C9h2orf66 (similar to human chromosome 2 open reading frame 66) - Rat Genome Database

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Gene: C9h2orf66 (similar to human chromosome 2 open reading frame 66) Rattus norvegicus
Analyze
Symbol: C9h2orf66 (Ensembl: LOC686030)
Name: similar to human chromosome 2 open reading frame 66 (Ensembl:predicted gene, 34066)
RGD ID: 1586666
Description: Orthologous to human C2orf66 (chromosome 2 open reading frame 66); INTERACTS WITH 1-Hydroxypyrene (ortholog); acrylamide (ortholog); aristolochic acid A (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC100365551; hypothetical protein LOC686030; LOC686030; uncharacterized protein C2orf66 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8963,440,494 - 63,444,210 (-)NCBIGRCr8
mRatBN7.2955,945,806 - 55,949,855 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl955,948,303 - 55,949,643 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0961,036,435 - 61,040,225 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0960,722,946 - 60,738,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4953,225,166 - 53,226,502 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera953,435,638 - 53,439,428 (-)NCBICelera
Cytogenetic Map9q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C9h2orf66
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8963,440,494 - 63,444,210 (-)NCBIGRCr8
mRatBN7.2955,945,806 - 55,949,855 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl955,948,303 - 55,949,643 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0961,036,435 - 61,040,225 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0960,722,946 - 60,738,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4953,225,166 - 53,226,502 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera953,435,638 - 53,439,428 (-)NCBICelera
Cytogenetic Map9q31NCBI
C2orf66
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382196,804,417 - 196,832,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2196,804,417 - 196,809,355 (-)EnsemblGRCh38hg38GRCh38
GRCh372197,669,141 - 197,674,079 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362197,378,254 - 197,383,245 (-)NCBINCBI36Build 36hg18NCBI36
Celera2191,425,877 - 191,430,868 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2189,521,761 - 189,527,630 (-)NCBIHuRef
CHM1_12197,674,991 - 197,680,852 (-)NCBICHM1_1
T2T-CHM13v2.02197,288,090 - 197,315,820 (-)NCBIT2T-CHM13v2.0
Gm34066
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39154,481,731 - 54,495,945 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl154,482,563 - 54,495,922 (-)EnsemblGRCm39 Ensembl
GRCm38154,442,572 - 54,456,786 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl154,443,404 - 54,456,763 (-)EnsemblGRCm38mm10GRCm38
MGSCv37154,501,638 - 54,503,022 (-)MERGEGRCm37MGSCv37mm9NCBIm37
Celera154,967,465 - 54,981,716 (-)NCBICelera
Cytogenetic Map1C1.2NCBI
CUNH2orf66
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554033,600,567 - 3,604,378 (+)NCBIChiLan1.0ChiLan1.0
C13H2orf66
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21399,424,004 - 99,439,884 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B99,438,995 - 99,448,905 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B84,048,089 - 84,055,991 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B201,949,363 - 201,951,884 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B201,949,363 - 201,951,310 (-)Ensemblpanpan1.1panPan2
C37H2orf66
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1376,403,572 - 6,407,464 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl376,403,548 - 6,407,323 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha377,350,789 - 7,356,240 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0376,293,422 - 6,298,868 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl376,295,814 - 6,297,663 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1376,293,023 - 6,298,472 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0376,262,642 - 6,265,833 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0376,284,397 - 6,287,994 (-)NCBIUU_Cfam_GSD_1.0
CUNH2orf66
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303154,502,516 - 154,507,591 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365062,323,711 - 2,333,346 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C15H2orf66
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15100,704,641 - 100,713,581 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115100,704,142 - 100,708,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215111,764,058 - 111,768,293 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH2orf66
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11082,327,616 - 82,332,630 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1082,327,626 - 82,334,450 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040117,105,614 - 117,128,820 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in C9h2orf66
31 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)94996854671098346Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000098126   ⟹   ENSRNOP00000088114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl955,948,303 - 55,949,643 (-)Ensembl
RefSeq Acc Id: XM_063268122   ⟹   XP_063124192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8963,440,494 - 63,444,210 (-)NCBI
RefSeq Acc Id: XR_005489144
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8963,440,494 - 63,441,795 (-)NCBI
mRatBN7.2955,945,806 - 55,949,007 (-)NCBI
RefSeq Acc Id: XR_010054984
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8963,440,494 - 63,441,799 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001420272 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124192 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000088114.1
Ensembl Acc Id: ENSRNOP00000088114   ⟸   ENSRNOT00000098126
RefSeq Acc Id: XP_063124192   ⟸   XM_063268122

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586666 AgrOrtholog
BioCyc Gene G2FUF-27543 BioCyc
Ensembl Genes ENSRNOG00000067303 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098126.1 UniProtKB/TrEMBL
InterPro DUF4720 UniProtKB/TrEMBL
NCBI Gene 686030 ENTREZGENE
PANTHER GENE, 34066-RELATED UniProtKB/TrEMBL
  PTHR47620 UniProtKB/TrEMBL
Pfam DUF4720 UniProtKB/TrEMBL
PhenoGen C9h2orf66 PhenoGen
RatGTEx ENSRNOG00000067303 RatGTEx
UniProt A0A8I6A4F4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C9h2orf66  similar to human chromosome 2 open reading frame 66  LOC686030  hypothetical protein LOC686030  Symbol and Name Changed 1299863 APPROVED
2013-05-24 LOC686030  hypothetical protein LOC686030  LOC100365551  hypothetical protein LOC100365551  Data merged from RGD:2318831 1643240 APPROVED
2010-05-05 LOC100365551  hypothetical protein LOC100365551      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC686030  hypothetical protein LOC686030  LOC683525  hypothetical protein LOC683525  Data merged from RGD:1585668 1643240 APPROVED
2006-11-19 LOC686030  hypothetical protein LOC686030      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683525  hypothetical protein LOC683525      Symbol and Name status set to provisional 70820 PROVISIONAL