C3h15orf62 (similar to human chromosome 15 open reading frame 62) - Rat Genome Database

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Gene: C3h15orf62 (similar to human chromosome 15 open reading frame 62) Rattus norvegicus
Analyze
Symbol: C3h15orf62
Name: similar to human chromosome 15 open reading frame 62
RGD ID: 1583955
Description: Predicted to enable small GTPase binding activity. Predicted to be involved in Rho protein signal transduction; positive regulation of cellular component biogenesis; and regulation of cell shape. Predicted to be active in cytoplasm; cytoskeleton; and plasma membrane. Orthologous to human C15orf62 (chromosome 15 open reading frame 62); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); 2-hydroxypropanoic acid (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC691418; LOC691418; uncharacterized protein C15orf62 homolog, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83126,618,025 - 126,621,250 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3126,617,606 - 126,626,606 (+)EnsemblGRCr8
mRatBN7.23106,164,179 - 106,167,404 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3106,157,382 - 106,167,831 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3109,837,358 - 109,840,577 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03118,432,896 - 118,436,115 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03116,093,282 - 116,096,501 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03110,980,265 - 110,983,932 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,982,553 - 110,983,098 (+)Ensemblrn6Rnor6.0
Rnor_5.03117,533,188 - 117,534,570 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43105,689,944 - 105,690,489 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3105,075,425 - 105,078,966 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:34800366  


Genomics

Comparative Map Data
C3h15orf62
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83126,618,025 - 126,621,250 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3126,617,606 - 126,626,606 (+)EnsemblGRCr8
mRatBN7.23106,164,179 - 106,167,404 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3106,157,382 - 106,167,831 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3109,837,358 - 109,840,577 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03118,432,896 - 118,436,115 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03116,093,282 - 116,096,501 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03110,980,265 - 110,983,932 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,982,553 - 110,983,098 (+)Ensemblrn6Rnor6.0
Rnor_5.03117,533,188 - 117,534,570 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43105,689,944 - 105,690,489 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3105,075,425 - 105,078,966 (+)NCBICelera
Cytogenetic Map3q35NCBI
C15orf62
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381540,769,980 - 40,772,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1540,769,980 - 40,772,449 (+)Ensemblhg38GRCh38
GRCh371541,062,178 - 41,064,647 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,849,451 - 38,851,942 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1517,830,052 - 17,832,540 (+)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1517,910,304 - 17,912,792 (+)NCBIHuRef
CHM1_11541,182,184 - 41,184,672 (+)NCBICHM1_1
T2T-CHM13v2.01538,576,002 - 38,578,471 (+)NCBIT2T-CHM13v2.0
Gm14137
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392119,004,990 - 119,008,049 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2119,004,990 - 119,008,056 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382119,174,509 - 119,177,568 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,174,509 - 119,177,575 (+)Ensemblmm10GRCm38
MGSCv372119,000,245 - 119,003,311 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362118,865,950 - 118,869,005 (+)NCBIMGSCv36mm8
Celera2120,325,147 - 120,328,216 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.97NCBI
CUNH15orf62
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554167,621,794 - 7,624,837 (+)Ensembl
ChiLan1.0NW_0049554167,621,794 - 7,624,837 (+)NCBIChiLan1.0ChiLan1.0
C16H15orf62
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21630,009,875 - 30,014,688 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11534,160,535 - 34,166,307 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01519,709,049 - 19,713,564 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11537,961,183 - 37,965,684 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1537,963,669 - 37,964,196 (+)EnsemblpanPan2panpan1.1
C30H15orf62
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1307,904,715 - 7,909,042 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl307,907,101 - 7,907,628 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha307,958,451 - 7,963,007 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0308,031,425 - 8,035,986 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1307,954,906 - 7,959,459 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0308,062,147 - 8,066,715 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0308,190,992 - 8,195,549 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH15orf62
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864086,324,442 - 86,328,008 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364714,172,505 - 4,176,071 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C26H15orf62
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12642,234,247 - 42,238,692 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2642,235,652 - 42,236,179 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604898,742,739 - 98,747,183 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH15orf62
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248048,018,533 - 8,020,574 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
C5H15orf62
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1597,352,371 - 97,354,170 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in C3h15orf62
28 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:104
Count of miRNA genes:86
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000030754
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3122654702136118980Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3116582412136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)3125814931139636791Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
RH128082  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23106,165,107 - 106,165,287 (+)MAPPERmRatBN7.2
Rnor_6.03110,982,985 - 110,983,164NCBIRnor6.0
Rnor_5.03117,533,623 - 117,533,802UniSTSRnor5.0
RGSC_v3.43105,690,376 - 105,690,555UniSTSRGSC3.4
Celera3105,078,145 - 105,078,324UniSTS
RH 3.4 Map3913.1UniSTS
Cytogenetic Map3q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 158 91 90 59 92 59 6 354 191 11 137 80 88 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000030754   ⟹   ENSRNOP00000036481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3110,982,553 - 110,983,098 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102261   ⟹   ENSRNOP00000083050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3126,618,305 - 126,622,666 (+)Ensembl
mRatBN7.2 Ensembl3106,157,382 - 106,167,831 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110591   ⟹   ENSRNOP00000086211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3126,617,606 - 126,622,885 (+)Ensembl
mRatBN7.2 Ensembl3106,157,425 - 106,167,831 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000123290   ⟹   ENSRNOP00000112816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3126,618,305 - 126,626,606 (+)Ensembl
RefSeq Acc Id: NM_001399846   ⟹   NP_001386775
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83126,618,025 - 126,621,250 (+)NCBI
mRatBN7.23106,164,179 - 106,167,404 (+)NCBI
RefSeq Acc Id: NM_001399847   ⟹   NP_001386776
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83126,618,025 - 126,621,250 (+)NCBI
mRatBN7.23106,164,179 - 106,167,404 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001386775 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386776 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000083050
  ENSRNOP00000083050.1
  ENSRNOP00000086211.1
  ENSRNOP00000112816
  ENSRNOP00000112816.1
Ensembl Acc Id: ENSRNOP00000036481   ⟸   ENSRNOT00000030754
Ensembl Acc Id: ENSRNOP00000086211   ⟸   ENSRNOT00000110591
Ensembl Acc Id: ENSRNOP00000083050   ⟸   ENSRNOT00000102261
RefSeq Acc Id: NP_001386775   ⟸   NM_001399846
RefSeq Acc Id: NP_001386776   ⟸   NM_001399847
Ensembl Acc Id: ENSRNOP00000112816   ⟸   ENSRNOT00000123290

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZEE8-F1-model_v2 AlphaFold D3ZEE8 1-181 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1583955 AgrOrtholog
BioCyc Gene G2FUF-48214 BioCyc
Ensembl Genes ENSRNOG00000025980 Ensembl
  ENSRNOG00000071065 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000102261 ENTREZGENE
  ENSRNOT00000102261.2 UniProtKB/TrEMBL
  ENSRNOT00000110591.2 UniProtKB/TrEMBL
  ENSRNOT00000123290 ENTREZGENE
  ENSRNOT00000123290.1 UniProtKB/TrEMBL
InterPro Cdc42_Effector_BORG/CEP UniProtKB/TrEMBL
NCBI Gene 691418 ENTREZGENE
PANTHER CDC42 EFFECTOR PROTEIN BORG UniProtKB/TrEMBL
  HYPOTHETICAL PROTEIN LOC691418 UniProtKB/TrEMBL
PhenoGen C3h15orf62 PhenoGen
RatGTEx ENSRNOG00000025980 RatGTEx
  ENSRNOG00000071065 RatGTEx
UniProt A0A8I6A1S9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C3h15orf62  similar to human chromosome 15 open reading frame 62  LOC691418  hypothetical protein LOC691418  Symbol and Name Changed 1299863 APPROVED
2008-01-09 LOC691418  hypothetical protein LOC691418  LOC687734  hypothetical protein LOC687734  Data merged from RGD:1597551 1643240 APPROVED
2006-11-20 LOC687734  hypothetical protein LOC687734      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC691418  hypothetical protein LOC691418      Symbol and Name status set to provisional 70820 PROVISIONAL