name and Symbol changed 629549 APPROVED
2008-01-09 LOC690849  similar to olfactory receptor 873  LOC687019  similar to olfactory receptor 873  Data merged from RGD:1590149 1643240 APPROVED
2006-11-20 LOC690849  similar to olfactory receptor 873      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC687019  similar to olfactory receptor 873      Symbol and Name status set to provisional 70820 PROVISIONAL