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Gene: Dnaaf6 (dynein axonemal assembly factor 6) Rattus norvegicus

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Symbol:

Dnaaf6

Name:

dynein axonemal assembly factor 6

RGD ID:

1566312

Description:

Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in flagellated sperm motility; inner dynein arm assembly; and outer dynein arm assembly. Predicted to be located in trans-Golgi network. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 36. Orthologous to human DNAAF6 (dynein axonemal assembly factor 6); INTERACTS WITH bisphenol A; dimethylarsinic acid; Aflatoxin B2 alpha (ortholog).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

dynein assembly factor 6, axonemal; hypothetical protein LOC315915; MGC114520; PIH1 domain containing 3; Pih1d3; similar to hypothetical protein E230019M04; uncharacterized protein LOC315915

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DNAAF6 (dynein axonemal assembly factor 6)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Dnaaf6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dnaaf6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DNAAF6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DNAAF6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dnaaf6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DNAAF6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DNAAF6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dnaaf6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Dnaaf6 (dynein axonemal assembly factor 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	AK6 (adenylate kinase 6)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	DNAAF6 (dynein axonemal assembly factor 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dnaaf6rt (dynein axonemal assembly factor 6, retrotransposed)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dnaaf6 (dynein axonemal assembly factor 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Dnaaf6 (dynein axonemal assembly factor 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pih1d3 (PIH1 domain containing 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5048	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG5048	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dnaaf6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	108,513,002 - 108,564,204 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	108,512,953 - 108,564,972 (+)	Ensembl				GRCr8
mRatBN7.2	X	103,724,419 - 103,775,633 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	103,731,857 - 103,775,629 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	105,856,949 - 105,908,148 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	109,355,691 - 109,406,887 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	106,919,232 - 106,962,757 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	111,389,557 - 111,439,399 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	111,396,995 - 111,439,376 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	53,158,095 - 53,207,937 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	127,813,184 - 127,866,224 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	44,153,230 - 44,203,933 (-)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

primary ciliary dyskinesia (ISO)

primary ciliary dyskinesia 36 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Aflatoxin B2 alpha (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

dimethylarsinic acid (EXP)

GW 4064 (ISO)

ozone (ISO)

sodium arsenite (ISO)

titanium dioxide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axonemal dynein complex assembly (IBA,IEA,ISO)

cilium movement (ISO)

flagellated sperm motility (IBA,ISO)

inner dynein arm assembly (ISO)

outer dynein arm assembly (ISO)

Cellular Component

cytoplasm (IBA,ISO)

Golgi apparatus (ISO)

trans-Golgi network (ISO)

Molecular Function

dynein intermediate chain binding (IBA,ISO)

protein binding (ISO)

protein-folding chaperone binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:28041644	PMID:28176794

Genomics

Comparative Map Data

Dnaaf6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	108,513,002 - 108,564,204 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	108,512,953 - 108,564,972 (+)	Ensembl				GRCr8
mRatBN7.2	X	103,724,419 - 103,775,633 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	103,731,857 - 103,775,629 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	105,856,949 - 105,908,148 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	109,355,691 - 109,406,887 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	106,919,232 - 106,962,757 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	111,389,557 - 111,439,399 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	111,396,995 - 111,439,376 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	53,158,095 - 53,207,937 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	127,813,184 - 127,866,224 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	44,153,230 - 44,203,933 (-)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

DNAAF6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	107,206,611 - 107,244,247 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	107,206,611 - 107,244,247 (+)	Ensembl			hg38	GRCh38
GRCh37	X	106,449,841 - 106,487,477 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	106,336,518 - 106,374,129 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	106,256,006 - 106,293,617	NCBI
Celera	X	106,921,219 - 106,958,830 (+)	NCBI		Celera
Cytogenetic Map	X	q22.3	NCBI
HuRef	X	96,076,351 - 96,114,536 (+)	NCBI		HuRef
CHM1_1	X	106,360,752 - 106,398,365 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	105,643,020 - 105,680,647 (+)	NCBI		T2T-CHM13v2.0

Dnaaf6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	138,963,628 - 139,007,546 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	138,963,628 - 139,007,546 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	140,062,879 - 140,106,797 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	140,062,879 - 140,106,797 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	136,597,418 - 136,641,336 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	135,409,243 - 135,453,161 (+)	NCBI		MGSCv36	mm8
Celera	X	123,325,180 - 123,368,746 (+)	NCBI		Celera
Cytogenetic Map	X	F1	NCBI
cM Map	X	61.35	NCBI

Dnaaf6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955490	8,744,292 - 8,807,766 (-)	Ensembl
ChiLan1.0	NW_004955490	8,760,382 - 8,842,392 (-)	NCBI	ChiLan1.0	ChiLan1.0

DNAAF6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	106,683,474 - 106,721,283 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	106,687,075 - 106,724,884 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	96,300,392 - 96,338,023 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	106,676,738 - 106,714,294 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	106,676,738 - 106,714,294 (+)	Ensembl			panPan2	panpan1.1

DNAAF6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	80,783,424 - 80,825,791 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	80,784,080 - 80,825,809 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	66,902,544 - 66,944,909 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	82,427,098 - 82,469,459 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	82,427,890 - 82,469,477 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	79,889,869 - 79,932,228 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	81,601,411 - 81,643,760 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	81,393,205 - 81,435,158 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dnaaf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	80,154,631 - 80,194,298 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	7,462,398 - 7,494,713 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	7,463,225 - 7,503,322 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DNAAF6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	87,658,360 - 87,696,315 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	87,658,355 - 87,696,318 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	102,030,659 - 102,067,842 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DNAAF6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	95,033,237 - 95,070,766 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	95,041,169 - 95,070,927 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666065	20,116,830 - 20,154,370 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dnaaf6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624803	9,342,963 - 9,391,883 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624803	9,343,012 - 9,391,214 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Dnaaf6
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	91,940,097 - 91,992,093 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Dnaaf6
263 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	97528096	142528096	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	105359969	157758123	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	80434318	125434318	Rat
738029	Stresp2	Stress response QTL 2	3.4	0.0004	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	92979612	117740458	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	105468858	125434318	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	45182909	117740458	Rat
2302047	Pia34	Pristane induced arthritis QTL 34	5.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	19	96916163	141916163	Rat

Markers in Region

RH141078

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	103,727,244 - 103,727,433 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	111,392,383 - 111,392,571	NCBI	Rnor6.0
Rnor_5.0	3	53,204,923 - 53,205,111	UniSTS	Rnor5.0
RGSC_v3.4	X	127,816,010 - 127,816,198	UniSTS	RGSC3.4
Celera	3	44,200,919 - 44,201,107	UniSTS
RH 3.4 Map	10	172.3	UniSTS
Cytogenetic Map	X	q35	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	3	111	7	20	3	14	3	34	17	111	7	63	17	8	8

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC097458	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000087634 ⟹ ENSRNOP00000075079

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	108,512,953 - 108,564,972 (+)	Ensembl
mRatBN7.2 Ensembl	X	103,731,857 - 103,775,629 (+)	Ensembl
Rnor_6.0 Ensembl	X	111,396,995 - 111,439,376 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000121908 ⟹ ENSRNOP00000112177

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	108,520,200 - 108,564,972 (+)	Ensembl

RefSeq Acc Id:

NM_001024890 ⟹ NP_001020061

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	108,513,002 - 108,564,204 (+)	NCBI
mRatBN7.2	X	103,724,419 - 103,775,633 (+)	NCBI
Rnor_6.0	X	111,389,557 - 111,439,399 (+)	NCBI
Rnor_5.0	3	53,158,095 - 53,207,937 (-)	NCBI
RGSC_v3.4	X	127,813,184 - 127,866,224 (+)	RGD
Celera	3	44,153,230 - 44,203,933 (-)	NCBI

Sequence:

show sequence

CGCCTAGGCTTCGACCAGAGCACTGACCAAGCACCTGGGATCCAATTCAGGCCTTCTTCCACTT
TTAGCAAGCACTCTACCCTAGAGCTACACCCCTAGCTATATTTGAATATGGAATCAGAAAATGC
AGAAGCTGAGAACATAGAAACAGGGAAGTTGGAAACAAAGAACGTGGAAGCTAAAAATATGCGA
TTTGAGACACTGTCTTCTGCCTCGGCCCTGCAAGCACTGTCCAATCTCCTGAATCCTGAAGAAG
AGGATGATTTTGATTTTCAACAGGGACAATGCTCATCTACTATTGGAGCCATGGGCCCTGGGAA
TATTGGACCACCTAAAGCAAAAGAGTCCAAAGCCATTCCTGAACCCAGGAGTGATGAAAGTGAG
AACATCTGGAATCCAGAAGAGGTTCCAGAAGGAGCAGAGCATGATGATATATGGGATGCTCGAG
AAGTCCCAGATTATGAGATTGTGTTCCAACAAACGGTGGGAACTGAAGACGTGTACCTAGGATT
AACAAGAAAGGATCCTTCAACAGCATGCTGCCAGGAGCTGGTGGTGAAAATTAAACTGCCCGAT
ACAAACCCTTCTGAAATTCAAATTGACATCCAAGAAATGCTCCTTGATCTTCGTACTCCTAAAA
AGAAGCTGCTAGTGAACCTTCCCCAGCCTGTGGAACATAACAGTGCTAAAGCGTCCTATATCTG
GGAAGCTGAAACACTTGAAGTCAGGATGACCCTCCAAAGGGATTTGGATTTTAATATTTCCTGA
AACTGGATGAATAAGAAGAGATAGAAAAATTCAGGACAATGAAAACTTTTTTTTACCTTTTAAT
ACTGGTTGTTTATGTTCTCTTTTTCCCACTGACATAGTTTAGAAAGGTTCAGATTTTTAGTGAT
GTTTTGATTATATACAGTCAAATCTATTACTGTTAGGAAATATGGTTGTTTCATACGATAAGGT
GCTATTCCATTTTTATAGTGAGAGCTGAATAAAATATTTTCAGGTTAACCATCTAGATTGCTAC
ATGGTCAATTGCACAGCAGAGCTATGACCATAAAATAAGTGATTCATTTAAATCAGCAGTCTGA
GGATCTTAAGCTAATGAATTTCACTACCATACAATCTGCTACATAGGGATTTGTCATTATTATC
ACCAGAAAAATTCATTTGGCTGCTTTTCCATTGATTTTATCAAATGATTTAGGATGTTTTCAAT
CTAGGTCCTCCATATTGTTCTGGAACATACAAGTAAGAAAGGACTATAAATAATTTGTTGTGTC
TTGTGAGACACATGTTTACTTGAAAAAGCAATACTTATAGATGTATATGTAGATTCATTTTTCT
CTCATTTTTATCTTCCTAATTGGACATTCTTACTTTTATAAATTATCCCAATGTTCCTCACATT
TTCTGTACTATTGAATGAGTTTGTTTCATTACTGTTTATTAAAAACTTACATTTTATCAGTGTA
ACTTGACATCATTGTATAACTGTGAGATTGACTGGGAGTAAATTTTGAAAAAAGAGATAAAGAA
CTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001020061	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97458	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075079
	ENSRNOP00000075079.2
	ENSRNOP00000112177.1

RefSeq Acc Id:

NP_001020061 ⟸ NM_001024890

- UniProtKB:

Q4V8B6 (UniProtKB/TrEMBL), A0A0G2K9P7 (UniProtKB/TrEMBL), A6HLS2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MESENAEAENIETGKLETKNVEAKNMRFETLSSASALQALSNLLNPEEEDDFDFQQGQCSSTIG
AMGPGNIGPPKAKESKAIPEPRSDESENIWNPEEVPEGAEHDDIWDAREVPDYEIVFQQTVGTE
DVYLGLTRKDPSTACCQELVVKIKLPDTNPSEIQIDIQEMLLDLRTPKKKLLVNLPQPVEHNSA
KASYIWEAETLEVRMTLQRDLDFNIS

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Ensembl Acc Id:

ENSRNOP00000075079 ⟸ ENSRNOT00000087634

Ensembl Acc Id:

ENSRNOP00000112177 ⟸ ENSRNOT00000121908

Protein Domains

PIH1D1/2/3 CS-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K9P7-F1-model_v2	AlphaFold	A0A0G2K9P7	1-216	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1566312	AgrOrtholog
BioCyc Gene	G2FUF-1547	BioCyc
Ensembl Genes	ENSRNOG00000054900	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000087634	ENTREZGENE
	ENSRNOT00000087634.3	UniProtKB/TrEMBL
	ENSRNOT00000121908.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7457221	IMAGE-MGC_LOAD
InterPro	PIH1D1/2/3_CS-like	UniProtKB/TrEMBL
	PIH1D3	UniProtKB/TrEMBL
KEGG Report	rno:315915	UniProtKB/TrEMBL
MGC_CLONE	MGC:114520	IMAGE-MGC_LOAD
NCBI Gene	315915	ENTREZGENE
PANTHER	DYNEIN AXONEMAL ASSEMBLY FACTOR 6	UniProtKB/TrEMBL
	PTHR21083	UniProtKB/TrEMBL
Pfam	PIH1_CS	UniProtKB/TrEMBL
PhenoGen	Dnaaf6	PhenoGen
RatGTEx	ENSRNOG00000054900	RatGTEx
UniProt	A0A0G2K9P7	ENTREZGENE
	A0ABK0M234_RAT	UniProtKB/TrEMBL
	A6HLS2	ENTREZGENE, UniProtKB/TrEMBL
	Q4V8B6	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A0G2K9P7	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-01-10	Dnaaf6	dynein axonemal assembly factor 6	Pih1d3	PIH1 domain containing 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-05	Pih1d3	PIH1 domain containing 3	MGC114520	similar to hypothetical protein E230019M04	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	MGC114520	similar to hypothetical protein E230019M04			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM