Zfp185 (zinc finger protein 185) - Rat Genome Database

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Pathways
Gene: Zfp185 (zinc finger protein 185) Rattus norvegicus
Analyze
Symbol: Zfp185
Name: zinc finger protein 185
RGD ID: 1586351
Description: Predicted to enable metal ion binding activity. Orthologous to human ZNF185 (zinc finger protein 185 with LIM domain); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; methoxychlor.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC689949; similar to zinc finger protein 185
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X155,874,138 - 155,919,921 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX155,874,127 - 155,917,077 (+)EnsemblGRCr8
mRatBN7.2X150,831,869 - 150,877,652 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX150,831,862 - 150,874,810 (+)EnsemblmRatBN7.2
Rnor_6.0X152,989,099 - 153,034,289 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX152,999,016 - 153,031,444 (+)Ensemblrn6Rnor6.0
Rnor_5.01148,718,734 - 148,763,867 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X158,990,740 - 159,024,426 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1131,796,229 - 131,841,934 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:33450132  


Genomics

Comparative Map Data
Zfp185
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X155,874,138 - 155,919,921 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX155,874,127 - 155,917,077 (+)EnsemblGRCr8
mRatBN7.2X150,831,869 - 150,877,652 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX150,831,862 - 150,874,810 (+)EnsemblmRatBN7.2
Rnor_6.0X152,989,099 - 153,034,289 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX152,999,016 - 153,031,444 (+)Ensemblrn6Rnor6.0
Rnor_5.01148,718,734 - 148,763,867 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X158,990,740 - 159,024,426 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1131,796,229 - 131,841,934 (+)NCBICelera
Cytogenetic MapXq37NCBI
ZNF185
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X152,898,067 - 152,973,481 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX152,896,695 - 152,973,511 (+)Ensemblhg38GRCh38
GRCh37X152,066,611 - 152,142,025 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X151,833,653 - 151,892,678 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X151,757,232 - 151,812,583NCBI
CeleraX152,417,145 - 152,476,190 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX140,883,699 - 140,942,530 (+)NCBIHuRef
CHM1_1X151,957,910 - 152,016,969 (+)NCBICHM1_1
T2T-CHM13v2.0X151,164,487 - 151,239,920 (+)NCBIT2T-CHM13v2.0
Zfp185
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,030,860 - 72,075,149 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,030,945 - 72,075,149 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X72,987,252 - 73,031,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX72,987,339 - 73,031,543 (+)Ensemblmm10GRCm38
MGSCv37X70,232,678 - 70,276,882 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X69,250,502 - 69,284,232 (+)NCBIMGSCv36mm8
CeleraX63,910,727 - 63,955,718 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.29NCBI
Znf185
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554988,185,994 - 8,253,209 (+)Ensembl
ChiLan1.0NW_0049554988,185,997 - 8,248,910 (+)NCBIChiLan1.0ChiLan1.0
ZNF185
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X152,962,326 - 153,037,654 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X152,965,929 - 153,041,257 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X142,472,497 - 142,547,835 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X152,391,505 - 152,467,150 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX152,391,505 - 152,464,221 (+)EnsemblpanPan2panpan1.1
ZNF185
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X120,770,099 - 120,846,855 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX120,782,011 - 120,843,322 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX106,150,793 - 106,215,089 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X123,006,936 - 123,071,169 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX123,006,426 - 123,067,652 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X119,723,086 - 119,787,382 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X122,213,729 - 122,277,932 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X122,088,803 - 122,153,011 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Znf185
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X118,006,648 - 118,104,290 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936714152,319 - 218,921 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936714167,552 - 218,785 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF185
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX123,944,210 - 123,987,962 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X123,942,981 - 123,988,102 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X141,414,957 - 141,458,745 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF185
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X127,418,209 - 127,493,217 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606565,244,826 - 65,316,227 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf185
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248834,084,196 - 4,140,508 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248834,084,018 - 4,140,308 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Znf185
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X129,365,241 - 129,406,713 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:35
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000023109, ENSRNOT00000072259
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat

Markers in Region
D10Chm13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X150,854,528 - 150,854,728 (+)MAPPERmRatBN7.2
Rnor_6.0X153,011,166 - 153,011,365NCBIRnor6.0
Rnor_5.01148,740,744 - 148,740,943UniSTSRnor5.0
RGSC_v3.4X159,003,495 - 159,003,694UniSTSRGSC3.4
Celera1131,818,812 - 131,819,011UniSTS
Cytogenetic MapXq37UniSTS
U46687  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X150,875,530 - 150,875,623 (+)MAPPERmRatBN7.2
Rnor_6.0X153,032,168 - 153,032,260NCBIRnor6.0
Rnor_5.01148,761,746 - 148,761,838UniSTSRnor5.0
RGSC_v3.4X159,025,147 - 159,025,239UniSTSRGSC3.4
Celera1131,839,813 - 131,839,905UniSTS
Cytogenetic MapXq37UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 141 88 87 56 59 56 6 318 158 11 119 80 92 31 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000088234   ⟹   ENSRNOP00000069186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX155,874,127 - 155,917,077 (+)Ensembl
mRatBN7.2 EnsemblX150,831,862 - 150,874,810 (+)Ensembl
Rnor_6.0 EnsemblX152,999,016 - 153,031,444 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096881   ⟹   ENSRNOP00000087665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX155,874,127 - 155,917,077 (+)Ensembl
mRatBN7.2 EnsemblX150,831,862 - 150,874,810 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000151616   ⟹   ENSRNOP00000106478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX155,874,127 - 155,917,077 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000161009   ⟹   ENSRNOP00000110152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX155,887,768 - 155,917,077 (+)Ensembl
RefSeq Acc Id: XM_006229520   ⟹   XP_006229582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X155,874,139 - 155,919,921 (+)NCBI
mRatBN7.2X150,831,870 - 150,877,652 (+)NCBI
Rnor_6.0X152,989,100 - 153,034,289 (+)NCBI
Rnor_5.01148,718,734 - 148,763,867 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229522   ⟹   XP_006229584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X155,874,139 - 155,919,921 (+)NCBI
mRatBN7.2X150,831,869 - 150,877,652 (+)NCBI
Rnor_6.0X152,989,099 - 153,034,289 (+)NCBI
Rnor_5.01148,718,734 - 148,763,867 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602422   ⟹   XP_017457911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X155,883,336 - 155,919,921 (+)NCBI
mRatBN7.2X150,841,069 - 150,877,652 (+)NCBI
Rnor_6.0X152,996,235 - 153,034,289 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039100265   ⟹   XP_038956193
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X155,874,138 - 155,919,921 (+)NCBI
mRatBN7.2X150,831,869 - 150,877,652 (+)NCBI
RefSeq Acc Id: XP_006229582   ⟸   XM_006229520
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006229584   ⟸   XM_006229522
- Peptide Label: isoform X2
- UniProtKB: A6KSY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457911   ⟸   XM_017602422
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000069186   ⟸   ENSRNOT00000088234
RefSeq Acc Id: XP_038956193   ⟸   XM_039100265
- Peptide Label: isoform X3
- UniProtKB: A6KSY8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087665   ⟸   ENSRNOT00000096881
Ensembl Acc Id: ENSRNOP00000106478   ⟸   ENSRNOT00000151616
Ensembl Acc Id: ENSRNOP00000110152   ⟸   ENSRNOT00000161009
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JUQ6-F1-model_v2 AlphaFold A0A0G2JUQ6 1-483 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586351 AgrOrtholog
BioCyc Gene G2FUF-691 BioCyc
Ensembl Genes ENSRNOG00000051704 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000088234 ENTREZGENE
  ENSRNOT00000088234.3 UniProtKB/TrEMBL
  ENSRNOT00000096881.2 UniProtKB/TrEMBL
  ENSRNOT00000151616.1 UniProtKB/TrEMBL
  ENSRNOT00000161009.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro Cell_Prolif/Cornif_Regul UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
KEGG Report rno:689949 UniProtKB/TrEMBL
NCBI Gene 689949 ENTREZGENE
PANTHER PTHR15468:SF2 UniProtKB/TrEMBL
  ZNF185 UniProtKB/TrEMBL
PhenoGen Zfp185 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051704 RatGTEx
SMART LIM UniProtKB/TrEMBL
UniProt A0A0G2JUQ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AH10 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LWZ6_RAT UniProtKB/TrEMBL
  A0ABK0M784_RAT UniProtKB/TrEMBL
  A6KSY8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Zfp185  zinc finger protein 185  LOC689949  similar to zinc finger protein 185  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC689949  similar to zinc finger protein 185      Symbol and Name status set to provisional 70820 PROVISIONAL