Tcf24 (transcription factor 24) - Rat Genome Database

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Gene: Tcf24 (transcription factor 24) Rattus norvegicus
Analyze
Symbol: Tcf24
Name: transcription factor 24
RGD ID: 1589398
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Orthologous to human TCF24 (transcription factor 24); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: similar to transcription factor 23
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8514,057,482 - 14,064,615 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl514,058,039 - 14,063,345 (+)EnsemblGRCr8
mRatBN7.259,274,659 - 9,282,876 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl59,227,131 - 9,279,636 (+)EnsemblmRatBN7.2
Rnor_6.058,957,107 - 8,961,523 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl58,957,405 - 8,961,337 (+)Ensemblrn6Rnor6.0
Rnor_5.0513,764,396 - 13,768,668 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.458,819,880 - 8,840,882 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Cytogenetic Map5q11NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Tcf24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8514,057,482 - 14,064,615 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl514,058,039 - 14,063,345 (+)EnsemblGRCr8
mRatBN7.259,274,659 - 9,282,876 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl59,227,131 - 9,279,636 (+)EnsemblmRatBN7.2
Rnor_6.058,957,107 - 8,961,523 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl58,957,405 - 8,961,337 (+)Ensemblrn6Rnor6.0
Rnor_5.0513,764,396 - 13,768,668 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.458,819,880 - 8,840,882 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Cytogenetic Map5q11NCBI
TCF24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38866,946,501 - 66,962,591 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl866,946,491 - 66,962,591 (-)Ensemblhg38GRCh38
GRCh37867,858,736 - 67,874,826 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36868,022,627 - 68,040,962 (-)NCBIBuild 36Build 36hg18NCBI36
Celera863,852,112 - 63,868,245 (-)NCBICelera
Cytogenetic Map8q13.1NCBI
HuRef863,351,441 - 63,367,585 (-)NCBIHuRef
CHM1_1867,913,776 - 67,929,869 (-)NCBICHM1_1
T2T-CHM13v2.0867,372,982 - 67,389,072 (-)NCBIT2T-CHM13v2.0
Tcf24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39110,030,388 - 10,038,207 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl110,030,388 - 10,038,157 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3819,960,163 - 9,967,981 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl19,960,163 - 9,967,932 (-)Ensemblmm10GRCm38
MGSCv3719,953,489 - 9,957,566 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3619,953,489 - 9,957,566 (-)NCBIMGSCv36mm8
Celera19,934,183 - 9,941,501 (-)NCBICelera
Cytogenetic Map1A2NCBI
cM Map12.24NCBI
Tcf24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544412,305,496 - 12,318,230 (+)NCBIChiLan1.0ChiLan1.0
TCF24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2782,681,840 - 82,699,290 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1858,324,124 - 58,341,551 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0863,489,514 - 63,504,961 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1865,152,169 - 65,168,734 (-)NCBIPanPan1.1PanPan1.1panPan2
TCF24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12916,478,892 - 16,490,443 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2916,482,749 - 16,491,273 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2916,794,499 - 16,806,035 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02916,559,395 - 16,570,888 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2916,563,259 - 16,571,793 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12916,591,360 - 16,602,898 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02916,691,208 - 16,702,726 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02916,947,563 - 16,959,108 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tcf24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530367,662,711 - 67,672,394 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364967,114,185 - 7,122,790 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364967,114,938 - 7,122,742 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCF24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl467,816,938 - 67,825,294 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1467,816,464 - 67,824,470 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2473,876,511 - 73,884,933 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TCF24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1862,815,782 - 62,824,301 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl862,817,349 - 62,823,730 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603978,681,784 - 78,689,756 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tcf24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474424,388,788 - 24,401,351 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474424,387,459 - 24,405,437 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tcf24
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11144,722,388 - 144,726,075 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tcf24
87 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5692228237468560Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
631827Alc4Alcohol consumption QTL 43.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)51297048025683802Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 1 39 75 75 77 55 29 55 4 232 88 10 55 78 90 22 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000088164   ⟹   ENSRNOP00000069940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl59,227,131 - 9,279,636 (+)Ensembl
Rnor_6.0 Ensembl58,957,405 - 8,961,337 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000130044   ⟹   ENSRNOP00000101240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl514,058,039 - 14,063,345 (+)Ensembl
RefSeq Acc Id: XM_008763519   ⟹   XP_008761741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,057,482 - 14,064,615 (+)NCBI
mRatBN7.259,274,659 - 9,282,876 (+)NCBI
Rnor_6.058,957,107 - 8,961,433 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110920   ⟹   XP_038966848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,057,482 - 14,064,615 (+)NCBI
mRatBN7.259,274,659 - 9,282,876 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008761741 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966848 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000101240
  ENSRNOP00000101240.1
RefSeq Acc Id: XP_008761741   ⟸   XM_008763519
- UniProtKB: A0A0G2JWM6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069940   ⟸   ENSRNOT00000088164
RefSeq Acc Id: XP_038966848   ⟸   XM_039110920
- UniProtKB: A0A0G2JWM6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101240   ⟸   ENSRNOT00000130044

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JWM6-F1-model_v2 AlphaFold A0A0G2JWM6 1-170 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589398 AgrOrtholog
BioCyc Gene G2FUF-42207 BioCyc
Ensembl Genes ENSRNOG00000052668 Ensembl
  ENSRNOG00000087348 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000130044 ENTREZGENE
  ENSRNOT00000130044.1 UniProtKB/TrEMBL
NCBI Gene 680678 ENTREZGENE
PhenoGen Tcf24 PhenoGen
RatGTEx ENSRNOG00000052668 RatGTEx
  ENSRNOG00000087348 RatGTEx
UniProt A0A0G2JWM6 ENTREZGENE
  A0ABK0L9H2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-11-19 LOC680678  similar to transcription factor 23      Symbol and Name status set to provisional 70820 PROVISIONAL