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Gene: Hfm1 (helicase for meiosis 1) Rattus norvegicus

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Symbol:

Hfm1

Name:

helicase for meiosis 1

RGD ID:

1584010

Description:

Predicted to enable DNA helicase activity. Predicted to be involved in resolution of meiotic recombination intermediates. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 9. Orthologous to human HFM1 (helicase for meiosis 1); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; N,N-diethyl-m-toluamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

HFM1, ATP-dependent DNA helicase homolog; HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae); LOC501885; LOC690161; probable ATP-dependent DNA helicase HFM1; similar to HFM1, ATP-dependent DNA helicase homolog; similar to novel protein (FLJ36760)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HFM1 (helicase for meiosis 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Hfm1 (HFM1, ATP-dependent DNA helicase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hfm1 (helicase for meiosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HFM1 (helicase for meiosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HFM1 (helicase for meiosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hfm1 (helicase for meiosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HFM1 (helicase for meiosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HFM1 (helicase for meiosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hfm1 (helicase for meiosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Hfm1 (helicase for meiosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	HFM1 (helicase for meiosis 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Hfm1 (HFM1, ATP-dependent DNA helicase homolog)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	hfm1 (helicase for meiosis 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	hfm1 (helicase for meiosis 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	HFM1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	HFM1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	hfm1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	hfm1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	3,002,103 - 3,108,567 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	3,001,906 - 3,084,401 (+)	Ensembl				GRCr8
mRatBN7.2	14	2,857,251 - 2,943,766 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	2,856,599 - 2,939,238 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	2,738,710 - 2,817,281 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	4,040,205 - 4,118,784 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	2,740,225 - 2,818,798 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	3,879,172 - 3,961,139 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	3,882,398 - 3,960,909 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	3,876,228 - 3,958,179 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	3,477,851 - 3,556,999 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	2,875,579 - 2,955,062 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

azoospermia (ISO)

hereditary breast ovarian cancer syndrome (ISO)

primary ovarian insufficiency 16 (ISO)

primary ovarian insufficiency 9 (ISO)

spermatogenic failure 4 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol A diglycidyl ether (ISO)

bisphenol AF (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

dorsomorphin (ISO)

fulvestrant (ISO)

iron dichloride (ISO)

lead(0) (ISO)

methotrexate (ISO)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorooctanoic acid (ISO)

permethrin (EXP)

SB 431542 (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

meiotic cell cycle (IEA)

resolution of meiotic recombination intermediates (IBA,ISO)

Cellular Component

Golgi apparatus (ISO)

nucleus (IBA)

Molecular Function

3'-5' DNA helicase activity (IEA)

ATP binding (IEA)

DNA helicase activity (IBA)

helicase activity (IEA)

hydrolase activity (IEA)

isomerase activity (IEA)

nucleic acid binding (IEA)

nucleotide binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23555294

Genomics

Comparative Map Data

Hfm1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	3,002,103 - 3,108,567 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	3,001,906 - 3,084,401 (+)	Ensembl				GRCr8
mRatBN7.2	14	2,857,251 - 2,943,766 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	2,856,599 - 2,939,238 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	2,738,710 - 2,817,281 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	4,040,205 - 4,118,784 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	2,740,225 - 2,818,798 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	3,879,172 - 3,961,139 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	3,882,398 - 3,960,909 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	3,876,228 - 3,958,179 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	3,477,851 - 3,556,999 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	2,875,579 - 2,955,062 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

HFM1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	91,260,766 - 91,408,007 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	91,260,766 - 91,404,856 (-)	Ensembl			hg38	GRCh38
GRCh37	1	91,726,323 - 91,870,394 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	91,498,911 - 91,643,014 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	89,974,186 - 90,118,312 (-)	NCBI		Celera
Cytogenetic Map	1	p22.2	NCBI
HuRef	1	89,845,547 - 89,989,669 (-)	NCBI		HuRef
CHM1_1	1	91,841,173 - 91,985,260 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	91,105,413 - 91,252,636 (-)	NCBI		T2T-CHM13v2.0

Hfm1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	106,988,059 - 107,074,427 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	106,988,058 - 107,074,187 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	106,840,193 - 106,926,712 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	106,840,192 - 106,926,321 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	107,269,216 - 107,354,909 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	107,142,191 - 107,166,192 (-)	NCBI		MGSCv36	mm8
Celera	5	103,958,350 - 104,043,607 (-)	NCBI		Celera
Cytogenetic Map	5	E5	NCBI
cM Map	5	51.43	NCBI

Hfm1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	2,993,682 - 3,089,024 (+)	Ensembl
ChiLan1.0	NW_004955423	2,993,723 - 3,088,391 (+)	NCBI	ChiLan1.0	ChiLan1.0

HFM1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	135,625,418 - 135,762,746 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	134,782,877 - 134,917,758 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	93,923,279 - 94,058,194 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	92,669,768 - 92,802,528 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	92,669,768 - 92,802,528 (-)	Ensembl			panPan2	panpan1.1

HFM1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	57,403,006 - 57,541,616 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	57,403,471 - 57,534,615 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	60,107,979 - 60,257,033 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	57,785,587 - 57,935,671 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	57,819,298 - 57,918,158 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	57,461,604 - 57,610,980 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	57,436,714 - 57,576,808 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	57,900,647 - 58,050,087 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Hfm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	101,259,251 - 101,341,922 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936537	7,606,025 - 7,741,219 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HFM1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	125,522,334 - 125,606,882 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	125,522,300 - 125,614,296 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	137,103,085 - 137,187,996 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HFM1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	41,837,289 - 41,957,302 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666194	55,576 - 137,417 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hfm1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624742	6,394,790 - 6,513,601 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Hfm1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	16,607,398 - 16,689,392 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Hfm1
580 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	82
Count of miRNA genes:	69
Interacting mature miRNAs:	71
Transcripts:	ENSRNOT00000033794
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411573	Bw139	Body weight QTL 139	4.7	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	14	1	40068101	Rat
9589814	Gluco67	Glucose level QTL 67	4.54	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	40068101	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41415516	Rat
71115	Niddm15	Non-insulin dependent diabetes mellitus QTL 15	4.8		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	11334906	Rat
71117	Niddm17	Non-insulin dependent diabetes mellitus QTL 17	2.35		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	17877928	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1	31893212	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	4	47	131	52	51	23	33	23	6	201	105	9	109	60	78	28	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001412564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599385	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092478	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033794 ⟹ ENSRNOP00000034409

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	3,001,906 - 3,084,218 (+)	Ensembl
mRatBN7.2 Ensembl	14	2,856,599 - 2,939,238 (+)	Ensembl
Rnor_6.0 Ensembl	14	3,882,398 - 3,960,909 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113420 ⟹ ENSRNOP00000083280

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	3,005,109 - 3,084,401 (+)	Ensembl
mRatBN7.2 Ensembl	14	2,857,161 - 2,884,348 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000143122 ⟹ ENSRNOP00000103638

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	3,005,109 - 3,084,401 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000151673 ⟹ ENSRNOP00000103232

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	3,001,909 - 3,084,213 (+)	Ensembl

RefSeq Acc Id:

NM_001412564 ⟹ NP_001399493

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	3,002,591 - 3,084,401 (+)	NCBI
mRatBN7.2	14	2,857,715 - 2,939,525 (+)	NCBI

RefSeq Acc Id:

XM_008769948 ⟹ XP_008768170

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	3,002,103 - 3,108,567 (+)	NCBI
mRatBN7.2	14	2,857,251 - 2,943,766 (+)	NCBI
Rnor_6.0	14	3,879,690 - 3,961,139 (+)	NCBI

Sequence:

show sequence

TCCCTCGCGCTCCTTTGGGTGCGTGGTCCCGCAGGGTCTTCACGGAGGAAAGGTTTCTGTCTAG
TCAGTTATGCGTGAACGTCTGCGCTTCTGAAATAAGTATTCATTGTTTGTTTGCAACAGGGTCC
GGCTCTGTAGACCAGGCTATCCCTGCCTGGCTTCCGTCTTCCACCTCTCAAGTGTAGGGATTAC
TGTTGGGAGCCACTGGCGTCTGACTAAATTTCAGACAAAGTCTGTTTTTCAGCAATGCTGGAAT
CAAACGATTGCATTTTATCCATGGATTCTTTGTTTTTCAGTAGCCCAGGTGAAACTGAAAGCTT
TCCAGTTGAGGAAAAATCACTGGATTGGTTTCTCCCTCCAGCTCCACTGATCTCAGAAATTCCA
GATATTCAAGAGTTAGAGGAAGAAATTGAAAATTATAAGCTATTAGGAGAAAGAAAGATGCCCA
ATATATTAACATCAAACTTGAAGATCATTAATGAAGACACAAATTGTATTTCACCAACACAGAA
ATTCCATTTTCCCTATAACATACATGAACAGGATTACCTAAATTTAGGAGGATTAAATAACAAT
GACATGTCACATACAGCTGGCAAGCTAGTGTACGGTTCTTCTCAAAAATATAAAAACCACATGG
GGGATGAGAGTCCACCGACAAAGAGTGGTCCTGGTGATGCAAAGCTGCATACTGCTGCTGAGGA
CAGAGAGGGCACATCAGCACTCAAAACCAGATTATCTAGAACATGTGGCAGTGTGCAGGAATGT
GACTATGCTAATGGAAATTTAAGCTTGAATTCTCATATTAGCCCAGCGAGACTCACCCAAACAA
AAGTAAGCAAAGAGAAACCATGGAACTGTAGCAATAGAAAACAGAAACTGCAGTATTCTACAGA
CAAATCCAAAGCAAACGATGCTTTTTCTGCTTCTGGAATTGAAAAAGACATATTCGAAGCACCA
TCGTTTTCTGCTGCATCTCAGCCTCGTGACATTCAAGGCATAACCTCAAATGGCTTAGGTTCGT
TGAAGGCTGTCACAGAAATCCCTGCAAAATTTAGAAGTGTATTCAAAGAATTCCCTTACTTCAA
CTATATACAGTCCAAAGCCTTTGATGATCTTCTTTACACAGATCGGAATTTTGTGATTTGTGCC
CCCACTGGTTCTGGGAAAACTGTGGTGTTTGAGCTAGCAATAACAAGATTGTTAATGGAAGCAC
CATTGCCGTGGCTGAACATGAAAGTTGTTTACATGGCACCAATAAAAGCCCTTTGTAGTCAGCG
GTTTGATGACTGGAAAGAAAAATTTGGACCGATAGGCTTGACCTGTAAAGAACTTACTGGAGAT
ACAGTAATGGATGACCTGTTTGAGATTCAGCATGCCAATATAATTATGACAACTCCAGAGAAGT
GGGACAGTATGACTAGGAAGTGGAGAGACAACTCCTTCATCCAACTGGTTCGCCTGTTTCTCAT
TGATGAGGTGCATGTTATTAAAGATGAAAACCGTGGTCCAACTCTTGAGGTTGTAGTAAGCAGA
ATGAAAACTGTCCAGTCTTTATCTAAGACCTTAGAAAACGCCAGCCCTGCTCCAGTGAGGTTTG
TAGCTGTATCAGCAACAATTCCCAATGCTGAGGATATCGCAGAATGGCTTTCAGATGGGGAGAG
ACCTGCTGTGTGTCTGAAAATGGATGAGAGCCACAGACCTGTGAAACTTCAGAAAGTGGTCCTG
GGTTTCCCCAGTAGTAGTAACCAAACTGAATTCAAGTTTGATTTAGCCCTCAACTATAAAGTGT
ACAGTGTTATACGAACGTACTCCGATCAGAAGCCCACACTCGTGTTTTGTGCAACGAGGAAAGG
TGTGCAGCAGGCTGCTTCTGTTCTTGTGAAGGACGCTAAGTTTATCATCACCGTGGAGCAGAAA
CTACGGTTGCAGAAGTCTGCATATTCTATAAGGGATTCAAAGCTAAAAGATACCTTGGTGTACG
GTGTTGGTTACCATCATGCTGGAATGGAGCTGTCAGATAGAAAATTGGTTGAAGAGTTGTTTAC
TTCTGGAGATCTACCAGTTCTTTTTACTACAAGTACTCTAGCTATGGGAGTGAACTTGCCGGCT
CACCTGGTCGTTATAAAGTCCACCATGCACTACACTGGAGGTGCCTTTGAAGAGTACAGCGAGA
CAGACATCCTGCAGATGATTGGAAGAGCTGGCAGGCCCCAGTTTGACACCACAGCTACTGCAGT
TATTATGACCCGACTAAGTACAAGAGAGAAGTACGTTCAGATGCTAGCTTGTAATGACACTGTG
GAAAGCAGTTTGCACAGACATCTTATTGAGCACCTGAACGCAGAGATAGTGCTGCACACCATCA
CAGATGTGAGCATCGCCCTGGACTGGATCCGGTCCACACTGCTGTATATCAGAGCTCTGAAAAA
CCCATCTCACTATGGTTTTATATCTGGATTGAACAAAGATGGAATTGAAGCAAAATTACAAGAG
TTATGTTTGAAGAATCTGAAAGATTTATCATCGCTAGACCTAATAAAGATGGATGAAGACCTTA
ATTTCAGATCAACAGAGGCAGGAAGACTAATGGCATGGTATTATATTACATTTGAGACAGTGAA
GAAATTTTGTGCAATCAGTGGAAAAGAAACTTTATCAGATTTGATTTCAATGATATCCAGCTGC
AGTGAGTTTCTAGATGTGCAGCTGAGGATAAGCGAAAAGAGAACACTGAACACACTAAACAAAG
ACCCAAACCGGATAACCATCAGATTTCCAATGGAGGGGAGAATTAAAACCAGAGAGATGAAAGT
AAACTGTCTTATTCAGGCTCAGCTAGGATGCATCCCTATACAAGATTTTGCTTTGACACAAGAT
ACCTCGAAGATTTTCAGAAATGGCTCACGAATTGCAAAATGGTTGTCAGATTTTGTGACTGCTC
AGGAACAGAAGTTTGCTGTGCTTTTAAACAGTGTGATTTTAGCTAAATGTTTTAAGTGTAAACT
CTGGGAAAACTCTCAACATGTTTCAAAACAGCTGGATAAAATTGGCATATCATTGTCAAATACC
ATGGTAAATGCAGGCTTGACGTCTTTTAAAAAAATAGAAGAAGCAAATGCGAGAGAACTTGAAC
TGATTTTAAATAGACACCCGCCATTCGGGACCCAGATAAAGGAAGCTGTGATGTATCTGCCAAA
GTATGAACTTGAGGCAGAGCAGATTGCAAGATATAGTGATACCAAGGCAGAAATACTGGTGACC
ATTATATTAAGAAACTTTGAGCAGCTGCAGACCAAAAGAACAGCGCCAGACTTTCACTATGCCA
CCTTAATCATAGGTGATGCAGATAACCAAGTCGTTTGTAAGCACAAAATTATGGATTCTGTCTT
GTTAAAAAGTGGAAATTGGGTTAAAAAAATTGATGTGAAGAGAGCTCTTATATCAGAAGATCTC
AGCATAAATCTAATTAGCTCTGATTATGTTGGTCTTGATATTCACCAGAAATTTACAGTCTTTT
ATTTAGGACCCAGGAAGTTTGTAAATCAAACAGTTACGGAAAGAAGCTCAGGAACAGGTCTTTC
TCATTCCGAATGCTCAGACAGAGCTACTGCAGCAGGATCCAGTAAAAGAACGGCTACCTGCAGA
AACCCTGGGAACCGAGAATGCCATCATCACTGTAAAAATAAGCACATATGTGGGCATGACTGCT
GTAAAATTGGAGTTGCACAAAAGCCAGAAGCTAAAGTGTCAGCAGTGTCCTCATATCTGTCTGA
CCTAAAAAGCAGAGATGCTGTTTCTTCTTTTCCCCCAGCTAAGCGACTCAAGATACAGATGAAC
AAATCTCAAAATGTGGACCTTAAAGAATTTGGTTTTGTTCCAAGGCCTTCCCTTTCCAGTATAG
CAAGGTCAGAATATTTAAACATCCATAAATTGCCAATATTAGAACAGAGGACTCAGCATGAGAT
CTATGGCGAAGTTGAAGAGGGAGCGTCTGAATGCCGAGACGAAGCTTCAAACAAAAGGACCCCA
GTGATGCTCAGCAGACATGCTAACACACCTGGAAACCACGGTGTCGCAGTTGCAGAGAAGAGCA
AGTCTTCAGACGGCCCACATGTGAACTCAGAGCTGGGAGATGAAGTTTGGGATGACTTTGATGA
TGAAAGCTTAATAGAAGTTATGAGCTTTTCAGCTGACGCCGAGGAGATGGCTGTGTCAGGGTTT
GGAGACACTCGTGATTCAAGTCTAGGCAGAAGTAAGCTACACTTCGGAAGATCAAGCAGCAGGT
TCCAAAGAGACATCTCAAACAGTTTTGTTTCATCACCCGAGAAGCCAGATGTTTGTTTGTCAGA
TTGTTCCGTGTCTAATTTCGGGCTGTCCTCTGTGGCAGAGTTCCCTCAACAAGCTGGAAATGCA
AGTCTTGTCAATTTACAAGAGAGAAAACAGCTGACCCTCTCACCAGTGATTGAGAGGATGTGCT
TTACCCACTCTGAGAAAATACCACAGTCTCCCAGTTTTAAGGAAGTGGATATTTTTATTGGAAA
CAGTGACTCTAAAAAGGAAATTGATCTTAGTAAGTATTATCCTGATGATGCAGCCGAGGAAATG
AAGGCCCTTCTGGGAATATTTAATGGCATTTTCTAAAGATAAAAAATACAGTTAATAAGGCAAA
GTATGAATATGTGTTATGACTAAAAATGCTTTTTATTTGTAAAGATAATTGGTAATTGTTCAGA
ATTTTTCTCTTAAGTTTGATTCATTCTTTGACTCTGTTATTATAAAATATATGGACTGATACAT
TTTTTATTGTCAACTTCTGAAAGAATGGTTTTGTATCAGTAAACTGATAATTTATCATCATAAA
TAATTTGTTA

hide sequence

RefSeq Acc Id:

XM_017599385 ⟹ XP_017454874

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	3,002,103 - 3,108,567 (+)	NCBI
mRatBN7.2	14	2,857,251 - 2,943,766 (+)	NCBI
Rnor_6.0	14	3,879,689 - 3,961,139 (+)	NCBI

Sequence:

show sequence

TTCCCTCGCGCTCCTTTGGGTGCGTGGTCCCGCAGGGTCTTCACGGAGGAAAGGTTTCTGTCTA
GTCAGTTATGCGTGAACGTCTGCGCTTCTGAAATAAGTATTCATTGTTTGTTTGCAACAGGGTC
CGGCTCTGTAGACCAGGCTATCCCTGCCTGGCTTCCGTCTTCCACCTCTCAAGTGTAGGGATTA
CTGTTGGGAGCCACTGGCGTCTGACTAAATTTCAGACAAAGTCTGTTTTTCAGCAATGCTGGAA
TCAAACGATTGCATTTTATCCATGGATTCTTTGTTTTTCAGTAGCCCAGGTGAAACTGAAAGCT
TTCCAGTTGAGGAAAAATCACTGGATTGGTTTCTCCCTCCAGCTCCACTGATCTCAGAAATTCC
AGATATTCAAGAGTTAGAGGAAGAAATTGAAAATTATAAGCTATTAGGAGAAAGAAAGATGCCC
AATATATTAACATCAAACTTGAAGATCATTAATGAAGACACAAATTGTATTTCACCAACACAGA
AATTCCATTTTCCCTATAACATACATGAACAGGATTACCTAAATTTAGGAGGATTAAATAACAA
TGACATGTCACATACAGCTGGCAAGCTAGTGTACGGTTCTTCTCAAAAATATAAAAACCACATG
GGGGATGAGAGTCCACCGACAAAGAGTGGTCCTGGTGATGCAAAGCTGCATACTGCTGCTGAGG
ACAGAGAGGGCACATCAGCACTCAAAACCAGATTATCTAGAACATGTGGCAGTGTGCAGGAATG
TGACTATGCTAATGGAAATTTAAGCTTGAATTCTCATATTAGCCCAGCGAGACTCACCCAAACA
AAAGTAAGCAAAGAGAAACCATGGAACTGTAGCAATAGAAAACAGAAACTGCAGTATTCTACAG
ACAAATCCAAAGCAAACGATGCTTTTTCTGCTTCTGGAATTGAAAAAGACATATTCGAAGCACC
ATCGTTTTCTGCTGCATCTCAGCCTCGTGACATTCAAGGCATAACCTCAAATGGCTTAGGTTCG
TTGAAGGCTGTCACAGAAATCCCTGCAAAATTTAGAAGTGTATTCAAAGAATTCCCTTACTTCA
ACTATATACAGTCCAAAGCCTTTGATGATCTTCTTTACACAGATCGGAATTTTGTGATTTGTGC
CCCCACTGGTTCTGGGAAAACTGTGGTGTTTGAGCTAGCAATAACAAGATTGTTAATGGAAGCA
CCATTGCCGTGGCTGAACATGAAAGTTGTTTACATGGCACCAATAAAAGCCCTTTGTAGTCAGC
GGTTTGATGACTGGAAAGAAAAATTTGGACCGATAGGCTTGACCTGTAAAGAACTTACTGGAGA
TACAGTAATGGATGACCTGTTTGAGATTCAGCATGCCAATATAATTATGACAACTCCAGAGAAG
TGGGACAGTATGACTAGGAAGTGGAGAGACAACTCCTTCATCCAACTGGTTCGCCTGTTTCTCA
TTGATGAGGTGCATGTTATTAAAGATGAAAACCGTGGTCCAACTCTTGAGGTTGTAGTAAGCAG
AATGAAAACTGTCCAGTCTTTATCTAAGACCTTAGAAAACGCCAGCCCTGCTCCAGTGAGGTTT
GTAGCTGTATCAGCAACAATTCCCAATGCTGAGGATATCGCAGAATGGCTTTCAGATGGGGAGA
GACCTGCTGTGTGTCTGAAAATGGATGAGAGCCACAGACCTGTGAAACTTCAGAAAGTGGTCCT
GGGTTTCCCCAGTAGTAGTAACCAAACTGAATTCAAGTTTGATTTAGCCCTCAACTATAAAGTG
TACAGTGTTATACGAACGTACTCCGATCAGAAGCCCACACTCGTGTTTTGTGCAACGAGGAAAG
GTGTGCAGCAGGCTGCTTCTGTTCTTGTGAAGGACGCTAAGTTTATCATCACCGTGGAGCAGAA
ACTACGGTTGCAGAAGTCTGCATATTCTATAAGGGATTCAAAGCTAAAAGATACCTTGGTGTAC
GGTGTTGGTTACCATCATGCTGGAATGGAGCTGTCAGATAGAAAATTGGTTGAAGAGTTGTTTA
CTTCTGGAGATCTACCAGTTCTTTTTACTACAAGTACTCTAGCTATGGGAGTGAACTTGCCGGC
TCACCTGGTCGTTATAAAGTCCACCATGCACTACACTGGAGGTGCCTTTGAAGAGTACAGCGAG
ACAGACATCCTGCAGATGATTGGAAGAGCTGGCAGGCCCCAGTTTGACACCACAGCTACTGCAG
TTATTATGACCCGACTAAGTACAAGAGAGAAGTACGTTCAGATGCTAGCTTGTAATGACACTGT
GGAAAGCAGTTTGCACAGACATCTTATTGAGCACCTGAACGCAGAGATAGTGCTGCACACCATC
ACAGATGTGAGCATCGCCCTGGACTGGATCCGGTCCACACTGCTGTATATCAGAGCTCTGAAAA
ACCCATCTCACTATGGTTTTATATCTGGATTGAACAAAGATGGAATTGAAGCAAAATTACAAGA
GTTATGTTTGAAGAATCTGAAAGATTTATCATCGCTAGACCTAATAAAGATGGATGAAGACCTT
AATTTCAGATCAACAGAGGCAGGAAGACTAATGGCATGGTATTATATTACATTTGAGACAGTGA
AGAAATTTTGTGCAATCAGTGGAAAAGAAACTTTATCAGATTTGATTTCAATGATATCCAGCTG
CAGTGAGTTTCTAGATGTGCAGCTGAGGATAAGCGAAAAGAGAACACTGAACACACTAAACAAA
GACCCAAACCGGATAACCATCAGATTTCCAATGGAGGGGAGAATTAAAACCAGAGAGATGAAAG
TAAACTGTCTTATTCAGGCTCAGCTAGGATGCATCCCTATACAAGATTTTGCTTTGACACAAGA
TACCTCGAAGATTTTCAGAAATGGCTCACGAATTGCAAAATGGTTGTCAGATTTTGTGACTGCT
CAGGAACAGAAGTTTGCTGTGCTTTTAAACAGTGTGATTTTAGCTAAATGTTTTAAGTGTAAAC
TCTGGGAAAACTCTCAACATGTTTCAAAACAGCTGGATAAAATTGGCATATCATTGTCAAATAC
CATGGTAAATGCAGGCTTGACGTCTTTTAAAAAAATAGAAGAAGCAAATGCGAGAGAACTTGAA
CTGATTTTAAATAGACACCCGCCATTCGGGACCCAGATAAAGGAAGCTGTGATGTATCTGCCAA
AGTATGAACTTGAGGCAGAGCAGATTGCAAGATATAGTGATACCAAGGCAGAAATACTGGTGAC
CATTATATTAAGAAACTTTGAGCAGCTGCAGACCAAAAGAACAGCGCCAGACTTTCACTATGCC
ACCTTAATCATAGGTGATGCAGATAACCAAGTCGTTTGTAAGCACAAAATTATGGATTCTGTCT
TGTTAAAAAGTGGAAATTGGGTTAAAAAAATTGATGTGAAGAGAGCTCTTATATCAGAAGATCT
CAGCATAAATCTAATTAGCTCTGATTATGTTGGTCTTGATATTCACCAGAAATTTACAGTCTTT
TATTTAGGACCCAGGAAGTTTGTAAATCAAACAGTTACGGAAAGAAGCTCAGGAACAGGTCTTT
CTCATTCCGAATGCTCAGACAGAGCTACTGCAGCAGGATCCAGTAAAAGAACGGCTACCTGCAG
AAACCCTGGGAACCGAGAATGCCATCATCACTGTAAAAATAAGCACATATGTGGGCATGACTGC
TGTAAAATTGGAGTTGCACAAAAGCCAGAAGCTAAAGTGTCAGCAGTGTCCTCATATCTGTCTG
ACCTAAAAAGCAGAGATGCTGTTTCTTCTTTTCCCCCAGCTAAGCGACTCAAGATACAGATGAA
CAAATCTCAAAATGTGGACCTTAAAGAATTTGGTTTTGTTCCAAGGCCTTCCCTTTCCAGTATA
GCAAGGTCAGAATATTTAAACATCCATAAATTGCCAATATTAGAACAGAGGACTCAGCATGAGA
TCTATGGCGAAGTTGAAGAGGGAGCGTCTGAATGCCGAGACGAAGCAGACTTTCCCGGATGGGA
CTATTGTGCAGCTTCAAACAAAAGGACCCCAGTGATGCTCAGCAGACATGCTAACACACCTGGA
AACCACGGTGTCGCAGTTGCAGAGAAGAGCAAGTCTTCAGACGGCCCACATGTGAACTCAGAGC
TGGGAGATGAAGTTTGGGATGACTTTGATGATGAAAGCTTAATAGAAGTTATGAGCTTTTCAGC
TGACGCCGAGGAGATGGCTGTGTCAGGGTTTGGAGACACTCGTGATTCAAGTCTAGGCAGAAGT
AAGCTACACTTCGGAAGATCAAGCAGCAGGTTCCAAAGAGACATCTCAAACAGTTTTGTTTCAT
CACCCGAGAAGCCAGATGTTTGTTTGTCAGATTGTTCCGTGTCTAATTTCGGGCTGTCCTCTGT
GGCAGAGTTCCCTCAACAAGCTGGAAATGCAAGTCTTGTCAATTTACAAGAGAGAAAACAGCTG
ACCCTCTCACCAGTGATTGAGAGGATGTGCTTTACCCACTCTGAGAAAATACCACAGTCTCCCA
GTTTTAAGGAAGTGGATATTTTTATTGGAAACAGTGACTCTAAAAAGGAAATTGATCTTAGTAA
GTATTATCCTGATGATGCAGCCGAGGAAATGAAGGCCCTTCTGGGAATATTTAATGGCATTTTC
TAAAGATAAAAAATACAGTTAATAAGGCAAAGTATGAATATGTGTTATGACTAAAAATGCTTTT
TATTTGTAAAGATAATTGGTAATTGTTCAGAATTTTTCTCTTAAGTTTGATTCATTCTTTGACT
CTGTTATTATAAAATATATGGACTGATACATTTTTTATTGTCAACTTCTGAAAGAATGGTTTTG
TATCAGTAAACTGATAATTTATCATCATAAATAATTTGTTA

hide sequence

RefSeq Acc Id:

XM_039092478 ⟹ XP_038948406

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	3,023,482 - 3,108,567 (+)	NCBI
mRatBN7.2	14	2,878,604 - 2,943,766 (+)	NCBI

RefSeq Acc Id:

XM_039092479 ⟹ XP_038948407

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	3,031,580 - 3,108,567 (+)	NCBI
mRatBN7.2	14	2,886,704 - 2,943,766 (+)	NCBI

RefSeq Acc Id:

XM_063273649 ⟹ XP_063129719

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	3,002,103 - 3,108,567 (+)	NCBI

RefSeq Acc Id:

XM_063273650 ⟹ XP_063129720

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	3,002,105 - 3,062,253 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001399493	(Get FASTA)	NCBI Sequence Viewer
	XP_008768170	(Get FASTA)	NCBI Sequence Viewer
	XP_017454874	(Get FASTA)	NCBI Sequence Viewer
	XP_038948406	(Get FASTA)	NCBI Sequence Viewer
	XP_038948407	(Get FASTA)	NCBI Sequence Viewer
	XP_063129719	(Get FASTA)	NCBI Sequence Viewer
	XP_063129720	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034409
	ENSRNOP00000034409.6
	ENSRNOP00000083280.2
	ENSRNOP00000103232
	ENSRNOP00000103232.1
	ENSRNOP00000103638
	ENSRNOP00000103638.1

RefSeq Acc Id:

XP_008768170 ⟸ XM_008769948

- Peptide Label:

isoform X3

- Sequence:

show sequence

MLESNDCILSMDSLFFSSPGETESFPVEEKSLDWFLPPAPLISEIPDIQELEEEIENYKLLGER
KMPNILTSNLKIINEDTNCISPTQKFHFPYNIHEQDYLNLGGLNNNDMSHTAGKLVYGSSQKYK
NHMGDESPPTKSGPGDAKLHTAAEDREGTSALKTRLSRTCGSVQECDYANGNLSLNSHISPARL
TQTKVSKEKPWNCSNRKQKLQYSTDKSKANDAFSASGIEKDIFEAPSFSAASQPRDIQGITSNG
LGSLKAVTEIPAKFRSVFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLL
MEAPLPWLNMKVVYMAPIKALCSQRFDDWKEKFGPIGLTCKELTGDTVMDDLFEIQHANIIMTT
PEKWDSMTRKWRDNSFIQLVRLFLIDEVHVIKDENRGPTLEVVVSRMKTVQSLSKTLENASPAP
VRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPSSSNQTEFKFDLALN
YKVYSVIRTYSDQKPTLVFCATRKGVQQAASVLVKDAKFIITVEQKLRLQKSAYSIRDSKLKDT
LVYGVGYHHAGMELSDRKLVEELFTSGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYTGGAFEE
YSETDILQMIGRAGRPQFDTTATAVIMTRLSTREKYVQMLACNDTVESSLHRHLIEHLNAEIVL
HTITDVSIALDWIRSTLLYIRALKNPSHYGFISGLNKDGIEAKLQELCLKNLKDLSSLDLIKMD
EDLNFRSTEAGRLMAWYYITFETVKKFCAISGKETLSDLISMISSCSEFLDVQLRISEKRTLNT
LNKDPNRITIRFPMEGRIKTREMKVNCLIQAQLGCIPIQDFALTQDTSKIFRNGSRIAKWLSDF
VTAQEQKFAVLLNSVILAKCFKCKLWENSQHVSKQLDKIGISLSNTMVNAGLTSFKKIEEANAR
ELELILNRHPPFGTQIKEAVMYLPKYELEAEQIARYSDTKAEILVTIILRNFEQLQTKRTAPDF
HYATLIIGDADNQVVCKHKIMDSVLLKSGNWVKKIDVKRALISEDLSINLISSDYVGLDIHQKF
TVFYLGPRKFVNQTVTERSSGTGLSHSECSDRATAAGSSKRTATCRNPGNRECHHHCKNKHICG
HDCCKIGVAQKPEAKVSAVSSYLSDLKSRDAVSSFPPAKRLKIQMNKSQNVDLKEFGFVPRPSL
SSIARSEYLNIHKLPILEQRTQHEIYGEVEEGASECRDEASNKRTPVMLSRHANTPGNHGVAVA
EKSKSSDGPHVNSELGDEVWDDFDDESLIEVMSFSADAEEMAVSGFGDTRDSSLGRSKLHFGRS
SSRFQRDISNSFVSSPEKPDVCLSDCSVSNFGLSSVAEFPQQAGNASLVNLQERKQLTLSPVIE
RMCFTHSEKIPQSPSFKEVDIFIGNSDSKKEIDLSKYYPDDAAEEMKALLGIFNGIF

hide sequence

RefSeq Acc Id:

XP_017454874 ⟸ XM_017599385

- Peptide Label:

isoform X1

- Sequence:

show sequence

MLESNDCILSMDSLFFSSPGETESFPVEEKSLDWFLPPAPLISEIPDIQELEEEIENYKLLGER
KMPNILTSNLKIINEDTNCISPTQKFHFPYNIHEQDYLNLGGLNNNDMSHTAGKLVYGSSQKYK
NHMGDESPPTKSGPGDAKLHTAAEDREGTSALKTRLSRTCGSVQECDYANGNLSLNSHISPARL
TQTKVSKEKPWNCSNRKQKLQYSTDKSKANDAFSASGIEKDIFEAPSFSAASQPRDIQGITSNG
LGSLKAVTEIPAKFRSVFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLL
MEAPLPWLNMKVVYMAPIKALCSQRFDDWKEKFGPIGLTCKELTGDTVMDDLFEIQHANIIMTT
PEKWDSMTRKWRDNSFIQLVRLFLIDEVHVIKDENRGPTLEVVVSRMKTVQSLSKTLENASPAP
VRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPSSSNQTEFKFDLALN
YKVYSVIRTYSDQKPTLVFCATRKGVQQAASVLVKDAKFIITVEQKLRLQKSAYSIRDSKLKDT
LVYGVGYHHAGMELSDRKLVEELFTSGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYTGGAFEE
YSETDILQMIGRAGRPQFDTTATAVIMTRLSTREKYVQMLACNDTVESSLHRHLIEHLNAEIVL
HTITDVSIALDWIRSTLLYIRALKNPSHYGFISGLNKDGIEAKLQELCLKNLKDLSSLDLIKMD
EDLNFRSTEAGRLMAWYYITFETVKKFCAISGKETLSDLISMISSCSEFLDVQLRISEKRTLNT
LNKDPNRITIRFPMEGRIKTREMKVNCLIQAQLGCIPIQDFALTQDTSKIFRNGSRIAKWLSDF
VTAQEQKFAVLLNSVILAKCFKCKLWENSQHVSKQLDKIGISLSNTMVNAGLTSFKKIEEANAR
ELELILNRHPPFGTQIKEAVMYLPKYELEAEQIARYSDTKAEILVTIILRNFEQLQTKRTAPDF
HYATLIIGDADNQVVCKHKIMDSVLLKSGNWVKKIDVKRALISEDLSINLISSDYVGLDIHQKF
TVFYLGPRKFVNQTVTERSSGTGLSHSECSDRATAAGSSKRTATCRNPGNRECHHHCKNKHICG
HDCCKIGVAQKPEAKVSAVSSYLSDLKSRDAVSSFPPAKRLKIQMNKSQNVDLKEFGFVPRPSL
SSIARSEYLNIHKLPILEQRTQHEIYGEVEEGASECRDEADFPGWDYCAASNKRTPVMLSRHAN
TPGNHGVAVAEKSKSSDGPHVNSELGDEVWDDFDDESLIEVMSFSADAEEMAVSGFGDTRDSSL
GRSKLHFGRSSSRFQRDISNSFVSSPEKPDVCLSDCSVSNFGLSSVAEFPQQAGNASLVNLQER
KQLTLSPVIERMCFTHSEKIPQSPSFKEVDIFIGNSDSKKEIDLSKYYPDDAAEEMKALLGIFN
GIF

hide sequence

Ensembl Acc Id:

ENSRNOP00000034409 ⟸ ENSRNOT00000033794

RefSeq Acc Id:	XP_038948406 ⟸ XM_039092478
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038948407 ⟸ XM_039092479
- Peptide Label:	isoform X6

Ensembl Acc Id:

ENSRNOP00000083280 ⟸ ENSRNOT00000113420

RefSeq Acc Id:	NP_001399493 ⟸ NM_001412564
- UniProtKB:	F1LWY1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129719 ⟸ XM_063273649
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063129720 ⟸ XM_063273650
- Peptide Label:	isoform X5

Ensembl Acc Id:

ENSRNOP00000103638 ⟸ ENSRNOT00000143122

Ensembl Acc Id:

ENSRNOP00000103232 ⟸ ENSRNOT00000151673

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LWY1-F1-model_v2	AlphaFold	F1LWY1	1-1434	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1584010	AgrOrtholog
BioCyc Gene	G2FUF-16595	BioCyc
Ensembl Genes	ENSRNOG00000023299	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000033794	ENTREZGENE
	ENSRNOT00000033794.7	UniProtKB/TrEMBL
	ENSRNOT00000113420.2	UniProtKB/TrEMBL
	ENSRNOT00000143122	ENTREZGENE
	ENSRNOT00000143122.1	UniProtKB/TrEMBL
	ENSRNOT00000151673	ENTREZGENE
	ENSRNOT00000151673.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
	Sec63 N-terminal domain-like domain	UniProtKB/TrEMBL
InterPro	DEAD-like_helicase	UniProtKB/TrEMBL
	DNA/RNA_helicase_DEAD/DEAH_N	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	Meiotic_Crossover_Helicase	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Sec63-dom	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	690161	ENTREZGENE
PANTHER	HELICASE FOR MEIOSIS 1	UniProtKB/TrEMBL
	HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG	UniProtKB/TrEMBL
Pfam	DEAD	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	Sec63	UniProtKB/TrEMBL
	SNRNP200_wHTH	UniProtKB/TrEMBL
PhenoGen	Hfm1	PhenoGen
PROSITE	HELICASE_ATP_BIND_1	UniProtKB/TrEMBL
	HELICASE_CTER	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000023299	RatGTEx
SMART	DEXDc	UniProtKB/TrEMBL
	HELICc	UniProtKB/TrEMBL
	Sec63	UniProtKB/TrEMBL
Superfamily-SCOP	Sec63 N-terminal domain-like	UniProtKB/TrEMBL
	SSF46785	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8I5ZW98_RAT	UniProtKB/TrEMBL
	A0ABK0LRX5_RAT	UniProtKB/TrEMBL
	A0ABK0LSW0_RAT	UniProtKB/TrEMBL
	F1LWY1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-10	Hfm1	helicase for meiosis 1	Hfm1	HFM1, ATP-dependent DNA helicase homolog	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-07-09	Hfm1	HFM1, ATP-dependent DNA helicase homolog	Hfm1	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Hfm1	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)	LOC690161	similar to HFM1, ATP-dependent DNA helicase homolog	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC690161	similar to HFM1, ATP-dependent DNA helicase homolog	RGD1561458_predicted	similar to novel protein (FLJ36760) (predicted)	Data merged from RGD:1561458	1643240	APPROVED
2006-11-19	LOC690161	similar to HFM1, ATP-dependent DNA helicase homolog			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-07	RGD1561458_predicted	similar to novel protein (FLJ36760) (predicted)	LOC501885	similar to novel protein (FLJ36760)	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC501885	similar to novel protein (FLJ36760)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM