Thsd4 (thrombospondin type 1 domain containing 4) - Rat Genome Database

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Gene: Thsd4 (thrombospondin type 1 domain containing 4) Rattus norvegicus
Analyze
Symbol: Thsd4
Name: thrombospondin type 1 domain containing 4
RGD ID: 1566296
Description: Predicted to enable hydrolase activity. Predicted to be involved in microfibril assembly. Predicted to act upstream of or within elastic fiber assembly. Predicted to be located in microfibril. Human ortholog(s) of this gene implicated in asthma and thoracic aortic aneurysm. Orthologous to human THSD4 (thrombospondin type 1 domain containing 4); INTERACTS WITH atrazine; bisphenol A; methoxychlor.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07070307.1; LOC315728; RGD1566296; similar to RIKEN cDNA B230114P05; thrombospondin type-1 domain-containing protein 4; thrombospondin, type I, domain containing 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8869,280,397 - 69,880,144 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl869,284,646 - 69,917,342 (-)EnsemblGRCr8
mRatBN7.2860,384,636 - 60,984,419 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl860,386,875 - 61,024,995 (-)EnsemblmRatBN7.2
Rnor_6.0864,811,940 - 65,413,498 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl864,817,191 - 65,003,296 (-)Ensemblrn6Rnor6.0
Rnor_5.0864,569,306 - 65,166,353 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4863,925,951 - 64,415,899 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera859,826,443 - 60,422,430 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
extracellular matrix  (IEA,ISO)
microfibril  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Genome-wide interaction study reveals age-dependent determinants of responsiveness to inhaled corticosteroids in individuals with asthma. Dahlin A, etal., PLoS One. 2020 Mar 2;15(3):e0229241. doi: 10.1371/journal.pone.0229241. eCollection 2020.
2. Pathogenic variants in THSD4, encoding the ADAMTS-like 6 protein, predispose to inherited thoracic aortic aneurysm. Elbitar S, etal., Genet Med. 2021 Jan;23(1):111-122. doi: 10.1038/s41436-020-00947-4. Epub 2020 Aug 28.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19199708   PMID:19940141   PMID:23979707  


Genomics

Comparative Map Data
Thsd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8869,280,397 - 69,880,144 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl869,284,646 - 69,917,342 (-)EnsemblGRCr8
mRatBN7.2860,384,636 - 60,984,419 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl860,386,875 - 61,024,995 (-)EnsemblmRatBN7.2
Rnor_6.0864,811,940 - 65,413,498 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl864,817,191 - 65,003,296 (-)Ensemblrn6Rnor6.0
Rnor_5.0864,569,306 - 65,166,353 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4863,925,951 - 64,415,899 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera859,826,443 - 60,422,430 (-)NCBICelera
Cytogenetic Map8q24NCBI
THSD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381571,096,894 - 71,783,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1571,096,952 - 71,783,383 (+)Ensemblhg38GRCh38
GRCh371571,389,233 - 72,075,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361569,220,842 - 69,862,776 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1548,324,642 - 48,962,070 (+)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1548,268,554 - 48,906,012 (+)NCBIHuRef
CHM1_11571,551,994 - 72,193,852 (+)NCBICHM1_1
T2T-CHM13v2.01568,920,176 - 69,602,307 (+)NCBIT2T-CHM13v2.0
Thsd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39959,874,214 - 60,429,394 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl959,874,214 - 60,429,329 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38959,966,931 - 60,522,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl959,966,931 - 60,522,046 (-)Ensemblmm10GRCm38
MGSCv37959,814,738 - 60,358,842 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36959,767,725 - 59,939,141 (-)NCBIMGSCv36mm8
Celera957,195,098 - 57,735,471 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.38NCBI
Thsd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554505,301,765 - 5,479,638 (-)Ensembl
ChiLan1.0NW_0049554505,296,670 - 5,827,252 (-)NCBIChiLan1.0ChiLan1.0
THSD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21660,381,474 - 61,046,548 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11564,545,397 - 65,210,704 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01550,067,560 - 50,732,761 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11568,859,738 - 69,497,610 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1568,859,819 - 69,491,696 (+)EnsemblpanPan2panpan1.1
THSD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13035,156,926 - 35,358,673 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3035,156,981 - 35,353,767 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3034,726,043 - 35,042,345 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
Dog10K_Boxer_Tasha3035,091,914 - 35,293,801 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03034,990,940 - 35,563,193 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3035,358,882 - 35,558,722 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13034,946,198 - 35,514,090 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03035,339,869 - 35,542,129 (+)NCBIUNSW_CanFamBas_1.0
UNSW_CanFamBas_1.03034,974,569 - 35,290,502 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03035,230,015 - 35,796,275 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Thsd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640112,781,079 - 113,364,996 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647130,654,136 - 31,207,266 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647131,002,241 - 31,213,057 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THSD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1168,751,582 - 169,323,977 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11168,751,403 - 169,328,559 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21187,773,138 - 188,056,930 (+)NCBISscrofa10.2Sscrofa10.2susScr3
THSD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12611,677,332 - 12,207,092 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2611,683,231 - 11,912,098 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666048129,220,676 - 129,891,992 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Thsd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247812,217,684 - 2,411,072 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247812,217,668 - 2,793,867 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Thsd4
3778 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:183
Count of miRNA genes:83
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000073074, ENSRNOT00000074433, ENSRNOT00000075158
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85899169791341052Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)84754141992541419Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85899169791341052Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85899169791341052Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat

Markers in Region
D8Got93  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2860,816,901 - 60,817,101 (+)MAPPERmRatBN7.2
Rnor_6.0865,243,025 - 65,243,224NCBIRnor6.0
Rnor_5.0864,997,686 - 64,997,885UniSTSRnor5.0
RGSC_v3.4864,274,180 - 64,274,379UniSTSRGSC3.4
RGSC_v3.4864,274,179 - 64,274,379RGDRGSC3.4
Celera860,253,847 - 60,254,046UniSTS
RGSC_v3.1864,293,234 - 64,293,433RGD
RH 3.4 Map8717.0UniSTS
RH 3.4 Map8717.0RGD
RH 2.0 Map8564.0RGD
Cytogenetic Map8q24UniSTS
D8Got92  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2860,816,185 - 60,816,443 (+)MAPPERmRatBN7.2
Rnor_6.0865,242,309 - 65,242,566NCBIRnor6.0
Rnor_5.0864,996,970 - 64,997,227UniSTSRnor5.0
RGSC_v3.4864,273,464 - 64,273,721UniSTSRGSC3.4
RGSC_v3.4864,273,463 - 64,273,721RGDRGSC3.4
Celera860,253,131 - 60,253,388UniSTS
RGSC_v3.1864,292,518 - 64,292,775RGD
RH 3.4 Map8727.2UniSTS
RH 3.4 Map8727.2RGD
RH 2.0 Map8574.4RGD
Cytogenetic Map8q24UniSTS
D8Got90  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8869,808,362 - 69,808,524 (+)Marker Load Pipeline
mRatBN7.2860,912,644 - 60,912,806 (+)MAPPERmRatBN7.2
Rnor_6.0865,341,892 - 65,342,053NCBIRnor6.0
Rnor_5.0865,094,769 - 65,094,930UniSTSRnor5.0
RGSC_v3.4864,372,013 - 64,372,174UniSTSRGSC3.4
RGSC_v3.4864,372,012 - 64,372,174RGDRGSC3.4
Celera860,347,998 - 60,348,159UniSTS
RGSC_v3.1864,391,066 - 64,391,228RGD
Cytogenetic Map8q24UniSTS
D8Got91  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8869,749,489 - 69,749,755 (+)Marker Load Pipeline
mRatBN7.2860,853,774 - 60,854,042 (+)MAPPERmRatBN7.2
Rnor_6.0865,280,381 - 65,280,650NCBIRnor6.0
Rnor_5.0865,035,042 - 65,035,311UniSTSRnor5.0
RGSC_v3.4864,312,661 - 64,312,930UniSTSRGSC3.4
RGSC_v3.4864,312,660 - 64,312,930RGDRGSC3.4
RGSC_v3.4864,311,859 - 64,312,930UniSTSRGSC3.4
Celera860,290,087 - 60,290,352UniSTS
RGSC_v3.1864,331,715 - 64,331,984RGD
RH 3.4 Map8727.2RGD
RH 3.4 Map8727.2UniSTS
Cytogenetic Map8q24UniSTS
AU046829  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8869,573,847 - 69,574,092 (+)Marker Load Pipeline
mRatBN7.2860,678,123 - 60,678,370 (+)MAPPERmRatBN7.2
Rnor_6.0865,103,915 - 65,104,161NCBIRnor6.0
Rnor_5.0864,858,554 - 64,858,800UniSTSRnor5.0
RGSC_v3.4864,133,632 - 64,133,876UniSTSRGSC3.4
Celera860,115,172 - 60,115,392UniSTS
Cytogenetic Map8q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 11 64 161 74 70 47 44 47 6 287 140 11 140 78 89 23 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000076201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl864,844,423 - 65,003,296 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl869,284,646 - 69,917,342 (-)Ensembl
mRatBN7.2 Ensembl860,386,875 - 61,024,995 (-)Ensembl
Rnor_6.0 Ensembl864,817,191 - 64,913,684 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085526   ⟹   ENSRNOP00000085220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl869,284,646 - 69,472,841 (-)Ensembl
mRatBN7.2 Ensembl860,386,875 - 60,577,093 (-)Ensembl
RefSeq Acc Id: XM_039082429   ⟹   XP_038938357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,280,397 - 69,880,144 (-)NCBI
mRatBN7.2860,384,636 - 60,984,419 (-)NCBI
RefSeq Acc Id: XM_039082430   ⟹   XP_038938358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,280,397 - 69,477,879 (-)NCBI
mRatBN7.2860,384,636 - 60,578,920 (-)NCBI
RefSeq Acc Id: XP_038938357   ⟸   XM_039082429
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938358   ⟸   XM_039082430
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000085220   ⟸   ENSRNOT00000085526
Protein Domains
PLAC

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566296 AgrOrtholog
BioCyc Gene G2FUF-30219 BioCyc
Ensembl Genes ENSRNOG00000051221 Ensembl
  ENSRNOG00000053753 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081697 ENTREZGENE
  ENSRNOT00000081697.3 UniProtKB/TrEMBL
  ENSRNOT00000085526 ENTREZGENE
  ENSRNOT00000085526.3 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/TrEMBL
InterPro ADAMTS_ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_CR_3 UniProtKB/TrEMBL
  ADAMTS_spacer1 UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene 315728 ENTREZGENE
PANTHER ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/TrEMBL
  THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
Pfam ADAM_CR_3 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PhenoGen Thsd4 PhenoGen
PROSITE PLAC UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051221 RatGTEx
  ENSRNOG00000053753 RatGTEx
SMART TSP1 UniProtKB/TrEMBL
Superfamily-SCOP SSF82895 UniProtKB/TrEMBL
UniProt A0A8I6A1T6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN95 ENTREZGENE, UniProtKB/TrEMBL
  A6J545 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Thsd4  thrombospondin type 1 domain containing 4  AABR07070307.1    Data merged from RGD:15008157 737654 PROVISIONAL
2019-11-08 AABR07070307.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2015-12-09 Thsd4  thrombospondin type 1 domain containing 4  Thsd4  thrombospondin, type I, domain containing 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-12 Thsd4  thrombospondin, type I, domain containing 4  RGD1566296  similar to RIKEN cDNA B230114P05  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1566296  similar to RIKEN cDNA B230114P05   RGD1566296_predicted  similar to RIKEN cDNA B230114P05 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1566296_predicted  similar to RIKEN cDNA B230114P05 (predicted)  LOC315728  similar to RIKEN cDNA B230114P05  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC315728  similar to RIKEN cDNA B230114P05      Symbol and Name status set to provisional 70820 PROVISIONAL