Symbol:
Ttll7
Name:
tubulin tyrosine ligase like 7
RGD ID:
1566117
Description:
Predicted to enable alpha-tubulin binding activity; beta-tubulin binding activity; and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to be located in 9+0 non-motile cilium. Predicted to be active in ciliary basal body. Orthologous to human TTLL7 (tubulin tyrosine ligase like 7); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC108350133; LOC310982; RGD1566117; similar to hypothetical protein FLJ23033; tubulin polyglutamylase TTLL7; tubulin polyglutamylase TTLL7-like; tubulin tyrosine ligase-like family, member 7
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
TTLL7 (tubulin tyrosine ligase like 7)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Ttll7 (tubulin tyrosine ligase-like family, member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ttll7 (tubulin tyrosine ligase like 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TTLL7 (tubulin tyrosine ligase like 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TTLL7 (tubulin tyrosine ligase like 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ttll7 (tubulin tyrosine ligase like 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TTLL7 (tubulin tyrosine ligase like 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
TTLL7 (tubulin tyrosine ligase like 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ttll7 (tubulin tyrosine ligase like 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Ttll7 (tubulin tyrosine ligase like 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
TKT (transketolase)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
TTLL7 (tubulin tyrosine ligase like 7)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Ttll7 (tubulin tyrosine ligase-like family, member 7)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ttll7 (tubulin tyrosine ligase-like family, member 7)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ttll7
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 238,425,786 - 238,549,296 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 2 238,426,076 - 238,545,960 (+) Ensembl GRCr8 mRatBN7.2 2 235,765,786 - 235,889,047 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 235,765,835 - 235,885,047 (+) Ensembl mRatBN7.2 Rnor_6.0 2 252,779,741 - 252,854,746 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 252,771,017 - 252,850,495 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 2 271,259,539 - 271,381,625 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 2 245,076,731 - 245,194,146 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 2 227,740,142 - 227,862,013 (+) NCBI Celera Cytogenetic Map 2 q44 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Ttll7 Rat (1->4)-beta-D-glucan multiple interactions ISO Ttll7 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TTLL7 mRNA CTD PMID:36331819 Ttll7 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Ttll7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ttll7 Rat 17beta-estradiol multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of TTLL7 mRNA CTD PMID:30165855 Ttll7 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Ttll7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ttll7 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Ttll7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ttll7 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Ttll7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ttll7 Rat 3,4-methylenedioxymethamphetamine increases expression ISO Ttll7 (Mus musculus) 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of TTLL7 mRNA CTD PMID:20188158 Ttll7 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of TTLL7 mRNA CTD PMID:24780913 Ttll7 Rat aflatoxin B1 decreases methylation ISO TTLL7 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of TTLL7 gene CTD PMID:27153756 Ttll7 Rat all-trans-retinoic acid multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of TTLL7 mRNA CTD PMID:15894607 Ttll7 Rat all-trans-retinoic acid increases expression ISO TTLL7 (Homo sapiens) 6480464 Tretinoin results in increased expression of TTLL7 mRNA CTD PMID:15894607 Ttll7 Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of TTLL7 mRNA CTD PMID:30779732 Ttll7 Rat antirheumatic drug increases expression ISO TTLL7 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of TTLL7 mRNA CTD PMID:24449571 Ttll7 Rat aristolochic acid A decreases expression ISO TTLL7 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of TTLL7 mRNA CTD PMID:33212167 Ttll7 Rat arsenous acid multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of TTLL7 mRNA CTD PMID:15894607 Ttll7 Rat benzo[a]pyrene affects methylation ISO TTLL7 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of TTLL7 5' UTR CTD PMID:27901495 Ttll7 Rat benzo[a]pyrene increases methylation ISO TTLL7 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of TTLL7 promoter CTD PMID:27901495 Ttll7 Rat benzo[b]fluoranthene decreases expression ISO Ttll7 (Mus musculus) 6480464 benzo(b)fluoranthene results in decreased expression of TTLL7 mRNA CTD PMID:26377693 Ttll7 Rat beta-lapachone decreases expression ISO TTLL7 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of TTLL7 mRNA CTD PMID:38218311 Ttll7 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TTLL7 mRNA CTD PMID:25181051 Ttll7 Rat Butylbenzyl phthalate increases methylation ISO Ttll7 (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of TTLL7 intron CTD PMID:28392331 Ttll7 Rat C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of TTLL7 mRNA CTD PMID:19167457 Ttll7 Rat carbon nanotube increases expression ISO Ttll7 (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of TTLL7 mRNA; Nanotubes, Carbon results in increased more ... CTD PMID:25554681 Ttll7 Rat CGP 52608 multiple interactions ISO TTLL7 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to TTLL7 gene] CTD PMID:28238834 Ttll7 Rat chlordecone increases expression ISO Ttll7 (Mus musculus) 6480464 Chlordecone results in increased expression of TTLL7 mRNA CTD PMID:33711761 Ttll7 Rat chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of TTLL7 mRNA CTD PMID:23125180 Ttll7 Rat chlorpyrifos decreases expression ISO Ttll7 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of TTLL7 mRNA CTD PMID:37019170 Ttll7 Rat chrysene increases expression ISO Ttll7 (Mus musculus) 6480464 chrysene results in increased expression of TTLL7 mRNA CTD PMID:26377693 Ttll7 Rat cisplatin multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of TTLL7 mRNA CTD PMID:27392435 Ttll7 Rat cobalt atom multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which results in decreased expression of TTLL7 mRNA CTD PMID:20105288 Ttll7 Rat cobalt dichloride increases expression ISO TTLL7 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of TTLL7 mRNA CTD PMID:20105288 Ttll7 Rat copper atom multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of TTLL7 mRNA CTD PMID:20971185 Ttll7 Rat copper(0) multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of TTLL7 mRNA CTD PMID:20971185 Ttll7 Rat crocidolite asbestos decreases expression ISO Ttll7 (Mus musculus) 6480464 Asbestos, Crocidolite results in decreased expression of TTLL7 mRNA CTD PMID:29279043 Ttll7 Rat cyclosporin A increases expression ISO TTLL7 (Homo sapiens) 6480464 Cyclosporine results in increased expression of TTLL7 mRNA CTD PMID:20106945|PMID:27989131 Ttll7 Rat diarsenic trioxide multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of TTLL7 mRNA CTD PMID:15894607 Ttll7 Rat dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression more ... CTD PMID:33729688 Ttll7 Rat doxorubicin increases expression ISO Ttll7 (Mus musculus) 6480464 Doxorubicin results in increased expression of TTLL7 mRNA CTD PMID:25896364|PMID:39631538 Ttll7 Rat doxorubicin decreases expression ISO TTLL7 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of TTLL7 mRNA CTD PMID:29803840 Ttll7 Rat ethanol multiple interactions ISO Ttll7 (Mus musculus) 6480464 Ethanol affects the expression of and affects the splicing of TTLL7 mRNA CTD PMID:30319688 Ttll7 Rat formaldehyde increases expression ISO TTLL7 (Homo sapiens) 6480464 Formaldehyde results in increased expression of TTLL7 mRNA CTD PMID:27905399 Ttll7 Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of TTLL7 mRNA CTD PMID:33387578 Ttll7 Rat isoprenaline increases expression ISO Ttll7 (Mus musculus) 6480464 Isoproterenol results in increased expression of TTLL7 mRNA CTD PMID:20003209 Ttll7 Rat ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of TTLL7 mRNA CTD PMID:20080153 Ttll7 Rat lipopolysaccharide multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TTLL7 mRNA CTD PMID:35811015 Ttll7 Rat methylmercury chloride decreases expression ISO TTLL7 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of TTLL7 mRNA CTD PMID:28001369 Ttll7 Rat nickel atom decreases expression ISO TTLL7 (Homo sapiens) 6480464 Nickel results in decreased expression of TTLL7 mRNA CTD PMID:24768652|PMID:25583101 Ttll7 Rat nickel sulfate decreases expression ISO TTLL7 (Homo sapiens) 6480464 nickel sulfate results in decreased expression of TTLL7 mRNA CTD PMID:22714537 Ttll7 Rat okadaic acid increases expression ISO TTLL7 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of TTLL7 mRNA CTD PMID:38832940 Ttll7 Rat paracetamol increases expression ISO TTLL7 (Homo sapiens) 6480464 Acetaminophen results in increased expression of TTLL7 mRNA CTD PMID:21420995 Ttll7 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of TTLL7 mRNA CTD PMID:33387578 Ttll7 Rat PCB138 multiple interactions ISO Ttll7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ttll7 Rat perfluorooctane-1-sulfonic acid decreases expression ISO TTLL7 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of TTLL7 mRNA CTD PMID:27153767 Ttll7 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Ttll7 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TTLL7 mRNA CTD PMID:36331819 Ttll7 Rat pirinixic acid multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Ttll7 Rat potassium chromate decreases expression ISO TTLL7 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of TTLL7 mRNA CTD PMID:22714537 Ttll7 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TTLL7 mRNA CTD PMID:35811015 Ttll7 Rat sodium arsenite increases expression ISO TTLL7 (Homo sapiens) 6480464 sodium arsenite results in increased expression of TTLL7 mRNA CTD PMID:38568856 Ttll7 Rat sulforaphane decreases expression ISO Ttll7 (Mus musculus) 6480464 sulforaphane results in decreased expression of TTLL7 mRNA CTD PMID:30529165 Ttll7 Rat temozolomide increases expression ISO TTLL7 (Homo sapiens) 6480464 Temozolomide results in increased expression of TTLL7 mRNA CTD PMID:31758290 Ttll7 Rat testosterone increases expression ISO Ttll7 (Mus musculus) 6480464 Testosterone results in increased expression of TTLL7 mRNA CTD PMID:20403060 Ttll7 Rat testosterone decreases expression ISO TTLL7 (Homo sapiens) 6480464 Testosterone results in decreased expression of TTLL7 mRNA CTD PMID:33359661 Ttll7 Rat thiram increases expression ISO TTLL7 (Homo sapiens) 6480464 Thiram results in increased expression of TTLL7 mRNA CTD PMID:38568856 Ttll7 Rat titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of TTLL7 mRNA CTD PMID:30012374 Ttll7 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of TTLL7 mRNA CTD PMID:33387578 Ttll7 Rat trichostatin A affects expression ISO TTLL7 (Homo sapiens) 6480464 trichostatin A affects the expression of TTLL7 mRNA CTD PMID:28542535 Ttll7 Rat triphenyl phosphate affects expression ISO TTLL7 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of TTLL7 mRNA CTD PMID:37042841 Ttll7 Rat Tungsten carbide multiple interactions ISO TTLL7 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which results in decreased expression of TTLL7 mRNA CTD PMID:20105288 Ttll7 Rat Tungsten carbide decreases expression ISO TTLL7 (Homo sapiens) 6480464 tungsten carbide results in decreased expression of TTLL7 mRNA CTD PMID:20105288 Ttll7 Rat valproic acid affects expression ISO TTLL7 (Homo sapiens) 6480464 Valproic Acid affects the expression of TTLL7 mRNA CTD PMID:25979313 Ttll7 Rat valproic acid increases expression ISO TTLL7 (Homo sapiens) 6480464 Valproic Acid results in increased expression of TTLL7 mRNA CTD PMID:23179753|PMID:27188386|PMID:29154799 Ttll7 Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of TTLL7 mRNA CTD PMID:19015723