Abracl (ABRA C-terminal like) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Abracl (ABRA C-terminal like) Rattus norvegicus
Analyze
Symbol: Abracl
Name: ABRA C-terminal like
RGD ID: 1583256
Description: Predicted to be involved in regulation of actin filament-based process. Orthologous to human ABRACL (ABRA C-terminal like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: costars family protein ABRACL; hypothetical protein LOC685045; LOC685045; similar to Protein C6orf115; uncharacterized protein LOC685045
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8114,474,802 - 14,484,992 (-)NCBIGRCr8
mRatBN7.2112,654,951 - 12,665,143 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl112,654,838 - 12,665,207 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx112,426,988 - 12,437,196 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0118,428,914 - 18,439,123 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0112,635,289 - 12,645,481 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0113,165,583 - 13,175,773 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl113,165,572 - 13,175,876 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0114,859,230 - 14,869,420 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4113,063,558 - 13,073,748 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera111,112,403 - 11,122,593 (-)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Abracl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8114,474,802 - 14,484,992 (-)NCBIGRCr8
mRatBN7.2112,654,951 - 12,665,143 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl112,654,838 - 12,665,207 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx112,426,988 - 12,437,196 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0118,428,914 - 18,439,123 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0112,635,289 - 12,645,481 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0113,165,583 - 13,175,773 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl113,165,572 - 13,175,876 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0114,859,230 - 14,869,420 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4113,063,558 - 13,073,748 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera111,112,403 - 11,122,593 (-)NCBICelera
Cytogenetic Map1p12NCBI
ABRACL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386139,028,745 - 139,043,302 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6139,028,745 - 139,043,302 (+)EnsemblGRCh38hg38GRCh38
GRCh376139,349,882 - 139,364,439 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366139,391,512 - 139,406,132 (+)NCBINCBI36Build 36hg18NCBI36
Celera6140,089,868 - 140,104,496 (+)NCBICelera
Cytogenetic Map6q24.1NCBI
HuRef6136,911,451 - 136,925,964 (+)NCBIHuRef
CHM1_16139,612,858 - 139,627,484 (+)NCBICHM1_1
T2T-CHM13v2.06140,215,028 - 140,231,830 (+)NCBIT2T-CHM13v2.0
Abracl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391017,887,008 - 17,899,000 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1017,887,008 - 17,899,036 (-)EnsemblGRCm39 Ensembl
GRCm381018,011,260 - 18,023,252 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1018,011,260 - 18,023,288 (-)EnsemblGRCm38mm10GRCm38
MGSCv371017,731,066 - 17,743,058 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361017,700,677 - 17,728,665 (-)NCBIMGSCv36mm8
Celera1017,909,262 - 17,921,258 (-)NCBICelera
Cytogenetic Map10A3NCBI
cM Map107.39NCBI
Abracl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543620,634,071 - 20,645,609 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543620,634,128 - 20,645,609 (-)NCBIChiLan1.0ChiLan1.0
ABRACL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25158,996,095 - 159,010,940 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16156,890,068 - 156,904,672 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06136,789,968 - 136,804,723 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16140,871,265 - 140,885,938 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6140,871,264 - 140,889,288 (+)Ensemblpanpan1.1panPan2
ABRACL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1131,254,959 - 31,267,167 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl131,254,551 - 31,275,981 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha132,128,027 - 32,140,741 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0131,415,757 - 31,428,486 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl131,416,541 - 31,428,489 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1131,291,698 - 31,304,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0131,173,987 - 31,186,660 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0131,485,157 - 31,498,022 (+)NCBIUU_Cfam_GSD_1.0
Abracl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946126,299,375 - 126,311,342 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365606,078,625 - 6,090,612 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365606,078,659 - 6,090,222 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABRACL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,432,706 - 25,447,594 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,432,314 - 25,447,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2128,570,439 - 28,585,808 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABRACL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11334,354,533 - 34,369,070 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1334,354,279 - 34,364,673 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660406,497,900 - 6,512,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abracl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475314,922,862 - 14,935,567 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475314,923,097 - 14,935,432 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abracl
116 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:30
Count of miRNA genes:27
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000016618
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat

Markers in Region
RH139648  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2112,655,303 - 12,655,503 (+)MAPPERmRatBN7.2
Rnor_6.0113,165,936 - 13,166,135NCBIRnor6.0
Rnor_5.0114,859,583 - 14,859,782UniSTSRnor5.0
RGSC_v3.4113,063,911 - 13,064,110UniSTSRGSC3.4
Celera111,112,756 - 11,112,955UniSTS
RH 3.4 Map1129.81UniSTS
Cytogenetic Map1p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000084870   ⟹   ENSRNOP00000074648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl112,654,838 - 12,665,207 (-)Ensembl
Rnor_6.0 Ensembl113,165,572 - 13,175,876 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103174   ⟹   ENSRNOP00000095788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl112,654,838 - 12,659,469 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107631   ⟹   ENSRNOP00000083184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl112,654,952 - 12,664,166 (-)Ensembl
RefSeq Acc Id: NM_001099647   ⟹   NP_001093117
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8114,474,802 - 14,484,992 (-)NCBI
mRatBN7.2112,654,951 - 12,665,143 (-)NCBI
Rnor_6.0113,165,583 - 13,175,773 (-)NCBI
Rnor_5.0114,859,230 - 14,869,420 (-)NCBI
RGSC_v3.4113,063,558 - 13,073,748 (-)RGD
Celera111,112,403 - 11,122,593 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001093117 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH89921 (Get FASTA)   NCBI Sequence Viewer  
  EDL93765 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074648.2
  ENSRNOP00000083184.1
  ENSRNOP00000095788.1
RefSeq Acc Id: NP_001093117   ⟸   NM_001099647
- UniProtKB: A6JP93 (UniProtKB/TrEMBL),   A6JP92 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074648   ⟸   ENSRNOT00000084870
Ensembl Acc Id: ENSRNOP00000095788   ⟸   ENSRNOT00000103174
Ensembl Acc Id: ENSRNOP00000083184   ⟸   ENSRNOT00000107631
Protein Domains
Costars

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSL2-F1-model_v2 AlphaFold D3ZSL2 1-81 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689504
Promoter ID:EPDNEW_R29
Type:initiation region
Name:Abracl_1
Description:ABRA C-terminal like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0113,175,805 - 13,175,865EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1583256 AgrOrtholog
BioCyc Gene G2FUF-62280 BioCyc
Ensembl Genes ENSRNOG00000051450 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084870.2 UniProtKB/TrEMBL
  ENSRNOT00000103174.1 UniProtKB/TrEMBL
  ENSRNOT00000107631.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1540 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7306744 IMAGE-MGC_LOAD
InterPro Costars UniProtKB/TrEMBL
  Costars_dom UniProtKB/TrEMBL
  Costars_sf UniProtKB/TrEMBL
KEGG Report rno:685045 UniProtKB/TrEMBL
MGC_CLONE MGC:109201 IMAGE-MGC_LOAD
NCBI Gene 685045 ENTREZGENE
PANTHER COSTARS FAMILY PROTEIN ABRACL UniProtKB/TrEMBL
  PTHR46334 UniProtKB/TrEMBL
Pfam Costars UniProtKB/TrEMBL
PhenoGen Abracl PhenoGen
RatGTEx ENSRNOG00000051450 RatGTEx
SMART Costars UniProtKB/TrEMBL
UniProt A0A8I6G8K6_RAT UniProtKB/TrEMBL
  A6JP92 ENTREZGENE, UniProtKB/TrEMBL
  A6JP93 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSL2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-09-26 Abracl  ABRA C-terminal like  LOC685045  similar to Protein C6orf115  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC685045  similar to Protein C6orf115      Symbol and Name status set to provisional 70820 PROVISIONAL