C6h14orf180 (similar to human chromosome 14 open reading frame 180) - Rat Genome Database

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Gene: C6h14orf180 (similar to human chromosome 14 open reading frame 180) Rattus norvegicus
Analyze
Symbol: C6h14orf180
Name: similar to human chromosome 14 open reading frame 180
RGD ID: 1583888
Description: Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human C14orf180 (chromosome 14 open reading frame 180); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); arsane (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hypothetical protein LOC691485; LOC691485; nutritionally-regulated adipose and cardiac enriched protein homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86137,378,336 - 137,393,892 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.26131,557,193 - 131,568,245 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6131,559,690 - 131,567,342 (+)EnsemblmRatBN7.2
Rnor_6.06137,063,532 - 137,073,406 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6137,063,611 - 137,071,722 (+)Ensemblrn6Rnor6.0
Rnor_5.06146,072,281 - 146,081,622 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46137,334,554 - 137,337,651 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6129,104,695 - 129,116,943 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:23029450  


Genomics

Comparative Map Data
C6h14orf180
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86137,378,336 - 137,393,892 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.26131,557,193 - 131,568,245 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6131,559,690 - 131,567,342 (+)EnsemblmRatBN7.2
Rnor_6.06137,063,532 - 137,073,406 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6137,063,611 - 137,071,722 (+)Ensemblrn6Rnor6.0
Rnor_5.06146,072,281 - 146,081,622 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46137,334,554 - 137,337,651 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6129,104,695 - 129,116,943 (+)NCBICelera
Cytogenetic Map6q32NCBI
C14orf180
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814104,579,764 - 104,590,515 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14104,579,550 - 104,590,515 (+)Ensemblhg38GRCh38
GRCh3714105,046,101 - 105,056,852 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614104,117,101 - 104,127,228 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1485,102,104 - 85,112,230 (+)NCBICelera
Cytogenetic Map14q32.33NCBI
HuRef1485,242,537 - 85,252,655 (+)NCBIHuRef
CHM1_114104,983,579 - 104,993,697 (+)NCBICHM1_1
T2T-CHM13v2.01498,822,545 - 98,833,296 (+)NCBIT2T-CHM13v2.0
A530016L24Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912112,455,829 - 112,466,362 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12112,455,882 - 112,466,361 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3812112,489,394 - 112,499,928 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12112,489,448 - 112,499,927 (+)Ensemblmm10GRCm38
MGSCv3712113,727,659 - 113,738,138 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612112,937,275 - 112,946,924 (+)NCBIMGSCv36mm8
Celera12113,692,488 - 113,708,980 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.2NCBI
LOC102023845
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555383,080,112 - 3,082,282 (+)Ensembl
ChiLan1.0NW_0049555383,076,578 - 3,083,867 (+)NCBIChiLan1.0ChiLan1.0
C15H14orf180
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215105,761,293 - 105,771,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114104,977,794 - 104,988,438 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01485,226,995 - 85,242,300 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114105,023,406 - 105,033,370 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14105,023,477 - 105,033,370 (+)EnsemblpanPan2panpan1.1
C8H14orf180
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1872,165,757 - 72,176,235 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl872,165,810 - 72,176,264 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha871,673,440 - 71,683,364 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0872,442,501 - 72,452,430 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl872,442,530 - 72,452,425 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1872,129,069 - 72,138,959 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0872,168,457 - 72,178,369 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0872,567,856 - 72,577,782 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH14orf180
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086401,952,189 - 1,961,184 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936621781,145 - 790,441 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CUnH14orf180
(Sus scrofa - pig)		 No map positions available.
C24H14orf180
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12482,509,386 - 82,522,929 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2482,513,692 - 82,522,935 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605369,858,945 - 69,877,583 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH14orf180
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624734636,582 - 643,656 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
C7H14orf180
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17130,092,573 - 130,099,681 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in C6h14orf180
50 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:72
Count of miRNA genes:66
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000017504
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6131392689143944780Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat

Markers in Region
RH142983  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26131,567,309 - 131,567,451 (+)MAPPERmRatBN7.2
Rnor_6.06137,071,706 - 137,071,846NCBIRnor6.0
Rnor_5.06146,079,922 - 146,080,062UniSTSRnor5.0
RGSC_v3.46137,337,680 - 137,337,820UniSTSRGSC3.4
Celera6129,115,243 - 129,115,383UniSTS
RH 3.4 Map6783.4UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 11 67 88 62 61 30 26 30 6 229 124 10 61 56 72 31 5 5

Sequence


Ensembl Acc Id: ENSRNOT00000017504   ⟹   ENSRNOP00000017504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6131,559,690 - 131,567,342 (+)Ensembl
Rnor_6.0 Ensembl6137,063,611 - 137,071,722 (+)Ensembl
RefSeq Acc Id: XM_001078490   ⟹   XP_001078490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,380,807 - 137,393,892 (+)NCBI
mRatBN7.26131,559,477 - 131,568,245 (+)NCBI
Rnor_6.06137,063,533 - 137,073,406 (+)NCBI
Rnor_5.06146,072,281 - 146,081,622 (+)NCBI
RGSC_v3.46137,334,554 - 137,337,651 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240652   ⟹   XP_006240714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,380,919 - 137,393,892 (+)NCBI
mRatBN7.26131,559,474 - 131,568,245 (+)NCBI
Rnor_6.06137,063,532 - 137,073,406 (+)NCBI
Rnor_5.06146,072,281 - 146,081,622 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039113393   ⟹   XP_038969321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,378,346 - 137,393,892 (+)NCBI
mRatBN7.26131,557,211 - 131,568,245 (+)NCBI
RefSeq Acc Id: XM_039113394   ⟹   XP_038969322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,379,016 - 137,393,892 (+)NCBI
mRatBN7.26131,557,220 - 131,568,245 (+)NCBI
RefSeq Acc Id: XM_039113395   ⟹   XP_038969323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,378,350 - 137,393,892 (+)NCBI
mRatBN7.26131,557,216 - 131,568,245 (+)NCBI
RefSeq Acc Id: XM_039113396   ⟹   XP_038969324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,378,346 - 137,393,892 (+)NCBI
mRatBN7.26131,557,212 - 131,568,245 (+)NCBI
RefSeq Acc Id: XM_039113398   ⟹   XP_038969326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,378,950 - 137,393,892 (+)NCBI
mRatBN7.26131,557,211 - 131,568,245 (+)NCBI
RefSeq Acc Id: XM_039113399   ⟹   XP_038969327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,378,336 - 137,388,171 (+)NCBI
mRatBN7.26131,557,193 - 131,567,038 (+)NCBI
RefSeq Acc Id: XP_001078490   ⟸   XM_001078490
- Peptide Label: isoform X2
- UniProtKB: D3ZEU6 (UniProtKB/TrEMBL),   A6KBV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240714   ⟸   XM_006240652
- Peptide Label: isoform X2
- UniProtKB: D3ZEU6 (UniProtKB/TrEMBL),   A6KBV0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017504   ⟸   ENSRNOT00000017504
RefSeq Acc Id: XP_038969327   ⟸   XM_039113399
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038969326   ⟸   XM_039113398
- Peptide Label: isoform X2
- UniProtKB: D3ZEU6 (UniProtKB/TrEMBL),   A6KBV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969321   ⟸   XM_039113393
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038969324   ⟸   XM_039113396
- Peptide Label: isoform X2
- UniProtKB: D3ZEU6 (UniProtKB/TrEMBL),   A6KBV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969323   ⟸   XM_039113395
- Peptide Label: isoform X2
- UniProtKB: D3ZEU6 (UniProtKB/TrEMBL),   A6KBV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969322   ⟸   XM_039113394
- Peptide Label: isoform X2
- UniProtKB: D3ZEU6 (UniProtKB/TrEMBL),   A6KBV0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZEU6-F1-model_v2 AlphaFold D3ZEU6 1-170 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1583888 AgrOrtholog
BioCyc Gene G2FUF-35792 BioCyc
Ensembl Genes ENSRNOG00000013097 Ensembl
  ENSRNOG00000085756 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000131027 ENTREZGENE
  ENSRNOT00000131027.1 UniProtKB/TrEMBL
  ENSRNOT00000133863 ENTREZGENE
  ENSRNOT00000133863.1 UniProtKB/TrEMBL
InterPro DUF4658 UniProtKB/TrEMBL
KEGG Report rno:691485 UniProtKB/TrEMBL
NCBI Gene 691485 ENTREZGENE
PANTHER NUTRITIONALLY-REGULATED ADIPOSE AND CARDIAC ENRICHED PROTEIN HOMOLOG UniProtKB/TrEMBL
  PTHR36868 UniProtKB/TrEMBL
Pfam DUF4658 UniProtKB/TrEMBL
PhenoGen C6h14orf180 PhenoGen
RatGTEx ENSRNOG00000013097 RatGTEx
  ENSRNOG00000085756 RatGTEx
UniProt A0ABK0LEH8_RAT UniProtKB/TrEMBL
  A0ABK0M4W2_RAT UniProtKB/TrEMBL
  A6KBV0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZEU6 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-30 C6h14orf180  similar to human chromosome 14 open reading frame 180  LOC691485  hypothetical protein LOC691485  Name and Symbol changed 629549 APPROVED
2008-01-09 LOC691485  hypothetical protein LOC691485  LOC684950  hypothetical protein LOC684950  Data merged from RGD:1584406 1643240 APPROVED
2006-11-19 LOC691485  hypothetical protein LOC691485      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684950  hypothetical protein LOC684950      Symbol and Name status set to provisional 70820 PROVISIONAL