Rnf208 (ring finger protein 208) - Rat Genome Database

Name: Rnf208
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Rnf208 (ring finger protein 208) Rattus norvegicus

Analyze

Symbol:

Rnf208

Name:

ring finger protein 208

RGD ID:

1565957

Description:

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein autoubiquitination. Predicted to be located in cytosol and nucleoplasm. Orthologous to human RNF208 (ring finger protein 208); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC499748; RGD1565957; similar to RIKEN cDNA 1110061N23

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF208 (ring finger protein 208)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Rnf208 (ring finger protein 208)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnf208 (ring finger protein 208)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF208 (ring finger protein 208)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNF208 (ring finger protein 208)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf208 (ring finger protein 208)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF208 (ring finger protein 208)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RNF208 (ring finger protein 208)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf208 (ring finger protein 208)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Rnf208 (ring finger protein 208)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RNF208 (ring finger protein 208)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-106l3.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	28,455,836 - 28,457,879 (+)	NCBI		GRCr8
mRatBN7.2	3	8,057,808 - 8,059,721 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	8,043,685 - 8,059,844 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	11,163,109 - 11,164,433 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	19,749,339 - 19,750,663 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	17,939,182 - 17,940,506 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	2,462,466 - 2,463,790 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	2,462,466 - 2,463,790 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	2,443,879 - 2,445,203 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	3,408,497 - 3,409,821 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	2,884,946 - 2,886,270 (+)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Adams-Oliver Syndrome 5 (ISO)

autosomal dominant intellectual developmental disorder 8 (ISO)

developmental and epileptic encephalopathy 14 (ISO)

epilepsy (ISO)

genetic disease (ISO)

Joubert syndrome 1 (ISO)

Kleefstra syndrome 1 (ISO)

primary coenzyme Q10 deficiency 7 (ISO)

Rafiq syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

bisphenol F (EXP)

cadmium atom (ISO)

caffeine (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

clofibrate (ISO)

dicrotophos (ISO)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

hydroquinone O-beta-D-glucopyranoside (ISO)

L-methionine (ISO)

lead(0) (ISO)

maneb (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

paraquat (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

sodium fluoride (ISO)

testosterone (ISO)

tremolite asbestos (ISO)

trichloroethene (EXP)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein autoubiquitination (ISO)

protein ubiquitination (IBA)

Cellular Component

cytosol (ISO)

nucleoplasm (ISO)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

ubiquitin protein ligase activity (IBA)

ubiquitin-protein transferase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:24105792

Genomics

Comparative Map Data

Rnf208
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	28,455,836 - 28,457,879 (+)	NCBI		GRCr8
mRatBN7.2	3	8,057,808 - 8,059,721 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	8,043,685 - 8,059,844 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	11,163,109 - 11,164,433 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	19,749,339 - 19,750,663 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	17,939,182 - 17,940,506 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	2,462,466 - 2,463,790 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	2,462,466 - 2,463,790 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	2,443,879 - 2,445,203 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	3,408,497 - 3,409,821 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	2,884,946 - 2,886,270 (+)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI

RNF208
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	137,220,259 - 137,223,408 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	137,220,247 - 137,222,240 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	140,114,711 - 140,117,860 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	139,234,528 - 139,235,596 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Cytogenetic Map	9	q34.3	NCBI
HuRef	9	109,574,412 - 109,575,488 (-)	NCBI		HuRef
CHM1_1	9	140,263,431 - 140,264,507 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	149,457,928 - 149,461,077 (-)	NCBI		T2T-CHM13v2.0

Rnf208
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	25,132,941 - 25,134,273 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	25,132,941 - 25,134,274 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	25,242,929 - 25,244,261 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	25,242,929 - 25,244,262 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	25,098,449 - 25,099,781 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	25,064,947 - 25,066,271 (+)	NCBI		MGSCv36	mm8
Celera	2	24,970,856 - 24,972,188 (+)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	17.1	NCBI

Rnf208
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	5,219,425 - 5,220,228 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	5,219,250 - 5,223,043 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNF208
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	2,176,273 - 2,179,435 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	2,179,330 - 2,181,768 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	108,279,801 - 108,281,695 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	137,248,585 - 137,249,788 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	137,248,765 - 137,249,550 (-)	Ensembl	panpan1.1		panPan2

RNF208
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	48,452,147 - 48,453,585 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	48,452,622 - 48,453,416 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	47,637,974 - 47,639,807 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	49,312,827 - 49,314,660 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	49,313,696 - 49,314,490 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	48,089,229 - 48,091,062 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	48,388,040 - 48,389,873 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	48,435,199 - 48,437,032 (+)	NCBI		UU_Cfam_GSD_1.0

Rnf208
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	202,604,290 - 202,605,974 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936669	769,076 - 770,772 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF208
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	1	314,151,765 - 314,153,643 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF208
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	964,434 - 968,163 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	968,438 - 969,223 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
ChlSab1.1 Ensembl	12	968,438 - 969,223 (+)	NCBI	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666058	4,336,538 - 4,339,864 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf208
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	734,629 - 735,435 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	733,711 - 735,605 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rnf208
9 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	48
Count of miRNA genes:	43
Interacting mature miRNAs:	45
Transcripts:	ENSRNOT00000014087
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	27494778	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	31158234	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	33230976	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	diastolic blood pressure (CMO:0000005)	3	1	33278763	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	33278763	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
1358185	Ept6	Estrogen-induced pituitary tumorigenesis QTL 6	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6537645	10778823	Rat
2292615	Ept17	Estrogen-induced pituitary tumorigenesis QTL 17	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6537645	10778823	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		2	2		2			74	27	25
Low	2	31	36	22	19	22		1		8	16	11
Below cutoff		10	16	14		14	7	9					7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105655	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000014087 ⟹ ENSRNOP00000014087

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	8,058,397 - 8,059,721 (+)	Ensembl
Rnor_6.0 Ensembl	3	2,462,466 - 2,463,790 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106003 ⟹ ENSRNOP00000093881

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	8,043,963 - 8,059,844 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108034 ⟹ ENSRNOP00000090406

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	8,058,013 - 8,059,844 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111128 ⟹ ENSRNOP00000096761

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	8,043,685 - 8,059,844 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000116000 ⟹ ENSRNOP00000091105

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	8,044,178 - 8,059,844 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117799 ⟹ ENSRNOP00000076497

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	8,043,963 - 8,059,721 (+)	Ensembl

RefSeq Acc Id:

NM_001109195 ⟹ NP_001102665

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	28,456,555 - 28,457,879 (+)	NCBI
mRatBN7.2	3	8,058,397 - 8,059,721 (+)	NCBI
Rnor_6.0	3	2,462,466 - 2,463,790 (+)	NCBI
Rnor_5.0	3	2,443,879 - 2,445,203 (+)	NCBI
RGSC_v3.4	3	3,408,497 - 3,409,821 (+)	RGD
Celera	3	2,884,946 - 2,886,270 (+)	RGD

Sequence:

show sequence

GGGACTGCTGACCTCTGCTACAGGAGGAGGCCCCTCCACGCCCCCTTGCCAGCCTCAGCAGACA
GAGACCCTGGGCCTGGCAGGACCAGGATGCAGCCCCTTCTCTTCCCCCACGTCCCCACCCAACA
CCCCCACCTGTGCCAACGTCCAGTCTGACTGTAGAGAGCCGGATGCCAGCTGACCCTGGGCCTG
AGGTGGGCAGTGGATGGCCGGGCCTCCTCATGTCCTGCCTGAAAGGCCCCCATGTCATCCTCAA
AATGGAGGCCATGAAAATTGTCCACCCTGAAAAGTTCCCTGAGCTCCCAGCGGCCACCCCCTGC
TTCCCACCTGCACCCAGGCCCACTCCCACTCTGGCACCCAAGCGTGCTTGGCCCTCAGACACAG
AGATCATTGTCAACCAGGCATGTGGGGGGGACATGCCTACCTTGGAAGGAGCATCCCACACTCC
ACCCTTGCCAAGGCGGCCCCGCAAGGGCAGTTCTGAGTTGGGCTTCCCCCGGGTGGCACCGGTG
GATGAGGTCATTGTAAATCAGTATGTGATTCGACCTGGCCCAACAGCCTCTGCACCTTCATCAT
CTGGGCCAGTGATAGCAGGTGAGCCCCTGGAATGCCCGACCTGTGGGCACACATACAACGTCAC
TCAACGGCGGCCCCGTGTGCTGTCTTGCCTGCACTCCGTGTGTGAGCAGTGCCTGCAGATTCTT
TACGAGTCTTGCCCTAAGTACAAGTTCATCTCCTGTCCCACCTGCCACCGTGAGACTGTGCTCT
TCACTGACTATGGCCTGGCTGCACTGGCTGTCAACACATCCATCCTGAGCCGCTTGCCACCTGA
AGCCCTGACTGCCCCATCCGGTGGCCAGTGGGGGGGTGAATCTGAAGGCAGCTGCTACCAGACC
TTCCGGCAGTACTGTGGGGCTGCATGCACCTGCCATGTGCGGAACCCGCTATCTGCCTGTTCCA
TCATGTAGTGTCCACCTGCCCACTACTGCCTGCAGGCCCTTGCTCGCCGCTTCTTCGGGGAACT
GGCTTTGTCCTGTTGCCCGCTGACCCTCTCTTGCCCACTGTGGTTTCTGGCCCTACCCTGCGTG
GCATTGTCGCTGCAGCCAACTTTGCCATTAAAACTCTTTGCCAAAGTTT

hide sequence

RefSeq Acc Id:

XM_039105655 ⟹ XP_038961583

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	28,455,836 - 28,457,878 (+)	NCBI
mRatBN7.2	3	8,057,808 - 8,059,720 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102665	(Get FASTA)	NCBI Sequence Viewer
	XP_038961583	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL93625	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014087
	ENSRNOP00000014087.3
	ENSRNOP00000076497.1
	ENSRNOP00000090406
	ENSRNOP00000090406.1
	ENSRNOP00000091105.1
	ENSRNOP00000093881.1
	ENSRNOP00000096761.1

RefSeq Acc Id:

NP_001102665 ⟸ NM_001109195

- UniProtKB:

D4ADR3 (UniProtKB/TrEMBL), A6JT22 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPADPGPEVGSGWPGLLMSCLKGPHVILKMEAMKIVHPEKFPELPAATPCFPPAPRPTPTLAPK
RAWPSDTEIIVNQACGGDMPTLEGASHTPPLPRRPRKGSSELGFPRVAPVDEVIVNQYVIRPGP
TASAPSSSGPVIAGEPLECPTCGHTYNVTQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPT
CHRETVLFTDYGLAALAVNTSILSRLPPEALTAPSGGQWGGESEGSCYQTFRQYCGAACTCHVR
NPLSACSIM

hide sequence

RefSeq Acc Id:

ENSRNOP00000014087 ⟸ ENSRNOT00000014087

RefSeq Acc Id:	XP_038961583 ⟸ XM_039105655
- Peptide Label:	isoform X1
- UniProtKB:	D4ADR3 (UniProtKB/TrEMBL), A6JT22 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000090406 ⟸ ENSRNOT00000108034

RefSeq Acc Id:

ENSRNOP00000076497 ⟸ ENSRNOT00000117799

RefSeq Acc Id:

ENSRNOP00000096761 ⟸ ENSRNOT00000111128

RefSeq Acc Id:

ENSRNOP00000093881 ⟸ ENSRNOT00000106003

RefSeq Acc Id:

ENSRNOP00000091105 ⟸ ENSRNOT00000116000

Protein Domains

RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ADR3-F1-model_v2	AlphaFold	D4ADR3	1-265	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565957	AgrOrtholog
BioCyc Gene	G2FUF-50470	BioCyc
Ensembl Genes	ENSRNOG00000010607	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000014087	ENTREZGENE
	ENSRNOT00000014087.5	UniProtKB/TrEMBL
	ENSRNOT00000106003.1	UniProtKB/TrEMBL
	ENSRNOT00000108034.1	UniProtKB/TrEMBL
	ENSRNOT00000111128.1	UniProtKB/TrEMBL
	ENSRNOT00000116000.1	UniProtKB/TrEMBL
	ENSRNOT00000117799.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
InterPro	RNF208_RING-HC	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
KEGG Report	rno:499748	UniProtKB/TrEMBL
NCBI Gene	499748	ENTREZGENE
PANTHER	PTHR22791:SF3	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
PhenoGen	Rnf208	PhenoGen
PROSITE	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000010607	RatGTEx
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	A6JT22	ENTREZGENE, UniProtKB/TrEMBL
	D4ADR3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Rnf208	ring finger protein 208	RGD1565957_predicted	similar to RIKEN cDNA 1110061N23 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1565957_predicted	similar to RIKEN cDNA 1110061N23 (predicted)	LOC499748	similar to RIKEN cDNA 1110061N23	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC499748	similar to RIKEN cDNA 1110061N23			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar