Usp21 (ubiquitin specific peptidase 21) - Rat Genome Database

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Gene: Usp21 (ubiquitin specific peptidase 21) Rattus norvegicus
Analyze
Symbol: Usp21
Name: ubiquitin specific peptidase 21
RGD ID: 1588822
Description: Predicted to enable cysteine-type deubiquitinase activity; deNEDDylase activity; and transcription coactivator activity. Involved in neuron projection development. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human USP21 (ubiquitin specific peptidase 21); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: deubiquitinating enzyme 21; LOC688466; MGC187584; similar to Ubiquitin carboxyl-terminal hydrolase 21 (Ubiquitin thiolesterase 21) (Ubiquitin-specific processing protease 21) (Deubiquitinating enzyme 21); ubiquitin carboxyl-terminal hydrolase 21; ubiquitin thioesterase 21; ubiquitin thiolesterase 21; ubiquitin-specific protease 21; ubiquitin-specific-processing protease 21
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,235,122 - 86,241,663 (-)NCBIGRCr8
mRatBN7.21383,702,672 - 83,709,215 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,702,631 - 83,708,717 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,208,448 - 86,214,501 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,606,655 - 87,612,708 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,838,118 - 84,844,154 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,655,016 - 89,661,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,655,064 - 89,661,150 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,281,882 - 94,288,016 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,175,527 - 87,181,024 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1383,333,270 - 83,339,404 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)
plasma membrane  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. H2A-DUBbing the mammalian epigenome: expanding frontiers for histone H2A deubiquitinating enzymes in cell biology and physiology. Belle JI and Nijnik A, Int J Biochem Cell Biol. 2014 May;50:161-74. doi: 10.1016/j.biocel.2014.03.004. Epub 2014 Mar 16.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
5. Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions. Urbe S, etal., Mol Biol Cell. 2012 Mar;23(6):1095-103. doi: 10.1091/mbc.E11-08-0668. Epub 2012 Feb 1.
Additional References at PubMed
PMID:10799498   PMID:12477932   PMID:18172164   PMID:26100909  


Genomics

Comparative Map Data
Usp21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,235,122 - 86,241,663 (-)NCBIGRCr8
mRatBN7.21383,702,672 - 83,709,215 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,702,631 - 83,708,717 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,208,448 - 86,214,501 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,606,655 - 87,612,708 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,838,118 - 84,844,154 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,655,016 - 89,661,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,655,064 - 89,661,150 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,281,882 - 94,288,016 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,175,527 - 87,181,024 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1383,333,270 - 83,339,404 (-)NCBICelera
Cytogenetic Map13q24NCBI
USP21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,159,500 - 161,165,723 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,159,450 - 161,165,723 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,129,290 - 161,135,513 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,395,878 - 159,402,140 (+)NCBINCBI36Build 36hg18NCBI36
Build 341157,942,346 - 157,948,580NCBI
Celera1134,196,407 - 134,202,669 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,486,196 - 132,492,458 (+)NCBIHuRef
CHM1_11162,525,504 - 162,531,766 (+)NCBICHM1_1
T2T-CHM13v2.01160,296,946 - 160,303,180 (+)NCBIT2T-CHM13v2.0
Usp21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,109,523 - 171,115,534 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,109,519 - 171,115,564 (-)EnsemblGRCm39 Ensembl
GRCm381171,281,949 - 171,287,961 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,281,945 - 171,287,991 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,212,080 - 173,218,092 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,118,624 - 173,124,623 (-)NCBIMGSCv36mm8
Celera1173,737,971 - 173,743,991 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.3NCBI
Usp21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,924,574 - 12,929,497 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,923,121 - 12,929,780 (+)NCBIChiLan1.0ChiLan1.0
USP21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,686,245 - 88,692,269 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,376,566 - 88,382,793 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,571,967 - 136,578,196 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,484,742 - 140,491,014 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,484,742 - 140,491,004 (+)Ensemblpanpan1.1panPan2
USP21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,311,859 - 21,318,414 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,311,859 - 21,320,106 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,386,438 - 21,392,779 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,429,424 - 21,436,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,429,424 - 21,437,732 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,317,263 - 21,324,003 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,731,698 - 21,738,410 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,140,841 - 22,147,481 (-)NCBIUU_Cfam_GSD_1.0
Usp21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,253,974 - 7,260,943 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903464,353 - 469,345 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903462,617 - 469,592 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,289,070 - 89,295,237 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,289,056 - 89,295,232 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,145,780 - 97,152,902 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,820,012 - 2,826,817 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,820,333 - 2,825,131 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,867,141 - 1,873,408 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794216,951 - 223,269 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794216,668 - 223,259 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Usp21
17 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:275
Count of miRNA genes:162
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000058390
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

Markers in Region
W53272  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,703,257 - 83,703,366 (+)MAPPERmRatBN7.2
Rnor_6.01389,655,691 - 89,655,799NCBIRnor6.0
Rnor_5.01394,282,557 - 94,282,665UniSTSRnor5.0
RGSC_v3.41387,176,203 - 87,176,311UniSTSRGSC3.4
Celera1383,333,945 - 83,334,053UniSTS
Cytogenetic Map13q24UniSTS
RH127964  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,709,430 - 83,709,639 (+)MAPPERmRatBN7.2
Rnor_6.01389,661,864 - 89,662,072NCBIRnor6.0
Rnor_5.01394,288,730 - 94,288,938UniSTSRnor5.0
RGSC_v3.41387,181,738 - 87,181,946UniSTSRGSC3.4
Celera1383,340,118 - 83,340,326UniSTS
RH 3.4 Map13552.5UniSTS
Cytogenetic Map13q24UniSTS
BI294933  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,704,593 - 83,704,761 (+)MAPPERmRatBN7.2
Rnor_6.01389,657,027 - 89,657,194NCBIRnor6.0
Rnor_5.01394,283,893 - 94,284,060UniSTSRnor5.0
Celera1383,335,281 - 83,335,448UniSTS
RH 3.4 Map13564.8UniSTS
Cytogenetic Map13q24UniSTS
BF405831  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,702,405 - 83,702,559 (+)MAPPERmRatBN7.2
Rnor_6.01389,654,838 - 89,654,991NCBIRnor6.0
Rnor_5.01394,281,704 - 94,281,857UniSTSRnor5.0
RGSC_v3.41387,175,349 - 87,175,502UniSTSRGSC3.4
Celera1383,333,092 - 83,333,245UniSTS
RH 3.4 Map13568.4UniSTS
Cytogenetic Map13q24UniSTS
RH139112  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,710,435 - 83,710,691 (+)MAPPERmRatBN7.2
Rnor_6.01389,662,869 - 89,663,124NCBIRnor6.0
Rnor_5.01394,289,735 - 94,289,990UniSTSRnor5.0
RGSC_v3.41387,182,743 - 87,182,998UniSTSRGSC3.4
Celera1383,341,123 - 83,341,378UniSTS
RH 3.4 Map13552.3UniSTS
Cytogenetic Map13q24UniSTS
G43283  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,702,692 - 83,702,832 (+)MAPPERmRatBN7.2
Rnor_6.01389,655,126 - 89,655,265NCBIRnor6.0
Rnor_5.01394,281,992 - 94,282,131UniSTSRnor5.0
RGSC_v3.41387,175,637 - 87,175,776UniSTSRGSC3.4
Celera1383,333,380 - 83,333,519UniSTS
Cytogenetic Map13q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 49 33 19 33 3 73 32 40 11
Low 8 8 8 8 8 8 1 3 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000058390   ⟹   ENSRNOP00000055192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,702,681 - 83,708,717 (-)Ensembl
Rnor_6.0 Ensembl1389,655,064 - 89,661,150 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100554   ⟹   ENSRNOP00000084677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,702,631 - 83,708,577 (-)Ensembl
RefSeq Acc Id: NM_001127638   ⟹   NP_001121110
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,235,127 - 86,241,180 (-)NCBI
mRatBN7.21383,702,677 - 83,708,730 (-)NCBI
Rnor_6.01389,655,016 - 89,661,150 (-)NCBI
Rnor_5.01394,281,882 - 94,288,016 (-)NCBI
RGSC_v3.41387,175,527 - 87,181,024 (-)RGD
Celera1383,333,270 - 83,339,404 (-)RGD
Sequence:
RefSeq Acc Id: XM_063272618   ⟹   XP_063128688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,235,122 - 86,240,969 (-)NCBI
RefSeq Acc Id: XR_010056937
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,235,122 - 86,241,663 (-)NCBI
RefSeq Acc Id: XR_010056938
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,235,122 - 86,239,422 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001121110 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128688 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66443 (Get FASTA)   NCBI Sequence Viewer  
  B2GUX4 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000055192
  ENSRNOP00000055192.4
  ENSRNOP00000084677.1
Reference Protein Sequences
RefSeq Acc Id: NP_001121110   ⟸   NM_001127638
- UniProtKB: B2GUX4 (UniProtKB/Swiss-Prot),   A0A8I6A1T1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000055192   ⟸   ENSRNOT00000058390
RefSeq Acc Id: ENSRNOP00000084677   ⟸   ENSRNOT00000100554
RefSeq Acc Id: XP_063128688   ⟸   XM_063272618
- Peptide Label: isoform X1
Protein Domains
USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2GUX4-F1-model_v2 AlphaFold B2GUX4 1-565 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699001
Promoter ID:EPDNEW_R9526
Type:multiple initiation site
Name:Usp21_1
Description:ubiquitin specific peptidase 21
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01389,661,148 - 89,661,208EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1588822 AgrOrtholog
BioCyc Gene G2FUF-17377 BioCyc
Ensembl Genes ENSRNOG00000038347 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058390 ENTREZGENE
  ENSRNOT00000058390.4 UniProtKB/TrEMBL
  ENSRNOT00000100554.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8363035 IMAGE-MGC_LOAD
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:688466 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187584 IMAGE-MGC_LOAD
NCBI Gene 688466 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Usp21 PhenoGen
PROSITE USP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000038347 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A1T1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QT23_RAT UniProtKB/TrEMBL
  A6JFW8_RAT UniProtKB/TrEMBL
  B2GUX4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-15 Usp21  ubiquitin specific peptidase 21  LOC688466  similar to Ubiquitin carboxyl-terminal hydrolase 21 (Ubiquitin thiolesterase 21) (Ubiquitin-specific processing protease 21) (Deubiquitinating enzyme 21)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC688466  similar to Ubiquitin carboxyl-terminal hydrolase 21 (Ubiquitin thiolesterase 21) (Ubiquitin-specific processing protease 21) (Deubiquitinating enzyme 21)      Symbol and Name status set to provisional 70820 PROVISIONAL