Or2v2b (olfactory receptor family 2 subfamily V member 2B) - Rat Genome Database

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Gene: Or2v2b (olfactory receptor family 2 subfamily V member 2B) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or2v2b
Name: olfactory receptor family 2 subfamily V member 2B
RGD ID: 1586044
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be active in plasma membrane. Orthologous to human OR2V2 (olfactory receptor family 2 subfamily V member 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor family 2 subfamily V member 2; olfactory receptor gene Olr1384; olfactory receptor Olr1384; Olr1384; Or2v2
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81033,853,080 - 33,854,021 (-)NCBIGRCr8
mRatBN7.21033,351,954 - 33,352,895 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1033,349,460 - 33,353,999 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1038,043,529 - 38,044,470 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0106,581,941 - 6,582,882 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01033,037,171 - 33,038,112 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01034,332,364 - 34,333,305 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1034,332,364 - 34,333,305 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01034,114,412 - 34,115,353 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41034,251,973 - 34,252,914 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1032,739,648 - 32,740,589 (-)NCBICelera
Cytogenetic Map10q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or2v2bRatdetection of chemical stimulus involved in sensory perception of smell involved_inIBAMGI:106182 and PANTHER:PTN0028180001600115GO_REF:0000033GO_CentralGO_REF:0000033
Or2v2bRatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or2v2bRatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or2v2bRatsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or2v2bRatsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or2v2bRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or2v2bRatmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Or2v2bRatplasma membrane is_active_inIBAMGI:106648 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or2v2bRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Or2v2bRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or2v2bRatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or2v2bRatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or2v2bRatolfactory receptor activity enablesIBAMGI:106182 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or2v2bRatolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:15057822  



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Variants in Or2v2b
5 total Variants

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:30
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000071365
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat

1 to 10 of 51 rows



ectoderm
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
respiratory system
5 2 2 2 2 5 2


RefSeq Transcripts NM_001002291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC103024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000071365   ⟹   ENSRNOP00000067801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1034,332,364 - 34,333,305 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108609   ⟹   ENSRNOP00000095827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1033,349,460 - 33,353,999 (-)Ensembl
RefSeq Acc Id: NM_001002291   ⟹   NP_001002291
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81033,853,080 - 33,854,021 (-)NCBI
mRatBN7.21033,351,954 - 33,352,895 (-)NCBI
Rnor_6.01034,332,364 - 34,333,305 (-)NCBI
Rnor_5.01034,114,412 - 34,115,353 (-)NCBI
RGSC_v3.41034,251,973 - 34,252,914 (-)RGD
Celera1032,739,648 - 32,740,589 (-)RGD
Sequence:
Protein RefSeqs NP_001002291 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000095827.1
  ENSRNOP00000098760
RefSeq Acc Id: NP_001002291   ⟸   NM_001002291
- UniProtKB: A0A8I6APX4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067801   ⟸   ENSRNOT00000071365
Ensembl Acc Id: ENSRNOP00000095827   ⟸   ENSRNOT00000108609
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-M0RDU2-F1-model_v2 AlphaFold M0RDU2 1-313 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-25313 BioCyc
Ensembl Genes ENSRNOG00000047001 Ensembl
  ENSRNOG00000069499 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000089191 ENTREZGENE
Ensembl Transcript ENSRNOT00000108609.1 UniProtKB/TrEMBL
  ENSRNOT00000123654 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405398 UniProtKB/TrEMBL
NCBI Gene 405398 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2v2b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047001 RatGTEx
  ENSRNOG00000069499 RatGTEx
  ENSRNOG00000089191 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6APX4 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-05-14 Or2v2b  olfactory receptor family 2 subfamily V member 2B  Or2v2ret  olfactory receptor family 2 subfamily V member 2 retired  Name and Symbol changed 629549 APPROVED
2024-05-14 Or2v2ret  olfactory receptor family 2 subfamily V member 2 retired  Or2v2  olfactory receptor family 2 subfamily V member 2  Name and Symbol changed 629549 APPROVED
2022-08-16 Or2v2  olfactory receptor family 2 subfamily V member 2  Olr1384  olfactory receptor gene Olr1384  Symbol and Name Changed 1299863 APPROVED
2006-11-19 Olr1384  olfactory receptor gene Olr1384      Symbol and Name status set to provisional 70820 PROVISIONAL