Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Unc5cl | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of UNC5CL mRNA] | CTD | PMID:31150632 | Unc5cl | Rat | 1,1-dichloroethene | increases expression | ISO | Unc5cl (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of UNC5CL mRNA | CTD | PMID:26682919 | Unc5cl | Rat | 1,2-dichloroethane | decreases expression | ISO | Unc5cl (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of UNC5CL mRNA | CTD | PMID:28960355 | Unc5cl | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of UNC5CL mRNA | CTD | PMID:25380136|PMID:30723492 | Unc5cl | Rat | 17beta-estradiol | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Estradiol results in decreased expression of UNC5CL mRNA | CTD | PMID:20106945 | Unc5cl | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of UNC5CL mRNA | CTD | PMID:32741896 | Unc5cl | Rat | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of UNC5CL mRNA | CTD | PMID:32741896 | Unc5cl | Rat | 2,3,4,7,8-Pentachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,4,7,8-pentachlorodibenzofuran results in decreased expression of UNC5CL mRNA | CTD | PMID:21724226 | Unc5cl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UNC5CL mRNA | CTD | PMID:20106945 | Unc5cl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UNC5CL mRNA | CTD | PMID:33387578 | Unc5cl | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of UNC5CL mRNA | CTD | PMID:21724226 | Unc5cl | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of UNC5CL mRNA | CTD | PMID:25380136 | Unc5cl | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Unc5cl (Mus musculus) | 6480464 | bisphenol S affects the methylation of UNC5CL gene | CTD | PMID:31683443 | Unc5cl | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Unc5cl (Mus musculus) | 6480464 | Fenretinide results in increased expression of UNC5CL mRNA | CTD | PMID:28973697 | Unc5cl | Rat | 6-propyl-2-thiouracil | multiple interactions | ISO | Unc5cl (Mus musculus) | 6480464 | [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of UNC5CL mRNA | CTD | PMID:36706583 | Unc5cl | Rat | aflatoxin B1 | increases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of UNC5CL mRNA | CTD | PMID:22100608 | Unc5cl | Rat | aflatoxin B1 | increases methylation | ISO | UNC5CL (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of UNC5CL polyA tail | CTD | PMID:30157460 | Unc5cl | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of UNC5CL mRNA | CTD | PMID:35163327 | Unc5cl | Rat | aristolochic acid A | increases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of UNC5CL mRNA | CTD | PMID:33212167 | Unc5cl | Rat | benzo[a]pyrene | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of UNC5CL mRNA | CTD | PMID:20106945 | Unc5cl | Rat | benzo[a]pyrene | affects methylation | ISO | UNC5CL (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of UNC5CL 3' UTR | CTD | PMID:27901495 | Unc5cl | Rat | benzo[a]pyrene | increases methylation | ISO | UNC5CL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of UNC5CL promoter | CTD | PMID:27901495 | Unc5cl | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of UNC5CL mRNA | CTD | PMID:25181051|PMID:32145629 | Unc5cl | Rat | bisphenol A | multiple interactions | ISO | UNC5CL (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of UNC5CL gene | CTD | PMID:31601247 | Unc5cl | Rat | bisphenol A | increases expression | ISO | Unc5cl (Mus musculus) | 6480464 | bisphenol A results in increased expression of UNC5CL mRNA | CTD | PMID:34585602 | Unc5cl | Rat | butanal | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of UNC5CL mRNA | CTD | PMID:26079696 | Unc5cl | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of UNC5CL promoter | CTD | PMID:22457795 | Unc5cl | Rat | cadmium dichloride | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of UNC5CL mRNA | CTD | PMID:38382870 | Unc5cl | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of UNC5CL mRNA | CTD | PMID:25993096 | Unc5cl | Rat | cisplatin | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of UNC5CL mRNA | CTD | PMID:27392435 | Unc5cl | Rat | cisplatin | multiple interactions | ISO | UNC5CL (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of UNC5CL mRNA | CTD | PMID:27392435 | Unc5cl | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of UNC5CL mRNA | CTD | PMID:24386269 | Unc5cl | Rat | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of UNC5CL mRNA | CTD | PMID:30556269 | Unc5cl | Rat | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of UNC5CL mRNA | CTD | PMID:30556269 | Unc5cl | Rat | cyclosporin A | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of UNC5CL mRNA | CTD | PMID:20106945|PMID:25562108|PMID:27989131 | Unc5cl | Rat | diiodine | multiple interactions | ISO | Unc5cl (Mus musculus) | 6480464 | [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of UNC5CL mRNA | CTD | PMID:36706583 | Unc5cl | Rat | dioxygen | increases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of UNC5CL mRNA | CTD | PMID:26516004 | Unc5cl | Rat | doxorubicin | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of UNC5CL mRNA | CTD | PMID:29803840 | Unc5cl | Rat | fulvestrant | multiple interactions | ISO | UNC5CL (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of UNC5CL gene | CTD | PMID:31601247 | Unc5cl | Rat | genistein | increases expression | ISO | Unc5cl (Mus musculus) | 6480464 | Genistein results in increased expression of UNC5CL mRNA | CTD | PMID:32186404 | Unc5cl | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of UNC5CL mRNA | CTD | PMID:33387578 | Unc5cl | Rat | GW 4064 | increases expression | ISO | Unc5cl (Mus musculus) | 6480464 | GW 4064 results in increased expression of UNC5CL mRNA | CTD | PMID:26655953 | Unc5cl | Rat | hydrogen peroxide | affects expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of UNC5CL mRNA | CTD | PMID:20044591 | Unc5cl | Rat | lead diacetate | multiple interactions | ISO | Unc5cl (Mus musculus) | 6480464 | [lead acetate results in increased abundance of Lead] which results in increased methylation of UNC5CL more ... | CTD | PMID:33445541 | Unc5cl | Rat | lead(0) | multiple interactions | ISO | Unc5cl (Mus musculus) | 6480464 | [lead acetate results in increased abundance of Lead] which results in increased methylation of UNC5CL more ... | CTD | PMID:33445541 | Unc5cl | Rat | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of UNC5CL mRNA | CTD | PMID:24136188 | Unc5cl | Rat | lidocaine | increases expression | EXP | | 6480464 | Lidocaine results in increased expression of UNC5CL mRNA | CTD | PMID:35283115 | Unc5cl | Rat | monosodium L-glutamate | decreases expression | ISO | Unc5cl (Mus musculus) | 6480464 | Sodium Glutamate results in decreased expression of UNC5CL mRNA | CTD | PMID:22078008 | Unc5cl | Rat | okadaic acid | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of UNC5CL mRNA | CTD | PMID:38832940 | Unc5cl | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of UNC5CL mRNA | CTD | PMID:25729387 | Unc5cl | Rat | paracetamol | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of UNC5CL mRNA | CTD | PMID:21420995|PMID:22230336 | Unc5cl | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of UNC5CL mRNA | CTD | PMID:33387578 | Unc5cl | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of UNC5CL mRNA | CTD | PMID:35163327 | Unc5cl | Rat | pirinixic acid | multiple interactions | ISO | UNC5CL (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Unc5cl | Rat | quercetin | increases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Quercetin results in increased expression of UNC5CL mRNA | CTD | PMID:21632981 | Unc5cl | Rat | S-(1,2-dichlorovinyl)-L-cysteine | increases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | S-(1,2-dichlorovinyl)cysteine results in increased expression of UNC5CL mRNA | CTD | PMID:35811015 | Unc5cl | Rat | silicon dioxide | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of UNC5CL mRNA | CTD | PMID:25895662 | Unc5cl | Rat | silicon dioxide | increases expression | ISO | Unc5cl (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of UNC5CL mRNA | CTD | PMID:29341224 | Unc5cl | Rat | sodium arsenite | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of UNC5CL mRNA | CTD | PMID:29301061 | Unc5cl | Rat | sodium arsenite | decreases expression | ISO | Unc5cl (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of UNC5CL mRNA | CTD | PMID:37682722 | Unc5cl | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of UNC5CL mRNA | CTD | PMID:25993096 | Unc5cl | Rat | sunitinib | increases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Sunitinib results in increased expression of UNC5CL mRNA | CTD | PMID:31533062 | Unc5cl | Rat | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of UNC5CL mRNA | CTD | PMID:32741896 | Unc5cl | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of UNC5CL mRNA] | CTD | PMID:31150632 | Unc5cl | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of UNC5CL mRNA | CTD | PMID:31150632 | Unc5cl | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of UNC5CL mRNA | CTD | PMID:23411599 | Unc5cl | Rat | titanium dioxide | decreases expression | ISO | Unc5cl (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of UNC5CL mRNA | CTD | PMID:29264374 | Unc5cl | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of UNC5CL mRNA | CTD | PMID:25729387 | Unc5cl | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of UNC5CL mRNA | CTD | PMID:25729387 | Unc5cl | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | UNC5CL (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of UNC5CL mRNA | CTD | PMID:29024780 | Unc5cl | Rat | urethane | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Urethane results in decreased expression of UNC5CL mRNA | CTD | PMID:28818685 | Unc5cl | Rat | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of UNC5CL mRNA | CTD | PMID:24136188 | Unc5cl | Rat | valproic acid | decreases expression | ISO | UNC5CL (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of UNC5CL mRNA | CTD | PMID:29154799 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















