C19h16orf78 (similar to human chromosome 16 open reading frame 78) - Rat Genome Database

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Gene: C19h16orf78 (similar to human chromosome 16 open reading frame 78) Rattus norvegicus
Analyze
Symbol: C19h16orf78
Name: similar to human chromosome 16 open reading frame 78
RGD ID: 1585876
Description: Orthologous to human C16orf78 (chromosome 16 open reading frame 78); INTERACTS WITH bisphenol A; benzo[a]pyrene (ortholog); bis(2-ethylhexyl) phthalate (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hypothetical protein LOC680913; LOC680913; uncharacterized protein C16orf78 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81935,657,645 - 35,683,019 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1935,657,278 - 35,682,864 (-)EnsemblGRCr8
mRatBN7.21919,484,248 - 19,509,632 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1919,483,882 - 19,509,469 (-)EnsemblmRatBN7.2
Rnor_6.01920,483,348 - 20,509,072 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1920,483,361 - 20,508,711 (-)Ensemblrn6Rnor6.0
Rnor_5.01931,494,308 - 31,519,661 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41920,816,710 - 20,841,478 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1919,364,801 - 19,390,525 (-)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21630459  


Genomics

Comparative Map Data
C19h16orf78
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81935,657,645 - 35,683,019 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1935,657,278 - 35,682,864 (-)EnsemblGRCr8
mRatBN7.21919,484,248 - 19,509,632 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1919,483,882 - 19,509,469 (-)EnsemblmRatBN7.2
Rnor_6.01920,483,348 - 20,509,072 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1920,483,361 - 20,508,711 (-)Ensemblrn6Rnor6.0
Rnor_5.01931,494,308 - 31,519,661 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41920,816,710 - 20,841,478 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1919,364,801 - 19,390,525 (-)NCBICelera
Cytogenetic Map19p11NCBI
C16orf78
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381649,373,804 - 49,399,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1649,373,804 - 49,399,431 (+)Ensemblhg38GRCh38
GRCh371649,407,715 - 49,433,342 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361647,965,309 - 47,990,822 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1633,919,770 - 33,945,283 (+)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1635,297,431 - 35,322,944 (+)NCBIHuRef
CHM1_11650,814,732 - 50,840,245 (+)NCBICHM1_1
T2T-CHM13v2.01655,171,560 - 55,197,187 (+)NCBIT2T-CHM13v2.0
4933402J07Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39888,290,535 - 88,315,825 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl888,290,481 - 88,316,052 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38887,563,907 - 87,589,197 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl887,563,853 - 87,589,424 (+)Ensemblmm10GRCm38
MGSCv37890,087,806 - 90,113,096 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36890,454,012 - 90,479,302 (+)NCBIMGSCv36mm8
Celera891,829,032 - 91,854,280 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map842.21NCBI
CUNH16orf78
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554337,603,234 - 7,620,319 (+)NCBIChiLan1.0ChiLan1.0
C18H16orf78
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21858,828,598 - 58,862,989 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11664,733,929 - 64,767,922 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01629,634,536 - 29,660,125 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11648,522,313 - 48,547,900 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1648,522,313 - 48,547,900 (+)EnsemblpanPan2panpan1.1
C2H16orf78
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1265,866,069 - 65,880,700 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl265,859,569 - 65,880,672 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha262,443,308 - 62,457,713 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0266,416,892 - 66,431,320 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl266,412,367 - 66,431,296 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1263,240,320 - 63,254,721 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0264,260,125 - 64,274,753 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0265,148,584 - 65,163,031 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH16orf78
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934956,977,687 - 57,003,218 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364752,585,895 - 2,611,173 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C6H16orf78
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl635,393,669 - 35,409,872 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1635,394,618 - 35,409,614 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
C5H16orf78
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1535,165,260 - 35,189,510 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl535,165,542 - 35,189,373 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604741,313,770 - 41,338,122 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH16orf78
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247577,147,835 - 7,170,324 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247577,147,930 - 7,170,258 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in C19h16orf78
114 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:140
Count of miRNA genes:93
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000032408, ENSRNOT00000060742
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat

Markers in Region
D19Got134  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81935,680,794 - 35,680,935 (+)Marker Load Pipeline
mRatBN7.21919,507,399 - 19,507,540 (+)MAPPERmRatBN7.2
Rnor_6.01920,506,498 - 20,506,636NCBIRnor6.0
Rnor_5.01931,517,458 - 31,517,596UniSTSRnor5.0
RGSC_v3.41920,839,411 - 20,839,549UniSTSRGSC3.4
Celera1919,387,951 - 19,388,089UniSTS
Cytogenetic Map19p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 3 7 32 33 30 17 7 17 6 68 27 20 16 30 13

Sequence


Ensembl Acc Id: ENSRNOT00000032408   ⟹   ENSRNOP00000035956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1935,657,278 - 35,682,864 (-)Ensembl
mRatBN7.2 Ensembl1919,483,882 - 19,509,469 (-)Ensembl
Rnor_6.0 Ensembl1920,483,361 - 20,508,711 (-)Ensembl
RefSeq Acc Id: XM_006255322   ⟹   XP_006255384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,657,645 - 35,683,019 (-)NCBI
mRatBN7.21919,484,248 - 19,509,630 (-)NCBI
Rnor_6.01920,483,348 - 20,508,948 (-)NCBI
Rnor_5.01931,494,308 - 31,519,661 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039098307   ⟹   XP_038954235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,657,645 - 35,683,019 (-)NCBI
mRatBN7.21919,484,248 - 19,509,632 (-)NCBI
RefSeq Acc Id: XM_039098308   ⟹   XP_038954236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,657,645 - 35,683,018 (-)NCBI
mRatBN7.21919,484,248 - 19,509,629 (-)NCBI
RefSeq Acc Id: XM_063278851   ⟹   XP_063134921
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,677,645 - 35,683,018 (-)NCBI
Protein Sequences
Protein RefSeqs XP_006255384 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954235 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954236 (Get FASTA)   NCBI Sequence Viewer  
  XP_063134921 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000035956.4
RefSeq Acc Id: XP_006255384   ⟸   XM_006255322
- Peptide Label: isoform X1
- UniProtKB: D3ZYH9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035956   ⟸   ENSRNOT00000032408
RefSeq Acc Id: XP_038954235   ⟸   XM_039098307
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038954236   ⟸   XM_039098308
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063134921   ⟸   XM_063278851
- Peptide Label: isoform X4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZYH9-F1-model_v2 AlphaFold D3ZYH9 1-271 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700984
Promoter ID:EPDNEW_R11506
Type:multiple initiation site
Name:LOC680913_1
Description:hypothetical protein LOC680913
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01920,508,667 - 20,508,727EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1585876 AgrOrtholog
BioCyc Gene G2FUF-6264 BioCyc
Ensembl Genes ENSRNOG00000024182 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032408.6 UniProtKB/TrEMBL
InterPro DUF4638 UniProtKB/TrEMBL
NCBI Gene 680913 ENTREZGENE
PANTHER PTHR35679 UniProtKB/TrEMBL
  RIKEN CDNA 4933402J07 GENE UniProtKB/TrEMBL
Pfam DUF4638 UniProtKB/TrEMBL
PhenoGen C19h16orf78 PhenoGen
RatGTEx ENSRNOG00000024182 RatGTEx
UniProt D3ZYH9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C19h16orf78  similar to human chromosome 16 open reading frame 78  LOC680913  hypothetical protein LOC680913  Symbol and Name Changed 1299863 APPROVED
2008-01-09 LOC680913  hypothetical protein LOC680913  LOC683763  hypothetical protein LOC683763  Data merged from RGD:1583331 1643240 APPROVED
2006-11-19 LOC680913  hypothetical protein LOC680913      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683763  hypothetical protein LOC683763      Symbol and Name status set to provisional 70820 PROVISIONAL