Luzp4 (leucine zipper protein 4) - Rat Genome Database

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Gene: Luzp4 (leucine zipper protein 4) Rattus norvegicus
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Symbol: Luzp4
Name: leucine zipper protein 4
RGD ID: 1584898
Description: Orthologous to human LUZP4 (leucine zipper protein 4); INTERACTS WITH ammonium chloride; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: filaggrin; LIM domain-containing protein A; Ott; ovary testis transcribed
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X116,092,515 - 116,133,390 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX116,092,563 - 116,133,389 (+)EnsemblGRCr8
mRatBN7.2X111,280,490 - 111,321,363 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX111,280,549 - 111,321,359 (+)EnsemblmRatBN7.2
Rnor_6.0X118,725,749 - 118,766,413 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X118,868,434 - 118,908,710 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X30,226,835 - 30,252,051 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX110,595,944 - 110,621,388 (+)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:25662211  


Genomics

Comparative Map Data
Luzp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X116,092,515 - 116,133,390 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX116,092,563 - 116,133,389 (+)EnsemblGRCr8
mRatBN7.2X111,280,490 - 111,321,363 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX111,280,549 - 111,321,359 (+)EnsemblmRatBN7.2
Rnor_6.0X118,725,749 - 118,766,413 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X118,868,434 - 118,908,710 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X30,226,835 - 30,252,051 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX110,595,944 - 110,621,388 (+)NCBICelera
Cytogenetic MapXq34NCBI
LUZP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X115,289,715 - 115,307,563 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX115,289,715 - 115,307,563 (+)Ensemblhg38GRCh38
GRCh37X114,524,281 - 114,542,128 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X114,430,548 - 114,448,377 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X114,347,300 - 114,365,101NCBI
CeleraX114,959,452 - 114,977,280 (+)NCBICelera
Cytogenetic MapXq23NCBI
HuRefX104,109,766 - 104,127,338 (+)NCBIHuRef
CHM1_1X114,435,342 - 114,453,171 (+)NCBICHM1_1
T2T-CHM13v2.0X113,698,307 - 113,716,155 (+)NCBIT2T-CHM13v2.0
Ott
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X147,880,948 - 147,921,148 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX147,857,278 - 147,921,148 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X149,097,952 - 149,138,152 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX149,074,282 - 149,138,152 (+)Ensemblmm10GRCm38
MGSCv37X145,532,495 - 145,572,695 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X144,344,320 - 144,384,520 (+)NCBIMGSCv36mm8
CeleraX134,704,104 - 134,704,749 (+)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Luzp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955490448,290 - 490,242 (-)NCBIChiLan1.0ChiLan1.0
LUZP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X114,731,372 - 114,752,517 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X114,734,980 - 114,756,125 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X104,379,434 - 104,399,451 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X114,883,781 - 114,902,956 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX114,883,028 - 114,903,813 (+)EnsemblpanPan2panpan1.1
LUZP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X88,041,381 - 88,063,726 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX88,041,376 - 88,063,708 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX74,162,067 - 74,202,885 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X89,756,066 - 89,797,063 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX89,756,060 - 89,796,460 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X87,199,156 - 87,240,099 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X88,874,470 - 88,915,294 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X88,709,122 - 88,750,114 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Luzp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X87,054,684 - 87,069,432 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936499588,532 - 603,280 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LUZP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X94,631,490 - 94,647,712 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X109,199,862 - 109,229,986 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LUZP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X102,866,701 - 102,885,091 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606528,222,344 - 28,239,434 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Luzp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624940483,376 - 547,385 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Luzp4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X101,050,921 - 101,074,448 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Luzp4
89 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX92979612117740458Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X105468858125434318Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat


Expression

RNA-SEQ Expression

circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
sensory system
visual system
1 4 1 3 2 4 1 7 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000104511   ⟹   ENSRNOP00000088291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX111,280,549 - 111,321,359 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111862   ⟹   ENSRNOP00000092274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX111,280,549 - 111,321,359 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117574   ⟹   ENSRNOP00000094968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX116,092,563 - 116,133,389 (+)Ensembl
mRatBN7.2 EnsemblX111,280,549 - 111,321,359 (+)Ensembl
RefSeq Acc Id: NM_001408923   ⟹   NP_001395852
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X116,092,515 - 116,133,390 (+)NCBI
mRatBN7.2X111,280,490 - 111,321,363 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001395852 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA68173 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000094968
  ENSRNOP00000094968.1
Ensembl Acc Id: ENSRNOP00000094968   ⟸   ENSRNOT00000117574
Ensembl Acc Id: ENSRNOP00000092274   ⟸   ENSRNOT00000111862
Ensembl Acc Id: ENSRNOP00000088291   ⟸   ENSRNOT00000104511
RefSeq Acc Id: NP_001395852   ⟸   NM_001408923
- UniProtKB: A0A8I6AP28 (UniProtKB/TrEMBL),   A0A8I6A7S9 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584898 AgrOrtholog
BioCyc Gene G2FUF-1438 BioCyc
Ensembl Genes ENSRNOG00000069107 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000117574 ENTREZGENE
  ENSRNOT00000117574.2 UniProtKB/TrEMBL
InterPro Trans_Neuromod_Peptide-like UniProtKB/TrEMBL
NCBI Gene 367753 ENTREZGENE
PANTHER LEUCINE ZIPPER PROTEIN 4-RELATED UniProtKB/TrEMBL
  LEUCINE ZIPPER PROTEIN 4-RELATED UniProtKB/TrEMBL
PhenoGen Luzp4 PhenoGen
RatGTEx ENSRNOG00000069107 RatGTEx
UniProt A0A8I6A7S9 ENTREZGENE
  A0A8I6AP28 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-25 Luzp4  leucine zipper protein 4  Ott  ovary testis transcribed  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 Ott  ovary testis transcribed      Symbol and Name status set to provisional 70820 PROVISIONAL