Lhfpl7 (LHFPL tetraspan subfamily member 7) - Rat Genome Database

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Gene: Lhfpl7 (LHFPL tetraspan subfamily member 7) Rattus norvegicus
Analyze
Symbol: Lhfpl7
Name: LHFPL tetraspan subfamily member 7
RGD ID: 1584759
Description: Predicted to be active in membrane. Orthologous to human LHFPL7 (LHFPL tetraspan subfamily member 7); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hypothetical protein LOC679783; hypothetical protein LOC687903; LOC679783; Tmem211; transmembrane protein 211
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81249,053,607 - 49,057,890 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1249,053,740 - 49,057,890 (-)EnsemblGRCr8
mRatBN7.21243,393,166 - 43,397,472 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,391,632 - 43,401,320 (-)EnsemblmRatBN7.2
Rnor_6.01249,401,768 - 49,406,037 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1249,401,667 - 49,412,796 (-)Ensemblrn6Rnor6.0
Rnor_5.01251,176,003 - 51,180,329 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41244,402,030 - 44,406,180 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1244,989,759 - 44,994,028 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Lhfpl7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81249,053,607 - 49,057,890 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1249,053,740 - 49,057,890 (-)EnsemblGRCr8
mRatBN7.21243,393,166 - 43,397,472 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,391,632 - 43,401,320 (-)EnsemblmRatBN7.2
Rnor_6.01249,401,768 - 49,406,037 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1249,401,667 - 49,412,796 (-)Ensemblrn6Rnor6.0
Rnor_5.01251,176,003 - 51,180,329 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41244,402,030 - 44,406,180 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1244,989,759 - 44,994,028 (-)NCBICelera
Cytogenetic Map12q16NCBI
LHFPL7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,935,098 - 24,946,694 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,935,098 - 24,946,695 (-)Ensemblhg38GRCh38
GRCh372225,331,065 - 25,342,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,661,208 - 23,665,314 (-)NCBIBuild 36Build 36hg18NCBI36
Celera229,135,586 - 9,139,692 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef228,279,978 - 8,284,084 (-)NCBIHuRef
CHM1_12225,289,941 - 25,294,051 (-)NCBICHM1_1
T2T-CHM13v2.02225,396,656 - 25,408,280 (-)NCBIT2T-CHM13v2.0
Lhfpl7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395113,374,775 - 113,388,089 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5113,374,775 - 113,387,129 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385113,226,909 - 113,240,223 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5113,226,909 - 113,239,263 (+)Ensemblmm10GRCm38
MGSCv375113,655,929 - 113,668,283 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365113,467,212 - 113,479,566 (+)NCBIMGSCv36mm8
Celera5110,347,217 - 110,359,579 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.43NCBI
Lhfpl7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955455237,252 - 250,819 (+)Ensembl
ChiLan1.0NW_004955455237,462 - 251,622 (+)NCBIChiLan1.0ChiLan1.0
LHFPL7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22334,834,916 - 34,847,287 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12237,533,704 - 37,545,943 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0225,890,285 - 5,906,573 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12223,557,166 - 23,569,025 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2223,557,401 - 23,561,701 (-)EnsemblpanPan2panpan1.1
LHFPL7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12619,063,479 - 19,076,840 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2619,063,490 - 19,067,467 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2618,929,649 - 18,942,920 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02619,428,993 - 19,442,271 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2619,428,993 - 19,432,966 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12619,134,508 - 19,147,696 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02619,400,207 - 19,413,403 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02619,469,329 - 19,482,639 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lhfpl7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118115,720,864 - 115,724,495 (+)NCBIHiC_Itri_2
LHFPL7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1442,980,659 - 42,989,722 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11442,980,177 - 42,987,894 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21445,711,611 - 45,716,115 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LHFPL7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1198,031,900 - 8,043,244 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl198,032,037 - 8,036,169 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045118,222,893 - 118,227,473 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lhfpl7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247472,097,246 - 2,103,065 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Lhfpl7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11640,734,567 - 40,739,195 (-)NCBIRrattus_CSIRO_v1


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)124413955852308831Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
7 6 8 46 33 30 17 6 17 6 72 29 34 16 33 13 3 3

Sequence


Ensembl Acc Id: ENSRNOT00000076878   ⟹   ENSRNOP00000068428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1249,401,890 - 49,406,037 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092480   ⟹   ENSRNOP00000075893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1243,391,632 - 43,401,320 (-)Ensembl
Rnor_6.0 Ensembl1249,401,667 - 49,412,796 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000140874   ⟹   ENSRNOP00000104347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1249,053,740 - 49,057,890 (-)Ensembl
RefSeq Acc Id: XM_001054448   ⟹   XP_001054448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,053,607 - 49,057,890 (-)NCBI
mRatBN7.21243,393,166 - 43,397,472 (-)NCBI
Rnor_6.01249,401,768 - 49,406,037 (-)NCBI
Rnor_5.01251,176,003 - 51,180,329 (-)NCBI
RGSC_v3.41244,402,030 - 44,406,180 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_001054448 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000104347
  ENSRNOP00000104347.1
RefSeq Acc Id: XP_001054448   ⟸   XM_001054448
- UniProtKB: A0A0U1RS14 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075893   ⟸   ENSRNOT00000092480
Ensembl Acc Id: ENSRNOP00000068428   ⟸   ENSRNOT00000076878
Ensembl Acc Id: ENSRNOP00000104347   ⟸   ENSRNOT00000140874

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MK95-F1-model_v2 AlphaFold A0A096MK95 1-195 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584759 AgrOrtholog
BioCyc Gene G2FUF-18894 BioCyc
Ensembl Genes ENSRNOG00000051192 Ensembl
  ENSRNOG00000087492 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000140874 ENTREZGENE
  ENSRNOT00000140874.1 UniProtKB/TrEMBL
NCBI Gene 679783 ENTREZGENE
PhenoGen Lhfpl7 PhenoGen
RatGTEx ENSRNOG00000051192 RatGTEx
  ENSRNOG00000087492 RatGTEx
UniProt A0A0U1RS14 ENTREZGENE
  A0ABK0LUM7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-12-16 Lhfpl7  LHFPL tetraspan subfamily member 7  Tmem211  transmembrane protein 211  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Tmem211  transmembrane protein 211  LOC687903  hypothetical protein LOC687903  Data merged from RGD:1594945 1643240 APPROVED
2008-07-17 Tmem211  transmembrane protein 211  LOC679783  hypothetical protein LOC679783  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC687903  hypothetical protein LOC687903      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC679783  hypothetical protein LOC679783      Symbol and Name status set to provisional 70820 PROVISIONAL