Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | epigallocatechin gallate results in decreased expression of LRR1 mRNA | CTD | PMID:22079256 | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LRR1 mRNA | CTD | PMID:22079256 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of LRR1 mRNA | CTD | PMID:30723492 | 17beta-estradiol | increases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of LRR1 mRNA | CTD | PMID:19167446 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRR1 mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LRR1 mRNA | CTD | PMID:33387578 | 2,4-diaminotoluene | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | 2 and 4-diaminotoluene results in increased expression of LRR1 mRNA | CTD | PMID:20713471 | 3-methylcholanthrene | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Methylcholanthrene results in increased expression of LRR1 mRNA | CTD | PMID:20713471 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of LRR1 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of LRR1 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of LRR1 mRNA | CTD | PMID:19770486 | arsenite(3-) | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to LRR1 mRNA] | CTD | PMID:32406909 | azathioprine | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Azathioprine results in decreased expression of LRR1 mRNA | CTD | PMID:22623647 | benzo[a]pyrene | affects methylation | ISO | LRR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LRR1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of LRR1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bis(2-chloroethyl) sulfide | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Mustard Gas results in decreased expression of LRR1 mRNA | CTD | PMID:25102026 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LRR1 mRNA | CTD | PMID:25181051 more ... | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LRR1 mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of LRR1 mRNA | CTD | PMID:29275510 | cadmium atom | increases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Cadmium results in increased expression of LRR1 mRNA | CTD | PMID:24376830 | calcitriol | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of LRR1 mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of LRR1 mRNA | CTD | PMID:21592394 | carbon nanotube | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LRR1 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of LRR1 mRNA | CTD | PMID:37019170 | copper(II) sulfate | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of LRR1 mRNA | CTD | PMID:19549813 | coumestrol | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | coumestrol | increases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of LRR1 mRNA | CTD | PMID:19167446 | cyclosporin A | affects expression | ISO | LRR1 (Homo sapiens) | 6480464 | Cyclosporine affects the expression of LRR1 mRNA | CTD | PMID:25562108 | diazinon | increases methylation | ISO | LRR1 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of LRR1 gene | CTD | PMID:22964155 | dicrotophos | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of LRR1 mRNA | CTD | PMID:28302478 | dioxygen | decreases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Oxygen deficiency results in decreased expression of LRR1 mRNA | CTD | PMID:24205000 | dioxygen | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of LRR1 mRNA | CTD | PMID:26516004 | Enterolactone | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LRR1 mRNA | CTD | PMID:19167446 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of LRR1 mRNA | CTD | PMID:33387578 | lead(0) | increases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Lead results in increased expression of LRR1 mRNA | CTD | PMID:19921347 | leflunomide | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of LRR1 mRNA | CTD | PMID:28988120 | lidocaine | increases expression | EXP | | 6480464 | Lidocaine results in increased expression of LRR1 mRNA | CTD | PMID:35283115 | nickel atom | increases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Nickel results in increased expression of LRR1 mRNA | CTD | PMID:25583101 | ozone | multiple interactions | ISO | Lrr1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of LRR1 mRNA | CTD | PMID:27106289 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of LRR1 mRNA | CTD | PMID:33387578 | perfluorooctanoic acid | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of LRR1 mRNA | CTD | PMID:36326898 | phenethyl isothiocyanate | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | phenethyl isothiocyanate results in decreased expression of LRR1 mRNA | CTD | PMID:26678675 | phenobarbital | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of LRR1 mRNA | CTD | PMID:23091169 | pirinixic acid | multiple interactions | ISO | Lrr1 (Mus musculus) | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of LRR1 mRNA | CTD | PMID:20813756 | pirinixic acid | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of LRR1 mRNA | CTD | PMID:20813756 | potassium chromate | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LRR1 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of LRR1 mRNA | CTD | PMID:22079256 | resveratrol | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with Resveratrol] results in increased expression of LRR1 mRNA and [Plant Extracts co-treated with Resveratrol] results in increased expression of LRR1 mRNA | CTD | PMID:19167446 and PMID:23557933 | silicon dioxide | decreases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of LRR1 mRNA | CTD | PMID:19073995 | sodium arsenite | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of LRR1 mRNA | CTD | PMID:37682722 | sunitinib | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of LRR1 mRNA | CTD | PMID:31533062 | testosterone | decreases expression | ISO | LRR1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of LRR1 mRNA | CTD | PMID:21592394 | testosterone | multiple interactions | ISO | LRR1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of LRR1 mRNA | CTD | PMID:21592394 | tetrachloromethane | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of LRR1 mRNA | CTD | PMID:31919559 | thalidomide | decreases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Thalidomide results in decreased expression of LRR1 mRNA | CTD | PMID:26217789 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of LRR1 mRNA | CTD | PMID:33387578 | trimellitic anhydride | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of LRR1 mRNA | CTD | PMID:19042947 | tungsten | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Tungsten results in increased expression of LRR1 mRNA | CTD | PMID:30912803 | valproic acid | increases expression | ISO | Lrr1 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of LRR1 mRNA | CTD | PMID:21427059 | |