Dedd2 (death effector domain containing 2) - Rat Genome Database

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Gene: Dedd2 (death effector domain containing 2) Rattus norvegicus
Analyze
Symbol: Dedd2
Name: death effector domain containing 2
RGD ID: 1588968
Description: Predicted to enable DNA binding activity. Predicted to be involved in apoptotic nuclear changes; extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human DEDD2 (death effector domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA-binding death effector domain-containing protein 2; LOC687118; similar to death effector domain-containing DNA binding protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,916,906 - 89,934,663 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl189,919,524 - 89,936,804 (-)EnsemblGRCr8
mRatBN7.2180,789,084 - 80,807,789 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,792,000 - 80,807,714 (-)EnsemblmRatBN7.2
Dahl_SR_JrHsd188,536,856 - 88,555,364 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive193,673,679 - 93,692,187 (-)NCBILyon_Normotensive
Lyon_Hypertensive190,217,684 - 90,236,185 (-)NCBILyon_Hypertensive
F344_StmMcwi188,662,140 - 88,680,648 (-)NCBIF344_StmMcwi
Rnor_6.0182,073,024 - 82,089,028 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,072,544 - 82,088,275 (-)Ensemblrn6Rnor6.0
Rnor_5.0183,341,497 - 83,357,501 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera175,235,627 - 75,251,267 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crotonaldehyde  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
disulfiram  (ISO)
diuron  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
motexafin gadolinium  (ISO)
nitrates  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
rac-lactic acid  (ISO)
sanguinarine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (IBA,IEA,ISO)

Molecular Function
DNA binding  (IBA,IEA)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11741985   PMID:35416722  


Genomics

Comparative Map Data
Dedd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,916,906 - 89,934,663 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl189,919,524 - 89,936,804 (-)EnsemblGRCr8
mRatBN7.2180,789,084 - 80,807,789 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,792,000 - 80,807,714 (-)EnsemblmRatBN7.2
Dahl_SR_JrHsd188,536,856 - 88,555,364 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive193,673,679 - 93,692,187 (-)NCBILyon_Normotensive
Lyon_Hypertensive190,217,684 - 90,236,185 (-)NCBILyon_Hypertensive
F344_StmMcwi188,662,140 - 88,680,648 (-)NCBIF344_StmMcwi
Rnor_6.0182,073,024 - 82,089,028 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,072,544 - 82,088,275 (-)Ensemblrn6Rnor6.0
Rnor_5.0183,341,497 - 83,357,501 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera175,235,627 - 75,251,267 (-)NCBICelera
Cytogenetic Map1q21NCBI
DEDD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381942,198,598 - 42,220,134 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1942,198,593 - 42,220,140 (-)Ensemblhg38GRCh38
GRCh371942,702,750 - 42,724,286 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,394,592 - 47,413,653 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341947,394,591 - 47,413,653NCBI
Celera1939,503,547 - 39,522,608 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1939,133,170 - 39,154,731 (-)NCBIHuRef
CHM1_11942,704,403 - 42,725,961 (-)NCBICHM1_1
T2T-CHM13v2.01945,017,972 - 45,039,508 (-)NCBIT2T-CHM13v2.0
Dedd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,899,337 - 24,920,035 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,899,340 - 24,920,040 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38725,199,912 - 25,220,614 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,199,915 - 25,220,615 (-)Ensemblmm10GRCm38
MGSCv37725,987,859 - 26,004,878 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36724,911,598 - 24,928,607 (-)NCBIMGSCv36mm8
Celera719,818,126 - 19,835,162 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.73NCBI
Dedd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555684,523 - 701,915 (+)Ensembl
ChiLan1.0NW_004955555684,523 - 701,915 (+)NCBIChiLan1.0ChiLan1.0
DEDD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22048,303,991 - 48,325,628 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11950,172,609 - 50,194,190 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01939,086,735 - 39,108,312 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,678,915 - 47,700,442 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,678,915 - 47,700,431 (-)EnsemblpanPan2panpan1.1
DEDD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,148,146 - 112,164,473 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,148,925 - 112,163,770 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1111,573,894 - 111,590,243 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01112,760,371 - 112,776,720 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,760,449 - 112,776,717 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,314,570 - 112,330,919 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,950,500 - 111,966,845 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,877,065 - 112,893,414 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dedd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,938,497 - 15,955,571 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706285,820 - 305,869 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936706285,874 - 302,910 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEDD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,710,933 - 49,727,192 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1649,710,948 - 49,730,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,629,674 - 45,646,520 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DEDD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,402,615 - 36,423,250 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,402,614 - 36,422,509 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607314,646,887 - 14,669,527 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dedd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907531,016 - 547,256 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624907531,011 - 547,256 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dedd2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12169,494,089 - 169,509,593 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dedd2
32 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:102
Count of miRNA genes:77
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000072616
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat

Markers in Region
RH134458  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2180,792,012 - 80,792,205 (+)MAPPERmRatBN7.2
Rnor_6.0182,073,046 - 82,073,238NCBIRnor6.0
Rnor_5.0183,341,519 - 83,341,711UniSTSRnor5.0
Celera175,235,649 - 75,235,841UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000072616   ⟹   ENSRNOP00000065537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl189,919,524 - 89,936,804 (-)Ensembl
mRatBN7.2 Ensembl180,792,000 - 80,807,714 (-)Ensembl
Rnor_6.0 Ensembl182,072,544 - 82,088,275 (-)Ensembl
RefSeq Acc Id: NM_001432582   ⟹   NP_001419511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd188,536,856 - 88,555,364 (-)NCBI
Lyon_Normotensive193,673,679 - 93,692,187 (-)NCBI
Lyon_Hypertensive190,217,684 - 90,236,185 (-)NCBI
F344_StmMcwi188,662,140 - 88,680,648 (-)NCBI
RefSeq Acc Id: NR_197299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd188,536,856 - 88,555,364 (-)NCBI
Lyon_Normotensive193,673,679 - 93,692,187 (-)NCBI
Lyon_Hypertensive190,217,684 - 90,236,185 (-)NCBI
F344_StmMcwi188,662,140 - 88,680,648 (-)NCBI
RefSeq Acc Id: NR_197300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd188,536,856 - 88,555,364 (-)NCBI
Lyon_Normotensive193,673,679 - 93,692,187 (-)NCBI
Lyon_Hypertensive190,217,684 - 90,236,185 (-)NCBI
F344_StmMcwi188,662,140 - 88,680,648 (-)NCBI
RefSeq Acc Id: NR_197301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd188,536,856 - 88,555,364 (-)NCBI
Lyon_Normotensive193,673,679 - 93,692,187 (-)NCBI
Lyon_Hypertensive190,217,684 - 90,236,185 (-)NCBI
F344_StmMcwi188,662,140 - 88,680,648 (-)NCBI
RefSeq Acc Id: XM_003748789   ⟹   XP_003748837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,916,906 - 89,934,663 (-)NCBI
mRatBN7.2180,789,084 - 80,807,789 (-)NCBI
Rnor_6.0182,073,024 - 82,089,028 (-)NCBI
Rnor_5.0183,341,497 - 83,357,501 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005493775
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,920,859 - 89,934,663 (-)NCBI
mRatBN7.2180,792,958 - 80,807,789 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001419511 (Get FASTA)   NCBI Sequence Viewer  
  XP_003748837 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM08040 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065537.2
RefSeq Acc Id: XP_003748837   ⟸   XM_003748789
- Sequence:
Ensembl Acc Id: ENSRNOP00000065537   ⟸   ENSRNOT00000072616
RefSeq Acc Id: NP_001419511   ⟸   NM_001432582
Protein Domains
DED

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R7V1-F1-model_v2 AlphaFold M0R7V1 1-331 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1588968 AgrOrtholog
BioCyc Gene G2FUF-60400 BioCyc
Ensembl Genes ENSRNOG00000046112 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072616.4 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
InterPro DEATH-like_dom UniProtKB/TrEMBL
  DED UniProtKB/TrEMBL
  DEDD/DEDD2 UniProtKB/TrEMBL
  TRADD-like_N UniProtKB/TrEMBL
KEGG Report rno:687118 UniProtKB/TrEMBL
NCBI Gene 687118 ENTREZGENE
PANTHER DNA-BINDING DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  PTHR15205 UniProtKB/TrEMBL
Pfam DED UniProtKB/TrEMBL
  TRADD-like_N UniProtKB/TrEMBL
PhenoGen Dedd2 PhenoGen
PROSITE DED UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046112 RatGTEx
SMART DED UniProtKB/TrEMBL
Superfamily-SCOP DEATH_like UniProtKB/TrEMBL
UniProt A6J943 ENTREZGENE, UniProtKB/TrEMBL
  M0R7V1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-16 Dedd2  death effector domain containing 2  LOC687118  similar to death effector domain-containing DNA binding protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC687118  similar to death effector domain-containing DNA binding protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL