Gstz1 (glutathione S-transferase zeta 1) - Rat Genome Database

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Gene: Gstz1 (glutathione S-transferase zeta 1) Rattus norvegicus
Analyze
Symbol: Gstz1
Name: glutathione S-transferase zeta 1
RGD ID: 1589363
Description: Predicted to enable glutathione transferase activity; maleylacetoacetate isomerase activity; and protein homodimerization activity. Involved in cellular detoxification. Is active in cytosol and mitochondrial matrix. Orthologous to human GSTZ1 (glutathione S-transferase zeta 1); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glutathione S-transferase alpha 3; glutathione transferase zeta 1; GSTZ1-1; LOC681913; MAAI; maleylacetoacetate isomerase; similar to Maleylacetoacetate isomerase (MAAI) (Glutathione S-transferase zeta 1) (GSTZ1-1)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86112,525,576 - 112,536,228 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6112,525,377 - 112,536,233 (+)EnsemblGRCr8
mRatBN7.26106,794,594 - 106,805,284 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6106,794,074 - 106,805,284 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6106,962,390 - 106,973,018 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06107,261,228 - 107,271,856 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06106,630,899 - 106,641,529 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06111,176,798 - 111,187,246 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,176,798 - 111,187,244 (+)Ensemblrn6Rnor6.0
Rnor_5.06120,460,963 - 120,471,411 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera6104,615,943 - 104,626,563 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
(S)-naringenin  (ISO)
1,1-dichloroethene  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrabromodibenzodioxine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
8'-apo-beta,psi-caroten-8'-al  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
amiodarone  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-carotene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfide  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cerium trichloride  (ISO)
chlorpyrifos  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
cobalt dichloride  (ISO)
crocidolite asbestos  (ISO)
cumene hydroperoxide  (ISO)
cyclosporin A  (ISO)
cyfluthrin  (ISO)
decabromodiphenyl ether  (EXP,ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (EXP,ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
enzyme inhibitor  (ISO)
etacrynic acid  (ISO)
flutamide  (EXP)
fumonisin B1  (ISO)
glafenine  (EXP)
glutathione  (ISO)
hemin  (ISO)
hydrogen peroxide  (ISO)
iodide salt  (ISO)
isoflavones  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lanthanum trichloride  (ISO)
lead diacetate  (EXP)
methylmercury chloride  (ISO)
microcystin  (EXP)
microcystin-LR  (EXP)
N-nitrosomorpholine  (EXP)
nimesulide  (EXP)
nitrofen  (EXP)
ochratoxin A  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
sarin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
stilbene oxide  (ISO)
sulfites  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
XL147  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IDA,ISO)
mitochondrial matrix  (IDA)
mitochondrion  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1. Li W, etal., J Pharmacol Exp Ther. 2011 Jan;336(1):87-94. doi: 10.1124/jpet.110.173195. Epub 2010 Sep 30.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9531472   PMID:10739172   PMID:11327815   PMID:12477932   PMID:14651853   PMID:16189514   PMID:25416956   PMID:29626439  


Genomics

Comparative Map Data
Gstz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86112,525,576 - 112,536,228 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6112,525,377 - 112,536,233 (+)EnsemblGRCr8
mRatBN7.26106,794,594 - 106,805,284 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6106,794,074 - 106,805,284 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6106,962,390 - 106,973,018 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06107,261,228 - 107,271,856 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06106,630,899 - 106,641,529 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06111,176,798 - 111,187,246 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,176,798 - 111,187,244 (+)Ensemblrn6Rnor6.0
Rnor_5.06120,460,963 - 120,471,411 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera6104,615,943 - 104,626,563 (+)NCBICelera
Cytogenetic Map6q31NCBI
GSTZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381477,321,036 - 77,331,597 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1477,320,996 - 77,331,597 (+)Ensemblhg38GRCh38
GRCh371477,787,379 - 77,797,940 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361476,857,107 - 76,867,693 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341476,857,106 - 76,867,692NCBI
Celera1457,825,806 - 57,836,516 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1457,953,339 - 57,964,018 (+)NCBIHuRef
CHM1_11477,726,689 - 77,737,398 (+)NCBICHM1_1
T2T-CHM13v2.01471,530,399 - 71,540,959 (+)NCBIT2T-CHM13v2.0
Gstz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391287,192,102 - 87,211,497 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1287,193,939 - 87,211,497 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381287,147,161 - 87,164,723 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1287,147,165 - 87,164,723 (+)Ensemblmm10GRCm38
MGSCv371288,488,668 - 88,505,673 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361288,036,821 - 88,053,826 (+)NCBIMGSCv36mm8
Celera1288,612,223 - 88,629,231 (+)NCBICelera
Cytogenetic Map12D2NCBI
cM Map1241.34NCBI
Gstz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554381,219,018 - 1,231,287 (+)Ensembl
ChiLan1.0NW_0049554381,218,990 - 1,231,407 (+)NCBIChiLan1.0ChiLan1.0
GSTZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21578,404,884 - 78,432,045 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11477,621,388 - 77,648,486 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01457,874,184 - 57,901,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11477,075,814 - 77,102,745 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1477,075,814 - 77,086,530 (+)EnsemblpanPan2panpan1.1
GSTZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1850,133,496 - 50,143,487 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl850,133,714 - 50,143,439 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha849,821,231 - 49,831,169 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0850,367,085 - 50,377,034 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl850,367,124 - 50,377,028 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1850,029,935 - 50,039,870 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0850,052,790 - 50,063,232 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0850,450,973 - 50,460,913 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gstz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864025,910,957 - 25,927,021 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364886,141,317 - 6,154,075 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364886,141,913 - 6,153,591 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSTZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7100,392,271 - 100,408,420 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17100,392,217 - 100,404,025 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27106,553,162 - 106,564,936 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GSTZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12454,567,594 - 54,578,262 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2454,567,655 - 54,579,613 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605342,767,574 - 42,778,242 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gstz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473424,575,540 - 24,595,784 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473424,575,009 - 24,595,944 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Gstz1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17101,248,687 - 101,259,259 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gstz1
34 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:181
Count of miRNA genes:145
Interacting mature miRNAs:162
Transcripts:ENSRNOT00000072215
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)699437079125323237Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat

Markers in Region
RH137359  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26106,805,004 - 106,805,201 (+)MAPPERmRatBN7.2
Rnor_6.06111,186,972 - 111,187,168NCBIRnor6.0
Rnor_5.06120,471,137 - 120,471,333UniSTSRnor5.0
Celera6104,626,291 - 104,626,487UniSTS
RH 3.4 Map6748.89UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000072215   ⟹   ENSRNOP00000065390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6112,525,377 - 112,536,233 (+)Ensembl
mRatBN7.2 Ensembl6106,794,074 - 106,805,284 (+)Ensembl
Rnor_6.0 Ensembl6111,176,798 - 111,187,244 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082027   ⟹   ENSRNOP00000073813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6112,529,077 - 112,536,233 (+)Ensembl
mRatBN7.2 Ensembl6106,798,160 - 106,804,566 (+)Ensembl
Rnor_6.0 Ensembl6111,180,108 - 111,186,546 (+)Ensembl
RefSeq Acc Id: NM_001109445   ⟹   NP_001102915
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86112,525,606 - 112,536,226 (+)NCBI
mRatBN7.26106,794,656 - 106,805,277 (+)NCBI
Rnor_6.06111,176,798 - 111,187,244 (+)NCBI
Rnor_5.06120,460,963 - 120,471,411 (+)NCBI
Celera6104,615,943 - 104,626,563 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240399   ⟹   XP_006240461
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86112,528,968 - 112,536,228 (+)NCBI
mRatBN7.26106,798,069 - 106,805,284 (+)NCBI
Rnor_6.06111,180,209 - 111,187,246 (+)NCBI
Rnor_5.06120,460,963 - 120,471,411 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039112925   ⟹   XP_038968853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86112,525,576 - 112,533,586 (+)NCBI
mRatBN7.26106,794,594 - 106,802,606 (+)NCBI
RefSeq Acc Id: XM_063262472   ⟹   XP_063118542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86112,529,140 - 112,536,228 (+)NCBI
RefSeq Acc Id: NP_001102915   ⟸   NM_001109445
- UniProtKB: B0BNI1 (UniProtKB/Swiss-Prot),   P57113 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240461   ⟸   XM_006240399
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K6H2 (UniProtKB/TrEMBL),   A6JE83 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073813   ⟸   ENSRNOT00000082027
Ensembl Acc Id: ENSRNOP00000065390   ⟸   ENSRNOT00000072215
RefSeq Acc Id: XP_038968853   ⟸   XM_039112925
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118542   ⟸   XM_063262472
- Peptide Label: isoform X3
- UniProtKB: A6JE85 (UniProtKB/TrEMBL)
Protein Domains
GST C-terminal   GST N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P57113-F1-model_v2 AlphaFold P57113 1-216 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694751
Promoter ID:EPDNEW_R5276
Type:multiple initiation site
Name:Gstz1_2
Description:glutathione S-transferase zeta 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5278  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06111,176,846 - 111,176,906EPDNEW
RGD ID:13694753
Promoter ID:EPDNEW_R5278
Type:initiation region
Name:Gstz1_1
Description:glutathione S-transferase zeta 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5276  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06111,180,288 - 111,180,348EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589363 AgrOrtholog
BioCyc Gene G2FUF-36726 BioCyc
BioCyc Pathway TYRFUMCAT-PWY [L-tyrosine degradation I] BioCyc
BioCyc Pathway Image TYRFUMCAT-PWY BioCyc
Ensembl Genes ENSRNOG00000047708 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000072215 ENTREZGENE
  ENSRNOT00000082027 ENTREZGENE
Gene3D-CATH 1.20.1050.10 UniProtKB/Swiss-Prot
  Glutaredoxin UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7381517 IMAGE-MGC_LOAD
InterPro Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot
  Glutathione_S-Trfase UniProtKB/Swiss-Prot
  Glutathione_S-Trfase_N UniProtKB/Swiss-Prot
  GST_C UniProtKB/Swiss-Prot
  GST_Zeta UniProtKB/Swiss-Prot
  GST_Zeta_C UniProtKB/Swiss-Prot
  GST_Zeta_N UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:681913 UniProtKB/Swiss-Prot
MGC_CLONE MGC:188285 IMAGE-MGC_LOAD
NCBI Gene 681913 ENTREZGENE
PANTHER MALEYLACETOACETATE ISOMERASE UniProtKB/Swiss-Prot
  MALEYLACETOACETATE ISOMERASE UniProtKB/Swiss-Prot
Pfam GST_C_3 UniProtKB/Swiss-Prot
  GST_N_2 UniProtKB/Swiss-Prot
PhenoGen Gstz1 PhenoGen
PROSITE GST_CTER UniProtKB/Swiss-Prot
  GST_NTER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000047708 RatGTEx
Superfamily-SCOP SSF47616 UniProtKB/Swiss-Prot
  SSF52833 UniProtKB/Swiss-Prot
UniProt A0A0G2K6H2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QW65_RAT UniProtKB/TrEMBL
  A6JE83 ENTREZGENE, UniProtKB/TrEMBL
  A6JE85 ENTREZGENE, UniProtKB/TrEMBL
  B0BNI1 ENTREZGENE
  MAAI_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B0BNI1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-16 Gstz1  glutathione S-transferase zeta 1  Gstz1  glutathione transferase zeta 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-02 Gstz1  glutathione transferase zeta 1  LOC681913  similar to Maleylacetoacetate isomerase (MAAI) (Glutathione S-transferase zeta 1) (GSTZ1-1)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC681913  similar to Maleylacetoacetate isomerase (MAAI) (Glutathione S-transferase zeta 1) (GSTZ1-1)      Symbol and Name status set to provisional 70820 PROVISIONAL