Ext1 Rat Gene (exostoses (multiple) 1)

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Keyword

Gene:
Ext1 ( Rattus norvegicus )
exostoses (multiple) 1
Description: mutations of the human homolog are associated with multiple exostoses type I and chondrosarcoma
Synonyms: similar to Ext1; LOC299907;  (details...)
ArrayIDs: 1392083_at; 5916509; 5925183; 6158446; 5634716; GE1197607; 6153137; A_44_P183137; 5986868; 1373393_at; 5626922; 5624334; 6598282; 5982330; 5667954; 6661454; 5862698; 6055430; rc_AA858704_at; 6407688; 6484533; 6559128; 6360437; A_43_P18410; 5916588; 6645710; 6341769;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: EXT1     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Ext1     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Ext1 Rat Celera Assembly 7 81215845 - 81493769
RGSC genome assembly v3.4 7 89392841 - 89671499
Cytogenetic 7 q31
Mus musculus Ext1 Mouse genome assembly build 36.1 15 52899816 - 53177738
Cytogenetic 15 15 C
Homo sapiens EXT1 human genome assembly 8 118880786 - 119193239
Human genome assembly build 36.2 8 118880783 - 119193239
Cytogenetic 8 q24.11-q24.13

View comparative maps:      NCBI MapViewer

Genome
View:

Annotation
Molecular Function

Gene Ontology

protein homodimerization activity,  protein heterodimerization activity,  protein binding ... (details...)
Biological Process

Gene Ontology

biological_process,  ossification,  gastrulation ... (details...)
Cellular Component

Gene Ontology

membrane,  integral to endoplasmic reticulum membrane,  cellular_component (details...)
Disease

Ontology

Exostoses, Multiple Hereditary (details...)

External Links
Databases
DATABASE ID SOURCE
Ensembl Protein: ENSRNOP00000031943 IPI
IPI: IPI00370669 IPI
Entrez Gene: Ext1 ENTREZGENE
IMAGE_CLONE: IMAGE:7453681 IMAGE-MGC_LOAD
UNIPARC: UPI00000241A1 IPI
MGC_CLONE: MGC:125218 IMAGE-MGC_LOAD
KEGG Report: rno:299907 ENTREZGENE
Ensembl Genes: ENSRNOG00000024886 IPI
UniProt: Q3B8R0_RAT IPI
HomoloGene Group ID: 30957 ENTREZGENE
Pfam: Glyco_transf_64 IPI
Pfam: Exostosin IPI
KEGG Pathway: 00534 ENTREZGENE
KEGG Pathway: 01100 ENTREZGENE
InterPro: Exostosin. IPI
InterPro: HexNAc_Trfase_a. IPI
Sequences
Nucleotide: XM_216920 Get FASTA Search GEO Profiles
Nucleotide: XM_001065900 Get FASTA Search GEO Profiles
Nucleotide: AC106595 Get FASTA Search GEO Profiles
Nucleotide: AC123178 Get FASTA Search GEO Profiles
Nucleotide: CH473950 Get FASTA Search GEO Profiles
Nucleotide: BC105839 Get FASTA Search GEO Profiles
(View all 6 Nucleotide Accessions)
Protein: XP_001065900 Get FASTA
Protein: EDM16269 Get FASTA
Protein: XP_216920 Get FASTA
Protein: AAI05840 Get FASTA
Protein: Q3B8R0 Get FASTA
(View all 5 Protein Accessions)
Clusters
UniGene: 106323

References
Curated References
3 references in RGD related to Ext1

Other References
1 other references at PubMed related to Ext1

Database Information
RGD ID 1587375
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

04-MAR-08: Ext1 exostoses (multiple) 1 LOC299907 similar to Ext1 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863

19-NOV-06: LOC299907 similar to Ext1 PROVISIONAL Symbol and Name status set to provisional 70820