Cxhxorf66 (similar to human chromosome X open reading frame 66) - Rat Genome Database

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Pathways
Gene: Cxhxorf66 (similar to human chromosome X open reading frame 66) Rattus norvegicus
Analyze
Symbol: Cxhxorf66
Name: similar to human chromosome X open reading frame 66
RGD ID: 1584124
Description: Predicted to be located in membrane. Orthologous to human CXorf66 (chromosome X open reading frame 66); INTERACTS WITH bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC688842; LOC688842; uncharacterized protein CXorf66 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X143,815,665 - 143,855,883 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX143,815,342 - 143,855,932 (-)EnsemblGRCr8
mRatBN7.2X138,779,374 - 138,819,595 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX138,779,382 - 138,785,707 (-)EnsemblmRatBN7.2
Rnor_6.0X143,554,334 - 143,596,247 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX143,554,441 - 143,558,521 (-)Ensemblrn6Rnor6.0
Rnor_5.0X143,582,426 - 143,623,550 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X145,966,542 - 145,970,640 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX134,850,165 - 134,890,849 (-)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Cxhxorf66
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X143,815,665 - 143,855,883 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX143,815,342 - 143,855,932 (-)EnsemblGRCr8
mRatBN7.2X138,779,374 - 138,819,595 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX138,779,382 - 138,785,707 (-)EnsemblmRatBN7.2
Rnor_6.0X143,554,334 - 143,596,247 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX143,554,441 - 143,558,521 (-)Ensemblrn6Rnor6.0
Rnor_5.0X143,582,426 - 143,623,550 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X145,966,542 - 145,970,640 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX134,850,165 - 134,890,849 (-)NCBICelera
Cytogenetic MapXq36NCBI
CXorf66
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X139,955,728 - 139,965,521 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX139,955,728 - 139,965,521 (-)Ensemblhg38GRCh38
GRCh37X139,037,887 - 139,047,680 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X138,865,550 - 138,875,345 (-)NCBIBuild 36Build 36hg18NCBI36
CeleraX139,405,526 - 139,415,319 (-)NCBICelera
Cytogenetic MapXq27.1NCBI
HuRefX128,305,293 - 128,306,307 (-)NCBIHuRef
CHM1_1X138,948,920 - 138,958,713 (-)NCBICHM1_1
T2T-CHM13v2.0X138,267,667 - 138,277,460 (-)NCBIT2T-CHM13v2.0
Gm7073
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X59,481,236 - 59,502,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX59,481,241 - 59,502,437 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X60,436,047 - 60,456,195 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX60,436,052 - 60,539,249 (-)Ensemblmm10GRCm38
MGSCv37X57,689,227 - 57,709,370 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X57,689,227 - 57,709,370 (-)NCBIMGSCv36mm8
CeleraX46,876,077 - 46,896,791 (-)NCBICelera
Cytogenetic MapXA6NCBI
cM MapX33.5NCBI
CUNHXorf66
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554895,318,531 - 5,327,883 (+)NCBIChiLan1.0ChiLan1.0
CXHXorf66
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X139,404,496 - 139,415,405 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X139,408,098 - 139,419,007 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X129,106,870 - 129,116,750 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X139,356,755 - 139,366,559 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX139,356,748 - 139,366,612 (-)EnsemblpanPan2panpan1.1
CXHXorf66
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X109,898,857 - 109,902,202 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX109,899,034 - 109,902,143 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX95,726,035 - 95,729,379 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X111,887,012 - 111,890,356 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX111,887,152 - 111,890,297 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X109,019,147 - 109,022,491 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X111,203,804 - 111,207,149 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X110,883,266 - 110,886,610 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CXHXorf66
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X107,946,213 - 107,950,539 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365137,664,110 - 7,668,227 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXHXorf66
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X114,596,809 - 114,602,521 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X130,868,310 - 130,872,289 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CXHXorf66
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X115,037,556 - 115,047,635 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX115,037,727 - 115,047,390 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606552,772,529 - 52,782,385 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNHXorf66
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248086,752,961 - 6,756,556 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
CXHXorf66
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X119,484,173 - 119,497,007 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cxhxorf66
92 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:19
Count of miRNA genes:18
Interacting mature miRNAs:19
Transcripts:ENSRNOT00000056598
Prediction methods:Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat


Expression

RNA-SEQ Expression

appendage
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
1 4 1 2 1 1 1 3 1 4 19 1

Sequence


Ensembl Acc Id: ENSRNOT00000056598   ⟹   ENSRNOP00000053437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX143,815,342 - 143,855,932 (-)Ensembl
mRatBN7.2 EnsemblX138,779,382 - 138,785,707 (-)Ensembl
Rnor_6.0 EnsemblX143,554,441 - 143,558,521 (-)Ensembl
RefSeq Acc Id: XM_006257600   ⟹   XP_006257662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X143,815,665 - 143,822,022 (-)NCBI
mRatBN7.2X138,779,374 - 138,785,727 (-)NCBI
Rnor_6.0X143,554,334 - 143,560,954 (-)NCBI
Rnor_5.0X143,582,426 - 143,623,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257601   ⟹   XP_006257663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X143,815,665 - 143,822,022 (-)NCBI
mRatBN7.2X138,779,374 - 138,785,727 (-)NCBI
Rnor_6.0X143,554,334 - 143,560,954 (-)NCBI
Rnor_5.0X143,582,426 - 143,623,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257602   ⟹   XP_006257664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X143,815,665 - 143,855,883 (-)NCBI
mRatBN7.2X138,779,374 - 138,819,595 (-)NCBI
Rnor_6.0X143,554,334 - 143,596,247 (-)NCBI
Rnor_5.0X143,582,426 - 143,623,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257603   ⟹   XP_006257665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X143,815,665 - 143,855,883 (-)NCBI
mRatBN7.2X138,779,374 - 138,819,595 (-)NCBI
Rnor_6.0X143,554,334 - 143,596,247 (-)NCBI
Rnor_5.0X143,582,426 - 143,623,550 (-)NCBI
Sequence:
RefSeq Acc Id: XP_006257665   ⟸   XM_006257603
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006257664   ⟸   XM_006257602
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006257663   ⟸   XM_006257601
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006257662   ⟸   XM_006257600
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000053437   ⟸   ENSRNOT00000056598

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLZ3-F1-model_v2 AlphaFold D3ZLZ3 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584124 AgrOrtholog
BioCyc Gene G2FUF-872 BioCyc
Ensembl Genes ENSRNOG00000037399 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056598.5 UniProtKB/TrEMBL
InterPro CXorf66 UniProtKB/TrEMBL
KEGG Report rno:688842 UniProtKB/TrEMBL
NCBI Gene 688842 ENTREZGENE
PANTHER GENE 7073-RELATED UniProtKB/TrEMBL
  PTHR37340 UniProtKB/TrEMBL
PhenoGen Cxhxorf66 PhenoGen
RatGTEx ENSRNOG00000037399 RatGTEx
UniProt D3ZLZ3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-01-03 Cxhxorf66  similar to human chromosome X open reading frame 66  LOC688842  hypothetical protein LOC688842  Name and Symbol changed 629549 APPROVED
2008-01-09 LOC688842  hypothetical protein LOC688842  LOC679106  hypothetical protein LOC679106  Data merged from RGD:1591886 1643240 APPROVED
2006-11-20 LOC679106  hypothetical protein LOC679106      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC688842  hypothetical protein LOC688842      Symbol and Name status set to provisional 70820 PROVISIONAL