Etaa1-ps1 (ETAA1 activator of ATR kinase, pseudogene 1) - Rat Genome Database

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Gene: Etaa1-ps1 (ETAA1 activator of ATR kinase, pseudogene 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Etaa1-ps1 (Ensembl: Etaa1l1)
Name: ETAA1 activator of ATR kinase, pseudogene 1 (Ensembl:ETAA1 activator of ATR kinase)
RGD ID: 1587340
Description:
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: Etaa1; ETAA1 activator of ATR kinase; Etaa1, ATR kinase activator; Ewing tumor-associated antigen 1; ewing's tumor-associated antigen 1 homolog; LOC316820; similar to ETAA16 protein
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Etaa1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8312,759,111 - 12,763,422 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2 Ensembl1492,299,553 - 92,314,104 (-)EnsemblmRatBN7.2
Rnor_6.014102,290,655 - 102,293,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14102,290,418 - 102,293,677 (-)Ensemblrn6Rnor6.0
Rnor_5.014102,044,751 - 102,052,740 (-)NCBIRnor_5.0Rnor_5.0rn5
Cytogenetic Map14q22NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:27723717   PMID:27723720  


Genomics

Variants

.
Variants in Etaa1-ps1
14 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:26
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000008135
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000008135   ⟹   ENSRNOP00000008135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1496,500,899 - 96,515,617 (-)Ensembl
mRatBN7.2 Ensembl1492,299,553 - 92,314,104 (-)Ensembl
Rnor_6.0 Ensembl14102,290,418 - 102,293,677 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097260   ⟹   ENSRNOP00000093008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1496,500,899 - 96,517,796 (-)Ensembl
mRatBN7.2 Ensembl1492,299,553 - 92,313,696 (-)Ensembl
RefSeq Acc Id: XM_229242   ⟹   XP_229242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014102,290,655 - 102,293,674 (-)NCBI
Rnor_5.014102,044,751 - 102,052,740 (-)NCBI
Sequence:
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQ67-F1-model_v2 AlphaFold D3ZQ67 1-872 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699516
Promoter ID:EPDNEW_R10029
Type:single initiation site
Name:Etaa1_1
Description:Etaa1, ATR kinase activator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014102,293,677 - 102,293,737EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1587340 AgrOrtholog
BioCyc Gene G2FUF-401 BioCyc
Ensembl Genes ENSRNOG00000006185 Ensembl
NCBI Gene 316820 ENTREZGENE
PhenoGen Etaa1-ps1 PhenoGen
RatGTEx ENSRNOG00000006185 RatGTEx


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-10 Etaa1-ps1  ETAA1 activator of ATR kinase, pseudogene 1  Etaa1  ETAA1 activator of ATR kinase  Name and Symbol changed 629549 APPROVED
2019-04-10 Etaa1  ETAA1 activator of ATR kinase  Etaa1  Etaa1, ATR kinase activator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-03-09 Etaa1  Etaa1, ATR kinase activator  Etaa1  Ewing tumor-associated antigen 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-18 Etaa1  Ewing tumor-associated antigen 1  LOC316820  similar to ETAA16 protein  Name and Symbol changed 629549 APPROVED
2006-11-19 LOC316820  similar to ETAA16 protein      Symbol and Name status set to provisional 70820 PROVISIONAL