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Gene: Mcts1 (MCTS1, re-initiation and release factor) Rattus norvegicus

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Symbol:

Mcts1

Name:

MCTS1, re-initiation and release factor

RGD ID:

1566390

Description:

Predicted to enable RNA cap binding activity; ribosomal small subunit binding activity; and translation initiation factor activity. Predicted to be involved in IRES-dependent viral translational initiation; cytoplasmic translational initiation; and ribosome disassembly. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 118. Orthologous to human MCTS1 (MCTS1 re-initiation and release factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

malignant T cell amplified sequence 1; malignant T cell-amplified sequence 1; malignant T-cell-amplified sequence 1; MCT-1; MGC112904

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MCTS1 (MCTS1 re-initiation and release factor)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Mcts1 (malignant T cell amplified sequence 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mcts1 (MCTS1 re-initiation and release factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MCTS1 (MCTS1 re-initiation and release factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MCTS1 (MCTS1 re-initiation and release factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mcts1 (MCTS1 re-initiation and release factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOC100738684 (malignant T-cell-amplified sequence 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MCTS1 (MCTS1 re-initiation and release factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mcts1 (MCTS1 re-initiation and release factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mcts1 (MCTS1 re-initiation and release factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MCTS2 (MCTS family member 2)	HGNC	Ensembl, OrthoDB
Alliance orthologs ³
Homo sapiens (human):	MCTS1 (MCTS1 re-initiation and release factor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MCTS1 (MCTS1 re-initiation and release factor)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Mus musculus (house mouse):	Mcts1 (malignant T cell amplified sequence 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Mcts1 (malignant T cell amplified sequence 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	mcts1 (MCTS1 re-initiation and release factor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C11D2.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	MCTS1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TMA20	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mcts1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	122,215,602 - 122,228,101 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	122,216,439 - 122,229,631 (+)	Ensembl				GRCr8
mRatBN7.2	X	117,350,723 - 117,362,504 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	117,350,889 - 117,362,504 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	119,449,520 - 119,460,948 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	123,018,531 - 123,029,961 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	120,563,663 - 120,575,063 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	124,894,269 - 124,906,129 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	124,894,466 - 124,906,162 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	124,978,932 - 124,990,624 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	6,764,788 - 6,776,128 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	116,567,429 - 116,578,676 (+)	NCBI		Celera
Cytogenetic Map	X	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

immunodeficiency 118 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dimethoxyphenol (ISO)

2-methylcholine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

acetamide (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

cadmium dichloride (ISO)

clofibric acid (EXP)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

disodium selenite (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

eugenol (ISO)

fenthion (ISO)

folic acid (ISO)

furfural (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

isotretinoin (ISO)

ivermectin (ISO)

methidathion (ISO)

methotrexate (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

quercitrin (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sunitinib (ISO)

thapsigargin (EXP)

thioacetamide (EXP)

tolcapone (EXP)

trichloroethene (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IEA)

formation of translation preinitiation complex (IBA,ISO)

IRES-dependent viral translational initiation (ISO)

ribosome disassembly (ISO,ISS)

translation reinitiation (IEA,ISO,ISS)

Cellular Component

cytoplasm (IEA,ISO,ISS)

cytosol (ISO)

Molecular Function

protein binding (ISO)

ribosomal small subunit binding (ISO,ISS)

RNA binding (IEA)

RNA cap binding (ISO,ISS)

translation initiation factor activity (ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:16854843	PMID:20713520	PMID:32160403

Genomics

Comparative Map Data

Mcts1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	122,215,602 - 122,228,101 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	122,216,439 - 122,229,631 (+)	Ensembl				GRCr8
mRatBN7.2	X	117,350,723 - 117,362,504 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	117,350,889 - 117,362,504 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	119,449,520 - 119,460,948 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	123,018,531 - 123,029,961 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	120,563,663 - 120,575,063 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	124,894,269 - 124,906,129 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	124,894,466 - 124,906,162 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	124,978,932 - 124,990,624 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	6,764,788 - 6,776,128 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	116,567,429 - 116,578,676 (+)	NCBI		Celera
Cytogenetic Map	X	q35	NCBI

MCTS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	120,604,101 - 120,621,159 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	120,594,010 - 120,621,159 (+)	Ensembl			hg38	GRCh38
GRCh37	X	119,737,956 - 119,755,014 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	119,621,863 - 119,630,270 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	119,519,716 - 119,528,120	NCBI
Celera	X	120,202,071 - 120,219,337 (+)	NCBI		Celera
Cytogenetic Map	X	q24	NCBI
HuRef	X	109,209,081 - 109,219,526 (+)	NCBI		HuRef
HuRef	X	109,189,067 - 109,206,050 (+)	NCBI		HuRef
CHM1_1	X	119,649,376 - 119,666,661 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	118,979,555 - 118,996,612 (+)	NCBI		T2T-CHM13v2.0

Mcts1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	37,653,682 - 37,702,401 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	37,689,455 - 37,702,303 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	38,600,471 - 38,613,524 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	38,600,578 - 38,613,426 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	35,953,835 - 35,966,699 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	34,845,285 - 34,858,149 (+)	NCBI		MGSCv36	mm8
Celera	X	26,246,762 - 26,259,560 (+)	NCBI		Celera
Cytogenetic Map	X	A3.3	NCBI
cM Map	X	22.88	NCBI

Mcts1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955572	1,272,870 - 1,285,445 (-)	Ensembl
ChiLan1.0	NW_004955572	1,272,870 - 1,285,190 (-)	NCBI	ChiLan1.0	ChiLan1.0

MCTS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	120,158,797 - 120,167,286 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	120,162,470 - 120,179,638 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	109,883,634 - 109,900,840 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	120,070,009 - 120,087,004 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	120,070,009 - 120,078,376 (+)	Ensembl			panPan2	panpan1.1

MCTS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	92,559,648 - 92,574,576 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	92,559,899 - 92,570,366 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	78,590,298 - 78,609,158 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	94,305,096 - 94,323,951 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	94,306,181 - 94,318,997 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	91,754,318 - 91,773,178 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	93,516,883 - 93,535,738 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	93,291,758 - 93,310,612 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mcts1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	91,545,024 - 91,562,606 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936479	9,432,817 - 9,442,447 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936479	9,432,817 - 9,491,615 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC100738684
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	10	65,704,921 - 65,705,734 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	72,133,600 - 72,134,400 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MCTS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666065	33,320,595 - 33,329,226 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mcts1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624931	518,804 - 530,249 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624931	518,925 - 529,996 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mcts1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	101,771,315 - 101,781,386 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mcts1
40 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	31
Count of miRNA genes:	31
Interacting mature miRNAs:	31
Transcripts:	ENSRNOT00000066677
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598856	Memor1	Memory QTL 1	1.9		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	X	120028026	141353710	Rat
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	97528096	142528096	Rat
1598809	Memor15	Memory QTL 15	4.4		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	120028026	141353710	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	105359969	157758123	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	80434318	125434318	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	105468858	125434318	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	118973754	157758123	Rat
2302047	Pia34	Pristane induced arthritis QTL 34	5.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	19	96916163	141916163	Rat

Markers in Region

DXS8324

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	117,362,343 - 117,362,465 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	124,905,969 - 124,906,090	NCBI	Rnor6.0
Rnor_5.0	X	124,990,464 - 124,990,585	UniSTS	Rnor5.0
RGSC_v3.4	X	6,764,827 - 6,764,948	UniSTS	RGSC3.4
Celera	X	116,578,516 - 116,578,637	UniSTS
Cytogenetic Map	X	q11	UniSTS

RH143993

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	117,358,385 - 117,358,590 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	124,902,011 - 124,902,215	NCBI	Rnor6.0
Rnor_5.0	X	124,986,506 - 124,986,710	UniSTS	Rnor5.0
RGSC_v3.4	X	6,768,702 - 6,768,906	UniSTS	RGSC3.4
Celera	X	116,574,575 - 116,574,779	UniSTS
Cytogenetic Map	X	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001044237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001434002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001434003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC098848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000066677 ⟹ ENSRNOP00000061717

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	122,217,091 - 122,229,631 (+)	Ensembl
mRatBN7.2 Ensembl	X	117,351,080 - 117,362,500 (+)	Ensembl
Rnor_6.0 Ensembl	X	124,894,706 - 124,906,125 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000080894 ⟹ ENSRNOP00000074032

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	122,216,439 - 122,228,096 (+)	Ensembl
mRatBN7.2 Ensembl	X	117,350,889 - 117,362,504 (+)	Ensembl
Rnor_6.0 Ensembl	X	124,894,466 - 124,906,162 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113941 ⟹ ENSRNOP00000090518

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	117,351,500 - 117,362,504 (+)	Ensembl

RefSeq Acc Id:

NM_001044237 ⟹ NP_001037702

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	122,216,677 - 122,228,101 (+)	NCBI
mRatBN7.2	X	117,351,080 - 117,362,504 (+)	NCBI
Rnor_6.0	X	124,894,706 - 124,906,129 (+)	NCBI
Rnor_5.0	X	124,978,932 - 124,990,624 (+)	NCBI
RGSC_v3.4	X	6,764,788 - 6,776,128 (-)	RGD
Celera	X	116,567,429 - 116,578,676 (+)	RGD

Sequence:

show sequence

GAGGGAGAGAGCAAAGGTCCTCTTTCTCTCTCCCCCGCCCCTGCCATCCTGACTTCTAAGGTTT
TGTAAATATAGTACTATGCTCTCACTCCGGACTTGGAACACTTCTTTAAGCTTTCCATCCTTAA
TCCTCAATCGGGTTTGGCTCTCCCGCTCCCATTTCCTTTCTCCTTAGCCCTGTTCTGCCCCCTC
CGCCAGTGCTATCTCCATTCCTAGGTTTCTACCAATCACATCCTTGCACTGTGATTTAGGGGCA
CATCCTTAGTTGAGAGGAGAGCCCTGCACTCTCTGCCATATGTTTATTAGTTATGAACTGAAAA
AGGGAAGGCTTGACTTCCTGGGTCATGGCAGCGAAGGAGTCTGGGTGACAGGAAGCAAGCGGCT
GGTCTGTCAAGCCTATTGCTTAGCTGCTAGATTAACCTTGTCTTGAGAACAACGTGGTAGCCCT
GTGTGCTAGTCAGTGTAAGGAAGACCAAATTCCTTGGAAACCTATTCAGTGGGTTTATCTTCCA
GATTTGATAGACGCAAAAAGAAAAAGGGGAAACATGGGCAAAGGAAGATTTGATGAAAAAGAAA
ATGTGTCCAACTGCATCCAGTTGAAAACCTCGGTTATTAAGGGTATTAAAAATCAATTGCTAGA
GCAATTTCCAGGTATTGAACCATGGCTTAATCAAATCATGCCTAAGAAAGATCCTGTGAAAATT
GTCCGATGCCATGAACACATAGAAATCCTTACAGTAAATGGAGAGTTACTGTTTTTTAGACAAA
GAGAAGGGCCTTTTTATCCAACCTTAAGATTACTTCATAAATATCCTTTTATCTTGCCACATCA
GCAGGTTGATAAAGGAGCCATCAAATTTGTACTCAGTGGAGCAAATATCATGTGTCCCGGCTTA
ACGTCTCCTGGAGCTAAGCTTTATCCTGCTGCAGTAGATACTATTGTTGCAATCATGGCAGAAG
GAAAACAACATGCTTTATGTGTGGGCGTCATGAAGATGTCTGCAGAAGATATTGAGAAAGTCAA
CAAAGGAATTGGCATTGAAAATATCCATTATCTAAATGATGGGCTGTGGCATATGAAGACATAT
AAATGAGCTTCCAAAGGAATGTGCTTGGGCTAACTATAGATACTGTGCTGTATCTGTCTCTGTG
TCTGTATGACAGCATGAAGACAATGCCTCTATGGTTATGCTGAATAAAAATTCTGTGAATGCTA
AAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006257488 ⟹ XP_006257550

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	122,215,602 - 122,228,101 (+)	NCBI
mRatBN7.2	X	117,350,737 - 117,362,504 (+)	NCBI
Rnor_6.0	X	124,894,269 - 124,906,129 (+)	NCBI
Rnor_5.0	X	124,978,932 - 124,990,624 (+)	NCBI

Sequence:

show sequence

CCGGTAACTGATTGCCACAATTTCTGCTTTGATTGATTTCCTCCCTCCTCCATTCTTCTCTTCC
AGCCACCAGAAAGAATTGTTTGATCACTTCTTCCTTCTGAAGTCCCGCCCTTTCGGCTACCCCC
AATGGAGAATAAGCTGTTACTGAAAAGGAGCGGACAAAAGCGTCAACGTGGAGGCGAGAGGAGC
GGAAGTAGTCAGATTTCGCATAGGGCCGTAAAGCGGATAGTGTTTTCGCCTTCCGGATTAACGA
CAGCAGCTCAGACTGTCAGTGCCGGCCTTCCTTGTGCCGGACCCTTCCTAATTCAATTTCCTTC
CCATTCCGGGCCCTTCCCTATCGTCGCCCCTTTCACCTTGGATCATGTTCAAGAAATTTGATGA
AAAAGAAAATGTGTCCAACTGCATCCAGTTGAAAACCTCGGTTATTAAGGGTATTAAAAATCAA
TTGCTAGAGCAATTTCCAGGTATTGAACCATGGCTTAATCAAATCATGCCTAAGAAAGATCCTG
TGAAAATTGTCCGATGCCATGAACACATAGAAATCCTTACAGTAAATGGAGAGTTACTGTTTTT
TAGACAAAGAGAAGGGCCTTTTTATCCAACCTTAAGATTACTTCATAAATATCCTTTTATCTTG
CCACATCAGCAGGTTGATAAAGGAGCCATCAAATTTGTACTCAGTGGAGCAAATATCATGTGTC
CCGGCTTAACGTCTCCTGGAGCTAAGCTTTATCCTGCTGCAGTAGATACTATTGTTGCAATCAT
GGCAGAAGGAAAACAACATGCTTTATGTGTGGGCGTCATGAAGATGTCTGCAGAAGATATTGAG
AAAGTCAACAAAGGAATTGGCATTGAAAATATCCATTATCTAAATGATGGGCTGTGGCATATGA
AGACATATAAATGAGCTTCCAAAGGAATGTGCTTGGGCTAACTATAGATACTGTGCTGTATCTG
TCTCTGTGTCTGTATGACAGCATGAAGACAATGCCTCTATGGTTATGCTGAATAAAAATTCTGT
GAATGCTAAAA

hide sequence

RefSeq Acc Id:

XM_039099623 ⟹ XP_038955551

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	122,215,602 - 122,228,101 (+)	NCBI
mRatBN7.2	X	117,350,723 - 117,362,504 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001037702	(Get FASTA)	NCBI Sequence Viewer
	NP_001420931	(Get FASTA)	NCBI Sequence Viewer
	NP_001420932	(Get FASTA)	NCBI Sequence Viewer
	XP_006257550	(Get FASTA)	NCBI Sequence Viewer
	XP_038955551	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98848	(Get FASTA)	NCBI Sequence Viewer
	EDM10868	(Get FASTA)	NCBI Sequence Viewer
	EDM10869	(Get FASTA)	NCBI Sequence Viewer
	EDM10870	(Get FASTA)	NCBI Sequence Viewer
	EDM10871	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000061717
	ENSRNOP00000061717.1
	ENSRNOP00000074032
GenBank Protein	Q4G009	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001037702 ⟸ NM_001044237
- UniProtKB:	Q4G009 (UniProtKB/Swiss-Prot), A6JMK9 (UniProtKB/TrEMBL), A0A8I6ADP8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGKGRFDEKENVSNCIQLKTSVIKGIKNQLLEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILT VNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAA VDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK hide sequence

RefSeq Acc Id:	XP_006257550 ⟸ XM_006257488
- Peptide Label:	isoform X1
- Sequence:	show sequence MFKKFDEKENVSNCIQLKTSVIKGIKNQLLEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTV NGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAV DTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK hide sequence

Ensembl Acc Id:

ENSRNOP00000074032 ⟸ ENSRNOT00000080894

Ensembl Acc Id:

ENSRNOP00000061717 ⟸ ENSRNOT00000066677

RefSeq Acc Id:	XP_038955551 ⟸ XM_039099623
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000090518 ⟸ ENSRNOT00000113941

Protein Domains

PUA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4G009-F1-model_v2	AlphaFold	Q4G009	1-182	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13702000

Promoter ID:

EPDNEW_R12523

Type:

initiation region

Name:

Mcts1_1

Description:

MCTS1, re-initiation and release factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	124,894,534 - 124,894,594	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1566390	AgrOrtholog
BioCyc Gene	G2FUF-1256	BioCyc
Ensembl Genes	ENSRNOG00000002563	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000066677	ENTREZGENE
	ENSRNOT00000066677.2	UniProtKB/Swiss-Prot
	ENSRNOT00000080894	ENTREZGENE
Gene3D-CATH	3.10.400.20	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7379624	IMAGE-MGC_LOAD
InterPro	MCT-1/Tma20	UniProtKB/Swiss-Prot
	Pre-PUA	UniProtKB/Swiss-Prot
	PUA	UniProtKB/Swiss-Prot
	PUA-like_sf	UniProtKB/Swiss-Prot
	Uncharacterised_CHP00451	UniProtKB/Swiss-Prot
KEGG Report	rno:302500	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:112904	IMAGE-MGC_LOAD
NCBI Gene	302500	ENTREZGENE
PANTHER	MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1	UniProtKB/Swiss-Prot
	PTHR22798	UniProtKB/Swiss-Prot
Pfam	Pre-PUA	UniProtKB/Swiss-Prot
	PUA	UniProtKB/Swiss-Prot
PhenoGen	Mcts1	PhenoGen
PIRSF	Tma_RNA-bind_prd	UniProtKB/Swiss-Prot
PROSITE	PUA	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000002563	RatGTEx
SMART	PUA	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF88697	UniProtKB/Swiss-Prot
UniProt	A0A0G2K724	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ADP8	ENTREZGENE
	A6JMK6_RAT	UniProtKB/TrEMBL
	A6JMK7	ENTREZGENE, UniProtKB/TrEMBL
	A6JMK8	ENTREZGENE, UniProtKB/TrEMBL
	A6JMK9	ENTREZGENE, UniProtKB/TrEMBL
	MCTS1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-27	Mcts1	MCTS1, re-initiation and release factor	Mcts1	malignant T cell amplified sequence 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Mcts1	malignant T cell amplified sequence 1			Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	Mcts1	malignant T cell amplified sequence 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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