Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Aldh16a1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of ALDH16A1 mRNA | CTD | PMID:22206623 | Aldh16a1 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ALDH16A1 protein | CTD | PMID:32145629 | Aldh16a1 | Rat | 17beta-estradiol | decreases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ALDH16A1 mRNA | CTD | PMID:31614463 | Aldh16a1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Aldh16a1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of ALDH16A1 mRNA | CTD | PMID:16214954 | Aldh16a1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ALDH16A1 mRNA | CTD | PMID:33387578 | Aldh16a1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ALDH16A1 mRNA | CTD | PMID:18796159|PMID:26290441 | Aldh16a1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ALDH16A1 mRNA | CTD | PMID:20702594|PMID:21570461|PMID:26377647 | Aldh16a1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ALDH16A1 mRNA | CTD | PMID:22574217 | Aldh16a1 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | 2,3,7,8-tetrachlorodibenzofuran affects the expression of ALDH16A1 mRNA | CTD | PMID:20702594 | Aldh16a1 | Rat | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin analog results in decreased expression of ALDH16A1 protein | CTD | PMID:26597043 | Aldh16a1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Aldh16a1 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of ALDH16A1 mRNA | CTD | PMID:18648102 | Aldh16a1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Aldh16a1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of ALDH16A1 mRNA | CTD | PMID:39298647 | Aldh16a1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ALDH16A1 mRNA | CTD | PMID:30047161 | Aldh16a1 | Rat | 7,9-dihydro-1H-purine-2,6,8(3H)-trione | affects abundance | ISO | ALDH16A1 (Homo sapiens) | 6480464 | ALDH16A1 gene SNP affects the abundance of Uric Acid | CTD | PMID:21983786 | Aldh16a1 | Rat | acrolein | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268|PMID:32845096 | Aldh16a1 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of ALDH16A1 mRNA | CTD | PMID:28959563 | Aldh16a1 | Rat | alpha-pinene | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Aldh16a1 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of ALDH16A1 mRNA | CTD | PMID:30047161 | Aldh16a1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ALDH16A1 mRNA | CTD | PMID:16483693 | Aldh16a1 | Rat | aristolochic acid A | increases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of ALDH16A1 mRNA | CTD | PMID:33212167 | Aldh16a1 | Rat | atrazine | decreases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of ALDH16A1 mRNA | CTD | PMID:22378314 | Aldh16a1 | Rat | benzo[a]pyrene | decreases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ALDH16A1 mRNA | CTD | PMID:20127859 | Aldh16a1 | Rat | benzo[a]pyrene | decreases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ALDH16A1 mRNA | CTD | PMID:20106945 | Aldh16a1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ALDH16A1 mRNA | CTD | PMID:25181051 | Aldh16a1 | Rat | bisphenol A | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ALDH16A1 gene | CTD | PMID:31601247 | Aldh16a1 | Rat | bisphenol A | increases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ALDH16A1 mRNA | CTD | PMID:33221593 | Aldh16a1 | Rat | bisphenol A | decreases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ALDH16A1 mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:33670352|PMID:34186270 | Aldh16a1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ALDH16A1 mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:30816183|PMID:32145629|PMID:32528016|PMID:34947998 | Aldh16a1 | Rat | bisphenol F | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of ALDH16A1 gene | CTD | PMID:31601247 | Aldh16a1 | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of ALDH16A1 mRNA | CTD | PMID:19167457 | Aldh16a1 | Rat | cisplatin | decreases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ALDH16A1 mRNA | CTD | PMID:27392435 | Aldh16a1 | Rat | coumestrol | increases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of ALDH16A1 mRNA | CTD | PMID:19167446 | Aldh16a1 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of ALDH16A1 mRNA | CTD | PMID:26577399 | Aldh16a1 | Rat | dexamethasone | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Aldh16a1 | Rat | Dibutyl phosphate | affects expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ALDH16A1 mRNA | CTD | PMID:37042841 | Aldh16a1 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ALDH16A1 mRNA | CTD | PMID:21266533 | Aldh16a1 | Rat | enzyme inhibitor | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Aldh16a1 | Rat | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of ALDH16A1 protein | CTD | PMID:19609968 | Aldh16a1 | Rat | fulvestrant | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ALDH16A1 gene; [bisphenol F co-treated more ... | CTD | PMID:31601247 | Aldh16a1 | Rat | furan | decreases methylation | EXP | | 6480464 | furan results in decreased methylation of ALDH16A1 gene | CTD | PMID:22079235 | Aldh16a1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ALDH16A1 mRNA | CTD | PMID:33387578 | Aldh16a1 | Rat | glyphosate | decreases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of ALDH16A1 protein | CTD | PMID:37208198 | Aldh16a1 | Rat | GSK-J4 | decreases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | GSK-J4 results in decreased expression of ALDH16A1 mRNA | CTD | PMID:29301935 | Aldh16a1 | Rat | indometacin | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Aldh16a1 | Rat | ivermectin | decreases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ALDH16A1 protein | CTD | PMID:32959892 | Aldh16a1 | Rat | lead(0) | affects expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Lead affects the expression of ALDH16A1 mRNA | CTD | PMID:28903495 | Aldh16a1 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of ALDH16A1 mRNA | CTD | PMID:30047161 | Aldh16a1 | Rat | ozone | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268|PMID:32845096 | Aldh16a1 | Rat | pirinixic acid | decreases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ALDH16A1 mRNA | CTD | PMID:23811191 | Aldh16a1 | Rat | SB 431542 | multiple interactions | ISO | ALDH16A1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of ALDH16A1 more ... | CTD | PMID:37664457 | Aldh16a1 | Rat | sodium arsenate | increases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | sodium arsenate results in increased expression of ALDH16A1 protein | CTD | PMID:38348393 | Aldh16a1 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of ALDH16A1 mRNA | CTD | PMID:19281266 | Aldh16a1 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of ALDH16A1 mRNA | CTD | PMID:30047161 | Aldh16a1 | Rat | temozolomide | increases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of ALDH16A1 mRNA | CTD | PMID:31758290 | Aldh16a1 | Rat | titanium dioxide | increases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ALDH16A1 mRNA | CTD | PMID:29264374 | Aldh16a1 | Rat | titanium dioxide | decreases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ALDH16A1 mRNA | CTD | PMID:35295148 | Aldh16a1 | Rat | trovafloxacin | decreases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of ALDH16A1 mRNA | CTD | PMID:35537566 | Aldh16a1 | Rat | valproic acid | increases methylation | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ALDH16A1 gene | CTD | PMID:29154799 | Aldh16a1 | Rat | valproic acid | decreases expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ALDH16A1 mRNA | CTD | PMID:29154799 | Aldh16a1 | Rat | valproic acid | affects expression | ISO | ALDH16A1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ALDH16A1 mRNA | CTD | PMID:25979313 | Aldh16a1 | Rat | vancomycin | increases expression | ISO | Aldh16a1 (Mus musculus) | 6480464 | Vancomycin results in increased expression of ALDH16A1 mRNA | CTD | PMID:18930951 | Aldh16a1 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of ALDH16A1 mRNA | CTD | PMID:23034163 | | 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