Coq9 (coenzyme Q9) - Rat Genome Database

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Gene: Coq9 (coenzyme Q9) Rattus norvegicus
Analyze
Symbol: Coq9
Name: coenzyme Q9
RGD ID: 1586040
Description: Predicted to enable enzyme activator activity; isoprenoid binding activity; and protein homodimerization activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to act upstream of or within mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of ubiquinone biosynthesis complex. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 5. Orthologous to human COQ9 (coenzyme Q9); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: coenzyme Q9 homolog; coenzyme Q9 homolog (S. cerevisiae); LOC498909; similar to RIKEN cDNA 2310005O14; ubiquinone biosynthesis protein COQ9, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81910,172,943 - 10,185,960 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1910,172,949 - 10,185,937 (-)EnsemblGRCr8
mRatBN7.21910,166,948 - 10,179,976 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1910,166,951 - 10,179,949 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1910,131,050 - 10,144,018 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,897,894 - 10,910,862 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01910,184,842 - 10,197,810 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,583,855 - 10,596,848 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,583,857 - 10,596,851 (-)Ensemblrn6Rnor6.0
Rnor_5.01910,578,657 - 10,591,673 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41910,606,083 - 10,619,005 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1910,053,557 - 10,066,550 (-)NCBICelera
Cytogenetic Map19p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14651853   PMID:15057822   PMID:15489334   PMID:17824807   PMID:18614015   PMID:20833797   PMID:23255162   PMID:25339443  


Genomics

Comparative Map Data
Coq9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81910,172,943 - 10,185,960 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1910,172,949 - 10,185,937 (-)EnsemblGRCr8
mRatBN7.21910,166,948 - 10,179,976 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1910,166,951 - 10,179,949 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1910,131,050 - 10,144,018 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,897,894 - 10,910,862 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01910,184,842 - 10,197,810 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,583,855 - 10,596,848 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,583,857 - 10,596,851 (-)Ensemblrn6Rnor6.0
Rnor_5.01910,578,657 - 10,591,673 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41910,606,083 - 10,619,005 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1910,053,557 - 10,066,550 (-)NCBICelera
Cytogenetic Map19p13NCBI
COQ9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381657,447,479 - 57,461,270 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1657,447,425 - 57,461,274 (+)Ensemblhg38GRCh38
GRCh371657,481,391 - 57,495,182 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361656,038,903 - 56,052,680 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1641,982,201 - 41,996,039 (+)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1643,348,984 - 43,362,835 (+)NCBIHuRef
CHM1_11658,889,397 - 58,903,241 (+)NCBICHM1_1
T2T-CHM13v2.01663,242,655 - 63,256,447 (+)NCBIT2T-CHM13v2.0
Coq9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,565,041 - 95,581,523 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl895,564,949 - 95,581,523 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38894,838,413 - 94,854,895 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl894,838,321 - 94,854,895 (+)Ensemblmm10GRCm38
MGSCv37897,362,317 - 97,378,795 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36897,727,546 - 97,744,024 (+)NCBIMGSCv36mm8
Celera899,162,261 - 99,179,505 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.89NCBI
Coq9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,081,390 - 15,094,441 (+)Ensembl
ChiLan1.0NW_00495543315,081,390 - 15,094,441 (+)NCBIChiLan1.0ChiLan1.0
COQ9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21866,917,691 - 66,931,545 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11672,838,564 - 72,852,419 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01637,723,452 - 37,737,327 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11656,856,401 - 56,870,260 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1656,856,401 - 56,870,260 (+)EnsemblpanPan2panpan1.1
COQ9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,964,221 - 58,977,589 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,964,318 - 58,977,573 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha255,593,687 - 55,607,649 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0259,502,901 - 59,516,434 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl259,502,646 - 59,516,061 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1256,333,956 - 56,347,384 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0257,341,652 - 57,355,632 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,235,112 - 58,249,092 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Coq9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934950,071,474 - 50,086,451 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364759,502,681 - 9,516,936 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364759,502,638 - 9,517,601 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COQ9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,372,711 - 19,390,820 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1619,373,052 - 19,390,738 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,363,400 - 17,381,054 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COQ9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,378,467 - 43,393,037 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl543,378,539 - 43,392,384 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604732,826,053 - 32,840,619 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Coq9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474628,615,215 - 28,630,667 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474628,614,589 - 28,630,774 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Coq9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1171,718,468 - 1,731,647 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Coq9
89 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:319
Count of miRNA genes:203
Interacting mature miRNAs:241
Transcripts:ENSRNOT00000021716
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131969901Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124694445Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127361636Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
RH131810  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21910,167,225 - 10,167,431 (+)MAPPERmRatBN7.2
Rnor_6.01910,584,133 - 10,584,338NCBIRnor6.0
Rnor_5.01910,578,935 - 10,579,140UniSTSRnor5.0
RGSC_v3.41910,606,361 - 10,606,566UniSTSRGSC3.4
Celera1910,053,835 - 10,054,040UniSTS
RH 3.4 Map1973.13UniSTS
Cytogenetic Map19p12UniSTS
RH143876  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21910,167,044 - 10,167,223 (+)MAPPERmRatBN7.2
Rnor_6.01910,583,952 - 10,584,130NCBIRnor6.0
Rnor_5.01910,578,754 - 10,578,932UniSTSRnor5.0
RGSC_v3.41910,606,180 - 10,606,358UniSTSRGSC3.4
Celera1910,053,654 - 10,053,832UniSTS
RH 3.4 Map1993.41UniSTS
Cytogenetic Map19p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000021716   ⟹   ENSRNOP00000021716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1910,172,949 - 10,185,937 (-)Ensembl
mRatBN7.2 Ensembl1910,166,957 - 10,179,948 (-)Ensembl
Rnor_6.0 Ensembl1910,583,857 - 10,596,851 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094912   ⟹   ENSRNOP00000078182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1910,173,083 - 10,185,937 (-)Ensembl
mRatBN7.2 Ensembl1910,166,951 - 10,179,949 (-)Ensembl
RefSeq Acc Id: NM_001035257   ⟹   NP_001030334
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,172,943 - 10,185,936 (-)NCBI
mRatBN7.21910,166,948 - 10,179,943 (-)NCBI
Rnor_6.01910,583,855 - 10,596,848 (-)NCBI
Rnor_5.01910,578,657 - 10,591,673 (-)NCBI
RGSC_v3.41910,606,083 - 10,619,005 (-)RGD
Celera1910,053,557 - 10,066,550 (-)RGD
Sequence:
RefSeq Acc Id: XM_039097916   ⟹   XP_038953844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,172,943 - 10,185,960 (-)NCBI
mRatBN7.21910,166,948 - 10,179,976 (-)NCBI
RefSeq Acc Id: NP_001030334   ⟸   NM_001035257
- Peptide Label: precursor
- UniProtKB: A1L109 (UniProtKB/Swiss-Prot),   Q68FT1 (UniProtKB/Swiss-Prot),   A0A8L2UJQ7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021716   ⟸   ENSRNOT00000021716
RefSeq Acc Id: XP_038953844   ⟸   XM_039097916
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000078182   ⟸   ENSRNOT00000094912
Protein Domains
COQ9 C-terminal   Ubiquinone biosynthesis protein COQ9 HTH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q68FT1-F1-model_v2 AlphaFold Q68FT1 1-312 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700939
Promoter ID:EPDNEW_R11463
Type:multiple initiation site
Name:Coq9_1
Description:coenzyme Q9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01910,596,854 - 10,596,914EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586040 AgrOrtholog
BioCyc Gene G2FUF-6516 BioCyc
Ensembl Genes ENSRNOG00000016190 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021716 ENTREZGENE
  ENSRNOT00000094912.1 UniProtKB/Swiss-Prot
Gene3D-CATH Tetracycline Repressor, domain 2 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7109832 IMAGE-MGC_LOAD
  IMAGE:7193448 IMAGE-MGC_LOAD
  IMAGE:8365327 IMAGE-MGC_LOAD
InterPro COQ9 UniProtKB/Swiss-Prot
  COQ9_HTH UniProtKB/Swiss-Prot
  Ubiq_biosynth_COQ9 UniProtKB/Swiss-Prot
KEGG Report rno:498909 UniProtKB/Swiss-Prot
MGC_CLONE MGC:125120 IMAGE-MGC_LOAD
  MGC:156484 IMAGE-MGC_LOAD
  MGC:94856 IMAGE-MGC_LOAD
NCBI Gene 498909 ENTREZGENE
PANTHER PTHR21427 UniProtKB/Swiss-Prot
  UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam COQ9 UniProtKB/Swiss-Prot
  COQ9_N UniProtKB/Swiss-Prot
PhenoGen Coq9 PhenoGen
RatGTEx ENSRNOG00000016190 RatGTEx
UniProt A0A8L2UJQ7 ENTREZGENE, UniProtKB/TrEMBL
  A1L109 ENTREZGENE
  COQ9_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A1L109 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-11 Coq9  coenzyme Q9  Coq9  coenzyme Q9 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Coq9  coenzyme Q9 homolog (S. cerevisiae)  LOC498909  similar to RIKEN cDNA 2310005O14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC498909  similar to RIKEN cDNA 2310005O14      Symbol and Name status set to provisional 70820 PROVISIONAL