Coxfa4 (cytochrome c oxidase associated subunit FA4) - Rat Genome Database

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Gene: Coxfa4 (cytochrome c oxidase associated subunit FA4) Rattus norvegicus
Analyze
Symbol: Coxfa4 (Ensembl: Ndufa4)
Name: cytochrome c oxidase associated subunit FA4 (Ensembl:NDUFA4, mitochondrial complex associated)
RGD ID: 1584719
Description: Part of respiratory chain complex I and respiratory chain complex IV. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 21. Orthologous to human NDUFA4 (NDUFA4 mitochondrial complex associated); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 17beta-estradiol (ortholog); 3-chloropropane-1,2-diol (ortholog); 4,4'-sulfonyldiphenol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cytochrome c oxidase subunit NDUFA4; LOC681024; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH:ubiquinone oxidoreductase subunit A4; Ndufa4; Ndufa4, mitochondrial complex associated; similar to NADH-ubiquinone oxidoreductase MLRQ subunit (Complex I-MLRQ) (CI-MLRQ)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Gluco61 Niddm71
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8440,968,391 - 40,975,559 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl440,968,391 - 40,975,559 (-)EnsemblGRCr8
mRatBN7.2440,002,216 - 40,009,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl440,002,216 - 40,023,920 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx444,975,238 - 44,982,402 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0440,901,442 - 40,908,606 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0439,304,957 - 39,312,121 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0438,233,680 - 38,240,848 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl438,233,680 - 38,240,848 (-)Ensemblrn6Rnor6.0
Rnor_5.0438,070,978 - 38,078,251 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4437,125,782 - 37,133,055 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera435,414,376 - 35,421,532 (-)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. A novel mutation in the NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4 (Ndufa4) gene links mitochondrial dysfunction to the development of diabetes in a rodent model. Yagil C, etal., Dis Model Mech. 2018 Nov 20;11(11). pii: dmm.036699. doi: 10.1242/dmm.036699.
Additional References at PubMed
PMID:12477932   PMID:12611891   PMID:12865426   PMID:14651853   PMID:16729965   PMID:18614015   PMID:20530722   PMID:22902835   PMID:23209302   PMID:23376485   PMID:30030519   PMID:31536960  
PMID:33994501   PMID:35352799  


Genomics

Comparative Map Data
Coxfa4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8440,968,391 - 40,975,559 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl440,968,391 - 40,975,559 (-)EnsemblGRCr8
mRatBN7.2440,002,216 - 40,009,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl440,002,216 - 40,023,920 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx444,975,238 - 44,982,402 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0440,901,442 - 40,908,606 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0439,304,957 - 39,312,121 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0438,233,680 - 38,240,848 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl438,233,680 - 38,240,848 (-)Ensemblrn6Rnor6.0
Rnor_5.0438,070,978 - 38,078,251 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4437,125,782 - 37,133,055 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera435,414,376 - 35,421,532 (-)NCBICelera
Cytogenetic Map4q21NCBI
COXFA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38710,931,943 - 10,940,153 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl710,931,943 - 10,940,531 (-)Ensemblhg38GRCh38
GRCh37710,971,570 - 10,979,780 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36710,939,340 - 10,946,338 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34710,746,054 - 10,753,053NCBI
Celera710,947,593 - 10,954,592 (-)NCBICelera
Cytogenetic Map7p21.3NCBI
HuRef710,829,724 - 10,838,039 (-)NCBIHuRef
CHM1_1710,972,141 - 10,980,374 (-)NCBICHM1_1
T2T-CHM13v2.0711,062,535 - 11,070,743 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2711,025,124 - 11,033,358 (-)NCBI
Coxfa4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39611,900,371 - 11,907,449 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl611,900,291 - 11,907,496 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38611,900,372 - 11,907,450 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl611,900,292 - 11,907,497 (-)Ensemblmm10GRCm38
MGSCv37611,850,373 - 11,857,446 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36611,850,373 - 11,857,446 (-)NCBIMGSCv36mm8
Celera611,992,912 - 11,999,985 (-)NCBICelera
Cytogenetic Map6A1NCBI
cM Map65.01NCBI
Coxfa4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543217,502,272 - 17,509,517 (-)Ensembl
ChiLan1.0NW_00495543217,502,272 - 17,509,517 (-)NCBIChiLan1.0ChiLan1.0
COXFA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2615,760,949 - 15,767,672 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1764,085,666 - 64,092,390 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0711,585,054 - 11,591,775 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1710,932,727 - 10,939,949 (-)NCBIPanPan1.1PanPan1.1panPan2
COXFA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11425,887,204 - 25,893,746 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1425,468,815 - 25,475,355 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01425,696,535 - 25,703,079 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11425,864,709 - 25,871,252 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01425,594,037 - 25,600,585 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01425,847,856 - 25,854,404 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Coxfa4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511839,433,348 - 39,440,232 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936761554,028 - 560,901 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936761554,025 - 560,913 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COXFA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl980,636,929 - 80,644,315 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1980,637,005 - 80,644,067 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2988,555,979 - 88,563,046 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COXFA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12147,245,396 - 47,252,145 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2147,245,170 - 47,252,730 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604257,188,514 - 57,195,774 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Coxfa4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248278,366,027 - 8,375,881 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248278,366,597 - 8,373,881 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Coxfa4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16126,886,617 - 126,893,618 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Coxfa4
43 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:252
Count of miRNA genes:166
Interacting mature miRNAs:190
Transcripts:ENSRNOT00000007567
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)41308014658080146Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41564430960644309Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41103870656038706Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
8655949Rf62Renal function QTL 6222blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)43539660045429897Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)44049044275726188Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41103870656038706Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4589457557613242Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41103870656038706Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41890069763900697Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43726957782269577Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4145429897Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41103870656038706Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)44047145375939996Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42228845363245191Rat
2290374Gluco32Glucose level QTL 326.27blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43814419445429897Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)41890069763900697Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41103870656038706Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4588999950889999Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41891315163913151Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42786220462997402Rat
4889511Gluco61Glucose level QTL 614.70.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43814419441835141Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42192515166925151Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41103870656038706Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43353881653719714Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42228845345429897Rat

Markers in Region
RH127505  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2181,120,397 - 1,120,573 (+)MAPPERmRatBN7.2
Rnor_6.0181,279,266 - 1,279,441NCBIRnor6.0
Rnor_5.0181,321,700 - 1,321,875UniSTSRnor5.0
RGSC_v3.4181,396,306 - 1,396,481UniSTSRGSC3.4
Celera181,006,194 - 1,006,369UniSTS
RH 3.4 Map1832.2UniSTS
Cytogenetic Map18p13UniSTS
Cytogenetic Map4q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007567   ⟹   ENSRNOP00000007567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl440,968,391 - 40,974,593 (-)Ensembl
mRatBN7.2 Ensembl440,002,216 - 40,008,418 (-)Ensembl
Rnor_6.0 Ensembl438,233,680 - 38,240,848 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108269   ⟹   ENSRNOP00000093714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl440,005,645 - 40,023,920 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112879   ⟹   ENSRNOP00000096418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl440,968,391 - 40,975,559 (-)Ensembl
mRatBN7.2 Ensembl440,002,392 - 40,023,920 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000150054   ⟹   ENSRNOP00000102343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl440,973,428 - 40,975,559 (-)Ensembl
RefSeq Acc Id: NM_001127684   ⟹   NP_001121156
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8440,968,391 - 40,975,559 (-)NCBI
mRatBN7.2440,002,216 - 40,009,384 (-)NCBI
Rnor_6.0438,233,680 - 38,240,848 (-)NCBI
Rnor_5.0438,070,978 - 38,078,251 (-)NCBI
RGSC_v3.4437,125,782 - 37,133,055 (-)RGD
Celera435,414,376 - 35,421,532 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001121156 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI67115 (Get FASTA)   NCBI Sequence Viewer  
  EDM15076 (Get FASTA)   NCBI Sequence Viewer  
  EDM15077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007567.4
  ENSRNOP00000096418
  ENSRNOP00000096418.1
  ENSRNOP00000102343.1
RefSeq Acc Id: NP_001121156   ⟸   NM_001127684
- UniProtKB: B2RZD6 (UniProtKB/TrEMBL),   A6IDY9 (UniProtKB/TrEMBL),   F7FN80 (UniProtKB/TrEMBL),   A0A8I6AQR1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007567   ⟸   ENSRNOT00000007567
Ensembl Acc Id: ENSRNOP00000093714   ⟸   ENSRNOT00000108269
Ensembl Acc Id: ENSRNOP00000096418   ⟸   ENSRNOT00000112879
Ensembl Acc Id: ENSRNOP00000102343   ⟸   ENSRNOT00000150054

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RZD6-F1-model_v2 AlphaFold B2RZD6 1-82 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692878
Promoter ID:EPDNEW_R3403
Type:initiation region
Name:Ndufa4_1
Description:NDUFA4, mitochondrial complex associated
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0438,240,814 - 38,240,874EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584719 AgrOrtholog
BioCyc Gene G2FUF-45634 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000005512 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007567.6 UniProtKB/TrEMBL
  ENSRNOT00000112879 ENTREZGENE
  ENSRNOT00000112879.2 UniProtKB/TrEMBL
  ENSRNOT00000150054.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6922256 IMAGE-MGC_LOAD
InterPro B12D UniProtKB/TrEMBL
KEGG Report rno:681024 UniProtKB/TrEMBL
MGC_CLONE MGC:189583 IMAGE-MGC_LOAD
NCBI Gene 681024 ENTREZGENE
PANTHER CYTOCHROME C OXIDASE SUBUNIT NDUFA4 UniProtKB/TrEMBL
  PTHR14256 UniProtKB/TrEMBL
Pfam B12D UniProtKB/TrEMBL
PhenoGen Coxfa4 PhenoGen
RatGTEx ENSRNOG00000005512 RatGTEx
UniProt A0A8I6AQR1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LHD9_RAT UniProtKB/TrEMBL
  A6IDY9 ENTREZGENE, UniProtKB/TrEMBL
  B2RZD6 ENTREZGENE
  F7FN80 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B2RZD6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-17 Coxfa4  cytochrome c oxidase associated subunit FA4  Ndufa4  Ndufa4, mitochondrial complex associated  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-04-28 Ndufa4  Ndufa4, mitochondrial complex associated  Ndufa4  NDUFA4, mitochondrial complex associated  Name changed 629549 APPROVED
2017-03-29 Ndufa4  NDUFA4, mitochondrial complex associated  Ndufa4  NADH:ubiquinone oxidoreductase subunit A4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-17 Ndufa4  NADH:ubiquinone oxidoreductase subunit A4  Ndufa4  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Ndufa4  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4  LOC681024  similar to NADH-ubiquinone oxidoreductase MLRQ subunit (Complex I-MLRQ) (CI-MLRQ)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC681024  similar to NADH-ubiquinone oxidoreductase MLRQ subunit (Complex I-MLRQ) (CI-MLRQ)  LOC679503  similar to NADH-ubiquinone oxidoreductase MLRQ subunit (Complex I-MLRQ) (CI-MLRQ)  Data merged from RGD:1587180 1643240 APPROVED
2006-11-19 LOC681024  similar to NADH-ubiquinone oxidoreductase MLRQ subunit (Complex I-MLRQ) (CI-MLRQ)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC679503  similar to NADH-ubiquinone oxidoreductase MLRQ subunit (Complex I-MLRQ) (CI-MLRQ)      Symbol and Name status set to provisional 70820 PROVISIONAL